Page last updated: 2024-10-23

aspirin and Acute-Phase Reaction

aspirin has been researched along with Acute-Phase Reaction in 11 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Acute-Phase Reaction: An early local inflammatory reaction to insult or injury that consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma.

Research Excerpts

ExcerptRelevanceReference
"To compare the efficacy of low-dose or no aspirin with conventional high-dose aspirin for the initial treatment in the acute-phase of Kawasaki disease (KD)."9.12Low-dose or no aspirin administration in acute-phase Kawasaki disease: a meta-analysis and systematic review. ( Chiang, MH; Liu, HE; Wang, JL, 2021)
"To compare the efficacy of low-dose or no aspirin with conventional high-dose aspirin for the initial treatment in the acute-phase of Kawasaki disease (KD)."5.12Low-dose or no aspirin administration in acute-phase Kawasaki disease: a meta-analysis and systematic review. ( Chiang, MH; Liu, HE; Wang, JL, 2021)
"Acetylsalicic acid and indomethacin suppress the increase of alpha-amanitin sensitive RNA synthesis (pre-mRNA), but not that of alpha-amanitin resistant RNA synthesis (pre-rRNA), which occur in liver nuclei a few hours after the start of turpentine-induced inflammation in the skin."3.67Prostaglandin synthesis and early biochemical events in the liver cells during the acute-phase response. ( Aletti, MG; Bernelli-Zazzera, A; Ferioli, ME; Piccoletti, R; Scalabrino, G, 1987)
"  In Kawasaki disease (KD), endothelial damage and an elevation in coagulant factors provoke thrombosis."1.46[Transient detection of lupus anticoagulant in acute phase of Kawasaki disease]. ( Imadome, KI; Ishiguro, A; Ito, S; Kobayashi, T; Kubota, M; Masuda, H; Nariai, R; Ono, H, 2017)
"Fever is a part of the acute phase response, a generalized reaction to infection or inflammation initiated by interleukin-1 (IL-1)."1.27Fever. What to do and what not to do. ( Rosenthal, TC; Silverstein, DA, 1988)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's1 (9.09)18.2507
2000's5 (45.45)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Chiang, MH1
Liu, HE1
Wang, JL1
Nariai, R1
Kobayashi, T1
Masuda, H1
Ono, H1
Imadome, KI1
Kubota, M1
Ito, S1
Ishiguro, A1
Li, JJ1
Fang, CH1
Nascimento-Silva, V1
Arruda, MA1
Barja-Fidalgo, C1
Villela, CG1
Fierro, IM1
Ito, Y1
Mori, A1
Yonemura, K1
Hashimoto, Y1
Hirano, T1
Uchino, M1
Yamaguchi, T1
Chamorro, A1
Obach, V1
Vila, N1
Revilla, M1
Cervera, A1
Ascaso, C1
Tanahashi, N1
Guilbaud, G1
Kayser, V1
Benoist, JM1
Gautron, M1
Piccoletti, R1
Aletti, MG1
Ferioli, ME1
Scalabrino, G1
Bernelli-Zazzera, A1
Rosenthal, TC1
Silverstein, DA1

Reviews

3 reviews available for aspirin and Acute-Phase Reaction

ArticleYear
Low-dose or no aspirin administration in acute-phase Kawasaki disease: a meta-analysis and systematic review.
    Archives of disease in childhood, 2021, Volume: 106, Issue:7

    Topics: Acute-Phase Reaction; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Child;

2021
[Current status and future prospects in the treatment of acute-phase cerebral infarction].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1999, Sep-10, Volume: 88, Issue:9

    Topics: Acute-Phase Reaction; Aspirin; Brain Edema; Calcium Channel Blockers; Cerebral Infarction; Fibrinoly

1999
[Antithrombotic therapy in cerebral infarction].
    Rinsho shinkeigaku = Clinical neurology, 2000, Volume: 40, Issue:12

    Topics: Acute-Phase Reaction; Anticoagulants; Aspirin; Atrial Fibrillation; Cerebral Infarction; Heparin; Hu

2000

Trials

1 trial available for aspirin and Acute-Phase Reaction

ArticleYear
Comparison of the acute-phase response in patients with ischemic stroke treated with high-dose heparin or aspirin.
    Journal of the neurological sciences, 2000, Sep-01, Volume: 178, Issue:1

    Topics: Acute-Phase Reaction; Aged; Analysis of Variance; Aspirin; Brain Ischemia; Female; Fibrinolytic Agen

2000

Other Studies

7 other studies available for aspirin and Acute-Phase Reaction

ArticleYear
[Transient detection of lupus anticoagulant in acute phase of Kawasaki disease].
    Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2017, Volume: 40, Issue:6

    Topics: Acute-Phase Reaction; Aspirin; Child, Preschool; Humans; Immunoglobulins, Intravenous; Lupus Coagula

2017
C-reactive protein is not only an inflammatory marker but also a direct cause of cardiovascular diseases.
    Medical hypotheses, 2004, Volume: 62, Issue:4

    Topics: Acute-Phase Reaction; Aspirin; Atorvastatin; Biomarkers; C-Reactive Protein; Cardiovascular Diseases

2004
Novel lipid mediator aspirin-triggered lipoxin A4 induces heme oxygenase-1 in endothelial cells.
    American journal of physiology. Cell physiology, 2005, Volume: 289, Issue:3

    Topics: Acute-Phase Reaction; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Int

2005
[Late-onset hemorrhagic infarction in patients with patent foramen ovale: reports of two cases].
    Rinsho shinkeigaku = Clinical neurology, 2007, Volume: 47, Issue:9

    Topics: Acute-Phase Reaction; Aged; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Foramen Ovale, Patent

2007
Modifications in the responsiveness of rat ventrobasal thalamic neurons at different stages of carrageenin-produced inflammation.
    Brain research, 1986, Oct-15, Volume: 385, Issue:1

    Topics: Action Potentials; Acute-Phase Reaction; Animals; Aspirin; Carrageenan; Inflammation; Lidocaine; Mal

1986
Prostaglandin synthesis and early biochemical events in the liver cells during the acute-phase response.
    Research communications in chemical pathology and pharmacology, 1987, Volume: 56, Issue:3

    Topics: Acute-Phase Reaction; Animals; Aspirin; Dinoprost; Dinoprostone; Indomethacin; Inflammation; Liver;

1987
Fever. What to do and what not to do.
    Postgraduate medicine, 1988, Volume: 83, Issue:8

    Topics: Acetaminophen; Acute-Phase Reaction; Aspirin; Body Temperature Regulation; Cold Temperature; Fever;

1988