aspirin has been researched along with Acute Pain in 9 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Acute Pain: Intensely discomforting, distressful, or agonizing sensation associated with trauma or disease, with well-defined location, character, and timing.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study is to investigate if an orally administered combination of aspirin and ketamine will provide better analgesia than a ketamine alone in adult patients presenting to the Emergency Department (ED) with acute musculoskeletal pain." | 9.51 | Oral Aspirin/ketamine versus oral ketamine for emergency department patients with acute musculoskeletal pain. ( Barberan, C; Correa Bravo, S; Davis, A; Drapkin, J; Fassassi, C; Gerges, L; Gohel, A; Hossain, R; Likourezos, A; Motov, S; Niceforo, P; Silver, M, 2022) |
| "In total, 27 patients with stable cardiovascular, cerebrovascular or peripheral arterial disease and acute or chronic pain were identified and given dipyrone for at least 5 days in combination with low-dose aspirin." | 9.24 | Dipyrone (metamizole) markedly interferes with platelet inhibition by aspirin in patients with acute and chronic pain: A case-control study. ( Hohlfeld, T; Kienbaum, P; Pavlaković, G; Romann, L; Schmitz, A; Werdehausen, R, 2017) |
| "The purpose of this study is to investigate if an orally administered combination of aspirin and ketamine will provide better analgesia than a ketamine alone in adult patients presenting to the Emergency Department (ED) with acute musculoskeletal pain." | 5.51 | Oral Aspirin/ketamine versus oral ketamine for emergency department patients with acute musculoskeletal pain. ( Barberan, C; Correa Bravo, S; Davis, A; Drapkin, J; Fassassi, C; Gerges, L; Gohel, A; Hossain, R; Likourezos, A; Motov, S; Niceforo, P; Silver, M, 2022) |
| "In total, 27 patients with stable cardiovascular, cerebrovascular or peripheral arterial disease and acute or chronic pain were identified and given dipyrone for at least 5 days in combination with low-dose aspirin." | 5.24 | Dipyrone (metamizole) markedly interferes with platelet inhibition by aspirin in patients with acute and chronic pain: A case-control study. ( Hohlfeld, T; Kienbaum, P; Pavlaković, G; Romann, L; Schmitz, A; Werdehausen, R, 2017) |
| "Aspirin has been used in the management of postpartum perineal pain, and its effectiveness and safety should be assessed." | 2.66 | Aspirin (single dose) for perineal pain in the early postpartum period. ( Grivell, RM; Shepherd, E, 2020) |
| "Aspirin has been used in the management of postpartum perineal pain and its effectiveness and safety should be assessed." | 2.55 | Aspirin (single dose) for perineal pain in the early postpartum period. ( Grivell, RM; Molakatalla, S; Shepherd, E, 2017) |
| "Severe acute pain is typically treated with potent opioids." | 2.49 | Pharmacologic therapy for acute pain. ( Azadfard, M; Blondell, RD; Wisniewski, AM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, A | 2 |
| Fassassi, C | 2 |
| Dove, D | 1 |
| Drapkin, J | 2 |
| Likourezos, A | 2 |
| Gohel, A | 2 |
| Favale, P | 1 |
| Hossain, R | 2 |
| Butt, M | 1 |
| Gerges, L | 2 |
| Motov, S | 2 |
| Barberan, C | 1 |
| Correa Bravo, S | 1 |
| Silver, M | 1 |
| Niceforo, P | 1 |
| Shepherd, E | 2 |
| Grivell, RM | 2 |
| Blondell, RD | 1 |
| Azadfard, M | 1 |
| Wisniewski, AM | 1 |
| Kröger, IL | 1 |
| May, A | 1 |
| Voelker, M | 1 |
| Schachtel, BP | 1 |
| Cooper, SA | 1 |
| Gatoulis, SC | 1 |
| Schmitz, A | 1 |
| Romann, L | 1 |
| Kienbaum, P | 1 |
| Pavlaković, G | 1 |
| Werdehausen, R | 1 |
| Hohlfeld, T | 1 |
| Molakatalla, S | 1 |
| Du, Y | 1 |
| Ellert, U | 1 |
| Zhuang, W | 1 |
| Knopf, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Analgesic Efficacy of Orally Administered VTS-K (Liquid Oral Ketamine Taken Simultaneously With VTS-Aspirin) for Pain Management of Adult ED Patients Presenting to the ED With Acute Musculoskeletal Pain[NCT04702555] | 25 participants (Actual) | Observational | 2021-01-08 | Completed | |||
| A Comparison of Proprietary Formulations of Oral Ketamine + Aspirin and Oral Ketamine Alone in Adult Patients Presenting to the ED With Acute Musculoskeletal Pain: Prospective, Randomized, Open-Label, Clinical Trial.[NCT04860804] | Phase 4 | 60 participants (Actual) | Interventional | 2021-04-22 | Completed | ||
| Onset of Action of a Fast Release Aspirin Tablet and Acetaminophen Caplet in Sore Throat Pain[NCT01453400] | Phase 3 | 177 participants (Actual) | Interventional | 2011-09-27 | Completed | ||
| Comparative Onset of Action of a Fast Release Aspirin Tablet in a Dental Impaction Pain Model[NCT01420094] | Phase 3 | 510 participants (Actual) | Interventional | 2011-06-16 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reduction of pain scores on numeric rating pain scale (NRS) at 60 minutes mark form the baseline. The NRS is an 11 item Likert Scale ranging from 0 (no pain) to 10 (very severe pain) with 5 indicating moderate pain. (NCT04860804)
Timeframe: 60 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| AOK Group | 2.18 |
| OK Group | 4.01 |
3 reviews available for aspirin and Acute Pain
| Article | Year |
|---|---|
Aspirin (single dose) for perineal pain in the early postpartum period.
Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Episiotomy; Female; Humans; Obstetric | 2020 |
Pharmacologic therapy for acute pain.
Topics: Acetaminophen; Acute Pain; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammato | 2013 |
Aspirin (single dose) for perineal pain in the early postpartum period.
Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Obstetric Labor Compli | 2017 |
4 trials available for aspirin and Acute Pain
| Article | Year |
|---|---|
Oral Aspirin/ketamine versus oral ketamine for emergency department patients with acute musculoskeletal pain.
Topics: Acute Pain; Adult; Analgesics; Aspirin; Double-Blind Method; Emergency Service, Hospital; Humans; Ke | 2022 |
Central effects of acetylsalicylic acid on trigeminal-nociceptive stimuli.
Topics: Acute Pain; Adult; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Gyrus Cinguli; Humans; Ma | 2014 |
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal | 2016 |
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal | 2016 |
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal | 2016 |
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal | 2016 |
Dipyrone (metamizole) markedly interferes with platelet inhibition by aspirin in patients with acute and chronic pain: A case-control study.
Topics: Acute Pain; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platele | 2017 |
2 other studies available for aspirin and Acute Pain
| Article | Year |
|---|---|
Analgesic Efficacy of Oral Aspirin/Ketamine Combination for Management of Acute Musculoskeletal Pain in the Emergency Department - A Proof of Concept Pilot Study.
Topics: Acute Pain; Adult; Analgesics; Aspirin; Double-Blind Method; Emergency Service, Hospital; Humans; Ke | 2022 |
Analgesic use in a national community sample of German children and adolescents.
Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics; Aspirin; Child; Child, Preschool; Chronic Pain; F | 2012 |