aspirin has been researched along with Acute Kidney Injury in 83 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether aspirin compared with placebo, and clonidine compared with placebo, alters the risk of perioperative acute kidney injury." | 9.19 | Perioperative aspirin and clonidine and risk of acute kidney injury: a randomized clinical trial. ( Acedillo, R; Amir, M; Bergese, S; Biccard, B; Bidgoli, SJ; Cata, JP; Cegarra, V; Chan, MT; Chan, V; Clanchet, Mde N; Cuerden, M; Devereaux, PJ; Dresser, G; Fleischmann, E; Font, A; Forget, P; Garg, AX; Gomez, MF; Jones, PM; Kumar, P; Kurz, A; Leslie, K; Malaga, G; Martinsen, K; Mehra, B; Meyhoff, CS; Mizera, R; Mrkobrada, M; Myles, P; Painter, T; Parikh, CR; Parlow, J; Pasin, L; Robinson, A; Roshanov, PS; Sessler, DI; Srinathan, S; Tiboni, M; Torres, D; VanHelder, T; Villar, JC; Walsh, M; Whitlock, R; Wijeysundera, DN; Yusuf, S, 2014) |
| "Although the effect of rectal indomethacin in post-endoscopic retrograde cholangiopancreatography pancreatitis is well established, the effect of aspirin on acute pancreatitis (AP) is not well studied." | 8.31 | Does use of long-term aspirin impact outcomes in patients with acute pancreatitis? ( Chaudhry, H; Dukovic, D; Kohli, I; Prajapati, D; Sharma, R; Singla, P; Sohal, A; Yang, J, 2023) |
| "To test the hypothesis that preoperative aspirin administered within 24 hours before coronary artery bypass grafting (CABG) could reduce the incidence of postoperative acute kidney injury (AKI) following CABG." | 7.96 | Association between preoperative aspirin and acute kidney injury following coronary artery bypass grafting. ( Aboul-Hassan, SS; Cichon, R; Marczak, J; Nawotka, M; Peksa, M; Stanislawski, R; Stankowski, T, 2020) |
| "The association between preoperative aspirin use and postoperative acute kidney injury (AKI) in cardiovascular surgery is unclear." | 7.85 | Preoperative aspirin use and acute kidney injury after cardiac surgery: A propensity-score matched observational study. ( Bahk, JH; Hur, M; Kim, JT; Kim, M; Kim, WH; Koo, CH; Lee, HC; Park, SK, 2017) |
| "The first case of haemolytic anaemia with thrombocytopenia and acute renal failure induced by ingestion of aspirin in a 22-year old woman is reported." | 7.67 | [Immunoallergic hemolytic anemia, thrombopenia and acute renal failure induced by aspirin]. ( Debray, J; Habibi, B; Hubert, D; Krulik, M, 1984) |
| " The adequate hydration group received continuous intravenous infusion of isosorbide dinitrate combined with intravenous infusion of isotonic saline at a rate of 1." | 6.90 | Prevention of contrast-induced nephropathy by adequate hydration combined with isosorbide dinitrate for patients with renal insufficiency and congestive heart failure. ( Chen, Y; Dong, W; Guo, J; Liu, CF; Qian, G; Wang, J, 2019) |
| "Aspirin was found to have a significant protective effect against cisplatin-induced acute kidney injury, as evidenced by the reduction in levels of ROS, NO, and MDA and the increase in T-AOC, CAT, SOD, and GSH." | 5.91 | Aspirin alleviates cisplatin-induced acute kidney injury through the AMPK-PGC-1α signaling pathway. ( Ge, R; Hu, M; Jin, S; Liu, Y; Mu, J; Tong, D; Xu, E, 2023) |
| "The aspirin was stopped immediately." | 5.39 | Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis). ( Alghamdi, M; Alhussaini, H; Almalki, AS; Alokaily, FA, 2013) |
| "In many parts of Europe, nephropathia epidemica (NE) is an endemic zoonosis." | 5.38 | Ibuprofen or diclofenac is associated with more severe acute kidney injury in nephropathia epidemica. ( Leicht-Biener, U; Mucsi, I; Seitz, K; Wagner, R, 2012) |
| "To determine whether aspirin compared with placebo, and clonidine compared with placebo, alters the risk of perioperative acute kidney injury." | 5.19 | Perioperative aspirin and clonidine and risk of acute kidney injury: a randomized clinical trial. ( Acedillo, R; Amir, M; Bergese, S; Biccard, B; Bidgoli, SJ; Cata, JP; Cegarra, V; Chan, MT; Chan, V; Clanchet, Mde N; Cuerden, M; Devereaux, PJ; Dresser, G; Fleischmann, E; Font, A; Forget, P; Garg, AX; Gomez, MF; Jones, PM; Kumar, P; Kurz, A; Leslie, K; Malaga, G; Martinsen, K; Mehra, B; Meyhoff, CS; Mizera, R; Mrkobrada, M; Myles, P; Painter, T; Parikh, CR; Parlow, J; Pasin, L; Robinson, A; Roshanov, PS; Sessler, DI; Srinathan, S; Tiboni, M; Torres, D; VanHelder, T; Villar, JC; Walsh, M; Whitlock, R; Wijeysundera, DN; Yusuf, S, 2014) |
| " In this review, we discuss the possible repurposing of drugs approved for cardiovascular diseases, such as β-blockers, angiotensin converting enzyme inhibitors (ACE-Is), angiotensin II receptor blockers (ARBs), statins, aspirin, cardiac glycosides and low-molecular-weight heparins (LMWHs)." | 5.05 | Repurposing of drugs approved for cardiovascular diseases: Opportunity or mirage? ( Camera, M; Castiglioni, L; Gelosa, P; Sironi, L, 2020) |
| "Although the effect of rectal indomethacin in post-endoscopic retrograde cholangiopancreatography pancreatitis is well established, the effect of aspirin on acute pancreatitis (AP) is not well studied." | 4.31 | Does use of long-term aspirin impact outcomes in patients with acute pancreatitis? ( Chaudhry, H; Dukovic, D; Kohli, I; Prajapati, D; Sharma, R; Singla, P; Sohal, A; Yang, J, 2023) |
| " Therapeutic strategies using lipid mediators, such as aspirin-triggered resolvin D1 (ATRvD1), can contribute to the resolution of acute and chronic inflammation." | 4.02 | ATRvD1 Attenuates Renal Tubulointerstitial Injury Induced by Albumin Overload in Sepsis-Surviving Mice. ( Almeida-Souza, F; Benjamim, CF; Calabrese, KS; Calcia, TBB; Caruso-Neves, C; Guilherme, RF; Lemos, FS; Neves, JS; Silva, CP; Silva, JBNF, 2021) |
| "To test the hypothesis that preoperative aspirin administered within 24 hours before coronary artery bypass grafting (CABG) could reduce the incidence of postoperative acute kidney injury (AKI) following CABG." | 3.96 | Association between preoperative aspirin and acute kidney injury following coronary artery bypass grafting. ( Aboul-Hassan, SS; Cichon, R; Marczak, J; Nawotka, M; Peksa, M; Stanislawski, R; Stankowski, T, 2020) |
| "The association between preoperative aspirin use and postoperative acute kidney injury (AKI) in cardiovascular surgery is unclear." | 3.85 | Preoperative aspirin use and acute kidney injury after cardiac surgery: A propensity-score matched observational study. ( Bahk, JH; Hur, M; Kim, JT; Kim, M; Kim, WH; Koo, CH; Lee, HC; Park, SK, 2017) |
| " Of all patients, 3585 met the inclusion criteria and underwent the analysis to determine the association of preoperative aspirin with incidence of acute kidney injury (AKI) and death based on estimated glomerular filtration rate (eGFR)." | 3.81 | Evidence for preoperative aspirin improving major outcomes in patients with chronic kidney disease undergoing cardiac surgery: a cohort study. ( Diehl, J; Goldhammer, J; He, J; Li, Z; Liu, H; Sun, J; Sun, W; Tao, L; Yao, L; Young, N, 2015) |
| "We aimed to identify the risk factors for acute kidney injury in infants who have received ketorolac after a cardiac surgical procedure by identifying patients with a > or = 50% increase in serum creatinine from baseline and matching them by age with three controls that had < 50% increase in serum creatinine." | 3.79 | Ketorolac-associated renal morbidity: risk factors in cardiac surgical infants. ( Cabrera, A; Moffett, BS, 2013) |
| "The first case of haemolytic anaemia with thrombocytopenia and acute renal failure induced by ingestion of aspirin in a 22-year old woman is reported." | 3.67 | [Immunoallergic hemolytic anemia, thrombopenia and acute renal failure induced by aspirin]. ( Debray, J; Habibi, B; Hubert, D; Krulik, M, 1984) |
| "Analgesic nephropathy is part of a wider clinical syndrome associated with the abuse of APC compounds, that is, a minimum total intake of 2 kg of aspirin or phenacetin." | 3.65 | Analgesic nephropathy. ( Nanra, RS, 1976) |
| " The adequate hydration group received continuous intravenous infusion of isosorbide dinitrate combined with intravenous infusion of isotonic saline at a rate of 1." | 2.90 | Prevention of contrast-induced nephropathy by adequate hydration combined with isosorbide dinitrate for patients with renal insufficiency and congestive heart failure. ( Chen, Y; Dong, W; Guo, J; Liu, CF; Qian, G; Wang, J, 2019) |
| " Chronic administration of aspirin alone over 18 to 68 weeks in doses of 120 to 500 mg/kg/d has been reported to cause renal papillary necrosis in rats." | 2.39 | Does aspirin cause acute or chronic renal failure in experimental animals and in humans? ( D'Agati, V, 1996) |
| "Aspirin was found to have a significant protective effect against cisplatin-induced acute kidney injury, as evidenced by the reduction in levels of ROS, NO, and MDA and the increase in T-AOC, CAT, SOD, and GSH." | 1.91 | Aspirin alleviates cisplatin-induced acute kidney injury through the AMPK-PGC-1α signaling pathway. ( Ge, R; Hu, M; Jin, S; Liu, Y; Mu, J; Tong, D; Xu, E, 2023) |
| "The aspirin was stopped immediately." | 1.39 | Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis). ( Alghamdi, M; Alhussaini, H; Almalki, AS; Alokaily, FA, 2013) |
| "In many parts of Europe, nephropathia epidemica (NE) is an endemic zoonosis." | 1.38 | Ibuprofen or diclofenac is associated with more severe acute kidney injury in nephropathia epidemica. ( Leicht-Biener, U; Mucsi, I; Seitz, K; Wagner, R, 2012) |
| " Serious adverse events were uncommon but despite this aspirin cost the NHS between 6 and 25 times the cost of aspirin tablets due to dispensing costs and the cost of managing adverse effects." | 1.32 | Cardiovascular prophylaxis with aspirin: costs of supply and management of upper gastrointestinal and renal toxicity. ( Cleland, JG; Davey, PG; MacDonald, TM; McMahon, AD; Morant, SV, 2004) |
| "However, the major mechanism for the acute renal failure was thought to be related to inhibition of renal prostaglandin synthesis in the face of compromised renal hemodynamics secondary to alcohol-induced volume depletion." | 1.28 | Acute renal failure following binge drinking and nonsteroidal antiinflammatory drugs. ( Iliopoulos, O; Oberley, TD; Parthasarathy, R; Wen, SF, 1992) |
| "Eleven of these children developed acute renal insufficiency." | 1.28 | Drug-induced haemolysis and renal failure in children with glucose-6-phosphate dehydrogenase deficiency in Afghanistan. ( Choudhry, VP; Fazel, I; Ghafary, A; Ghani, R; Qureshi, MA; Zaher, M, 1990) |
| "Phenacetin pretreatment (597 mg/kg) was less effective, while paracetamol (503 mg/kg) was without effect in this regard." | 1.26 | Studies on the modification of renal lesions due to aspirin and oxyphenbutazone in the rat and the effects on the kidney of 2:4 dinitrophenol. ( Arnold, L; Collins, C; Starmer, GA, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (42.17) | 18.7374 |
| 1990's | 6 (7.23) | 18.2507 |
| 2000's | 6 (7.23) | 29.6817 |
| 2010's | 26 (31.33) | 24.3611 |
| 2020's | 10 (12.05) | 2.80 |
| Authors | Studies |
|---|---|
| Silva, JBNF | 1 |
| Calcia, TBB | 1 |
| Silva, CP | 1 |
| Guilherme, RF | 1 |
| Almeida-Souza, F | 1 |
| Lemos, FS | 1 |
| Calabrese, KS | 1 |
| Caruso-Neves, C | 1 |
| Neves, JS | 1 |
| Benjamim, CF | 1 |
| Mittal, A | 1 |
| Tamer, P | 1 |
| Shah, I | 1 |
| Cortes, A | 1 |
| Hinman, AD | 1 |
| Tong, D | 1 |
| Xu, E | 1 |
| Ge, R | 1 |
| Hu, M | 1 |
| Jin, S | 1 |
| Mu, J | 1 |
| Liu, Y | 1 |
| Chaudhry, H | 1 |
| Sohal, A | 1 |
| Dukovic, D | 1 |
| Kohli, I | 1 |
| Sharma, R | 1 |
| Singla, P | 1 |
| Prajapati, D | 1 |
| Yang, J | 1 |
| Liu, H | 3 |
| Li, J | 1 |
| Chen, M | 1 |
| Yang, T | 1 |
| Ruan, Z | 1 |
| Su, J | 1 |
| Xing, Y | 1 |
| Aboul-Hassan, SS | 1 |
| Marczak, J | 1 |
| Stankowski, T | 1 |
| Peksa, M | 1 |
| Nawotka, M | 1 |
| Stanislawski, R | 1 |
| Cichon, R | 1 |
| Shanewise, JS | 1 |
| Gelosa, P | 1 |
| Castiglioni, L | 1 |
| Camera, M | 1 |
| Sironi, L | 1 |
| Mitsuboshi, S | 1 |
| Niimura, T | 1 |
| Zamami, Y | 1 |
| Kinter, CW | 1 |
| Saxon, GE | 1 |
| Ahmad, M | 1 |
| Berhane, H | 1 |
| Gensler, L | 1 |
| Khosroshahi, A | 1 |
| Hatakeyama, Y | 1 |
| Horino, T | 1 |
| Matsumoto, T | 1 |
| Terada, Y | 1 |
| Okuhara, Y | 1 |
| Hur, M | 1 |
| Koo, CH | 1 |
| Lee, HC | 1 |
| Park, SK | 1 |
| Kim, M | 1 |
| Kim, WH | 1 |
| Kim, JT | 1 |
| Bahk, JH | 1 |
| Lazar, HL | 1 |
| Tiewsoh, K | 1 |
| Sharma, D | 1 |
| Jindal, AK | 1 |
| Bhisikar, S | 1 |
| Suri, D | 1 |
| Singh, S | 1 |
| Uber, AM | 1 |
| Montez-Rath, ME | 1 |
| Kwiatkowski, DM | 1 |
| Krawczeski, CD | 1 |
| Sutherland, SM | 1 |
| Qian, G | 1 |
| Liu, CF | 1 |
| Guo, J | 1 |
| Dong, W | 1 |
| Wang, J | 1 |
| Chen, Y | 1 |
| Hu, X | 1 |
| Liang, Y | 1 |
| Zhao, H | 1 |
| Zhao, M | 1 |
| Alokaily, FA | 1 |
| Alghamdi, M | 1 |
| Almalki, AS | 1 |
| Alhussaini, H | 1 |
| Amekoudi, EY | 1 |
| Sabi, KA | 1 |
| Noto Kadou Kaza, B | 1 |
| Garg, AX | 3 |
| Kurz, A | 2 |
| Sessler, DI | 3 |
| Cuerden, M | 2 |
| Robinson, A | 2 |
| Mrkobrada, M | 2 |
| Parikh, C | 1 |
| Mizera, R | 2 |
| Jones, PM | 2 |
| Tiboni, M | 2 |
| Rodriguez, RG | 1 |
| Popova, E | 1 |
| Rojas Gomez, MF | 1 |
| Meyhoff, CS | 2 |
| Vanhelder, T | 2 |
| Chan, MT | 2 |
| Torres, D | 2 |
| Parlow, J | 2 |
| de Nadal Clanchet, M | 1 |
| Amir, M | 2 |
| Bidgoli, SJ | 2 |
| Pasin, L | 2 |
| Martinsen, K | 2 |
| Malaga, G | 2 |
| Myles, P | 2 |
| Acedillo, R | 2 |
| Roshanov, P | 1 |
| Walsh, M | 2 |
| Dresser, G | 2 |
| Kumar, P | 2 |
| Fleischmann, E | 2 |
| Villar, JC | 2 |
| Painter, T | 2 |
| Biccard, B | 2 |
| Bergese, S | 2 |
| Srinathan, S | 2 |
| Cata, JP | 2 |
| Chan, V | 2 |
| Mehra, B | 2 |
| Leslie, K | 2 |
| Whitlock, R | 2 |
| Devereaux, PJ | 3 |
| Chen, J | 1 |
| Shetty, S | 1 |
| Zhang, P | 1 |
| Gao, R | 1 |
| Hu, Y | 1 |
| Wang, S | 1 |
| Li, Z | 2 |
| Fu, J | 1 |
| Yao, L | 1 |
| Young, N | 1 |
| Sun, W | 1 |
| Goldhammer, J | 1 |
| Tao, L | 1 |
| He, J | 1 |
| Diehl, J | 1 |
| Sun, J | 2 |
| Mårtensson, J | 1 |
| Bellomo, R | 1 |
| Parikh, CR | 1 |
| Font, A | 1 |
| Cegarra, V | 1 |
| Gomez, MF | 1 |
| Clanchet, Mde N | 1 |
| Roshanov, PS | 1 |
| Wijeysundera, DN | 1 |
| Forget, P | 1 |
| Yusuf, S | 1 |
| Winkelmayer, WC | 1 |
| Finkel, KW | 1 |
| Allison, SJ | 1 |
| Shirota, T | 1 |
| Ikegami, T | 1 |
| Sugiyama, S | 1 |
| Kubota, K | 1 |
| Shimizu, A | 1 |
| Ohno, Y | 1 |
| Mita, A | 1 |
| Urata, K | 1 |
| Nakazawa, Y | 1 |
| Kobayashi, A | 1 |
| Iwaya, M | 1 |
| Miyagawa, S | 1 |
| Ponikowski, P | 1 |
| Ronco, C | 1 |
| Anker, SD | 1 |
| Joy, K | 1 |
| Dubois, S | 1 |
| Gibbons, C | 1 |
| Hargadon, J | 1 |
| Bédard, M | 1 |
| Pompilio, G | 1 |
| Filippini, S | 1 |
| Agrifoglio, M | 1 |
| Merati, E | 1 |
| Lauri, G | 1 |
| Salis, S | 1 |
| Alamanni, F | 1 |
| Parolari, A | 1 |
| Wagner, R | 1 |
| Leicht-Biener, U | 1 |
| Mucsi, I | 1 |
| Seitz, K | 1 |
| Arora, P | 1 |
| Kolli, H | 1 |
| Nainani, N | 1 |
| Nader, N | 1 |
| Lohr, J | 1 |
| Bozkurt, Y | 1 |
| Bozkurt, M | 1 |
| Turkçu, G | 1 |
| Sancaktutar, AA | 1 |
| Soylemez, H | 1 |
| Penbegul, N | 1 |
| Atar, M | 1 |
| Bodakcı, MN | 1 |
| Hatipoglu, NK | 1 |
| Yuksel, H | 1 |
| Kıbrıslı, E | 1 |
| Yavuz, C | 1 |
| Moffett, BS | 1 |
| Cabrera, A | 1 |
| Martínez, JG | 1 |
| Saus, C | 1 |
| Morey, A | 1 |
| Alarcón, A | 1 |
| Nogi, K | 1 |
| Taniguchi, H | 1 |
| Onoda, Y | 1 |
| CAMPBELL, EJ | 1 |
| MACLAURIN, RE | 1 |
| SMITH, WW | 1 |
| BERGEN, W | 1 |
| CONDON, JF | 1 |
| FENNELLY, JJ | 1 |
| LASKER, N | 1 |
| BEVERIDGE, GW | 1 |
| FORSHALL, W | 1 |
| MUNRO, JF | 1 |
| OWEN, JA | 1 |
| WESTON, IA | 1 |
| YOUNG, JV | 1 |
| HAYDON, GB | 1 |
| GRAY, CP | 1 |
| HECKER, SP | 1 |
| LEE, PR | 1 |
| Morant, SV | 1 |
| McMahon, AD | 2 |
| Cleland, JG | 1 |
| Davey, PG | 1 |
| MacDonald, TM | 2 |
| Rüster, M | 1 |
| Kiehntopf, M | 1 |
| Gröne, HJ | 1 |
| Wolf, G | 1 |
| Hubert, D | 1 |
| Habibi, B | 1 |
| Krulik, M | 1 |
| Debray, J | 1 |
| Clive, DM | 1 |
| Stoff, JS | 1 |
| Aul, C | 1 |
| Scharf, RE | 1 |
| Königshausen, T | 1 |
| Küppers, H | 1 |
| Grabensee, B | 1 |
| Chaudhari, A | 1 |
| Kirschenbaum, MA | 1 |
| Rupp, DJ | 1 |
| Seaton, RD | 1 |
| Wiegmann, TB | 1 |
| Rossi, E | 1 |
| Silvestri, MG | 1 |
| Manari, A | 1 |
| Savazzi, G | 1 |
| Migone, L | 1 |
| Snodgrass, W | 1 |
| Rumack, BH | 1 |
| Peterson, RG | 1 |
| Holbrook, ML | 1 |
| Evans, JM | 1 |
| McGregor, E | 1 |
| McGilchrist, MM | 1 |
| Jones, MC | 1 |
| White, G | 1 |
| McDevitt, DG | 1 |
| Toupin, LR | 1 |
| Blanchard, DG | 1 |
| D'Agati, V | 1 |
| Lieberthal, W | 1 |
| Fuhro, R | 1 |
| Andry, C | 1 |
| Valeri, CR | 1 |
| Rich, SA | 1 |
| Egido, J | 1 |
| Crespo, M | 1 |
| Sanchez, MG | 1 |
| Hernando, L | 1 |
| Benveniste, J | 1 |
| Ekert, H | 1 |
| Waters, KD | 1 |
| Kimberly, RP | 1 |
| Sherman, RL | 1 |
| Mouradian, J | 1 |
| Lockshin, MD | 1 |
| Emori, T | 1 |
| Takahashi, M | 1 |
| Nagase, S | 1 |
| Kennedy, A | 2 |
| Arnold, L | 3 |
| Collins, C | 3 |
| Starmer, GA | 3 |
| Nanra, RS | 1 |
| Parker, RW | 1 |
| Shaw, RE | 1 |
| Wen, SF | 1 |
| Parthasarathy, R | 1 |
| Iliopoulos, O | 1 |
| Oberley, TD | 1 |
| Yokota, M | 1 |
| Kambayashi, J | 1 |
| Sakon, M | 1 |
| Tahara, H | 1 |
| Shiba, E | 1 |
| Kawasaki, T | 1 |
| Mori, T | 1 |
| Choudhry, VP | 1 |
| Ghafary, A | 1 |
| Zaher, M | 1 |
| Qureshi, MA | 1 |
| Fazel, I | 1 |
| Ghani, R | 1 |
| Laffi, G | 1 |
| La Villa, G | 1 |
| Pinzani, M | 1 |
| Ciabattoni, G | 1 |
| Patrignani, P | 1 |
| Mannelli, M | 1 |
| Cominelli, F | 1 |
| Gentilini, P | 1 |
| Blaser, KU | 1 |
| Lämmle, B | 1 |
| Baños Gallardo, M | 1 |
| Claros González, I | 1 |
| Forascepi Roza, R | 1 |
| Argüelles Toraño, M | 1 |
| Christensen, LA | 1 |
| Schmidt, EB | 1 |
| Moss, AH | 1 |
| Riley, R | 1 |
| Murgo, A | 1 |
| Skaff, LA | 1 |
| Reeves, WB | 1 |
| Foley, RJ | 1 |
| Weinman, EJ | 1 |
| Hare, WS | 1 |
| Poynter, JD | 1 |
| Bergentz, SE | 1 |
| Andreasen, F | 1 |
| Done, AK | 1 |
| Temple, AR | 1 |
| Brown, CB | 1 |
| McMillan, JM | 1 |
| Bateman, CJ | 1 |
| Cattell, WR | 1 |
| Saluga, PG | 1 |
| Wajcner, G | 1 |
| Guedon, J | 1 |
| Chapman, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Chinese People's Liberation Army General Hospital[NCT02718521] | 400 participants (Anticipated) | Interventional | 2016-03-31 | Active, not recruiting | |||
| A Large, International, Placebo-controlled, Factorial Trial to Assess the Impact of Clonidine and Acetyl-salicylic Acid (ASA) in Patients Undergoing Noncardiac Surgery Who Are at Risk of a Perioperative Cardiovascular Event[NCT01082874] | Phase 3 | 10,010 participants (Actual) | Interventional | 2010-07-31 | Completed | ||
| A Phase II, Randomized, Single-Blind, Controlled Clinical Trial to Evaluate the Efficacy and Safety of Hemolink[Tm] (o-Raffinose Cross-Linked Human Hemoglobin) in Subjects Undergoing Primary Coronary Artery Bypass Grafting Surgery[NCT00038454] | Phase 2/Phase 3 | 180 participants | Interventional | Suspended | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01082874)
Timeframe: 30 days
| Intervention | participants (Number) |
|---|---|
| Active Clonidine and Active ASA | 173 |
| Active Clonidine and Placebo ASA | 194 |
| Placebo Clonidine and Active ASA | 178 |
| Placebo Clonidine and Placebo ASA | 161 |
10 reviews available for aspirin and Acute Kidney Injury
| Article | Year |
|---|---|
A Meta-Analysis of Randomized and Observational Studies: Aspirin Protects from Cardiac Surgery-Associated Acute Kidney Injury.
Topics: Acute Kidney Injury; Aspirin; Cause of Death; Coma; Coronary Artery Bypass; Heart Arrest; Heart Bloc | 2019 |
Repurposing of drugs approved for cardiovascular diseases: Opportunity or mirage?
Topics: Acute Kidney Injury; Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Conv | 2020 |
Prevention of renal dysfunction in postoperative elderly patients.
Topics: Acute Kidney Injury; Aged; Aging; Aspirin; Humans; Kidney; Postoperative Care; Postoperative Complic | 2014 |
Preventable risk factors for acute kidney injury in patients undergoing cardiac surgery.
Topics: Acute Kidney Injury; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Asp | 2012 |
Renal syndromes associated with nonsteroidal antiinflammatory drugs.
Topics: Acute Kidney Injury; Adult; Animals; Anti-Inflammatory Agents; Anuria; Aspirin; Body Water; Electrol | 1984 |
Does aspirin cause acute or chronic renal failure in experimental animals and in humans?
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Anim | 1996 |
Analgesic nephropathy.
Topics: Acute Kidney Injury; Analgesics; Animals; Arthritis, Rheumatoid; Aspirin; Drug Combinations; Female; | 1975 |
The radiology of renal papillary necrosis as seen in analgesic nephropathy.
Topics: Acute Kidney Injury; Adult; Analgesics; Aspirin; Carcinoma, Transitional Cell; Diagnosis, Differenti | 1974 |
Septic shock and disturbances in coagulation.
Topics: Acidosis; Acute Kidney Injury; Aminocaproates; Aspirin; Blood Coagulation Disorders; Blood Coagulati | 1974 |
Treatment of salicylate poisoning.
Topics: Acetaminophen; Acid-Base Equilibrium; Acidosis; Acute Kidney Injury; Alkalosis, Respiratory; Aspirin | 1971 |
3 trials available for aspirin and Acute Kidney Injury
| Article | Year |
|---|---|
Prevention of contrast-induced nephropathy by adequate hydration combined with isosorbide dinitrate for patients with renal insufficiency and congestive heart failure.
Topics: Acute Kidney Injury; Aged; Aspirin; China; Contrast Media; Coronary Angiography; Double-Blind Method | 2019 |
Aspirin and clonidine in non-cardiac surgery: acute kidney injury substudy protocol of the Perioperative Ischaemic Evaluation (POISE) 2 randomised controlled trial.
Topics: Acute Kidney Injury; Adrenergic alpha-2 Receptor Agonists; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
Perioperative aspirin and clonidine and risk of acute kidney injury: a randomized clinical trial.
Topics: Acute Kidney Injury; Administration, Cutaneous; Administration, Oral; Adrenergic alpha-2 Receptor Ag | 2014 |
70 other studies available for aspirin and Acute Kidney Injury
| Article | Year |
|---|---|
ATRvD1 Attenuates Renal Tubulointerstitial Injury Induced by Albumin Overload in Sepsis-Surviving Mice.
Topics: Acute Kidney Injury; Albumins; Animals; Aspirin; Biomarkers; Cytokines; Disease Models, Animal; Doco | 2021 |
Postoperative Acute Kidney Injury With Dual NSAID Use After Outpatient Primary Total Joint Arthroplasty.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Aspiri | 2022 |
Aspirin alleviates cisplatin-induced acute kidney injury through the AMPK-PGC-1α signaling pathway.
Topics: Acute Kidney Injury; AMP-Activated Protein Kinases; Animals; Apoptosis; Aspirin; Cisplatin; Kidney; | 2023 |
Does use of long-term aspirin impact outcomes in patients with acute pancreatitis?
Topics: Acute Disease; Acute Kidney Injury; Adult; Aged; Aspirin; Cysts; Humans; Incidence; Male; Medicare; | 2023 |
Association between preoperative aspirin and acute kidney injury following coronary artery bypass grafting.
Topics: Acute Kidney Injury; Aged; Aspirin; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Plate | 2020 |
Commentary: Teaching an old dog a new trick.
Topics: Acute Kidney Injury; Aspirin; Coronary Artery Bypass; Humans | 2020 |
Concomitant Use of Acetaminophen and Aspirin Increases Risk of Kidney Injury: Analysis of the Japanese Adverse Drug Event Report Database.
Topics: Acetaminophen; Acute Kidney Injury; Adverse Drug Reaction Reporting Systems; Analgesics, Non-Narcoti | 2021 |
Multisystem inflammatory syndrome in an adult with involvement of the skin, lymph nodes, muscle, heart, liver and kidneys.
Topics: Acute Kidney Injury; Adult; Anti-Inflammatory Agents; Aspirin; Asymptomatic Infections; Biomarkers; | 2021 |
Long-term continuous use of proton-pump inhibitors is associated with renal function decline in patients without acute kidney injury.
Topics: Acute Kidney Injury; Aged; Angiotensin Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal | 2021 |
Preoperative aspirin use and acute kidney injury after cardiac surgery: A propensity-score matched observational study.
Topics: Acute Kidney Injury; Aged; Aspirin; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Ca | 2017 |
The use of preoperative aspirin in cardiac surgery: The ruling on the field stands.
Topics: Acute Kidney Injury; Aspirin; Coronary Artery Bypass; Erythrocyte Transfusion; Hemorrhage; Humans; M | 2017 |
Acute Kidney Injury in Kawasaki Disease: Report of 3 Cases From North India and a Brief Review of Literature.
Topics: Acute Kidney Injury; Aspirin; Child; Child, Preschool; Coronary Vessels; Diagnosis, Differential; Ec | 2018 |
Nephrotoxin exposure and acute kidney injury in critically ill children undergoing congenital cardiac surgery.
Topics: Acute Kidney Injury; Adolescent; Aspirin; Cardiac Surgical Procedures; Child; Child, Preschool; Crit | 2018 |
Effects of AT-RvD1 on paraquat-induced acute renal injury in mice.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cyt | 2019 |
Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis).
Topics: Acute Kidney Injury; Aspirin; Diagnosis, Differential; Gastrointestinal Hemorrhage; Humans; Male; Mi | 2013 |
[Profound anemia, hemoglobinuria ... where to stop in the etiological investigation?].
Topics: Acute Kidney Injury; Adolescent; Anemia, Hemolytic; Aspirin; Blackwater Fever; Erythrocyte Transfusi | 2014 |
Aspirin-triggered resolvin D1 down-regulates inflammatory responses and protects against endotoxin-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Blood Ur | 2014 |
Evidence for preoperative aspirin improving major outcomes in patients with chronic kidney disease undergoing cardiac surgery: a cohort study.
Topics: Acute Kidney Injury; Aspirin; Cardiac Surgical Procedures; Glomerular Filtration Rate; Hospital Mort | 2015 |
Prevention of acute kidney injury using vasoactive or antiplatelet treatment: three strikes and out?
Topics: Acute Kidney Injury; Adrenergic alpha-2 Receptor Agonists; Aspirin; Cardiac Surgical Procedures; Clo | 2014 |
Acute kidney injury: Effect of perioperative aspirin and clonidine on AKI.
Topics: Acute Kidney Injury; Adrenergic alpha-2 Receptor Agonists; Aspirin; Clonidine; Female; Humans; Male; | 2015 |
Successful living donor liver transplantation for acute liver failure after acetylsalicylic acid overdose.
Topics: Acute Disease; Acute Kidney Injury; Aspirin; Drug Overdose; Female; Hepatic Encephalopathy; Humans; | 2015 |
Perioperative treatment with aspirin or clonidine and risk of acute kidney injury.
Topics: Acute Kidney Injury; Adrenergic alpha-2 Receptor Agonists; Aspirin; Clonidine; Female; Humans; Male; | 2015 |
Perioperative treatment with aspirin or clonidine and risk of acute kidney injury--reply.
Topics: Acute Kidney Injury; Adrenergic alpha-2 Receptor Agonists; Aspirin; Clonidine; Female; Humans; Male; | 2015 |
Cardiorenal syndromes--recommendations from clinical practice guidelines: the cardiologist's view.
Topics: Acute Disease; Acute Kidney Injury; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhib | 2010 |
A multi-case report of acute renal failure in patients treated with Aggrenox.
Topics: Acute Kidney Injury; Aspirin; Aspirin, Dipyridamole Drug Combination; Creatinine; Dipyridamole; Drug | 2010 |
Determinants of pericardial drainage for cardiac tamponade following cardiac surgery.
Topics: Acute Kidney Injury; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiac Surgical Proced | 2011 |
Ibuprofen or diclofenac is associated with more severe acute kidney injury in nephropathia epidemica.
Topics: Acetaminophen; Acute Kidney Injury; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; C | 2012 |
Caffeic acid phenethyl ester protects kidneys against acetylsalicylic acid toxicity in rats.
Topics: Acute Kidney Injury; Animals; Aspirin; Caffeic Acids; Disease Models, Animal; Dose-Response Relation | 2012 |
Ketorolac-associated renal morbidity: risk factors in cardiac surgical infants.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiac Surgical Procedures; | 2013 |
[Crohn's disease and renal amyloidosis. Acute renal failure].
Topics: Acetaminophen; Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Amyloidosis; Analgesics, Non-Nar | 2002 |
Effects of the anti-ulcer agents ecabet sodium, cimetidine and sucralfate on acetylsalicylic acid-induced gastric mucosal damage deteriorated by renal failure in rats.
Topics: Abietanes; Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; | 2002 |
Acute renal failure in salicylate poisoning.
Topics: Acute Kidney Injury; Aspirin; Humans; Salicylates | 1958 |
THE USE OF THE ARTIFICIAL KIDNEY IN THE COMMUNITY HOSPITAL.
Topics: Acute Kidney Injury; Aspirin; Geriatrics; Hospitals, Community; Kidney; Kidneys, Artificial; Poisoni | 1963 |
ACUTE RENAL FAILURE FOLLOWING ACETOPHENETIDIN INGESTION.
Topics: Acidosis; Acute Kidney Injury; Aspirin; Caffeine; Diabetes Mellitus; Diabetic Ketoacidosis; Diagnosi | 1964 |
ACUTE SALICYLATE POISONING IN ADULTS.
Topics: Acute Kidney Injury; Aspirin; Blood Chemical Analysis; Bronchopneumonia; Coma; Diagnosis, Differenti | 1964 |
NEPHROPATHY ASSOCIATED WITH THE USE OF ANALGESIC MEDICATIONS.
Topics: Acute Kidney Injury; Amobarbital; Analgesics; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Antip | 1965 |
Cardiovascular prophylaxis with aspirin: costs of supply and management of upper gastrointestinal and renal toxicity.
Topics: Acute Kidney Injury; Aged; Aspirin; Cohort Studies; Cost of Illness; Cost-Benefit Analysis; Drug Cos | 2004 |
A Friday afternoon case of apparent anti-glomerular basement nephritis.
Topics: Acetaminophen; Acute Kidney Injury; Analgesics; Animals; Anti-Glomerular Basement Membrane Disease; | 2006 |
[Immunoallergic hemolytic anemia, thrombopenia and acute renal failure induced by aspirin].
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Aspirin; Female; Humans; Immunoglobulin M; Thrombocyt | 1984 |
[Differential therapy of thrombotic-thrombopenic purpura. Administration of fresh plasma versus plasma separation].
Topics: Acute Kidney Injury; Adult; Aspirin; Blood Platelets; Blood Transfusion; Dipyridamole; Erythrocytes; | 1984 |
Altered glomerular eicosanoid biosynthesis in uranyl nitrate-induced acute renal failure.
Topics: Acute Kidney Injury; Animals; Aspirin; Female; Indomethacin; Kidney Glomerulus; Kinetics; Prostaglan | 1984 |
Acute polyuric renal failure after aspirin intoxication.
Topics: Acute Kidney Injury; Adult; Aspirin; Gastric Lavage; Humans; Male; Polyuria | 1983 |
Acute renal failure and piromidic acid.
Topics: Acute Kidney Injury; Aspirin; Biopsy; Drug Therapy, Combination; Female; Humans; Kidney; Middle Aged | 1982 |
Salicylate toxicity following therapeutic doses in young children.
Topics: Acute Kidney Injury; Aspirin; Child, Preschool; Female; Humans; Infant; Male; Pulmonary Edema; Renal | 1981 |
Non-steroidal anti-inflammatory drugs and hospitalization for acute renal failure.
Topics: Acute Kidney Injury; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflamma | 1995 |
Acute anuric renal failure: a complication of combined thrombolytic and antithrombotic therapy.
Topics: Acute Kidney Injury; Angioplasty, Balloon, Coronary; Anuria; Aspirin; Combined Modality Therapy; Dru | 1993 |
Effects of hemoglobin-based oxygen-carrying solutions in anesthetized rats with acute ischemic renal failure.
Topics: Acute Kidney Injury; Animals; Aspirin; Blood Pressure; Glomerular Filtration Rate; Heart Rate; Hemog | 2000 |
The coxibs, selective inhibitors of cyclooxygenase-2.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cycl | 2001 |
In-vitro basophil degranulation in drug-suspected acute renal failure.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Aspirin; Basophils; Drug Hypersensitivity; Huma | 1977 |
Hematologic emergencies in children.
Topics: Acute Disease; Acute Kidney Injury; Adolescent; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Asp | 1978 |
Apparent acute renal failure associated with therapeutic aspirin and ibuprofen administration.
Topics: Acute Kidney Injury; Adult; Aspirin; Female; Humans; Ibuprofen; Kidney | 1979 |
[Comparative studies on lactate dehydrogenase in serum and plasma of rats (author's transl)].
Topics: Acute Kidney Injury; Animals; Aspirin; Blood Platelets; Calcium; Carbon Tetrachloride Poisoning; Fem | 1978 |
Studies on the modification of renal lesions due to aspirin and oxyphenbutazone in the rat and the effects on the kidney of 2:4 dinitrophenol.
Topics: Acetaminophen; Acute Kidney Injury; Animals; Aspirin; Dinitrophenols; Female; Kidney Tubular Necrosi | 1976 |
Analgesic nephropathy.
Topics: Acetaminophen; Acute Kidney Injury; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Co | 1976 |
Analgesic abuse in urological practice.
Topics: Acute Kidney Injury; Adult; Aged; Anemia; Aspirin; Codeine; Female; Humans; Hypertension; Kidney Cal | 1975 |
Acute renal failure following binge drinking and nonsteroidal antiinflammatory drugs.
Topics: Acute Kidney Injury; Adult; Alcoholic Intoxication; Anti-Inflammatory Agents, Non-Steroidal; Aspirin | 1992 |
The possible involvement of platelet activation in endotoxin-induced renal insufficiency in a rabbit model.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Alprostadil; Animals; Aspirin; Endotoxins; Glomerular Fi | 1991 |
Drug-induced haemolysis and renal failure in children with glucose-6-phosphate dehydrogenase deficiency in Afghanistan.
Topics: Acute Kidney Injury; Adolescent; Afghanistan; Antimalarials; Aspirin; Child; Child, Preschool; Chlor | 1990 |
Altered renal and platelet arachidonic acid metabolism in cirrhosis.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Adult; Aged; Arachidonic Acid; Arachidonic Acids; | 1986 |
[Acute hyperkalemia and non-oliguric kidney failure during treatment with indomethacin, allopurinol, nifedipine, hydrochlorothiazide/amiloride, trimethoprim/sulfamethoxazole and acetylsalicylic acid].
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Allopurinol; Amiloride; Aspirin; Drug Combinations; Dr | 1988 |
[Acute interstitial nephritis with renal failure secondary to drugs].
Topics: Acute Disease; Acute Kidney Injury; Adolescent; Adult; Aspirin; Dipyrone; Female; Humans; Male; Midd | 1987 |
Perforated peptic ulcer--a complication in acute salicylate intoxication.
Topics: Acute Disease; Acute Kidney Injury; Aspirin; Cimetidine; Female; Humans; Middle Aged; Peptic Ulcer P | 1987 |
Over-the-counter ibuprofen and acute renal failure.
Topics: Acute Kidney Injury; Adult; Aspirin; Dehydration; Drug Therapy, Combination; Humans; Ibuprofen; Male | 1986 |
Nephrotoxicity from nonsteroidal anti-inflammatory drugs.
Topics: Acute Disease; Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Aspirin; Female; Humans; Hyperka | 1985 |
The short-term effects of aspirin on the rat kidney: further observations.
Topics: Acute Kidney Injury; Animals; Aspirin; Benzopyrenes; Citrates; Drug Tolerance; Enzyme Induction; Fem | 1973 |
The short-term effects of analgesics on the kidney with special reference to acetylsalicylic acid.
Topics: Acetaminophen; Acute Kidney Injury; Administration, Oral; Animals; Aspirin; Caffeine; Dose-Response | 1973 |
Protein binding of drugs in plasma from patients with acute renal failure.
Topics: Acute Kidney Injury; Aged; Aspirin; Blood Proteins; Female; Humans; In Vitro Techniques; Male; Middl | 1973 |
Acute renal failure following analgesic overdose in G6PD deficiency.
Topics: Acute Disease; Acute Kidney Injury; Adult; Anemia, Hemolytic; Anemia, Sideroblastic; Aspirin; Biopsy | 1972 |
Urinary cytology in experimental toxic renal injury.
Topics: Acute Kidney Injury; Animals; Aspirin; Azirines; Chromates; Eosinophils; Histocytochemistry; Kidney | 1970 |
[Acute anuric renal insufficiency with necrosing arteriolitis. Etiologic problems].
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Angioedema; Anuria; Arteritis; Arthritis; Aspirin; Dr | 1968 |