Page last updated: 2024-10-23

aspirin and Active Hyperemia

aspirin has been researched along with Active Hyperemia in 32 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to examine whether aspirin regulates vascular endothelial function following ischemia."9.16Regulation of blood flow by aspirin following muscle ischemia. ( Cameron, SJ; Goulopoulou, S; Kanaley, JA; Weil, BR, 2012)
"Effects of intracoronary aspirin on coronary blood flow and reactive hyperemia were evaluated in closed-chest, anesthetized dogs."7.67Attenuation of reactive hyperemia caused by aspirin in canine coronary artery. ( Aizawa, Y; Miyajima, S; Shibata, A, 1989)
"The purpose of this study was to examine whether aspirin regulates vascular endothelial function following ischemia."5.16Regulation of blood flow by aspirin following muscle ischemia. ( Cameron, SJ; Goulopoulou, S; Kanaley, JA; Weil, BR, 2012)
"The symptom scores for flushing, itching, tingling, and warmth were all significantly reduced by both aspirin regimens (p < ."5.08Effect of two aspirin pretreatment regimens on niacin-induced cutaneous reactions. ( Campbell, JR; Jungnickel, PW; Maloley, PA; Peddicord, TE; Vander Tuin, EL, 1997)
" Flow-dependent dilatation was evaluated before and after L-NMMA or aspirin as the response of the radial artery to an acute increase in flow (reactive hyperemia after a 3-minute cuff wrist occlusion)."3.69Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo. ( Bakkali, EH; Haefeli, WE; Joannides, R; Linder, L; Lüscher, TF; Richard, V; Thuillez, C, 1995)
"Effects of intracoronary aspirin on coronary blood flow and reactive hyperemia were evaluated in closed-chest, anesthetized dogs."3.67Attenuation of reactive hyperemia caused by aspirin in canine coronary artery. ( Aizawa, Y; Miyajima, S; Shibata, A, 1989)
"After short episodes of reactive hyperemia, FMD was abolished by local infusion of the nitric oxide synthesis inhibitor N:(G)monomethyl-L-arginine (5."2.70Heterogenous nature of flow-mediated dilatation in human conduit arteries in vivo: relevance to endothelial dysfunction in hypercholesterolemia. ( Cross, J; Deanfield, JE; Donald, AE; Kharbanda, RK; MacAllister, RJ; Mullen, MJ; Taylor, M; Vallance, P, 2001)
"Ibuprofen was the most efficient agent, inhibiting the total reactive hyperemia by more than 70%, and naproxen was least active, producing about 35% inhibition."2.65Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm. ( Carlsson, I; Wennmalm, A, 1983)
"During reactive hyperemia, plasma endothelin was reduced in normal subjects (-1."1.30Postischemic hyperemia in subjects with lower limbs obstructive arteriopathy: role of PGI2 and endothelin. ( Arosio, E; Lechi, A; Minuz, P; Pancera, P; Ribul, M; Rossi, L, 1997)
" Dose-response experiments performed with 2 to 90 per cent (v/v) zymosan-activated plasma showed a direct correlation between the rate of neutrophil influx and the degree of vascular permeability in blood flow."1.26Vascular responses during acute neutrophilic inflammation. Their relationship to in vivo neutrophil emigration. ( Issekutz, AC, 1981)
"Pretreatment with aspirin plus iridectomy virtually eliminates the elevation of intraocular pressure consequent to paracentesis."1.26Increased pressure after paracentesis of the rabbit eye is completely accounted for by prostaglandin synthesis and release plus pupillary block. ( Al-Ghadyan, A; Mead, A; Sears, M, 1979)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199013 (40.63)18.7374
1990's8 (25.00)18.2507
2000's7 (21.88)29.6817
2010's3 (9.38)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Oncel, S1
Gupta, R1
Wang, Q1
Basson, MD1
Dahmus, JD1
Bruning, RS1
Kenney, WL1
Alexander, LM1
Rousseau, P1
Mahé, G1
Fromy, B1
Ducluzeau, PH1
Saumet, JL1
Abraham, P1
Furuno, T1
Yamasaki, F1
Yokoyama, T1
Sato, K1
Sato, T1
Doi, Y1
Sugiura, T1
Cameron, SJ1
Goulopoulou, S1
Weil, BR1
Kanaley, JA1
COHEN, Y1
LAPRAND, J1
Golay, S1
Haeberli, C1
Delachaux, A2
Liaudet, L2
Kucera, P1
Waeber, B2
Feihl, F2
Gooding, KM1
Hannemann, MM1
Tooke, JE2
Clough, GF1
Shore, AC1
Addor, G1
Dischl, B1
Hayoz, D1
Cragg, A1
Einzig, S1
Rysavy, J1
Castaneda-Zuniga, W1
Borgwardt, B1
Amplatz, K1
Carlsson, I1
Wennmalm, A1
Menys, VC1
Tindall, H1
Feely, M1
Davies, JA1
Issekutz, AC1
Iwata, F1
Zhang, XY1
Leung, FW1
Joannides, R1
Haefeli, WE1
Linder, L1
Richard, V1
Bakkali, EH1
Thuillez, C1
Lüscher, TF1
De Santo, NG1
Calò, L1
Coppola, S1
Anastasio, P1
Cantaro, S1
Favaro, S1
Capasso, G1
Borsatti, A1
Pancera, P1
Minuz, P1
Rossi, L1
Ribul, M1
Arosio, E1
Lechi, A1
Jungnickel, PW1
Maloley, PA1
Vander Tuin, EL1
Peddicord, TE1
Campbell, JR1
Andrieu, S1
Lebret, M1
Maclouf, J1
Bévérelli, F1
Giudicelli, JF1
Berdeaux, A1
Skyrme-Jones, RA1
O'Brien, RC1
Meredith, IT1
Mullen, MJ1
Kharbanda, RK1
Cross, J1
Donald, AE1
Taylor, M1
Vallance, P1
Deanfield, JE1
MacAllister, RJ1
Dulou, R1
Hauret, L1
Renard, JL1
Valle, JN1
Béquet, D1
Felten, D1
Andersson, RG1
Aberg, G1
Brattsand, R1
Ericsson, E1
Lundholm, L1
De Mey, C1
Wellens, D1
Vanhoutte, PM1
Al-Ghadyan, A1
Mead, A1
Sears, M1
Obstbaum, SA1
Podos, SM1
Salem, H1
Dunn, BJ1
Loux, JJ1
Misra, R1
Pandey, H1
Chandra, M2
Agarwal, PK1
Pandeya, SN1
Abignente, E1
Arena, F1
Luraschi, E1
De Caprariss, P1
Marmo, E1
Vitagliano, S1
Donnoli, D1
Miyajima, S1
Aizawa, Y1
Shibata, A1
Bates, ER1
McGillem, MJ1
Beals, TF1
DeBoe, SF1
Mikelson, JK1
Mancini, GB1
Vogel, RA1
Ashley, SW1
Sonnenschein, LA1
Cheung, LY1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Cerebral Vasodilator Responses in Sedentary and Exercise Trained Humans[NCT02653638]Early Phase 180 participants (Actual)Interventional2016-06-30Completed
Efficacy of L-arginine Treatment on Blood Pressure Control Patients With Stage 1 Hypertension[NCT02894723]Phase 440 participants (Anticipated)Interventional2016-09-30Not yet recruiting
The Effect of Type 1 Diabetes on Pan-Arterial Vascular Function and Insulin Sensitivity in Humans[NCT02490124]7 participants (Actual)Observational2014-12-31Completed
Single-centre, Single-blind, Randomized, Controlled, Cross-over Study to Analyze the Influence of Nitric Oxide on Flow Mediated Dilation[NCT03723278]20 participants (Actual)Observational2018-11-14Completed
An Observational Study of Cardiovascular Complications of Carfilzomib Treatment in Clinical Practice[NCT03543579]46 participants (Anticipated)Observational2017-03-23Active, not recruiting
The Impact of Fitness and Mineralocorticoid Receptor Blockade on Vascular Dysfunction in Adults With Type 1 Diabetes[NCT03174288]32 participants (Actual)Interventional2015-08-31Completed
Regulation of Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease: A Mechanistic Approach[NCT01398943]60 participants (Actual)Interventional2010-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Flow-Mediated Dilation (FMD)

Brachial artery FMD induced by reactive hyperemia will be used to assess vascular endothelial function at baseline and several hours after each experimental intervention. (NCT01398943)
Timeframe: Post FMD was taken approximately 110 min after baseline

,
Interventionpercentage of change in FMD (Mean)
PlaceboAOC Treatment
All Controls6.76.9
All COPD Patients3.14.7

Pulse Wave Velocity

A measure of vascular stiffness at baseline and several hours after each experimental intervention. (NCT01398943)
Timeframe: Post PWV was taken approximately 90 min after baseline

,
Interventionm/sec (Mean)
PlaceboAOC Treatment
All Controls1110
All COPD Patients1411

Reviews

1 review available for aspirin and Active Hyperemia

ArticleYear
Physiopathology and pharmacotherapy of occlusive arterial disorders.
    Angiology, 1979, Volume: 30, Issue:7

    Topics: Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Blood Platelets; Blood Viscosity; Cerebrovas

1979

Trials

7 trials available for aspirin and Active Hyperemia

ArticleYear
Oral clopidogrel improves cutaneous microvascular function through EDHF-dependent mechanisms in middle-aged humans.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2013, Aug-15, Volume: 305, Issue:4

    Topics: Administration, Oral; Analysis of Variance; Aspirin; Biological Factors; Blood Flow Velocity; Clopid

2013
Effects of various doses of aspirin on platelet activity and endothelial function.
    Heart and vessels, 2011, Volume: 26, Issue:3

    Topics: Adult; Analysis of Variance; Aspirin; Blood Platelets; Brachial Artery; Dose-Response Relationship,

2011
Regulation of blood flow by aspirin following muscle ischemia.
    European review for medical and pharmacological sciences, 2012, Volume: 16, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Aspirin; Body Composition; Cholest

2012
Maximum skin hyperaemia induced by local heating: possible mechanisms.
    Journal of vascular research, 2006, Volume: 43, Issue:3

    Topics: Aspirin; Cetirizine; Cross-Over Studies; Cyclic GMP; Cyclooxygenase Inhibitors; Double-Blind Method;

2006
Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm.
    Prostaglandins, 1983, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Female; Forearm; Humans; Hyperemi

1983
Effect of two aspirin pretreatment regimens on niacin-induced cutaneous reactions.
    Journal of general internal medicine, 1997, Volume: 12, Issue:10

    Topics: Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Stud

1997
Heterogenous nature of flow-mediated dilatation in human conduit arteries in vivo: relevance to endothelial dysfunction in hypercholesterolemia.
    Circulation research, 2001, Feb-02, Volume: 88, Issue:2

    Topics: Acetylcholine; Adolescent; Adult; Area Under Curve; Aspirin; Autonomic Agents; Blood Flow Velocity;

2001

Other Studies

24 other studies available for aspirin and Active Hyperemia

ArticleYear
ZINC40099027 Promotes Gastric Mucosal Repair in Ongoing Aspirin-Associated Gastric Injury by Activating Focal Adhesion Kinase.
    Cells, 2021, 04-15, Volume: 10, Issue:4

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Creatini

2021
Axon-reflex cutaneous vasodilatation is impaired in type 2 diabetic patients receiving chronic low-dose aspirin.
    Microvascular research, 2009, Volume: 78, Issue:2

    Topics: Acetylcholine; Aspirin; Axons; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Electric

2009
[Study, by means of chromium 51, of bleeding from the digestive tract and gastric hyperemia induced in the rat by the administration of aspirin].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Jun-10, Volume: 157

    Topics: Animals; Aspirin; Blood Volume Determination; Chromium; Chromium Isotopes; Erythrocytes; Gastrointes

1963
Local heating of human skin causes hyperemia without mediation by muscarinic cholinergic receptors or prostanoids.
    Journal of applied physiology (Bethesda, Md. : 1985), 2004, Volume: 97, Issue:5

    Topics: Acetylcholine; Administration, Oral; Adult; Aspirin; Cyclooxygenase Inhibitors; Forearm; Glycopyrrol

2004
A comparative study of reactive hyperemia in human forearm skin and muscle.
    Physiological research, 2008, Volume: 57, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aspirin; Blood Flow Velocity; Cyclooxygenase Inhibitors; Fo

2008
Effect of aspirin on angioplasty-induced vessel wall hyperemia.
    AJR. American journal of roentgenology, 1983, Volume: 140, Issue:6

    Topics: Angioplasty, Balloon; Animals; Arachidonic Acids; Aspirin; Carotid Arteries; Dilatation; Dogs; Hemod

1983
Aspirin, prostacyclin and post-occlusive reactive hyperaemia in man.
    Prostaglandins, leukotrienes, and medicine, 1982, Volume: 9, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Epoprostenol; Humans; Hyperemia; Male

1982
Vascular responses during acute neutrophilic inflammation. Their relationship to in vivo neutrophil emigration.
    Laboratory investigation; a journal of technical methods and pathology, 1981, Volume: 45, Issue:5

    Topics: Animals; Aspirin; Capillary Permeability; Cell Movement; Chemotactic Factors; Escherichia coli; Hype

1981
Aggravation of gastric mucosal lesions in rat stomach by tobacco cigarette smoke.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:5

    Topics: Animals; Aspirin; Ethanol; Gastric Mucosa; Hydrogen; Hyperemia; Male; Nicotiana; Nicotine; Plants, T

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.
    Circulation, 1995, Mar-01, Volume: 91, Issue:5

    Topics: Adult; Arginine; Aspirin; Blood Pressure; Epoprostenol; Female; Forearm; Heart Rate; Humans; Hyperem

1995
Renal prostaglandins and thromboxane A2 lack a functional significance in the genesis of protein-induced glomerular hyperfiltration in human renal disease.
    Nephron, 1993, Volume: 63, Issue:1

    Topics: Adult; Arachidonic Acids; Aspirin; Dietary Proteins; Dinoprost; Dinoprostone; Female; Glomerular Fil

1993
Postischemic hyperemia in subjects with lower limbs obstructive arteriopathy: role of PGI2 and endothelin.
    Angiology, 1997, Volume: 48, Issue:2

    Topics: Aged; Arteriosclerosis; Aspirin; Endothelins; Epoprostenol; Hemodynamics; Humans; Hyperemia; Ilopros

1997
Effects of antiaggregant and antiinflammatory doses of aspirin on coronary hemodynamics and myocardial reactive hyperemia in conscious dogs.
    Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Bradykinin; Coronary Disease; Coronary Vessels; Cycl

1999
Vasodilator prostanoids, but not nitric oxide, may account for skeletal muscle hyperaemia in Type I diabetes mellitus.
    Clinical science (London, England : 1979), 2000, Volume: 99, Issue:5

    Topics: Adult; Area Under Curve; Aspirin; Case-Control Studies; Cyclooxygenase Inhibitors; Diabetes Mellitus

2000
[Pulsating exophtalmos and contralateral carotid-cavernous fistula].
    Revue neurologique, 2002, Volume: 158, Issue:5 Pt 1

    Topics: Aged; Aspirin; Blepharoptosis; Carotid-Cavernous Sinus Fistula; Cavernous Sinus Thrombosis; Conjunct

2002
Studies on the mechanism of flush induced by nicotinic acid.
    Acta pharmacologica et toxicologica, 1977, Volume: 41, Issue:1

    Topics: Animals; Aspirin; Cyclic AMP; Cyclooxygenase Inhibitors; Drug Interactions; Ear, External; Female; G

1977
Increased pressure after paracentesis of the rabbit eye is completely accounted for by prostaglandin synthesis and release plus pupillary block.
    Investigative ophthalmology & visual science, 1979, Volume: 18, Issue:4

    Topics: Animals; Aqueous Humor; Aspirin; Eye Proteins; Hyperemia; Intraocular Pressure; Iris; Prostaglandins

1979
Ocular compression and noncorticosteroidal anti-inflammatory agents.
    American journal of ophthalmology, 1975, Volume: 79, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Conjunctiva; Eye Diseases; Humans; Hyperemia; Indomethac

1975
Conjunctival temperature: a measure of ocular decongestant and anti-inflammatory activity.
    Annals of ophthalmology, 1975, Volume: 7, Issue:6

    Topics: Administration, Oral; Administration, Topical; Animals; Antazoline; Anti-Inflammatory Agents; Aspiri

1975
Effects of commonly used non steroidal anti-inflammatory drugs on gastric mucosa. A clinical, endoscopic and histopathological study.
    The Journal of the Association of Physicians of India, 1990, Volume: 38, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug E

1990
Research on heterocyclic compounds. XXVI. Antiinflammatory and related activities of some 2-phenylimidazo[1,2-b]pyridazines.
    Research communications in chemical pathology and pharmacology, 1990, Volume: 67, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Carrageenan;

1990
Attenuation of reactive hyperemia caused by aspirin in canine coronary artery.
    Angiology, 1989, Volume: 40, Issue:9

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Coronary Circulation; Depression, Chemical; D

1989
Effect of angioplasty-induced endothelial denudation compared with medial injury on regional coronary blood flow.
    Circulation, 1987, Volume: 76, Issue:3

    Topics: Angioplasty, Balloon; Animals; Aspirin; Coronary Circulation; Coronary Vessels; Dogs; Endothelium; F

1987
Focal gastric mucosal blood flow at the site of aspirin-induced ulceration.
    American journal of surgery, 1985, Volume: 149, Issue:1

    Topics: Animals; Aspirin; Dogs; Gastric Mucosa; Hyperemia; Methods; Regional Blood Flow; Stomach; Stomach Ul

1985