Page last updated: 2024-10-22

aspirin and Acid-Base Imbalance

aspirin has been researched along with Acid-Base Imbalance in 8 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Acid-Base Imbalance: Disturbances in the ACID-BASE EQUILIBRIUM of the body.

Research Excerpts

ExcerptRelevanceReference
"A 67-year-old woman and a 75-year-old woman taking carbonic anhydrase inhibitors for therapy of glaucoma and high doses of aspirin for therapy of arthritis developed severe acid-base imbalance and salicylate intoxication."3.66Toxicity of combined therapy with carbonic anhydrase inhibitors and aspirin. ( Anderson, CJ; Kaufman, PL; Sturm, RJ, 1978)
"In the epidemiologic setting of influenza B outbreaks, children who have the acute onset of noninflammatory encephalopathy associated with elevated serum transaminase levels, hypoprothrombinemia, and elevated blood ammonia levels should be considered to have Reye's syndrome."1.26Diagnostic criteria for influenza B-associated Reye's syndrome: clinical vs. pathologic criteria. ( Bregman, D; Corey, L; Gregg, MB; Rubin, RJ, 1977)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Wiederkehr, MR1
Benevides, R1
Santa Ana, CA1
Emmett, M3
Atwood, SJ1
Chalasani, N1
Roman, J1
Jurado, RL1
Narins, RG1
Anderson, CJ1
Kaufman, PL1
Sturm, RJ1
Corey, L1
Rubin, RJ1
Bregman, D1
Gregg, MB1
Cohen, SA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparative Analysis Between Ringer's Lactate vs Acetate Containing Balanced Crystalloid Solution (Plasma Lyte-A) as Cardiopulmonary Bypass Prime[NCT03043131]Phase 360 participants (Anticipated)Interventional2017-02-10Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

8 other studies available for aspirin and Acid-Base Imbalance

ArticleYear
Pseudohyperchloremia and Negative Anion Gap - Think Salicylate!
    The American journal of medicine, 2021, Volume: 134, Issue:9

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Artifacts; Aspirin; Chlorides; Equipment Failu

2021
Approach to the Patient With a Negative Anion Gap.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2016, Volume: 67, Issue:1

    Topics: Acid-Base Imbalance; Aspirin; Female; Humans; Middle Aged; Suicide, Attempted

2016
The laboratory in the diagnosis and management of acetaminophen and salicylate intoxications.
    Pediatric clinics of North America, 1980, Volume: 27, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Acid-Base Imbalance; Aspirin; Child, Preschool; Female; Hepatic Encep

1980
Systemic inflammatory response syndrome caused by chronic salicylate intoxication.
    Southern medical journal, 1996, Volume: 89, Issue:5

    Topics: Acid-Base Imbalance; Adult; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin

1996
Clinical use of the anion gap.
    Medicine, 1977, Volume: 56, Issue:1

    Topics: Acid-Base Imbalance; Acidosis; Acidosis, Renal Tubular; Alkalosis; Alkalosis, Respiratory; Aspirin;

1977
Toxicity of combined therapy with carbonic anhydrase inhibitors and aspirin.
    American journal of ophthalmology, 1978, Volume: 86, Issue:4

    Topics: Acetazolamide; Acid-Base Imbalance; Aged; Arthritis, Rheumatoid; Aspirin; Carbonic Anhydrase Inhibit

1978
Diagnostic criteria for influenza B-associated Reye's syndrome: clinical vs. pathologic criteria.
    Pediatrics, 1977, Volume: 60, Issue:5

    Topics: Acid-Base Imbalance; Ammonia; Aspirin; Humans; Hypoglycemia; Influenza, Human; Liver Function Tests;

1977
Delirious woman with disabling headaches.
    Hospital practice (Office ed.), 1988, Apr-15, Volume: 23, Issue:4

    Topics: Acid-Base Imbalance; Aspirin; Dementia; Female; Headache; Humans; Medication Errors; Middle Aged; Se

1988