Page last updated: 2024-10-23

aspirin and Abnormality, Heart

aspirin has been researched along with Abnormality, Heart in 56 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"To determine the cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib."9.12Cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib. ( Abramson, SB; Chesebro, JH; Farkouh, ME; Fuster, V; Greenberg, JD; Hochman, JS; Jeger, RV; Kirshner, H; Lay, CL; Matchaba, PT; Mellein, B; Ramanathan, K; Ruland, S; Verheugt, FW, 2007)
"The purpose of this study was to determine, on the basis of published reports, whether aspirin use during the first trimester of pregnancy is associated with an increased risk of congenital malformations."8.81Aspirin consumption during the first trimester of pregnancy and congenital anomalies: a meta-analysis. ( Boskovic, R; Costei, A; Koren, G; Kozer, E; Nikfar, S; Nulman, I, 2002)
"Postoperative thrombosis is associated with aspirin unresponsiveness in this patient population."7.80Aspirin unresponsiveness predicts thrombosis in high-risk pediatric patients after cardiac surgery. ( Baird, CW; Emani, S; Emani, SM; Fynn-Thompson, FE; Pigula, FA; Trainor, B; Zurakowski, D, 2014)
"Aspirin is used to prevent thromboembolism in children with heart disease without evidence supporting its efficacy."7.74Aspirin resistance in children with heart disease at risk for thromboembolism: prevalence and possible mechanisms. ( Fixler, DE; Heistein, LC; Journeycake, JM; Lemler, MS; Ramaciotti, C; Scott, WA; Zellers, TM, 2008)
"It has been hypothesized that the ingestion of aspirin by women during pregnancy increases their infants' risk of certain congenital heart defects."7.67The relation of aspirin use during the first trimester of pregnancy to congenital cardiac defects. ( Mitchell, AA; Shapiro, S; Werler, MM, 1989)
"To determine the cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib."5.12Cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib. ( Abramson, SB; Chesebro, JH; Farkouh, ME; Fuster, V; Greenberg, JD; Hochman, JS; Jeger, RV; Kirshner, H; Lay, CL; Matchaba, PT; Mellein, B; Ramanathan, K; Ruland, S; Verheugt, FW, 2007)
" Some are beginning to broaden prenatal screening to include pregnancy complications such as pre-eclampsia that can be prevented using soluble low-dose aspirin treatment started before 16 weeks of gestation."4.93Development of prenatal screening--A historical overview. ( Cuckle, H; Maymon, R, 2016)
"The purpose of this study was to determine, on the basis of published reports, whether aspirin use during the first trimester of pregnancy is associated with an increased risk of congenital malformations."4.81Aspirin consumption during the first trimester of pregnancy and congenital anomalies: a meta-analysis. ( Boskovic, R; Costei, A; Koren, G; Kozer, E; Nikfar, S; Nulman, I, 2002)
" Bleeding rates were high in both groups; however, bleeding was more frequent in the warfarin group."4.02Long-term outcomes of warfarin versus aspirin after Fontan surgery. ( Attard, C; Briody, J; Cordina, R; d'Udekem, Y; Hassan, EB; Ignjatovic, V; Mackay, MT; Monagle, PT; Rice, K; Simm, P, 2021)
" Additionally, he had undergone an aortic root dilatation and aortic valve replacement at the age of 10 because of progression of aortic and supra-aortic stenosis and had received chronic anticoagulation and antiplatelet therapy with warfarin and aspirin, respectively."4.02Spontaneous Spinal Epidural Hematoma in an Adult Patient with Complex Congenital Heart Disease. ( Ifuku, T; Nishiguchi, T, 2021)
"There are few data to guide aspirin therapy to prevent shunt thrombosis in infants."3.85Platelet Inhibition in Shunted Infants on Aspirin at Short and Midterm Follow-Up. ( Bailly, DK; Burch, PT; Clawson, JR; Johnson, JT; LuAnn Minich, L; Sheng, X; Truong, DT; Witte, MK, 2017)
"To characterize platelet function and responsiveness to aspirin in relation to thrombogenesis, systemic inflammation, and markers of endothelial function in adults with Fontan circulation (FC)."3.81Aspirin resistance in adult patients after Fontan surgery. ( Chłopicki, S; Komar, M; Musiałek, P; Olszowska, M; Pajak, J; Podolec, J; Podolec, P; Rubis, P; Sitek, B; Tomkiewicz-Pajak, L; Wojcik, T, 2015)
" Centers with best outcomes implement aspirin earlier in their postoperative shunt thrombosis prophylaxis regimen."3.80Defining the best practice patterns for the neonatal systemic-to-pulmonary artery shunt procedure. ( Brar, A; Eghtesady, P; Hall, M; Heidari-Bateni, G; Norouzi, S, 2014)
"Postoperative thrombosis is associated with aspirin unresponsiveness in this patient population."3.80Aspirin unresponsiveness predicts thrombosis in high-risk pediatric patients after cardiac surgery. ( Baird, CW; Emani, S; Emani, SM; Fynn-Thompson, FE; Pigula, FA; Trainor, B; Zurakowski, D, 2014)
"Aspirin is often used to prevent thrombosis in pediatric cardiac surgery."3.76Aspirin resistance following pediatric cardiac surgery. ( Alfieris, GM; Blumberg, N; Cholette, JM; Lerner, NB; Mamikonian, L, 2010)
"Aspirin is used to prevent thromboembolism in children with heart disease without evidence supporting its efficacy."3.74Aspirin resistance in children with heart disease at risk for thromboembolism: prevalence and possible mechanisms. ( Fixler, DE; Heistein, LC; Journeycake, JM; Lemler, MS; Ramaciotti, C; Scott, WA; Zellers, TM, 2008)
"It has been hypothesized that the ingestion of aspirin by women during pregnancy increases their infants' risk of certain congenital heart defects."3.67The relation of aspirin use during the first trimester of pregnancy to congenital cardiac defects. ( Mitchell, AA; Shapiro, S; Werler, MM, 1989)
"Testing platelet function makes clopidogrel dosing safer, and simplifies therapy adjustments in long-term treatment."2.77Prophylactic use of clopidogrel in paediatric cardiac patients. ( Grohmann, J; Hanke, CA; Nakamura, L; Stiller, B; Zieger, B, 2012)
" Inadequate initial dosing appears to be the primary reason for aspirin resistance."1.72Aspirin resistance in infants with shunt-dependent congenital heart disease. ( Cooper, DS; Henry, B; Koh, W; Nebbia, A; Rodts, M; Sawyer, J, 2022)
"Aspirin resistance was defined as platelet inhibition below 50%."1.51Prevalence of aspirin resistance by thromboelastography plus platelet mapping in children with CHD: a single-centre experience. ( Bartakian, S; Berganza, FM; Brownlee, J; Egbe, AC; Gonzalez de Alba, C, 2019)
" A randomised trial is needed to determine appropriate acetylsalicylic acid dosing in infants with modified Blalock-Taussig."1.51High acetylsalicylic acid dosing in infants after modified Blalock-Taussig shunt. ( Allen, J; Boston, US; Cowan, KM; Jones, T; Joshi, AD; Knott-Craig, CJ; Kumar, STK; Nouer, SS; Saini, A; Shah, SH; Wayne Gatewood, C, 2019)
" Unlike general toxicity data, their prenatal toxic effects were not extensively studied before."1.33Comparison of developmental toxicity of selective and non-selective cyclooxygenase-2 inhibitors in CRL:(WI)WUBR Wistar rats--DFU and piroxicam study. ( Burdan, F, 2005)
"Aspirin was discontinued on the personal decision of individual physicians."1.30Reduced frequency of occlusion of aorto-pulmonary shunts in infants receiving aspirin. ( Bürsch, J; Motz, R; Ruschewski, W; Wessel, A, 1999)
" Optimum drug or combination of drugs and dosage are still controversial."1.26[Inhibition of platelet function in pediatric medicine (author's transl)]. ( Schmidt, B, 1982)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199013 (23.21)18.7374
1990's7 (12.50)18.2507
2000's10 (17.86)29.6817
2010's22 (39.29)24.3611
2020's4 (7.14)2.80

Authors

AuthorsStudies
Song, QQ1
Zhu, LH1
Chen, OY1
Xiao, ZR1
Chen, Z1
Xiao, YB1
Meng, JC1
Zuo, C1
Latour, JM1
Attard, C3
Monagle, PT1
d'Udekem, Y3
Mackay, MT1
Briody, J1
Cordina, R1
Hassan, EB1
Simm, P1
Rice, K1
Ignjatovic, V2
Ifuku, T1
Nishiguchi, T1
Koh, W1
Rodts, M1
Nebbia, A1
Sawyer, J1
Henry, B1
Cooper, DS1
Zhou, C1
Guo, X1
Cui, Q1
Liu, X1
Su, G1
Zhang, J1
Huang, J1
Monagle, P1
Uber, AM1
Montez-Rath, ME1
Kwiatkowski, DM1
Krawczeski, CD1
Sutherland, SM1
Berganza, FM1
Gonzalez de Alba, C1
Egbe, AC1
Bartakian, S1
Brownlee, J1
Saini, A1
Joshi, AD1
Cowan, KM1
Wayne Gatewood, C1
Kumar, STK1
Allen, J1
Shah, SH1
Nouer, SS1
Jones, T1
Knott-Craig, CJ1
Boston, US1
Potter, BJ1
Leong-Sit, P1
Fernandes, SM1
Feifer, A1
Mayer, JE1
Triedman, JK1
Walsh, EP1
Landzberg, MJ1
Khairy, P1
Seckeler, MD1
D'Souza, MD1
Gangemi, JJ1
Hoyer, AW1
Jayakumar, KA1
Alizade, E1
Çağan Efe, S1
Kutlutürk, I1
Fidan, S1
Avcı, A1
Metin Esen, A1
Heidari-Bateni, G1
Norouzi, S1
Hall, M1
Brar, A1
Eghtesady, P1
Emani, S1
Trainor, B1
Zurakowski, D1
Baird, CW1
Fynn-Thompson, FE1
Pigula, FA1
Emani, SM1
Wilson, SR1
Kronzon, I1
Machnicki, SC1
Ruiz, CE1
Tomkiewicz-Pajak, L1
Wojcik, T1
Chłopicki, S1
Olszowska, M1
Pajak, J1
Podolec, J1
Sitek, B1
Musiałek, P1
Rubis, P1
Komar, M1
Podolec, P1
Cuckle, H1
Maymon, R1
Iyengar, AJ1
Winlaw, DS1
Galati, JC1
Wheaton, GR1
Gentles, TL1
Grigg, LE1
Justo, RN1
Radford, DJ1
Weintraub, RG1
Bullock, A1
Sholler, GS1
Celermajer, DS1
Truong, DT1
Johnson, JT1
Bailly, DK1
Clawson, JR1
Sheng, X1
Burch, PT1
Witte, MK1
LuAnn Minich, L1
Protopapas, AD1
Athanasiou, T1
Gordon, BM1
Moore, JW1
Fouladkou, F1
Lu, C1
Jiang, C1
Zhou, L1
She, Y1
Walls, JR1
Kawabe, H1
Brose, N1
Henkelman, RM1
Huang, A1
Bruneau, BG1
Rotin, D1
Ganigara, M1
Prabhu, A1
Varghese, R1
Pavithran, S1
Valliatu, J1
Nair, RS1
Cholette, JM1
Mamikonian, L1
Alfieris, GM1
Blumberg, N1
Lerner, NB1
Hanke, CA1
Stiller, B1
Nakamura, L1
Grohmann, J1
Zieger, B1
Gokce, M1
Altan, I1
Unal, S1
Kuskonmaz, B1
Aytac, S1
Cetin, M1
Tuncer, M1
Gumruk, F1
Gurgey, A1
Romlin, BS1
Wåhlander, H1
Strömvall-Larsson, E1
Synnergren, M1
Baghaei, F1
Jeppsson, A1
Kozer, E1
Nikfar, S1
Costei, A1
Boskovic, R1
Nulman, I1
Koren, G1
Sideris, EB1
Luo, XJ1
Yan, J1
Wu, QY1
Yang, KM1
Xu, JP1
Liu, YL1
Burdan, F1
Barker, PC1
Nowak, C1
King, K1
Mosca, RS1
Bove, EL1
Goldberg, CS1
Farkouh, ME1
Greenberg, JD1
Jeger, RV1
Ramanathan, K1
Verheugt, FW1
Chesebro, JH2
Kirshner, H1
Hochman, JS1
Lay, CL1
Ruland, S1
Mellein, B1
Matchaba, PT1
Fuster, V2
Abramson, SB1
Li, JS1
Yow, E1
Berezny, KY1
Rhodes, JF1
Bokesch, PM1
Charpie, JR1
Forbus, GA1
Mahony, L1
Boshkov, L1
Lambert, V1
Bonnet, D1
Michel-Behnke, I1
Graham, TP1
Takahashi, M1
Jaggers, J1
Califf, RM1
Rakhit, A1
Fontecave, S1
Sanders, SP1
Heistein, LC1
Scott, WA1
Zellers, TM1
Fixler, DE1
Ramaciotti, C1
Journeycake, JM1
Lemler, MS1
Agarwal, KC1
Wahner, HW1
Dewanjee, MK1
Puga, FJ1
Danielson, GK1
Feldt, RH1
Willoughby, ML1
Schmidt, B2
Fiane, AE1
Seem, E1
Geiran, O1
Lindberg, HL1
Malouf, JF1
Alam, S1
Gharzeddine, W1
Stefadouros, MA1
Centazzo, S1
Montigny, M1
Davignon, A1
Chartrand, C1
Fournier, A1
Marchand, T1
Ammash, N1
Warnes, CA1
Motz, R1
Wessel, A1
Ruschewski, W1
Bürsch, J1
Rudolph, AM2
Heymann, MA2
Sutor, H1
Lorenz, H1
Tikkanen, J1
Heinonen, OP1
Raub, W1
Werler, MM1
Mitchell, AA1
Shapiro, S1
Sherman, DG1
Dyken, ML1
Fisher, M1
Harrison, MJ1
Hart, RG1
Zierler, S1
Rothman, KJ1
Palmer, AK2
Goldschmidt, B1
Sorland, SJ1
Bjornstad, PG1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Aspirin for the Prevention of Preeclampsia in Women With Stage 1 Hypertension: A Pilot Study[NCT04908982]Phase 460 participants (Anticipated)Interventional2021-05-28Recruiting
Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)[NCT02409680]11,976 participants (Actual)Interventional2016-03-23Completed
Antiplatelet Activity of Aspirin in Infants After Aortopulmonary and Cavopulmonary Shunts[NCT01656993]25 participants (Actual)Observational2012-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Fetal Outcome 1 - Incidence of Early Preterm Delivery (<34 Weeks)

- Early preterm delivery (<34 weeks) (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm189
Placebo Arm230

Fetal Outcome 2 - Incidence of Actual Birth Weight <2500g

- Birth weight <2500g (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm1078
Placebo Arm1153

Fetal Outcome 3 - Incidence of Actual Birth Weight <1500g

- Birth weight <1500g (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm78
Placebo Arm101

Fetal Outcome 4 - Incidence of Fetal Loss

- Incidence of Fetal Loss (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm303
Placebo Arm353

Fetal Outcome 5 - Incidence of Spontaneous Abortion

- Incidence of Spontaneous Abortion (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm134
Placebo Arm152

Fetal Outcome 6 - Incidence of All Stillbirth

- Incidence of All stillbirth (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm141
Placebo Arm166

Fetal Outcome 7 - Incidence of Medical Termination of Pregnancy

- Incidence of Medical Termination of Pregnancy (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm42
Placebo Arm30

Incidence of Hypertensive Disorders of Pregnancy

- Hypertensive disorders of pregnancy is defined by the characterization of evidence of a hypertensive disorder, including either preeclampsia or eclampsia occurring during the pregnancy. (NCT02409680)
Timeframe: Evidence of hypertensive disorder during the pregnancy (prior to delivery/birth)

InterventionParticipants (Count of Participants)
Intervention Arm352
Placebo Arm325

Incidence of Perinatal Mortality

- Incidence of Perinatal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm264
Placebo Arm309

Incidence of Preterm Birth

The primary outcome of this study is incidence of preterm birth, which will be defined as delivery at or after 20 0/7 weeks and prior to 37 0/7 weeks. This will be determined based on actual date of delivery in comparison to the projected estimated due date (EDD), independent of whether or not the preterm delivery is indicated or spontaneous. (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm668
Placebo Arm754

Incidence of Small for Gestational Age (SGA)

- Small for gestational age (SGA) as defined by the INTERGROWTH-21st standard (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm1506
Placebo Arm1564

Maternal Outcome 1 - Incidence of Vaginal Bleeding

- Vaginal bleeding (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm214
Placebo Arm246

Maternal Outcome 2 - Incidence of Antepartum Hemorrhage

- Antepartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm26
Placebo Arm25

Maternal Outcome 3 - Incidence of Postpartum Hemorrhage

- Postpartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm54
Placebo Arm43

Maternal Outcome 4 - Incidence of Maternal Mortality

- Incidence of Maternal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm9
Placebo Arm12

Maternal Outcome 5 - Incidence of Late Abortion

- Incidence of Late Abortion (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm23
Placebo Arm30

Maternal Outcome 6 - Change in Maternal Hemoglobin

Hemoglobin < 7.0 gm/dl at 26-30 weeks gestation or a drop of 3.5+ gm/dl from screening to 26-30 weeks gestation (NCT02409680)
Timeframe: At enrollment, 4 weeks post enrollment, and 26-30 weeks GA.

InterventionParticipants (Count of Participants)
Intervention Arm290
Placebo Arm333

Maternal Outcome 7 - Incidence of Preterm, Preeclampsia

Early preterm delivery (<34 weeks) and hypertensive disorders (i.e.: preeclampsia) (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm8
Placebo Arm21

Reviews

6 reviews available for aspirin and Abnormality, Heart

ArticleYear
Pathophysiology of thrombosis and anticoagulation post Fontan surgery.
    Thrombosis research, 2018, Volume: 172

    Topics: Anticoagulants; Aspirin; Fibrinolytic Agents; Fontan Procedure; Heart Defects, Congenital; Humans; T

2018
Development of prenatal screening--A historical overview.
    Seminars in perinatology, 2016, Volume: 40, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Cell-Free System; DNA; Down Syndrome;

2016
Contegra conduit for reconstruction of the right ventricular outflow tract: a review of published early and mid-time results.
    Journal of cardiothoracic surgery, 2008, Nov-18, Volume: 3

    Topics: Aspirin; Bioprosthesis; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Fibrinolytic

2008
Aspirin consumption during the first trimester of pregnancy and congenital anomalies: a meta-analysis.
    American journal of obstetrics and gynecology, 2002, Volume: 187, Issue:6

    Topics: Abnormalities, Drug-Induced; Aspirin; Case-Control Studies; Cohort Studies; Congenital Abnormalities

2002
Aspirin consumption during the first trimester of pregnancy and congenital anomalies: a meta-analysis.
    American journal of obstetrics and gynecology, 2002, Volume: 187, Issue:6

    Topics: Abnormalities, Drug-Induced; Aspirin; Case-Control Studies; Cohort Studies; Congenital Abnormalities

2002
Aspirin consumption during the first trimester of pregnancy and congenital anomalies: a meta-analysis.
    American journal of obstetrics and gynecology, 2002, Volume: 187, Issue:6

    Topics: Abnormalities, Drug-Induced; Aspirin; Case-Control Studies; Cohort Studies; Congenital Abnormalities

2002
Aspirin consumption during the first trimester of pregnancy and congenital anomalies: a meta-analysis.
    American journal of obstetrics and gynecology, 2002, Volume: 187, Issue:6

    Topics: Abnormalities, Drug-Induced; Aspirin; Case-Control Studies; Cohort Studies; Congenital Abnormalities

2002
[Congenital and acquired thrombocyte function disorders].
    Kinderarztliche Praxis, 1980, Volume: 48, Issue:7

    Topics: Aspirin; Blood Platelet Disorders; Dipyridamole; Fibrin Fibrinogen Degradation Products; Heart Defec

1980
Cerebral embolism.
    Chest, 1986, Volume: 89, Issue:2 Suppl

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Calcinosis; Cardiomyopathy, Hypertrophic; Clinical Tri

1986

Trials

4 trials available for aspirin and Abnormality, Heart

ArticleYear
Prophylactic use of clopidogrel in paediatric cardiac patients.
    Klinische Padiatrie, 2012, Volume: 224, Issue:3

    Topics: Aspirin; Child; Child, Preschool; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combi

2012
Cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib.
    Annals of the rheumatic diseases, 2007, Volume: 66, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cyclooxygenase 2 In

2007
Cerebral embolism.
    Chest, 1986, Volume: 89, Issue:2 Suppl

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Calcinosis; Cardiomyopathy, Hypertrophic; Clinical Tri

1986
The effect of acetylsalicylic acid on platelet function in cyanotic congenital heart disease.
    Acta paediatrica Scandinavica, 1974, Volume: 63, Issue:6

    Topics: Adolescent; Aspirin; Blood Cell Count; Blood Coagulation; Blood Platelets; Child; Child, Preschool;

1974

Other Studies

47 other studies available for aspirin and Abnormality, Heart

ArticleYear
Compliance with aspirin in paediatric CHD post-percutaneous transcatheter occlusion: a cross-sectional study.
    Cardiology in the young, 2020, Volume: 30, Issue:10

    Topics: Aspirin; Caregivers; Child; Cross-Sectional Studies; Health Knowledge, Attitudes, Practice; Heart De

2020
Long-term outcomes of warfarin versus aspirin after Fontan surgery.
    The Journal of thoracic and cardiovascular surgery, 2021, Volume: 162, Issue:4

    Topics: Anticoagulants; Aspirin; Australia; Bone Density; Chemoprevention; Child; Cohort Studies; Female; Fo

2021
Spontaneous Spinal Epidural Hematoma in an Adult Patient with Complex Congenital Heart Disease.
    International heart journal, 2021, Jul-30, Volume: 62, Issue:4

    Topics: Adult; Anticoagulants; Aortic Valve Stenosis; Aspirin; Heart Defects, Congenital; Heart Septal Defec

2021
Aspirin resistance in infants with shunt-dependent congenital heart disease.
    Cardiology in the young, 2022, Volume: 32, Issue:5

    Topics: Aspirin; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Thrombosis

2022
Sildenafil improves the function of endothelial cells in patients suffering from congenital heart disease with pulmonary hypertension.
    Die Pharmazie, 2016, Oct-01, Volume: 71, Issue:10

    Topics: Adiponectin; Animals; Aspirin; Endothelial Cells; Endothelin-1; Enzyme-Linked Immunosorbent Assay; H

2016
Nephrotoxin exposure and acute kidney injury in critically ill children undergoing congenital cardiac surgery.
    Pediatric nephrology (Berlin, Germany), 2018, Volume: 33, Issue:11

    Topics: Acute Kidney Injury; Adolescent; Aspirin; Cardiac Surgical Procedures; Child; Child, Preschool; Crit

2018
Prevalence of aspirin resistance by thromboelastography plus platelet mapping in children with CHD: a single-centre experience.
    Cardiology in the young, 2019, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Aspirin; Cardiac Surgical Procedures; Child; Child, Preschool; Drug Resistance; F

2019
High acetylsalicylic acid dosing in infants after modified Blalock-Taussig shunt.
    Cardiology in the young, 2019, Volume: 29, Issue:3

    Topics: Administration, Oral; Aspirin; Blalock-Taussig Procedure; Computed Tomography Angiography; Dose-Resp

2019
Effect of aspirin and warfarin therapy on thromboembolic events in patients with univentricular hearts and Fontan palliation.
    International journal of cardiology, 2013, Oct-09, Volume: 168, Issue:4

    Topics: Adolescent; Aspirin; Child; Child, Preschool; Cohort Studies; Female; Follow-Up Studies; Fontan Proc

2013
Thrombotic occlusion of extracardiac conduit 4 months after Fontan surgery.
    Texas Heart Institute journal, 2013, Volume: 40, Issue:3

    Topics: Aspirin; Child, Preschool; Drug Substitution; Drug Therapy, Combination; Fibrinolytic Agents; Fontan

2013
Occlusion of the retinal artery occlusion by undiagnosed accessory mitral valve tissue.
    Herz, 2014, Volume: 39, Issue:5

    Topics: Aspirin; Diagnosis, Differential; Echocardiography, Transesophageal; Embolism; Fluorescein Angiograp

2014
Defining the best practice patterns for the neonatal systemic-to-pulmonary artery shunt procedure.
    The Journal of thoracic and cardiovascular surgery, 2014, Volume: 147, Issue:3

    Topics: Aspirin; Bayes Theorem; Benchmarking; Cardiac Surgical Procedures; Chi-Square Distribution; Drug Adm

2014
Aspirin unresponsiveness predicts thrombosis in high-risk pediatric patients after cardiac surgery.
    The Journal of thoracic and cardiovascular surgery, 2014, Volume: 148, Issue:3

    Topics: Age Factors; Aspirin; Boston; Cardiac Surgical Procedures; Child, Preschool; Drug Resistance; Female

2014
A constrained heart: a case of sudden onset unrelenting chest pain.
    Circulation, 2014, Oct-28, Volume: 130, Issue:18

    Topics: Analgesics, Opioid; Aspirin; Chest Pain; Clopidogrel; Coronary Angiography; Drug Therapy, Combinatio

2014
Aspirin resistance in adult patients after Fontan surgery.
    International journal of cardiology, 2015, Feb-15, Volume: 181

    Topics: Adult; Aspirin; CD40 Antigens; Drug Resistance; Endothelium, Vascular; Female; Fontan Procedure; Hea

2015
No difference between aspirin and warfarin after extracardiac Fontan in a propensity score analysis of 475 patients.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2016, Volume: 50, Issue:5

    Topics: Anticoagulants; Aspirin; Australia; Female; Fontan Procedure; Heart Defects, Congenital; Hemorrhage;

2016
Platelet Inhibition in Shunted Infants on Aspirin at Short and Midterm Follow-Up.
    Pediatric cardiology, 2017, Volume: 38, Issue:2

    Topics: Aspirin; Cardiac Surgical Procedures; Female; Follow-Up Studies; Heart Defects, Congenital; Hemorrha

2017
Nickel for your thoughts: Survey of the Congenital Cardiovascular Interventional Study Consortium (CCISC) for nickel allergy.
    The Journal of invasive cardiology, 2009, Volume: 21, Issue:7

    Topics: Alloys; Aspirin; Cardiac Catheterization; Data Collection; Drug Hypersensitivity; Female; Heart Defe

2009
The ubiquitin ligase Nedd4-1 is required for heart development and is a suppressor of thrombospondin-1.
    The Journal of biological chemistry, 2010, Feb-26, Volume: 285, Issue:9

    Topics: Animals; Aspirin; Endosomal Sorting Complexes Required for Transport; Female; Fibroblasts; Heart; He

2010
Extracardiac Fontan operation after late bidirectional Glenn shunt.
    Asian cardiovascular & thoracic annals, 2010, Volume: 18, Issue:3

    Topics: Adolescent; Anticoagulants; Aspirin; Blood Pressure; Chest Tubes; Child; Child, Preschool; Drainage;

2010
Aspirin resistance following pediatric cardiac surgery.
    Thrombosis research, 2010, Volume: 126, Issue:3

    Topics: Administration, Oral; Administration, Rectal; Aspirin; Biomarkers; C-Reactive Protein; Cardiac Surgi

2010
The devastating consequences of thrombosis of systemico pulmonary shunts and the blind administration of aspirin.
    Thrombosis research, 2010, Volume: 126, Issue:3

    Topics: Aspirin; Cardiac Surgical Procedures; Drug Resistance; Evidence-Based Medicine; Fibrinolytic Agents;

2010
Recurrent pediatric thrombosis: the effect of underlying and/or coexisting factors.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2012, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Anticoagulants; Aspirin; Child; Child, Preschool; Chronic Disease; Factor VIII; F

2012
Monitoring of acetyl salicylic acid-induced platelet inhibition with impedance aggregometry in children with systemic-to-pulmonary shunts.
    Cardiology in the young, 2013, Volume: 23, Issue:2

    Topics: Aspirin; Blalock-Taussig Procedure; Double Outlet Right Ventricle; Electric Impedance; Female; Heart

2013
TREATMENT of acute rheumatic fever in children a co-operative clinical trial of A.C.T.H., cortisone, and aspirin; a joint report by the Rheumatic Fever Working Party of the Medical Research Council of Great Britain and the Subcommittee of Principal Invest
    British medical journal, 1955, Mar-05, Volume: 1, Issue:4913

    Topics: Adrenocorticotropic Hormone; American Heart Association; Aspirin; Biomedical Research; Child; Cortis

1955
Advances in transcatheter patch occlusion of heart defects.
    Journal of interventional cardiology, 2003, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Aspirin; Balloon Occlusion; Cardiac Catheterization; Catheters, Indwelling; Child

2003
Clinical application of bidirectional Glenn shunt with off-pump technique.
    Asian cardiovascular & thoracic annals, 2004, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Arteriovenous Shunt, Surgical; Aspirin; Blood Pressure; Cardiopulmonary Bypass; C

2004
Comparison of developmental toxicity of selective and non-selective cyclooxygenase-2 inhibitors in CRL:(WI)WUBR Wistar rats--DFU and piroxicam study.
    Toxicology, 2005, Jul-01, Volume: 211, Issue:1-2

    Topics: Abdominal Wall; Abnormalities, Drug-Induced; Alanine Transaminase; Animals; Aspartate Aminotransfera

2005
Risk factors for cerebrovascular events following fontan palliation in patients with a functional single ventricle.
    The American journal of cardiology, 2005, Aug-15, Volume: 96, Issue:4

    Topics: Aspirin; Cardiac Catheterization; Child, Preschool; Echocardiography; Female; Follow-Up Studies; Fon

2005
Clinical outcomes of palliative surgery including a systemic-to-pulmonary artery shunt in infants with cyanotic congenital heart disease: does aspirin make a difference?
    Circulation, 2007, Jul-17, Volume: 116, Issue:3

    Topics: Aspirin; Cardiac Surgical Procedures; Heart Defects, Congenital; Humans; Infant; Palliative Care; Pr

2007
Aspirin resistance in children with heart disease at risk for thromboembolism: prevalence and possible mechanisms.
    Pediatric cardiology, 2008, Volume: 29, Issue:2

    Topics: Adolescent; Aspirin; Blood Platelets; Child; Child, Preschool; Dose-Response Relationship, Drug; Dru

2008
Imaging of platelets in right-sided extracardiac conduits in humans.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1982, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Child; Dipyridamole; Evaluatio

1982
[Inhibition of platelet function in pediatric medicine (author's transl)].
    Klinische Padiatrie, 1982, Volume: 194, Issue:2

    Topics: Age Factors; Aspirin; Child; Dipyridamole; Glomerulonephritis; Graft Rejection; Heart Defects, Conge

1982
CarboMedics valve in congenital heart disease. Midterm follow-up study of 14 patients.
    Scandinavian journal of thoracic and cardiovascular surgery, 1994, Volume: 28, Issue:3-4

    Topics: Aortic Valve; Aspirin; Child; Dipyridamole; Female; Follow-Up Studies; Heart Defects, Congenital; He

1994
The role of anticoagulation in the development of pericardial effusion and late tamponade after cardiac surgery.
    European heart journal, 1993, Volume: 14, Issue:11

    Topics: Adult; Anticoagulants; Aspirin; Cardiac Surgical Procedures; Cardiac Tamponade; Coronary Artery Bypa

1993
Use of acetylsalicylic acid to improve patency of subclavian to pulmonary artery Gore-Tex shunts.
    The Canadian journal of cardiology, 1993, Volume: 9, Issue:3

    Topics: Aspirin; Blood Vessel Prosthesis; Female; Heart Defects, Congenital; Humans; Infant; Male; Polytetra

1993
Cerebrovascular events in adult patients with cyanotic congenital heart disease.
    Journal of the American College of Cardiology, 1996, Volume: 28, Issue:3

    Topics: Adult; Aged; Anemia, Iron-Deficiency; Anticoagulants; Aspirin; Atrial Fibrillation; Cerebrovascular

1996
Reduced frequency of occlusion of aorto-pulmonary shunts in infants receiving aspirin.
    Cardiology in the young, 1999, Volume: 9, Issue:5

    Topics: Aorta; Arteriovenous Shunt, Surgical; Aspirin; Case-Control Studies; Female; Graft Occlusion, Vascul

1999
Medical treatment of the ductus arteriosus.
    Hospital practice, 1977, Volume: 12, Issue:2

    Topics: Animals; Aspirin; Coronary Circulation; Ductus Arteriosus; Ductus Arteriosus, Patent; Fetal Heart; F

1977
Effects of prostaglandins and blockers of prostaglandin synthesis on the ductus arteriosus: animal and human studies.
    Advances in prostaglandin and thromboxane research, 1978, Volume: 4

    Topics: Animals; Aspirin; Ductus Arteriosus; Fetus; Heart Defects, Congenital; Humans; Infant, Newborn; Musc

1978
[Hamostasiological changes induced by platelet-aggregation-inhibitors, tested in children with congenital heart disease (in vitro and in vitro examinations) (author's transl)].
    Klinische Padiatrie, 1976, Volume: 188, Issue:5

    Topics: Adolescent; Aspirin; Child; Child, Preschool; Cyanosis; Dipyridamole; Heart Defects, Congenital; Hem

1976
Maternal hyperthermia during pregnancy and cardiovascular malformations in the offspring.
    European journal of epidemiology, 1991, Volume: 7, Issue:6

    Topics: Aspirin; Data Collection; Female; Fever; Finland; Heart Defects, Congenital; Humans; Infant, Newborn

1991
From the National Institutes of Health.
    JAMA, 1990, Mar-02, Volume: 263, Issue:9

    Topics: Aspirin; Breast Neoplasms; Female; Fetal Diseases; Heart Defects, Congenital; Humans; Immunotherapy;

1990
The relation of aspirin use during the first trimester of pregnancy to congenital cardiac defects.
    The New England journal of medicine, 1989, Dec-14, Volume: 321, Issue:24

    Topics: Abnormalities, Drug-Induced; Aortic Coarctation; Aortic Valve Stenosis; Aspirin; Case-Control Studie

1989
Congenital heart disease in relation to maternal use of Bendectin and other drugs in early pregnancy.
    The New England journal of medicine, 1985, Aug-08, Volume: 313, Issue:6

    Topics: Acetaminophen; Adult; Anti-Bacterial Agents; Antiemetics; Aspirin; Dicyclomine; Doxylamine; Drug Com

1985
Problems associated with the screening of drugs for possible teratogenic activity.
    Experimental embryology and teratology, 1974, Volume: 1, Issue:0

    Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Aspirin; Dose-Response Rela

1974
Sporadic malformations in laboratory animals and their influence on drug testing.
    Advances in experimental medicine and biology, 1972, Volume: 27

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Laboratory; Aspirin; Bone and Bones; Congenital Abnor

1972