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aspartic acid and Tremor

aspartic acid has been researched along with Tremor in 13 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
" tremor, myoclonus and convulsions, successively appear, have been studied in fed and fasted rats with and without pretreatment with 2-amino-7-phosphonoheptanoic acid (180 mg/kg)."7.67The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats. ( Halsey, MJ; Meldrum, BS; Wardley-Smith, B, 1984)
"Relative to wild-type (WT) mice, the tremor mice presented: increased tremors and bradykinesia associated with postural instability, decreased range of motion, and difficulty in initiating voluntary movements directly proportional to age; reduced step length for right and left hindlimbs; reduced cortical GABA, glutamate and, aspartate levels, the DOPAC/DA and ratio and increased the NOR levels; in the striatum, the levels of glycine and aspartate were reduced while the HVA levels, the HVA/DA and 5HIAA/5-HT ratios increased; in the cerebellum the glycine, NOR and 5-HIAA levels increased."4.31Progressive tremor and motor impairment in seizure-prone mutant tremor mice are associated with neurotransmitter dysfunction. ( Alexandre-Ribeiro, SR; Bernardi, MM; Bondan, EF; Coque, AC; Flório, JC; Garcia-Gomes, MSA; Gonçalves, FB; Kirsten, TB; Lebrun, I; Massironi, SMG; Mori, CMC; Sandini, TM; Silva-Sampaio, AC, 2023)
" tremor, myoclonus and convulsions, successively appear, have been studied in fed and fasted rats with and without pretreatment with 2-amino-7-phosphonoheptanoic acid (180 mg/kg)."3.67The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats. ( Halsey, MJ; Meldrum, BS; Wardley-Smith, B, 1984)
"Concentrations of putative neuroactive substances glutamate, aspartate, gamma-aminobutyric acid, glycine, proline and ethanolamine were determined in ventricular cerebrospinal fluid collected in patients suffering from Parkinson's disease, pain syndromes or cerebellar tremor."3.67Ventricular cerebrospinal fluid concentrations of putative amino acid transmitters in Parkinson's disease and other disorders. ( Amsler, U; Cuénod, M; Perschak, H; Siegfried, J; Vischer, A, 1987)
"The neurochemical effects of the tremorgenic mycotoxins Verruculogen and Penitrem A, which produce a neurotoxic syndrome characterised by sustained tremors, were studied using sheep and rat synaptosomes."3.66Actions of tremorgenic fungal toxins on neurotransmitter release. ( Bradford, HF; De Belleroche, J; Mantle, PG; Norris, PJ; Penny, RH; Smith, CC; Thomas, AJ, 1980)
"The pathogenesis of orthostatic tremor (OT) remains unclear, although some evidence points to dysfunction in the brainstem or cerebellum."1.43In vivo neurometabolic profiling in orthostatic tremor. ( Álvarez-Linera, J; Benito-León, J; Dydak, U; Hernández-Tamames, JA; Louis, ED; Malpica, N; Matarazzo, M; Mato-Abad, V; Molina-Arjona, JA; Romero, JP; Sánchez-Ferro, Á, 2016)
"A slowly progressive sensory ataxia and tremor manifested at the age of 3 to 16 years and distal spasticity in adolescence."1.32Five new cases of a recently described leukoencephalopathy with high brain lactate. ( Aärimaa, T; Autti, T; Häkkinen, AM; Koillinen, H; Kuusi, T; Linnankivi, T; Lönnqvist, T; Lundbom, N; Pihko, H; Sainio, K; Valanne, L, 2004)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's2 (15.38)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Gonçalves, FB1
Garcia-Gomes, MSA1
Silva-Sampaio, AC1
Kirsten, TB1
Bondan, EF1
Sandini, TM1
Flório, JC1
Lebrun, I1
Coque, AC1
Alexandre-Ribeiro, SR1
Massironi, SMG1
Mori, CMC1
Bernardi, MM1
Barbagallo, G1
Arabia, G1
Morelli, M1
Nisticò, R1
Novellino, F1
Salsone, M1
Rocca, F1
Quattrone, A2
Caracciolo, M1
Sabatini, U1
Cherubini, A1
Benito-León, J1
Louis, ED1
Mato-Abad, V1
Dydak, U1
Álvarez-Linera, J1
Hernández-Tamames, JA1
Molina-Arjona, JA1
Malpica, N1
Matarazzo, M1
Romero, JP1
Sánchez-Ferro, Á1
Baik, HM1
Choe, BY1
Son, BC1
Jeun, SS1
Kim, MC1
Lee, KS1
Kim, BS1
Lee, JM1
Lee, HK1
Suh, TS1
Linnankivi, T1
Lundbom, N1
Autti, T1
Häkkinen, AM1
Koillinen, H1
Kuusi, T1
Lönnqvist, T1
Sainio, K1
Valanne, L1
Aärimaa, T1
Pihko, H1
McPhee, SW1
Francis, J1
Janson, CG1
Serikawa, T3
Hyland, K1
Ong, EO1
Raghavan, SS1
Freese, A1
Leone, P1
Hanaya, R1
Kiura, Y1
Kurisu, K1
Sakai, N1
Sasa, M2
Norris, PJ1
Smith, CC1
De Belleroche, J1
Bradford, HF1
Mantle, PG1
Thomas, AJ1
Penny, RH1
Wardley-Smith, B1
Meldrum, BS1
Halsey, MJ1
Kitada, K1
Akimitsu, T1
Shigematsu, Y1
Kondo, A1
Maihara, T1
Yokoi, N1
Kuramoto, T1
Feigenbaum, JJ1
Bergmann, F1
Richmond, SA1
Mechoulam, R1
Nadler, V1
Kloog, Y1
Sokolovsky, M1
Perschak, H1
Amsler, U1
Vischer, A1
Siegfried, J1
Cuénod, M1
Baker, WW1

Other Studies

13 other studies available for aspartic acid and Tremor

ArticleYear
Progressive tremor and motor impairment in seizure-prone mutant tremor mice are associated with neurotransmitter dysfunction.
    Behavioural brain research, 2023, 04-12, Volume: 443

    Topics: Animals; Aspartic Acid; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine;

2023
Thalamic neurometabolic alterations in tremulous Parkinson's disease: A preliminary proton MR spectroscopy study.
    Parkinsonism & related disorders, 2017, Volume: 43

    Topics: Aged; Aspartic Acid; Choline; Creatine; Discriminant Analysis; Dopamine Plasma Membrane Transport Pr

2017
In vivo neurometabolic profiling in orthostatic tremor.
    Medicine, 2016, Volume: 95, Issue:37

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Case-Control Studies; Cerebellum; Cerebral Cortex; Di

2016
Proton MR spectroscopic changes in Parkinson's diseases after thalamotomy.
    European journal of radiology, 2003, Volume: 47, Issue:3

    Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Mal

2003
Five new cases of a recently described leukoencephalopathy with high brain lactate.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Adolescent; Aspartic Acid; Ataxia; Brain Chemistry; Brain Diseases, Metabolic; Brain Stem; Central N

2004
Effects of AAV-2-mediated aspartoacylase gene transfer in the tremor rat model of Canavan disease.
    Brain research. Molecular brain research, 2005, Apr-27, Volume: 135, Issue:1-2

    Topics: Amidohydrolases; Analysis of Variance; Animals; Aspartic Acid; Behavior, Animal; Brain; Canavan Dise

2005
N-acetyl-L-aspartate activates hippocampal CA3 neurons in rodent slice preparations.
    Brain research bulletin, 2008, Mar-28, Volume: 75, Issue:5

    Topics: Animals; Aspartic Acid; Cadmium; Dioxolanes; Disease Models, Animal; Drug Interactions; Electric Sti

2008
Actions of tremorgenic fungal toxins on neurotransmitter release.
    Journal of neurochemistry, 1980, Volume: 34, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Acid; Glut

1980
The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats.
    Neuroscience letters, 1984, Jul-27, Volume: 48, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Brain; Fasti

1984
Accumulation of N-acetyl-L-aspartate in the brain of the tremor rat, a mutant exhibiting absence-like seizure and spongiform degeneration in the central nervous system.
    Journal of neurochemistry, 2000, Volume: 74, Issue:6

    Topics: Amidohydrolases; Animals; Aspartic Acid; Base Sequence; Blotting, Southern; Central Nervous System;

2000
Nonpsychotropic cannabinoid acts as a functional N-methyl-D-aspartate receptor blocker.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:23

    Topics: Animals; Aspartic Acid; Cell Membrane; Cerebral Cortex; Dronabinol; Heart Rate; Mice; Mice, Inbred C

1989
Ventricular cerebrospinal fluid concentrations of putative amino acid transmitters in Parkinson's disease and other disorders.
    Human neurobiology, 1987, Volume: 6, Issue:3

    Topics: Adult; Aged; Amino Acids; Aspartic Acid; Ethanolamine; Ethanolamines; Female; gamma-Aminobutyric Aci

1987
Excitatory responses following intracaudate injection of N-methyl-dl-aspartic acid.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 196, Issue:2

    Topics: Aggression; Animals; Arousal; Aspartic Acid; Carbachol; Cats; Caudate Nucleus; Humans; Male; Methyla

1972