aspartic acid has been researched along with Thiamine Deficiency in 13 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Thiamine Deficiency: A nutritional condition produced by a deficiency of THIAMINE in the diet, characterized by anorexia, irritability, and weight loss. Later, patients experience weakness, peripheral neuropathy, headache, and tachycardia. In addition to being caused by a poor diet, thiamine deficiency in the United States most commonly occurs as a result of alcoholism, since ethanol interferes with thiamine absorption. In countries relying on polished rice as a dietary staple, BERIBERI prevalence is very high. (From Cecil Textbook of Medicine, 19th ed, p1171)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thiamine-deficient encephalopathy in the rat is characterized by ataxic gait, loss of righting reflex and curvature of the spine." | 1.26 | Amino acid changes in thiamine-deficient encephalopathy: some implications for the pathogenesis of Friedreich's ataxia. ( Barbeau, A; Butterworth, RF; Hamel, E; Landreville, F, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (92.31) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawakami, Z | 1 |
| Kanno, H | 1 |
| Ueki, T | 1 |
| Terawaki, K | 1 |
| Tabuchi, M | 1 |
| Ikarashi, Y | 1 |
| Kase, Y | 1 |
| GANTI, Y | 1 |
| SHANMUGASUNDARAM, ER | 1 |
| Benevenga, NJ | 1 |
| Baldwin, RL | 1 |
| Ronning, M | 1 |
| Black, AL | 1 |
| Plaitakis, A | 2 |
| Hwang, EC | 1 |
| Woert, MH | 1 |
| Szilagyi, PE | 1 |
| Berl, S | 2 |
| Hamel, E | 2 |
| Butterworth, RF | 3 |
| Barbeau, A | 2 |
| Gaitonde, MK | 2 |
| Nicklas, WJ | 1 |
| Landreville, F | 1 |
| Meghal, SK | 1 |
| O'Neal, RM | 2 |
| Koeppe, RE | 2 |
| Héroux, M | 1 |
| Neujahr, HY | 1 |
| Nixey, RW | 1 |
| Sharman, IM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Traditional Chinese Medicine (VGH-AD1) on Patients With Alzheimer's Disease: A Double-blinded Randomized Placebo-controlled Cross-over Study[NCT04249869] | Phase 1/Phase 2 | 28 participants (Anticipated) | Interventional | 2020-02-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 other studies available for aspartic acid and Thiamine Deficiency
| Article | Year |
|---|---|
Neuroprotective effects of yokukansan, a traditional Japanese medicine, on glutamate-mediated excitotoxicity in cultured cells.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Cell Death; Cells, Cultured; C | 2009 |
VARIATION OF FREE AMINO ACIDS IN CORCYRA CEPHALONICA ST. (RICE MOTH LARVAE) DURING SOME B VITAMIN DEFICIENCIES.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chromatography; Glutamates; Glycine; Insecta; Larva; L | 1963 |
Pyruvate metabolism in thiamine-deficient calves.
Topics: Alanine; Animals; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Cattle; Coenzyme A; Glutamates; Gl | 1967 |
Effect of thiamin deficiency on brain neurotransmitter systems.
Topics: Acetylcholine; Animals; Aspartic Acid; Brain; Diet; Glutamates; Glutamic Acid; Guanosine Monophospha | 1982 |
Effect of thiamine deficiency on levels of putative amino acid transmitters in affected regions of the rat brain.
Topics: Animals; Aspartic Acid; Brain Chemistry; Cerebellum; gamma-Aminobutyric Acid; Glutamine; Glycine; Ma | 1979 |
Decreased turnover of N-acetylaspartate in the brain of thiamine-deficient rats.
Topics: Animals; Aspartic Acid; Brain; Male; Rats; Thiamine Deficiency | 1979 |
Alterations in uptake and metabolism of aspartate and glutamate in brain of thiamine deficient animals.
Topics: Animals; Aspartic Acid; Brain; Cerebellum; Glutamates; Glycine; Male; Medulla Oblongata; Pons; Rats; | 1979 |
Amino acid changes in thiamine-deficient encephalopathy: some implications for the pathogenesis of Friedreich's ataxia.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Diseases; Friedreich Ataxia; gamma-Aminobutyric Ac | 1979 |
Effect of thiamine deficiency, pyrithiamine and oxythiamine on pyruvate metabolism in rat liver and brain in vivo.
Topics: Animals; Aspartic Acid; Body Weight; Brain; Decarboxylation; Glutamates; Liver; Male; Oxythiamine; P | 1977 |
Effect of pyrithiamine treatment and subsequent thiamine rehabilitation on regional cerebral amino acids and thiamine-dependent enzymes.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Diseases; Glutamates; Glutamic Acid; Keto | 1989 |
Transport of B-vitamins in microorganisms. IV. The specificity of the high accumulation of labelled thiamine in non-proliferating thiamine deficient cells of L. fermenti.
Topics: Adenine; Aspartic Acid; Biotin; Carbon Isotopes; Cell Membrane Permeability; Glutamates; Lactobacill | 1966 |
The effect of deficiency of thiamine on the metabolism of (U-14C)glucose and (U-14C)ribose and the levels of amino acids in rat brain.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Body Weight; Brain; Carbon Radioisotop | 1974 |
Precursors in vivo of glutamate, aspartate and their derivatives of rat brain.
Topics: Acyltransferases; Aspartic Acid; Brain; Carbon Isotopes; Glucose; Glutamates; Glutamine; Glutathione | 1966 |