aspartic acid has been researched along with Stroke in 59 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We measured 4 plasma amino acid neurotransmitters (glutamic acid, aspartic acid, gamma-aminobutyric acid, and glycine) among 3486 patients with ischemic stroke from 26 hospitals across China." | 5.69 | Plasma Amino Acid Neurotransmitters and Ischemic Stroke Prognosis: A Multicenter Prospective Study. ( Chen, J; Guo, D; He, J; Jia, Y; Peng, H; Shi, M; Sun, L; Wang, A; Wang, Y; Xu, Q; Xu, T; Yang, P; Zhang, Y; Zhong, C; Zhu, Z, 2023) |
| "Lactate/choline ratio measured in the acute infarct core by 1H MRS improves the prediction of stroke outcome and provides prognostic information complementary to DWI." | 5.09 | Combined (1)H MR spectroscopy and diffusion-weighted MRI improves the prediction of stroke outcome. ( Barber, PA; Darby, DG; Davis, SM; Desmond, PM; Gerraty, RP; Li, T; Parsons, MW; Tress, BM; Yang, Q, 2000) |
| "Lesional NAA and creatine were significantly lower in subacute than in acute stroke." | 4.31 | Predicting the Onset of Ischemic Stroke With Fast High-Resolution 3D MR Spectroscopic Imaging. ( Bo, B; Guan, Y; Guo, R; Li, Y; Liang, ZP; Lin, DJ; Lin, Z; Liu, J; Meng, Z; Nachev, P; Wang, T; Yu, X; Zhao, Y; Zhou, H, 2023) |
| "To assess the utility of Magnetic Resonance Spectroscopy (MRS) as a biomarker of response to L-arginine in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS)." | 3.91 | MELAS: Monitoring treatment with magnetic resonance spectroscopy. ( Chong, RA; DeGiorgio, CM; Galati, A; Hovsepian, DA; Mazumder, R; Mishra, S; Yim, C, 2019) |
| "The NAA/Cr (N-acetyl aspartate/creatine) of the bilateral hippocampus of the cognitive impairment group was lower than those of both control group of stroke and health (p < 0." | 3.85 | Study on the clinical application of the MRS in the cognitive assessment after stroke. ( Chen, W; Gong, ZK; Sheng, C; Wang, M; Wang, SY; Wang, XX, 2017) |
| "Emerging evidence has suggested that hydrogen sulfide (H2S) may alleviate the cellular damage associated with cerebral ischemia/reperfusion (I/R) injury." | 3.85 | The administration of hydrogen sulphide prior to ischemic reperfusion has neuroprotective effects in an acute stroke model. ( Choi, CG; Choi, Y; Ha, HK; Ham, SJ; Jeon, SB; Jung, SC; Kim, J; Kim, JK; Kim, KW; Kim, ST; Kwon, JI; Shim, WH; Sung, YS; Woo, CW; Woo, DC, 2017) |
| "To clarify the roles of serial MR spectroscopy (MRS) and continuous arterial spin labeling (CASL) perfusion images for evaluating cerebral lesions in patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS)." | 3.76 | Pathophysiologic evaluation of MELAS strokes by serially quantified MRS and CASL perfusion images. ( Ikawa, M; Kimura, H; Kudo, T; Kuriyama, M; Okazawa, H; Shimizu, Y; Toyooka, M; Tsujikawa, T; Uematsu, H; Yoneda, M, 2010) |
| " We show that modulation of the eNOS serine 1179 (S1179) phosphorylation site affects vascular reactivity and determines stroke size in vivo." | 3.74 | The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo. ( Atochin, DN; Ayata, C; Critchlow, JD; Dantas, AP; Huang, PL; Liu, VW; Looft-Wilson, R; Michel, T; Moskowitz, MA; Murata, T; Salomone, S; Sessa, WC; Shin, HK; Wang, A, 2007) |
| "NAA/choline (Cho) ratios were significantly reduced in both areas of T2 hyperintensity and in surrounding tissue." | 2.70 | Spectroscopic data following stroke reveal tissue abnormality beyond the region of T2-weighted hyperintensity. ( Beley, A; Brunotte, F; Demougeot, C; Giroud, M; Marie, C; Rouaud, O; Walker, P, 2002) |
| "Diffuse leukoencephalopathy associated with ocular malformations of the Axenfeld-Rieger type was observed in five individuals." | 1.34 | COL4A1 mutation in Axenfeld-Rieger anomaly with leukoencephalopathy and stroke. ( Arveiler, B; Bouchet, JP; Burgelin, I; Calvas, P; Coupry, I; Dousset, V; Goizet, C; Gorry, P; Lacombe, D; Menegon, P; Orgogozo, JM; Orignac, I; Sibon, I, 2007) |
| "We introduced intracerebral hemorrhage in each of eight anesthetized New Zealand rabbits by injecting 0." | 1.32 | Extracellular glutamate and other amino acids in experimental intracerebral hemorrhage: an in vivo microdialysis study. ( Ali, Z; Baker, G; Guterman, LR; Hopkins, LN; Qureshi, AI; Shuaib, A; Suri, MF; Todd, K, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.69) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 33 (55.93) | 29.6817 |
| 2010's | 21 (35.59) | 24.3611 |
| 2020's | 4 (6.78) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, MN | 1 |
| Hao, XY | 1 |
| Tian, J | 1 |
| Wang, YC | 1 |
| Li, JD | 1 |
| Fan, Y | 1 |
| Shi, JJ | 1 |
| Ma, DR | 1 |
| Li, SJ | 1 |
| Zuo, CY | 1 |
| Liang, YY | 1 |
| Li, MJ | 1 |
| Shen, S | 1 |
| Liu, F | 1 |
| Yao, DB | 1 |
| Xu, YM | 1 |
| Shi, CH | 1 |
| Lin, Z | 1 |
| Meng, Z | 1 |
| Wang, T | 1 |
| Guo, R | 1 |
| Zhao, Y | 1 |
| Li, Y | 3 |
| Bo, B | 1 |
| Guan, Y | 1 |
| Liu, J | 2 |
| Zhou, H | 1 |
| Yu, X | 1 |
| Lin, DJ | 1 |
| Liang, ZP | 1 |
| Nachev, P | 1 |
| Zhu, Z | 1 |
| Yang, P | 1 |
| Jia, Y | 1 |
| Wang, Y | 1 |
| Shi, M | 1 |
| Zhong, C | 1 |
| Peng, H | 1 |
| Sun, L | 1 |
| Guo, D | 1 |
| Xu, Q | 1 |
| Chen, J | 1 |
| Wang, A | 2 |
| Xu, T | 1 |
| He, J | 2 |
| Zhang, Y | 2 |
| Ferris, JK | 1 |
| Neva, JL | 1 |
| Vavasour, IM | 1 |
| Attard, KJ | 1 |
| Greeley, B | 1 |
| Hayward, KS | 1 |
| Wadden, KP | 1 |
| MacKay, AL | 1 |
| Boyd, LA | 2 |
| Wang, SY | 1 |
| Wang, M | 1 |
| Wang, XX | 1 |
| Chen, W | 2 |
| Sheng, C | 1 |
| Gong, ZK | 1 |
| Woo, CW | 1 |
| Kwon, JI | 1 |
| Kim, KW | 1 |
| Kim, JK | 1 |
| Jeon, SB | 1 |
| Jung, SC | 1 |
| Choi, CG | 1 |
| Kim, ST | 1 |
| Kim, J | 1 |
| Ham, SJ | 1 |
| Shim, WH | 1 |
| Sung, YS | 1 |
| Ha, HK | 1 |
| Choi, Y | 1 |
| Woo, DC | 1 |
| Hovsepian, DA | 1 |
| Galati, A | 1 |
| Chong, RA | 1 |
| Mazumder, R | 1 |
| DeGiorgio, CM | 1 |
| Mishra, S | 1 |
| Yim, C | 1 |
| Takatsuru, Y | 1 |
| Eto, K | 1 |
| Kaneko, R | 1 |
| Masuda, H | 1 |
| Shimokawa, N | 1 |
| Koibuchi, N | 1 |
| Nabekura, J | 1 |
| Shemesh, N | 1 |
| Rosenberg, JT | 1 |
| Dumez, JN | 1 |
| Grant, SC | 1 |
| Frydman, L | 1 |
| Chouchani, ET | 1 |
| Pell, VR | 1 |
| Gaude, E | 1 |
| Aksentijević, D | 1 |
| Sundier, SY | 1 |
| Robb, EL | 1 |
| Logan, A | 1 |
| Nadtochiy, SM | 1 |
| Ord, ENJ | 1 |
| Smith, AC | 1 |
| Eyassu, F | 1 |
| Shirley, R | 1 |
| Hu, CH | 1 |
| Dare, AJ | 1 |
| James, AM | 1 |
| Rogatti, S | 1 |
| Hartley, RC | 1 |
| Eaton, S | 1 |
| Costa, ASH | 1 |
| Brookes, PS | 1 |
| Davidson, SM | 1 |
| Duchen, MR | 1 |
| Saeb-Parsy, K | 1 |
| Shattock, MJ | 1 |
| Robinson, AJ | 1 |
| Work, LM | 1 |
| Frezza, C | 1 |
| Krieg, T | 1 |
| Murphy, MP | 1 |
| Igarashi, H | 1 |
| Suzuki, Y | 1 |
| Huber, VJ | 1 |
| Ida, M | 1 |
| Nakada, T | 1 |
| Moore, SA | 1 |
| Hallsworth, K | 1 |
| Jakovljevic, DG | 1 |
| Blamire, AM | 3 |
| Ford, GA | 1 |
| Rochester, L | 1 |
| Trenell, MI | 1 |
| Esparza-García, JC | 1 |
| Santiago-Germán, D | 1 |
| Guadalupe Valades-Mejía, M | 1 |
| Hernández-Juárez, J | 1 |
| Aguilar-Sosa, E | 1 |
| Leaños-Miranda, A | 1 |
| Alvarado-Moreno, A | 1 |
| Majluf-Cruz, A | 1 |
| Isordia-Salas, I | 1 |
| Xiang, J | 1 |
| Tang, Y | 1 |
| Li, C | 1 |
| Su, EJ | 1 |
| Lawrence, DA | 1 |
| Keep, RF | 1 |
| Tauskela, JS | 1 |
| Aylsworth, A | 1 |
| Hewitt, M | 1 |
| Brunette, E | 1 |
| Blondeau, N | 1 |
| Meng, N | 1 |
| Shi, S | 1 |
| Su, Y | 1 |
| Jones, PW | 1 |
| Borich, MR | 1 |
| Vavsour, I | 1 |
| Mackay, A | 1 |
| Carlson, HL | 1 |
| MacMaster, FP | 1 |
| Harris, AD | 1 |
| Kirton, A | 1 |
| van der Zijden, JP | 1 |
| van Eijsden, P | 1 |
| de Graaf, RA | 1 |
| Dijkhuizen, RM | 1 |
| Baron, JC | 1 |
| van Baalen, A | 1 |
| Stephani, U | 1 |
| Rohr, A | 1 |
| Muñoz Maniega, S | 1 |
| Cvoro, V | 2 |
| Chappell, FM | 1 |
| Armitage, PA | 2 |
| Marshall, I | 3 |
| Bastin, ME | 2 |
| Wardlaw, JM | 3 |
| Rivers, CS | 1 |
| Carpenter, TK | 1 |
| Wartolowska, K | 1 |
| Farrall, AJ | 1 |
| Dennis, MS | 1 |
| Tsujikawa, T | 1 |
| Yoneda, M | 1 |
| Shimizu, Y | 1 |
| Uematsu, H | 1 |
| Toyooka, M | 1 |
| Ikawa, M | 1 |
| Kudo, T | 1 |
| Okazawa, H | 1 |
| Kuriyama, M | 1 |
| Kimura, H | 1 |
| An, L | 1 |
| Thomasson, DM | 1 |
| Latour, LL | 1 |
| Baker, EH | 1 |
| Shen, J | 1 |
| Warach, S | 1 |
| Huang, Y | 1 |
| Wu, X | 1 |
| Shi, X | 1 |
| Geng, D | 1 |
| Domingues-Montanari, S | 1 |
| Fernandez-Cadenas, I | 1 |
| del Rio-Espinola, A | 1 |
| Mendioroz, M | 1 |
| Ribo, M | 1 |
| Obach, V | 1 |
| Marti-Fabregas, J | 1 |
| Freijo, M | 1 |
| Serena, J | 1 |
| Corbeto, N | 1 |
| Chacon, P | 1 |
| Alvarez-Sabin, J | 1 |
| Montaner, J | 1 |
| Wang, X | 1 |
| Li, YH | 1 |
| Li, MH | 1 |
| Lu, J | 1 |
| Zhao, JG | 1 |
| Sun, XJ | 1 |
| Zhang, B | 1 |
| Ye, JL | 1 |
| Reismann, P | 1 |
| Xiong, L | 1 |
| Hu, M | 1 |
| Zhang, X | 1 |
| Jing, Z | 1 |
| Li, T | 2 |
| Li, G | 1 |
| Yu, Y | 1 |
| Meng, F | 1 |
| Wang, Z | 1 |
| Craciunas, SC | 1 |
| Brooks, WM | 1 |
| Nudo, RJ | 1 |
| Popescu, EA | 1 |
| Choi, IY | 1 |
| Lee, P | 1 |
| Yeh, HW | 1 |
| Savage, CR | 1 |
| Cirstea, CM | 1 |
| Demougeot, C | 2 |
| Bertrand, N | 1 |
| Prigent-Tessier, A | 1 |
| Garnier, P | 1 |
| Mossiat, C | 1 |
| Giroud, M | 3 |
| Marie, C | 2 |
| Beley, A | 2 |
| Qureshi, AI | 1 |
| Ali, Z | 1 |
| Suri, MF | 1 |
| Shuaib, A | 1 |
| Baker, G | 1 |
| Todd, K | 1 |
| Guterman, LR | 1 |
| Hopkins, LN | 1 |
| Nicoli, F | 1 |
| Lefur, Y | 1 |
| Denis, B | 1 |
| Ranjeva, JP | 1 |
| Confort-Gouny, S | 1 |
| Cozzone, PJ | 1 |
| SAITO, T | 1 |
| Vial, F | 1 |
| Serriere, S | 1 |
| Barantin, L | 1 |
| Montharu, J | 1 |
| Nadal-Desbarats, L | 1 |
| Pourcelot, L | 1 |
| Seguin, F | 1 |
| Walker, PM | 1 |
| Ben Salem, D | 1 |
| Lalande, A | 1 |
| Brunotte, F | 2 |
| Stengel, A | 1 |
| Neumann-Haefelin, T | 1 |
| Singer, OC | 1 |
| Neumann-Haefelin, C | 1 |
| Zanella, FE | 1 |
| Lanfermann, H | 1 |
| Pilatus, U | 1 |
| Zee, RY | 1 |
| Hegener, HH | 1 |
| Gould, J | 1 |
| Ridker, PM | 1 |
| Ross, AJ | 2 |
| Sachdev, PS | 2 |
| Wen, W | 2 |
| Valenzuela, MJ | 1 |
| Brodaty, H | 2 |
| Kim, HC | 1 |
| Kang, DR | 1 |
| Nam, CM | 1 |
| Hur, NW | 1 |
| Shim, JS | 1 |
| Jee, SH | 1 |
| Suh, I | 1 |
| Glodzik-Sobanska, L | 2 |
| Slowik, A | 2 |
| Kieltyka, A | 1 |
| Kozub, J | 1 |
| Sobiecka, B | 2 |
| Urbanik, A | 1 |
| Szczudlik, A | 2 |
| Joscelyne, A | 1 |
| Lorentz, LM | 1 |
| Berger, K | 1 |
| Stögbauer, F | 1 |
| Stoll, M | 1 |
| Wellmann, J | 1 |
| Huge, A | 1 |
| Cheng, S | 1 |
| Kessler, C | 1 |
| John, U | 1 |
| Assmann, G | 1 |
| Ringelstein, EB | 1 |
| Funke, H | 1 |
| Li, J | 1 |
| Mosconi, L | 1 |
| Walecki, J | 1 |
| de Leon, MJ | 1 |
| Lipski, J | 1 |
| Wan, CK | 1 |
| Bai, JZ | 1 |
| Pi, R | 1 |
| Li, D | 1 |
| Donnelly, D | 1 |
| Atochin, DN | 1 |
| Liu, VW | 1 |
| Critchlow, JD | 1 |
| Dantas, AP | 1 |
| Looft-Wilson, R | 1 |
| Murata, T | 1 |
| Salomone, S | 1 |
| Shin, HK | 1 |
| Ayata, C | 1 |
| Moskowitz, MA | 1 |
| Michel, T | 1 |
| Sessa, WC | 1 |
| Huang, PL | 1 |
| Sibon, I | 1 |
| Coupry, I | 1 |
| Menegon, P | 1 |
| Bouchet, JP | 1 |
| Gorry, P | 1 |
| Burgelin, I | 1 |
| Calvas, P | 1 |
| Orignac, I | 1 |
| Dousset, V | 1 |
| Lacombe, D | 1 |
| Orgogozo, JM | 1 |
| Arveiler, B | 1 |
| Goizet, C | 1 |
| Singhal, AB | 1 |
| Ratai, E | 1 |
| Benner, T | 1 |
| Vangel, M | 1 |
| Lee, V | 1 |
| Koroshetz, WJ | 1 |
| Schaefer, PW | 1 |
| Sorensen, AG | 1 |
| Gonzalez, RG | 1 |
| Pineiro, R | 1 |
| Pendlebury, ST | 2 |
| Smith, S | 1 |
| Flitney, D | 1 |
| Styles, P | 2 |
| Matthews, PM | 2 |
| Lee, MA | 1 |
| Akar, N | 1 |
| Akar, E | 1 |
| Deda, G | 1 |
| Sipahi, T | 1 |
| Parsons, MW | 1 |
| Barber, PA | 1 |
| Yang, Q | 1 |
| Darby, DG | 1 |
| Desmond, PM | 1 |
| Gerraty, RP | 1 |
| Tress, BM | 1 |
| Davis, SM | 1 |
| Wild, JM | 1 |
| Warlow, CP | 1 |
| Dawson, DA | 1 |
| Wadsworth, G | 1 |
| Palmer, AM | 1 |
| Pearl, PL | 1 |
| Krasnewich, D | 1 |
| Kobayashi, M | 1 |
| Takayama, H | 1 |
| Suga, S | 1 |
| Mihara, B | 1 |
| Chu, WJ | 1 |
| Mason, GF | 1 |
| Pan, JW | 1 |
| Hetherington, HP | 1 |
| Liu, HG | 1 |
| San Pedro, EC | 1 |
| Mountz, JM | 1 |
| Walker, P | 1 |
| Rouaud, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Trial of Normobaric Oxygen Therapy in Acute Ischemic Stroke[NCT00414726] | Phase 2 | 85 participants (Actual) | Interventional | 2007-01-31 | Terminated (stopped due to Imbalance in deaths favoring control arm; deaths not attributed to treatment by the blinded external medical monitor.) | ||
| Remote Effects of Stroke on Cerebral Metabolism. Evaluation With Positron Emission Tomography and Proton Magnetic Resonance Spectroscopy[NCT00063180] | 70 participants | Observational | 2003-06-19 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The NIHSS score ranges from 0 (best score) to 42 (worst score). (NCT00414726)
Timeframe: 4 hours after starting treatment
| Intervention | 0-4 hour change in NIHSS score (Mean) |
|---|---|
| Normobaric Oxygen | -0.37 |
| Room Air | -0.43 |
The NIHSS score ranges from 0 (best score) to 42 (worst score). (NCT00414726)
Timeframe: 24 hours
| Intervention | 0-24 hour change in NIHSS score (Mean) |
|---|---|
| Normobaric Oxygen | 0.17 |
| Room Air | -0.73 |
2 reviews available for aspartic acid and Stroke
| Article | Year |
|---|---|
N-acetylaspartate decrease in acute stage of ischemic stroke: a perspective from experimental and clinical studies.
Topics: Acute Disease; Animals; Aspartic Acid; Brain; Brain Ischemia; Humans; Magnetic Resonance Spectroscop | 2015 |
Mechanisms Underlying Astrocyte Endfeet Swelling in Stroke.
Topics: Animals; Aspartic Acid; Astrocytes; Blood-Brain Barrier; Brain Ischemia; Cell Size; Edema; Glutamic | 2016 |
9 trials available for aspartic acid and Stroke
| Article | Year |
|---|---|
Plasma Amino Acid Neurotransmitters and Ischemic Stroke Prognosis: A Multicenter Prospective Study.
Topics: Aspartic Acid; Biomarkers; Brain Ischemia; Cohort Studies; gamma-Aminobutyric Acid; Glutamic Acid; G | 2023 |
Effects of Community Exercise Therapy on Metabolic, Brain, Physical, and Cognitive Function Following Stroke: A Randomized Controlled Pilot Trial.
Topics: Aged; Aspartic Acid; Body Composition; Brain; Cognition Disorders; Exercise Test; Exercise Therapy; | 2015 |
Metabolic counterpart of decreased apparent diffusion coefficient during hyperacute ischemic stroke: a brain proton magnetic resonance spectroscopic imaging study.
Topics: Acute Disease; Adult; Aged; Aspartic Acid; Brain; Brain Ischemia; Cerebrovascular Circulation; Diffu | 2003 |
1H MRS in stroke patients with and without cognitive impairment.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Cerebral Cortex; Choline; Cognition Disorders; C | 2005 |
Magnetic resonance spectroscopy study of oxygen therapy in ischemic stroke.
Topics: Acute Disease; Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Ischemia; Diffusion Magnetic Res | 2007 |
Combined (1)H MR spectroscopy and diffusion-weighted MRI improves the prediction of stroke outcome.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Diffusion; Female; Humans; Infarction, Middl | 2000 |
Longitudinal changes of metabolites in frontal lobes after hemorrhagic stroke of basal ganglia: a proton magnetic resonance spectroscopy study.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Basal Ganglia Hemorrhage; Creatine; Disease Progression; Fem | 2001 |
Regional cerebral blood flow and magnetic resonance spectroscopic imaging findings in diaschisis from stroke.
Topics: Adult; Aged; Aspartic Acid; Blood Flow Velocity; Brain; Cerebral Infarction; Cerebrovascular Circula | 2002 |
Spectroscopic data following stroke reveal tissue abnormality beyond the region of T2-weighted hyperintensity.
Topics: Aspartic Acid; Choline; Creatine; Female; Humans; Infarction, Middle Cerebral Artery; Lactic Acid; M | 2002 |
48 other studies available for aspartic acid and Stroke
| Article | Year |
|---|---|
Human blood metabolites and lacunar stroke: A Mendelian randomization study.
Topics: Aspartic Acid; Genome-Wide Association Study; Humans; Lipids; Mendelian Randomization Analysis; Poly | 2023 |
Predicting the Onset of Ischemic Stroke With Fast High-Resolution 3D MR Spectroscopic Imaging.
Topics: Aspartic Acid; Bayes Theorem; Choline; Creatine; Cross-Sectional Studies; Humans; Ischemic Stroke; L | 2023 |
Cortical N-acetylaspartate concentrations are impacted in chronic stroke but do not relate to motor impairment: A magnetic resonance spectroscopy study.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Chronic Disease; Female; Humans; Magnetic Resonance S | 2021 |
Study on the clinical application of the MRS in the cognitive assessment after stroke.
Topics: Aspartic Acid; Cognition; Cognition Disorders; Cognitive Dysfunction; Creatine; Hippocampus; Humans; | 2017 |
The administration of hydrogen sulphide prior to ischemic reperfusion has neuroprotective effects in an acute stroke model.
Topics: Animals; Apoptosis; Aspartic Acid; Brain Ischemia; Disease Models, Animal; Glutamic Acid; Humans; Hy | 2017 |
MELAS: Monitoring treatment with magnetic resonance spectroscopy.
Topics: Arginine; Aspartic Acid; Brain; Choline; Female; Humans; Magnetic Resonance Spectroscopy; MELAS Synd | 2019 |
Critical role of the astrocyte for functional remodeling in contralateral hemisphere of somatosensory cortex after stroke.
Topics: Aminomethyltransferase; Analysis of Variance; Animals; Aspartic Acid; Astrocytes; Calcium; Disease M | 2013 |
Metabolic T1 dynamics and longitudinal relaxation enhancement in vivo at ultrahigh magnetic fields on ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebral Angiography; Cerebrovascular Circulation; Choline; | 2014 |
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Topics: Adenosine Monophosphate; Animals; Aspartic Acid; Citric Acid Cycle; Disease Models, Animal; Electron | 2014 |
GLU298ASP and 4G/5G Polymorphisms and the Risk of Ischemic Stroke in Young Individuals.
Topics: Adult; Aspartic Acid; Brain Ischemia; Case-Control Studies; DNA Mutational Analysis; Female; Gene Fr | 2015 |
Failure and rescue of preconditioning-induced neuroprotection in severe stroke-like insults.
Topics: 4-Aminopyridine; Animals; Aspartic Acid; Bicuculline; Cell Hypoxia; Cells, Cultured; Cerebral Cortex | 2016 |
Proton magnetic resonance spectroscopy as a diagnostic biomarker in mild cognitive impairment following stroke in acute phase.
Topics: Aged; Aspartic Acid; Biomarkers; Cognitive Dysfunction; Creatine; Female; Hippocampus; Humans; Male; | 2016 |
Cortical thickness and metabolite concentration in chronic stroke and the relationship with motor function.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Cerebral Cortex; Female; Glutamic Acid; Glutamine; Humans; M | 2016 |
Spectroscopic biomarkers of motor cortex developmental plasticity in hemiparetic children after perinatal stroke.
Topics: Adolescent; Analysis of Variance; Aspartic Acid; Cerebral Palsy; Child; Choline; Female; Glutamic Ac | 2017 |
1H/13C MR spectroscopic imaging of regionally specific metabolic alterations after experimental stroke.
Topics: Animals; Aspartic Acid; Brain; Carbon Isotopes; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Magn | 2008 |
Metabolism of DWI lesions: implications for rescue therapy.
Topics: Acute Disease; Animals; Aspartic Acid; Cell Hypoxia; Cerebrovascular Circulation; Diffusion Magnetic | 2007 |
Increased brain lactate during stroke-like episode in a patient with congenital disorder of glycosylation type Ia.
Topics: Acidosis, Lactic; Aspartic Acid; Brain; Carbohydrate Metabolism, Inborn Errors; Child; Female; Fever | 2009 |
Changes in NAA and lactate following ischemic stroke: a serial MR spectroscopic imaging study.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Brain; Brain Ischemia; Brain Mapping; Cel | 2008 |
Associations between diffusion and perfusion parameters, N-acetyl aspartate, and lactate in acute ischemic stroke.
Topics: Acute Disease; Aspartic Acid; Brain Ischemia; Cell Death; Cerebrovascular Circulation; Diffusion Mag | 2009 |
Pathophysiologic evaluation of MELAS strokes by serially quantified MRS and CASL perfusion images.
Topics: Adult; Aspartic Acid; Brain; Cerebrovascular Circulation; Child; Diagnostic Imaging; Female; Humans; | 2010 |
Measurement of glutathione in normal volunteers and stroke patients at 3T using J-difference spectroscopy with minimized subtraction errors.
Topics: Adult; Aspartic Acid; Biomarkers; Case-Control Studies; Choline; Creatine; Female; Glutathione; Huma | 2009 |
Effects of antidepressant treatment on N-acetyl aspartate and choline levels in the hippocampus and thalami of post-stroke depression patients: a study using (1)H magnetic resonance spectroscopy.
Topics: Aged; Analysis of Variance; Antidepressive Agents; Aspartic Acid; Brain Mapping; Case-Control Studie | 2010 |
The I/D polymorphism of the ACE1 gene is not associated with ischaemic stroke in Spanish individuals.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Female; Gene Frequency; Genome-Wide Association Study; Genot | 2010 |
Glutamate level detection by magnetic resonance spectroscopy in patients with post-stroke depression.
Topics: Aged; Aspartic Acid; Brain; Brain Mapping; Creatine; Depression; Female; Glutamic Acid; Humans; Inos | 2012 |
[Study of the Toll-like receptor 4 gene polymorphisms in diseases presenting with subclinical and chronic inflammation].
Topics: Alleles; Aspartic Acid; Brain Ischemia; Chronic Disease; Cytokines; Diabetes Complications; Diabetic | 2011 |
Association between Glu298Asp/677C-T single nucleotide polymorphism in the eNOS/MTHRF gene and blood stasis syndrome of ischemic stroke.
Topics: Aged; Aspartic Acid; Base Sequence; Brain Ischemia; DNA Primers; Female; Glutamic Acid; Hemostasis; | 2012 |
Motor and premotor cortices in subcortical stroke: proton magnetic resonance spectroscopy measures and arm motor impairment.
Topics: Adult; Aged; Aspartic Acid; Female; Functional Laterality; Humans; Imaging, Three-Dimensional; Magne | 2013 |
Reversible loss of N-acetyl-aspartate in rats subjected to long-term focal cerebral ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Chromatography, High Pressure Liquid; Chronic Disease; Male; | 2003 |
Extracellular glutamate and other amino acids in experimental intracerebral hemorrhage: an in vivo microdialysis study.
Topics: Analysis of Variance; Animals; Asparagine; Aspartic Acid; Brain Ischemia; Cerebral Hemorrhage; Chrom | 2003 |
[THE PROPHYLACTIC EFFECT OF HEAD-COOLING ON HEAT-STROKE. IV. THE EFFECT OF COMBINED TREATMENT OF HEAD-COOLING AND ADMINISTRATION OF ASPARTIC SALT ON ELECTROCARDIOGRAM].
Topics: Aspartic Acid; Coal Mining; Electrocardiography; Head; Heat Exhaustion; Heat Stroke; Hot Temperature | 1963 |
A newborn piglet study of moderate hypoxic-ischemic brain injury by 1H-MRS and MRI.
Topics: Animals; Animals, Newborn; Aspartic Acid; Basal Ganglia; Cerebral Cortex; Cerebrovascular Circulatio | 2004 |
Time course of NAA T2 and ADC(w) in ischaemic stroke patients: 1H MRS imaging and diffusion-weighted MRI.
Topics: Aged; Analysis of Variance; Aspartic Acid; Brain Ischemia; Brain Mapping; Diffusion Magnetic Resonan | 2004 |
Multiple spin-echo spectroscopic imaging for rapid quantitative assessment of N-acetylaspartate and lactate in acute stroke.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Analysis of Variance; Aspartic Acid; Case-Control Stu | 2004 |
Toll-like receptor 4 Asp299Gly gene polymorphism and risk of atherothrombosis.
Topics: Amino Acid Substitution; Aspartic Acid; Case-Control Studies; Genetic Predisposition to Disease; Gly | 2005 |
Elevated serum aminotransferase level as a predictor of intracerebral hemorrhage: Korea medical insurance corporation study.
Topics: Adult; Alanine Transaminase; Aspartic Acid; Blood Pressure; Brain Ischemia; Cerebral Hemorrhage; Fem | 2005 |
Reduced prefrontal N-acetylaspartate in stroke patients with apathy.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Depression; Female; Functional Laterality; Humans; Magnetic | 2005 |
Prediction of cognitive decline after stroke using proton magnetic resonance spectroscopy.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Aspartic Acid; Brain Chemistry; Cognition Disorders; | 2006 |
The glu298asp polymorphism in the nitric oxide synthase 3 gene is associated with the risk of ischemic stroke in two large independent case-control studies.
Topics: Aged; Aspartic Acid; Case-Control Studies; Female; Glutamic Acid; Humans; Integrin alpha2; Interleuk | 2007 |
Prefrontal N-acetylaspartate and poststroke recovery: a longitudinal proton spectroscopy study.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain Ischemia; Creatine; Female; Follow-Up Studies; Functio | 2007 |
Neuroprotective potential of ceftriaxone in in vitro models of stroke.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anti-Bacterial Agents; Aspartic Acid; Ceftriaxone; | 2007 |
The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo.
Topics: Alanine; Animals; Aspartic Acid; Brain Ischemia; Cerebral Arteries; Disease Models, Animal; Gene Exp | 2007 |
COL4A1 mutation in Axenfeld-Rieger anomaly with leukoencephalopathy and stroke.
Topics: Adult; Anterior Eye Segment; Aspartic Acid; Autoantigens; Brain Diseases; Child; Collagen Type IV; E | 2007 |
Relating MRI changes to motor deficit after ischemic stroke by segmentation of functional motor pathways.
Topics: Adult; Aged; Aspartic Acid; Brain Ischemia; Disability Evaluation; Female; Humans; Internal Capsule; | 2000 |
Correlating magnetic resonance imaging markers of axonal injury and demyelination in motor impairment secondary to stroke and multiple sclerosis.
Topics: Adult; Aged; Aspartic Acid; Axons; Female; Functional Laterality; Humans; Internal Capsule; Magnetic | 2000 |
No association between Glu/Asp polymorphism of NOS3 gene and ischemic stroke.
Topics: Adolescent; Aspartic Acid; Brain Ischemia; Child; Child, Preschool; Genetic Linkage; Glutamic Acid; | 2000 |
N-acetylaspartate distribution in proton spectroscopic images of ischemic stroke: relationship to infarct appearance on T2-weighted magnetic resonance imaging.
Topics: Acute Disease; Aspartic Acid; Brain; Brain Ischemia; Cerebral Infarction; Humans; Image Processing, | 2000 |
A comparative assessment of the efficacy and side-effect liability of neuroprotective compounds in experimental stroke.
Topics: Animals; Aspartic Acid; Extracellular Space; Glutamic Acid; Hypoxia-Ischemia, Brain; Male; Mice; Mic | 2001 |
Neurologic course of congenital disorders of glycosylation.
Topics: Aspartic Acid; Brain; Brain Diseases, Metabolic, Inborn; Child; Child, Preschool; Congenital Disorde | 2001 |