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aspartic acid and Soft Tissue Neoplasms

aspartic acid has been researched along with Soft Tissue Neoplasms in 5 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Soft Tissue Neoplasms: Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.

Research Excerpts

ExcerptRelevanceReference
"We conducted parallel phase II trials of cimetidine as a single agent and the combination N-phosphonacetyl-L-aspartate (PALA) plus L-alanosine among 40 previously untreated patients with biopsy-proven, measurable disseminated malignant melanoma."9.06Phase II studies of single-agent cimetidine and the combination N-phosphonacetyl-L-aspartate (NSC-224131) plus L-alanosine (NSC-153353) in advanced malignant melanoma. ( Chang, M; Creagan, ET; Cullinan, SA; Ebbert, L; Mailliard, JA; Morton, RF; Veeder, MH, 1987)
"A total of 21 patients with advanced soft tissue sarcoma enrolled in a phase II trial of 3."6.67A phase II trial of PALA + dipyridamole in patients with advanced soft-tissue sarcoma. ( Baselga, J; Casper, ES; Magill, GB; Markman, M; Ranhosky, A; Smart, TB, 1991)
"We conducted parallel phase II trials of cimetidine as a single agent and the combination N-phosphonacetyl-L-aspartate (PALA) plus L-alanosine among 40 previously untreated patients with biopsy-proven, measurable disseminated malignant melanoma."5.06Phase II studies of single-agent cimetidine and the combination N-phosphonacetyl-L-aspartate (NSC-224131) plus L-alanosine (NSC-153353) in advanced malignant melanoma. ( Chang, M; Creagan, ET; Cullinan, SA; Ebbert, L; Mailliard, JA; Morton, RF; Veeder, MH, 1987)
"A total of 21 patients with advanced soft tissue sarcoma enrolled in a phase II trial of 3."2.67A phase II trial of PALA + dipyridamole in patients with advanced soft-tissue sarcoma. ( Baselga, J; Casper, ES; Magill, GB; Markman, M; Ranhosky, A; Smart, TB, 1991)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bramwell, V1
Van Oosterom, A1
Mouridsen, HT1
Cheix, F1
Somers, R1
Thomas, D2
Rozencweig, M2
Kleeberg, UR1
Mulder, JH1
Rümke, P1
Kurzrock, R1
Yap, BS1
Plager, C1
Papdopoulos, N1
Benjamin, RS1
Valdivieso, M1
Bodey, GP1
Casper, ES1
Baselga, J1
Smart, TB1
Magill, GB1
Markman, M1
Ranhosky, A1
Morton, RF1
Creagan, ET1
Cullinan, SA1
Mailliard, JA1
Ebbert, L1
Veeder, MH1
Chang, M1

Trials

2 trials available for aspartic acid and Soft Tissue Neoplasms

ArticleYear
A phase II trial of PALA + dipyridamole in patients with advanced soft-tissue sarcoma.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Aspartic Acid; Dipyridamole; Drug Evaluation; Drug Therapy, Comb

1991
Phase II studies of single-agent cimetidine and the combination N-phosphonacetyl-L-aspartate (NSC-224131) plus L-alanosine (NSC-153353) in advanced malignant melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:7

    Topics: Alanine; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cimetidine; Drug Evaluation;

1987

Other Studies

3 other studies available for aspartic acid and Soft Tissue Neoplasms

ArticleYear
N-(phosphonacetyl)-L-aspartate (PALA) in advanced soft tissue sarcoma: a phase II trial of the EORTC soft tissue sarcoma group.
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Aspartic Acid; Digestive System; Drug Erup

1982
N-(phosphonacetyl)-L-aspartate (PALA) in advanced malignant melanoma: a phase II trial of the EORTC Malignant Melanoma Cooperative Group.
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Aspartic Acid; Drug Eruptions; Drug Evaluation; Female; Humans;

1982
Phase II evaluation of PALA in patients with refractory metastatic sarcomas.
    American journal of clinical oncology, 1984, Volume: 7, Issue:4

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Aspartic Acid; Bone Neoplasms; Diarrhea; Drug Evaluati

1984