aspartic acid has been researched along with Sleep Apnea, Obstructive in 9 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Univariate ANOVA disclosed significant effects of AHI, age, and the presence or absence of hypertension on the NAA/choline ratio for cerebral white matter (p=0." | 3.71 | Cerebral metabolic impairment in patients with obstructive sleep apnoea: an independent association of obstructive sleep apnoea with white matter change. ( Chen, W; Higami, S; Inoue, Y; Kamba, M; Ogawa, T; Suto, Y, 2001) |
| "Adults with obstructive sleep apnea (OSA) show significant autonomic and neuropsychologic deficits, which may derive from damage to insular regions that serve those functions." | 1.40 | Insular cortex metabolite changes in obstructive sleep apnea. ( Harper, RM; Kumar, R; Macey, PM; Woo, MA; Yadav, SK; Yan-Go, FL, 2014) |
| "Childhood obstructive sleep apnea (OSA) is associated with neuropsychological deficits of memory, learning, and executive function." | 1.33 | Childhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injury. ( Barker, PB; Degaonkar, M; Earley, CJ; Halbower, AC; Mahone, EM; Marcus, CL; Prahme, MC; Smith, PL, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yadav, SK | 1 |
| Kumar, R | 1 |
| Macey, PM | 1 |
| Woo, MA | 1 |
| Yan-Go, FL | 1 |
| Harper, RM | 1 |
| Sarchielli, P | 1 |
| Presciutti, O | 1 |
| Alberti, A | 1 |
| Tarducci, R | 1 |
| Gobbi, G | 1 |
| Galletti, F | 1 |
| Costa, C | 1 |
| Eusebi, P | 1 |
| Calabresi, P | 1 |
| Sharma, SK | 1 |
| Sinha, S | 1 |
| Danishad, KA | 1 |
| Sharma, U | 1 |
| Sharma, H | 1 |
| Mishra, HK | 1 |
| Mishra, H | 1 |
| Kadhiravan, T | 1 |
| Reddy, VV | 1 |
| Sreenivas, V | 1 |
| Jagannathan, NR | 1 |
| Algin, O | 1 |
| Gokalp, G | 1 |
| Ocakoglu, G | 1 |
| Ursavas, A | 1 |
| Taskapilioglu, O | 1 |
| Hakyemez, B | 1 |
| Bartlett, DJ | 1 |
| Rae, C | 1 |
| Thompson, CH | 1 |
| Byth, K | 1 |
| Joffe, DA | 1 |
| Enright, T | 1 |
| Grunstein, RR | 1 |
| Alchanatis, M | 1 |
| Deligiorgis, N | 1 |
| Zias, N | 1 |
| Amfilochiou, A | 1 |
| Gotsis, E | 1 |
| Karakatsani, A | 1 |
| Papadimitriou, A | 1 |
| Halbower, AC | 1 |
| Degaonkar, M | 1 |
| Barker, PB | 1 |
| Earley, CJ | 1 |
| Marcus, CL | 1 |
| Smith, PL | 1 |
| Prahme, MC | 1 |
| Mahone, EM | 1 |
| Tonon, C | 1 |
| Vetrugno, R | 1 |
| Lodi, R | 1 |
| Gallassi, R | 1 |
| Provini, F | 1 |
| Iotti, S | 1 |
| Plazzi, G | 1 |
| Montagna, P | 1 |
| Lugaresi, E | 1 |
| Barbiroli, B | 1 |
| Kamba, M | 1 |
| Inoue, Y | 1 |
| Higami, S | 1 |
| Suto, Y | 1 |
| Ogawa, T | 1 |
| Chen, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Brain Changes in Pediatric Obstructive Sleep Apnea[NCT05368077] | 70 participants (Anticipated) | Interventional | 2022-05-14 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for aspartic acid and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Insular cortex metabolite changes in obstructive sleep apnea.
Topics: Adult; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Cross-Sectional Studies; Female; Humans; I | 2014 |
A 1H magnetic resonance spectroscopy study in patients with obstructive sleep apnea.
Topics: Adult; Aged; Aspartic Acid; Brain Chemistry; Cell Death; Choline; Comorbidity; Creatinine; Female; F | 2008 |
Proton magnetic resonance spectroscopy of brain in obstructive sleep apnoea in north Indian Asian subjects.
Topics: Adult; Analysis of Variance; Anthropometry; Aspartic Acid; Brain; Dipeptides; Female; Humans; India; | 2010 |
Neurochemical-structural changes evaluation of brain in patients with obstructive sleep apnea syndrome.
Topics: Adult; Aged; Aspartic Acid; Brain; Case-Control Studies; Choline; Creatine; Diffusion Magnetic Reson | 2012 |
Hippocampal area metabolites relate to severity and cognitive function in obstructive sleep apnea.
Topics: Adult; Arousal; Aspartic Acid; Cognition Disorders; Electroencephalography; Female; Hippocampus; Hum | 2004 |
Frontal brain lobe impairment in obstructive sleep apnoea: a proton MR spectroscopy study.
Topics: Adult; Analysis of Variance; Aspartic Acid; Choline; Creatine; Humans; Inositol; Magnetic Resonance | 2004 |
Childhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injury.
Topics: Adolescent; Aspartic Acid; Brain Injuries; Case-Control Studies; Cerebral Cortex; Child; Choline; Cr | 2006 |
Proton magnetic resonance spectroscopy study of brain metabolism in obstructive sleep apnoea syndrome before and after continuous positive airway pressure treatment.
Topics: Adult; Arousal; Aspartic Acid; Blood Pressure; Cerebral Cortex; Choline; Continuous Positive Airway | 2007 |
Cerebral metabolic impairment in patients with obstructive sleep apnoea: an independent association of obstructive sleep apnoea with white matter change.
Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Body Mass Index; Brain Chemistry; Cerebral Cortex; | 2001 |