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aspartic acid and Seizures, Febrile

aspartic acid has been researched along with Seizures, Febrile in 4 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Seizures, Febrile: Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784)

Research Excerpts

ExcerptRelevanceReference
"Generalized epilepsy with febrile seizures plus (GEFS+) and severe myoclonic epilepsy of infancy (SMEI) differ in their clinical severity and prognosis even though mutations of the Na(v) 1."1.38Different degrees of loss of function between GEFS+ and SMEI Nav 1.1 missense mutants at the same residue induced by rescuable folding defects. ( Hoshi, A; Ogiwara, I; Sugiura, Y; Ugawa, Y; Yamakawa, K, 2012)
"Generalized epilepsy with febrile seizures plus (GEFS+) is an inherited epileptic syndrome with a marked clinical and genetic heterogeneity."1.33A novel SCN1A mutation associated with severe GEFS+ in a large South American pedigree. ( Arias, W; Bedoya, G; Cabrera, D; Carrizosa, J; Cornejo, W; Franco, C; Pineda-Trujillo, N; Ruíz-Linares, A, 2005)
"An association between complex febrile convulsions and the development of hippocampal atrophy, which is characterized by neuron loss and gliosis, has been suggested but is still controversial."1.30Proton spectroscopy in children with epilepsy and febrile convulsions. ( Holopainen, IE; Komu, ME; Lundbom, NM; Manner, TE; Sillanpää, ML; Sonninen, PH; Valtonen, ME, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sugiura, Y1
Ogiwara, I1
Hoshi, A1
Yamakawa, K1
Ugawa, Y1
Pineda-Trujillo, N1
Carrizosa, J1
Cornejo, W1
Arias, W1
Franco, C1
Cabrera, D1
Bedoya, G1
Ruíz-Linares, A1
Holopainen, IE1
Valtonen, ME1
Komu, ME1
Sonninen, PH1
Manner, TE1
Lundbom, NM1
Sillanpää, ML1
Freeman, JL1
Coleman, LT1
Smith, LJ1
Shield, LK1

Other Studies

4 other studies available for aspartic acid and Seizures, Febrile

ArticleYear
Different degrees of loss of function between GEFS+ and SMEI Nav 1.1 missense mutants at the same residue induced by rescuable folding defects.
    Epilepsia, 2012, Volume: 53, Issue:6

    Topics: Arginine; Aspartic Acid; Biophysics; Cell Line, Transformed; Electric Stimulation; Epilepsies, Myocl

2012
A novel SCN1A mutation associated with severe GEFS+ in a large South American pedigree.
    Seizure, 2005, Volume: 14, Issue:2

    Topics: Adult; Age of Onset; Amino Acid Substitution; Aspartic Acid; Child; Child, Preschool; DNA Mutational

2005
Proton spectroscopy in children with epilepsy and febrile convulsions.
    Pediatric neurology, 1998, Volume: 19, Issue:2

    Topics: Aspartic Acid; Child; Child, Preschool; Choline; Electroencephalography; Epilepsy; Hippocampus; Huma

1998
Hemiconvulsion-hemiplegia-epilepsy syndrome: characteristic early magnetic resonance imaging findings.
    Journal of child neurology, 2002, Volume: 17, Issue:1

    Topics: Aspartic Acid; Brain; Brain Edema; Child, Preschool; Dominance, Cerebral; Female; Follow-Up Studies;

2002