aspartic acid has been researched along with Pregnancy in 261 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aims to investigate the effect of resveratrol on intrahepatic cholestasis of pregnancy (ICP) and its effect on the gut microbiome profiles, thus contributing to the potential therapeutic strategies for ICP." | 8.12 | Resveratrol modulates the gut microbiota of cholestasis in pregnant rats. ( Lei, L; Li, Z; Ling, L; Liu, Y; Shao, Y; Xiong, Z, 2022) |
| "We identified two infants with lethal (type II) osteogenesis imperfecta (OI) who were heterozygous for mutations in the COL1A1 gene that resulted in substitutions of aspartic acid for glycine at position 220 and arginine for glycine at position 664 in the product of one COL1A1 allele in each individual." | 7.69 | Substitutions of aspartic acid for glycine-220 and of arginine for glycine-664 in the triple helix of the pro alpha 1(I) chain of type I procollagen produce lethal osteogenesis imperfecta and disrupt the ability of collagen fibrils to incorporate crystall ( Atkinson, M; Byers, PH; Culbert, AA; Kadler, KE; Lowe, MP; Wallis, GA, 1995) |
| "Pantetheine 4'-phosphate was significantly negatively associated with non-high-density lipoprotein (non-HDL) and TC levels." | 5.91 | Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat offspring. ( Liu, Y; Luo, T; Meng, X; Yu, G; Zhang, J; Zhang, R, 2023) |
| "This study aims to investigate the effect of resveratrol on intrahepatic cholestasis of pregnancy (ICP) and its effect on the gut microbiome profiles, thus contributing to the potential therapeutic strategies for ICP." | 4.12 | Resveratrol modulates the gut microbiota of cholestasis in pregnant rats. ( Lei, L; Li, Z; Ling, L; Liu, Y; Shao, Y; Xiong, Z, 2022) |
| "Prenatal diagnosis of Canavan disease by measuring N-acetylaspartic acid (NAA) in amniotic fluid is reliable and preferred over aspartoacylase enzyme assay especially in populations with unknown mutations." | 3.75 | Reliable prenatal diagnosis of Canavan disease by measuring N-acetylaspartate in amniotic fluid using liquid chromatography tandem mass spectrometry. ( Ahmad, AM; Al-Dirbashi, OY; Al-Nemer, M; Al-Sayed, M; Imtiaz, F; Kurdi, W; Rashed, MS; Tulbah, M, 2009) |
| "We identified two infants with lethal (type II) osteogenesis imperfecta (OI) who were heterozygous for mutations in the COL1A1 gene that resulted in substitutions of aspartic acid for glycine at position 220 and arginine for glycine at position 664 in the product of one COL1A1 allele in each individual." | 3.69 | Substitutions of aspartic acid for glycine-220 and of arginine for glycine-664 in the triple helix of the pro alpha 1(I) chain of type I procollagen produce lethal osteogenesis imperfecta and disrupt the ability of collagen fibrils to incorporate crystall ( Atkinson, M; Byers, PH; Culbert, AA; Kadler, KE; Lowe, MP; Wallis, GA, 1995) |
| "L-Alanosine [L-2-amino-3(N-hydroxy-N-nitrosamino)propionic acid], a tumor-inhibiting agent, induces pregnancy arrest after single or multiple SC or PO administration to rats and hamsters." | 3.67 | Contragestational profile of the tumor-inhibiting agent, L-alanosine, in the rat and the hamster. ( Assandri, A; Barone, D; Galliani, G; Grandi, M; Lancini, GC; Mistrello, G, 1985) |
| " Taking both electrolytes together instead of 2 to 3 h apart from each other, as actually recommended, means a less complicated dosage regimen and probably improves compliance." | 2.68 | Therapeutic availability of iron administered orally as the ferrous gluconate together with magnesium-L-aspartate hydrochloride. ( Classen, HG; Disch, G; Leifert, U; Schumacher, E; Spätling, L, 1996) |
| "There were significantly fewer cases of EPH gestosis in the magnesium group, and no serious side effects of treatment." | 2.66 | [Magnesium substitution in pregnancy. A prospective, randomized double-blind study]. ( Bódis, L; Huhn, E; Kovács, L; Molnár, BG, 1988) |
| "As a result of aspartoacylase deficiency, NAA builds up in extracellular fluids (ECF) and is excreted in urine." | 2.40 | Canavan disease. Analysis of the nature of the metabolic lesions responsible for development of the observed clinical symptoms. ( Baslow, MH; Resnik, TR, 1997) |
| "Canavan disease, spongy degeneration of the brain, is an autosomal recessive disorder with increased prevalence among Ashkenazi Jews." | 2.40 | Canavan disease: diagnosis and molecular analysis. ( Matalon, R, 1997) |
| " However, there is no doubt that these amino acids are toxic to the neonatal mouse at high dose levels." | 2.35 | Absorption, utilization, and safety of aspartic acid. ( Stegink, LD, 1976) |
| "Glycine at 10-14 GW was inversely associated with GDM (adjusted OR [95% CI] per SD increment: 0." | 1.91 | Plasma Amino Acids in Early Pregnancy and Midpregnancy and Their Interplay With Phospholipid Fatty Acids in Association With the Risk of Gestational Diabetes Mellitus: Results From a Longitudinal Prospective Cohort. ( Bremer, AA; Chen, Z; Li, LJ; Lu, R; Pang, WW; Rahman, ML; Tekola-Ayele, F; Tsai, MY; Weir, NL; Wu, J; Yang, J; Zhang, C, 2023) |
| "Children of mothers with gestational diabetes mellitus (GDM) are more prone to acquire type 2 diabetes and obesity as adults." | 1.91 | Oral probiotics increased the proportion of Treg, Tfr, and Breg cells to inhibit the inflammatory response and impede gestational diabetes mellitus. ( Feng, Y; Jie, Q; Liang, W; Qin, J; Wu, W; Yang, D; Zhi, X, 2023) |
| "Pantetheine 4'-phosphate was significantly negatively associated with non-high-density lipoprotein (non-HDL) and TC levels." | 1.91 | Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat offspring. ( Liu, Y; Luo, T; Meng, X; Yu, G; Zhang, J; Zhang, R, 2023) |
| "Lower birth weight was associated with (i) smaller brain sizes, (ii) slightly lower brain temperatures, and (iii) differential metabolite profile changes in specific regions of the brain parenchyma." | 1.42 | In Vivo Detection of Perinatal Brain Metabolite Changes in a Rabbit Model of Intrauterine Growth Restriction (IUGR). ( Carbajo, RJ; González-Tendero, A; Gratacós, E; Illa, M; Muñoz-Moreno, E; Pineda-Lucena, A; Sanz-Cortés, M; Simões, RV, 2015) |
| "The presence of a patent ductus arteriosus (PDA) was the only clinical factor related to NAA ratios." | 1.40 | Diffusion-weighted imaging and magnetic resonance proton spectroscopy following preterm birth. ( Alladi, S; Griffiths, PD; Hart, AR; Paley, MN; Smith, MF; Whitby, EH; Wilkinson, S, 2014) |
| "Bilateral striatal necrosis is usually associated with either endogenous or exogenous toxins, and with poor neurodevelopmental outcomes." | 1.38 | Reversible parainfectious bilateral "striatal necrosis". ( Connolly, DJ; Khan, R; Mordekar, SR; Nandish, S; Rittey, CD, 2012) |
| "Bisphenol A (BPA) has been implicated as an endocrine-disrupting chemical (EDC) due to its ability to mimic the action of endogenous estrogenic hormones." | 1.37 | Developmental and metabolic brain alterations in rats exposed to bisphenol A during gestation and lactation. ( Aubert, ML; Camm, EJ; Darbre, S; Gruetter, R; Hüppi, PS; Kunz, N; Lodygensky, G; Sizonenko, SV; Somm, E, 2011) |
| "Histopathological chorioamnionitis and white matter injury were scored using validated systems." | 1.35 | Effect of chorioamnionitis on brain development and injury in premature newborns. ( Bowen-Roberts, T; Brant, R; Chau, V; McFadden, DE; Miller, SP; Poskitt, KJ; Sargent, MA; Soulikias, W; Synnes, A, 2009) |
| " No mortalities or evidence of adverse effects were observed in SD rats following acute oral administration of 2000mg/kg NAA." | 1.35 | Acute and repeated dose oral toxicity of N-acetyl-l-aspartic acid in Sprague-Dawley rats. ( Amanda Shen, Z; Barnett, JF; Delaney, B; Gannon, S; Maxwell, C; Munley, SA; Powley, CR, 2008) |
| "After prolonged hypoxemia aspartate and glutamate accumulated excessively in the CSF of near-term born lambs." | 1.33 | Excitatory amino acid release and electrocortical brain activity after hypoxemia in near-term lambs. ( Hopman, J; Ruitenbeek, W; van de Bor, M; van Os, S, 2006) |
| "Three of them had fetal alcohol syndrome (FAS), 3 had partial FAS (PFAS), and 4 had alcohol-related neurobehavioral disorder (ARND)." | 1.33 | Brain metabolic alterations in adolescents and young adults with fetal alcohol spectrum disorders. ( Autti-Rämö, I; Fagerlund, A; Heikkinen, S; Korkman, M; Kuusi, T; Lundbom, N; Riley, EP; Timonen, M, 2006) |
| "Two cases of reversible posterior leukoencephalopathy syndrome were examined with proton MR spectroscopic imaging." | 1.31 | Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome. ( Barker, PB; Beauchamp, NJ; Eichler, FS; Wang, P; Wityk, RJ, 2002) |
| " In the parental generation, too, adverse effects of Mg-L were aggravated by Mg-L/Fe-L despite the fact that no iron accumulation occurred." | 1.29 | Potentiation of magnesium-deficiency-induced foetotoxicity by concomitant iron deficiency and its prevention by adequate supply via drinking water. ( Bubeck, J; Classen, HG; Disch, G; Haussecker, H; Spätling, L, 1994) |
| "The cycloleucine block was unaffected by shifts in the holding potential (-60 to +60 mV), and there was no effect of cycloleucine on the reversal potential of the NMDA-evoked current." | 1.28 | Cycloleucine blocks NMDA responses in cultured hippocampal neurones under voltage clamp: antagonism at the strychnine-insensitive glycine receptor. ( Hershkowitz, N; Rogawski, MA, 1989) |
| "Aspartic acid in UA was significantly lower with infusion." | 1.27 | [Effects of maltose infusion on amino acid composition of maternal venous blood and fetal blood in utero]. ( Iwata, M; Nishijima, M, 1983) |
| "This report examines the safety issues related to the nutritive sweetener aspartame, including possible toxic effects of aspartame's component amino acids, aspartic acid and phenylalanine, and its major decomposition products, methanol and diketopiperazine, and the potential synergistic effect of aspartame and dietary carbohydrate on brain neurochemicals." | 1.27 | Aspartame. Review of safety issues. Council on Scientific Affairs. ( , 1985) |
| "Effects of glucose concentration and anoxia upon the metabolite concentrations and rates of glycolysis and respiration have been investigated in the perfused liver of the fetal guinea pig." | 1.26 | Some effects of glucose concentration and anoxia on glycolysis and metabolite concentrations in the perfused liver of fetal guinea pig. ( Faulkner, A; Jones, CT, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 105 (40.23) | 18.7374 |
| 1990's | 51 (19.54) | 18.2507 |
| 2000's | 56 (21.46) | 29.6817 |
| 2010's | 30 (11.49) | 24.3611 |
| 2020's | 19 (7.28) | 2.80 |
| Authors | Studies |
|---|---|
| Uchida, M | 1 |
| Noda, Y | 1 |
| Hasegawa, S | 1 |
| Hida, H | 1 |
| Taniguchi, M | 1 |
| Mouri, A | 2 |
| Yoshimi, A | 1 |
| Nabeshima, T | 2 |
| Yamada, K | 1 |
| Aida, T | 1 |
| Tanaka, K | 1 |
| Ozaki, N | 1 |
| Chen, X | 1 |
| Chen, H | 1 |
| Nie, H | 1 |
| Li, G | 1 |
| Su, J | 1 |
| Cao, X | 2 |
| Cao, Y | 1 |
| Wei, F | 1 |
| Lee, YSL | 1 |
| Gardner, DK | 3 |
| Fang, Q | 1 |
| Liu, J | 1 |
| Chen, L | 1 |
| Chen, Q | 1 |
| Wang, Y | 2 |
| Li, Z | 2 |
| Fu, W | 1 |
| Liu, Y | 3 |
| Li, S | 3 |
| Lyu, G | 1 |
| Yang, H | 1 |
| Yang, Y | 1 |
| Rodrigues, H | 1 |
| Silva, C | 1 |
| Martel, F | 1 |
| Gao, LM | 1 |
| Liu, GY | 1 |
| Wang, HL | 1 |
| Wassie, T | 1 |
| Wu, X | 1 |
| Yin, YL | 1 |
| Lei, L | 1 |
| Ling, L | 1 |
| Xiong, Z | 1 |
| Shao, Y | 2 |
| Iqbal, R | 1 |
| Beigh, SA | 1 |
| Mir, AQ | 1 |
| Shaheen, M | 1 |
| Hussain, SA | 1 |
| Nisar, M | 1 |
| Dar, AA | 1 |
| Yang, J | 1 |
| Wu, J | 1 |
| Tekola-Ayele, F | 1 |
| Li, LJ | 1 |
| Bremer, AA | 1 |
| Lu, R | 1 |
| Rahman, ML | 1 |
| Weir, NL | 1 |
| Pang, WW | 1 |
| Chen, Z | 1 |
| Tsai, MY | 1 |
| Zhang, C | 1 |
| Ma, Y | 1 |
| Song, J | 2 |
| Sun, Z | 1 |
| Zhuo, Y | 1 |
| Zou, X | 1 |
| Jiang, X | 1 |
| Sun, M | 1 |
| Xu, S | 1 |
| Lin, Y | 1 |
| Hua, L | 1 |
| Li, J | 1 |
| Feng, B | 1 |
| Fang, Z | 1 |
| Che, L | 1 |
| Su, AL | 1 |
| Harris, SM | 1 |
| Elkin, ER | 1 |
| Karnovsky, A | 1 |
| Colacino, J | 1 |
| Loch-Caruso, RK | 1 |
| Yang, Q | 1 |
| Deng, Z | 1 |
| Shi, C | 1 |
| Zhuang, G | 1 |
| Hao, H | 1 |
| Cai, Y | 1 |
| Liang, W | 1 |
| Feng, Y | 1 |
| Yang, D | 1 |
| Qin, J | 1 |
| Zhi, X | 1 |
| Wu, W | 1 |
| Jie, Q | 1 |
| Meng, X | 1 |
| Yu, G | 1 |
| Luo, T | 1 |
| Zhang, R | 1 |
| Zhang, J | 1 |
| Pradhan, S | 2 |
| Kapse, K | 2 |
| Jacobs, M | 1 |
| Niforatos-Andescavage, N | 1 |
| Quistorff, JL | 1 |
| Lopez, C | 1 |
| Bannantine, KL | 1 |
| Andersen, NR | 1 |
| Vezina, G | 2 |
| Limperopoulos, C | 4 |
| Graham, AS | 1 |
| Holmes, MJ | 1 |
| Little, F | 1 |
| Dobbels, E | 1 |
| Cotton, MF | 1 |
| Laughton, B | 1 |
| van der Kouwe, A | 1 |
| Meintjes, EM | 1 |
| Robertson, FC | 1 |
| Flaviani, F | 1 |
| Hezelgrave, NL | 1 |
| Kanno, T | 1 |
| Prosdocimi, EM | 1 |
| Chin-Smith, E | 1 |
| Ridout, AE | 1 |
| von Maydell, DK | 1 |
| Mistry, V | 1 |
| Wade, WG | 1 |
| Shennan, AH | 1 |
| Dimitrakopoulou, K | 1 |
| Seed, PT | 1 |
| Mason, AJ | 1 |
| Tribe, RM | 1 |
| Albano, R | 1 |
| Lobner, D | 1 |
| Cathey, A | 1 |
| Ferguson, KK | 1 |
| McElrath, TF | 1 |
| Cantonwine, DE | 1 |
| Pace, G | 1 |
| Alshawabkeh, A | 1 |
| Cordero, JF | 1 |
| Meeker, JD | 1 |
| Basu, SK | 1 |
| McCarter, R | 1 |
| Murnick, J | 1 |
| Chang, T | 1 |
| Hart, AR | 1 |
| Smith, MF | 1 |
| Whitby, EH | 1 |
| Alladi, S | 1 |
| Wilkinson, S | 1 |
| Paley, MN | 1 |
| Griffiths, PD | 1 |
| Kamdi, SP | 1 |
| Palkar, PJ | 1 |
| Robertson, NJ | 1 |
| Thayyil, S | 1 |
| Cady, EB | 1 |
| Raivich, G | 1 |
| Kervern, M | 1 |
| Silvestre de Ferron, B | 1 |
| Alaux-Cantin, S | 1 |
| Fedorenko, O | 1 |
| Antol, J | 1 |
| Naassila, M | 1 |
| Pierrefiche, O | 1 |
| Yan, G | 1 |
| Xuan, Y | 1 |
| Peng, H | 1 |
| Huang, QJ | 1 |
| Wu, R | 1 |
| Xu, H | 1 |
| Simões, RV | 1 |
| Muñoz-Moreno, E | 1 |
| Carbajo, RJ | 1 |
| González-Tendero, A | 1 |
| Illa, M | 1 |
| Sanz-Cortés, M | 1 |
| Pineda-Lucena, A | 1 |
| Gratacós, E | 1 |
| Li, Q | 1 |
| Leung, YO | 1 |
| Zhou, I | 1 |
| Ho, LC | 1 |
| Kong, W | 1 |
| Basil, P | 1 |
| Wei, R | 1 |
| Lam, S | 1 |
| Zhang, X | 1 |
| Law, AC | 1 |
| Chua, SE | 1 |
| Sham, PC | 1 |
| Wu, EX | 1 |
| McAlonan, GM | 1 |
| Evangelou, IE | 1 |
| du Plessis, AJ | 2 |
| Noeske, R | 1 |
| Vernon, AC | 1 |
| So, PW | 1 |
| Lythgoe, DJ | 1 |
| Chege, W | 1 |
| Cooper, JD | 1 |
| Williams, SC | 1 |
| Kapur, S | 1 |
| Yamaguchi, Y | 1 |
| Yamamoto, K | 1 |
| Sato, Y | 1 |
| Inoue, S | 1 |
| Morinaga, T | 1 |
| Hirano, E | 1 |
| Adams Waldorf, KM | 1 |
| Stencel-Baerenwald, JE | 1 |
| Kapur, RP | 1 |
| Studholme, C | 1 |
| Boldenow, E | 1 |
| Vornhagen, J | 1 |
| Baldessari, A | 1 |
| Dighe, MK | 1 |
| Thiel, J | 1 |
| Merillat, S | 1 |
| Armistead, B | 1 |
| Tisoncik-Go, J | 1 |
| Green, RR | 1 |
| Davis, MA | 1 |
| Dewey, EC | 1 |
| Fairgrieve, MR | 1 |
| Gatenby, JC | 1 |
| Richards, T | 1 |
| Garden, GA | 1 |
| Diamond, MS | 1 |
| Juul, SE | 1 |
| Grant, RF | 1 |
| Kuller, L | 1 |
| Shaw, DW | 1 |
| Ogle, J | 1 |
| Gough, GM | 1 |
| Lee, W | 1 |
| English, C | 1 |
| Hevner, RF | 1 |
| Dobyns, WB | 1 |
| Gale, M | 1 |
| Rajagopal, L | 1 |
| Faserl, K | 1 |
| Sarg, B | 1 |
| Maurer, V | 1 |
| Lindner, HH | 1 |
| O'Leary-Moore, SK | 1 |
| McMechan, AP | 1 |
| Galloway, MP | 1 |
| Hannigan, JH | 1 |
| Teng, GQ | 1 |
| Zhao, X | 1 |
| Lees-Miller, JP | 1 |
| Quinn, FR | 1 |
| Li, P | 1 |
| Rancourt, DE | 1 |
| London, B | 1 |
| Cross, JC | 1 |
| Duff, HJ | 1 |
| Malek, A | 1 |
| Leiser, R | 1 |
| Mitchell, M | 1 |
| Cashman, KS | 1 |
| Thompson, JG | 1 |
| Lane, M | 2 |
| Miura, K | 1 |
| Sekine, T | 1 |
| Iida, A | 1 |
| Takahashi, K | 2 |
| Igarashi, T | 1 |
| Al-Dirbashi, OY | 1 |
| Kurdi, W | 1 |
| Imtiaz, F | 1 |
| Ahmad, AM | 1 |
| Al-Sayed, M | 1 |
| Tulbah, M | 1 |
| Al-Nemer, M | 1 |
| Rashed, MS | 1 |
| DeSilva, TM | 1 |
| Kabakov, AY | 1 |
| Goldhoff, PE | 1 |
| Volpe, JJ | 1 |
| Rosenberg, PA | 1 |
| Chau, V | 1 |
| Poskitt, KJ | 1 |
| McFadden, DE | 1 |
| Bowen-Roberts, T | 1 |
| Synnes, A | 1 |
| Brant, R | 1 |
| Sargent, MA | 1 |
| Soulikias, W | 1 |
| Miller, SP | 1 |
| Nishizawa, H | 1 |
| Pryor-Koishi, K | 1 |
| Suzuki, M | 1 |
| Kato, T | 2 |
| Sekiya, T | 1 |
| Tada, S | 1 |
| Kurahashi, H | 1 |
| Udagawa, Y | 1 |
| Carou, ME | 1 |
| Szwarcfarb, B | 2 |
| Deguiz, ML | 1 |
| Reynoso, R | 3 |
| Carbone, S | 3 |
| Moguilevsky, JA | 3 |
| Scacchi, P | 3 |
| Ponzo, OJ | 2 |
| Tworetzky, W | 1 |
| McElhinney, DB | 1 |
| Newburger, JW | 1 |
| Brown, DW | 1 |
| Robertson, RL | 1 |
| Guizard, N | 1 |
| McGrath, E | 1 |
| Geva, J | 1 |
| Annese, D | 1 |
| Dunbar-Masterson, C | 1 |
| Trainor, B | 1 |
| Laussen, PC | 1 |
| Ponzo, O | 1 |
| Cardoso, N | 2 |
| Deguiz, L | 1 |
| Sikorska, H | 1 |
| Cianciara, J | 1 |
| Wiercińska-Drapało, A | 1 |
| Girard, N | 2 |
| Kunz, N | 1 |
| Camm, EJ | 1 |
| Somm, E | 1 |
| Lodygensky, G | 1 |
| Darbre, S | 1 |
| Aubert, ML | 1 |
| Hüppi, PS | 2 |
| Sizonenko, SV | 1 |
| Gruetter, R | 3 |
| Lu, L | 1 |
| Mamiya, T | 1 |
| Lu, P | 1 |
| Toriumi, K | 1 |
| Hiramatsu, M | 1 |
| Zou, LB | 1 |
| Kwan, TK | 1 |
| Falk, MC | 1 |
| Briz, V | 1 |
| Suñol, C | 1 |
| Duszczyk-Budhathoki, M | 1 |
| Olczak, M | 1 |
| Lehner, M | 1 |
| Majewska, MD | 1 |
| Samaniego, YA | 1 |
| Cutrera, R | 1 |
| Nandish, S | 1 |
| Khan, R | 1 |
| Connolly, DJ | 1 |
| Rittey, CD | 1 |
| Mordekar, SR | 1 |
| Van Kooij, BJ | 1 |
| Benders, MJ | 1 |
| Anbeek, P | 1 |
| Van Haastert, IC | 1 |
| De Vries, LS | 1 |
| Groenendaal, F | 1 |
| McEwen, AM | 1 |
| Burgess, DT | 1 |
| Hanstock, CC | 1 |
| Seres, P | 1 |
| Khalili, P | 1 |
| Newman, SC | 1 |
| Baker, GB | 1 |
| Mitchell, ND | 1 |
| Khudabux-Der, J | 1 |
| Allen, PS | 1 |
| LeMelledo, JM | 1 |
| Berger-Kulemann, V | 1 |
| Brugger, PC | 1 |
| Pugash, D | 1 |
| Krssak, M | 1 |
| Weber, M | 1 |
| Wielandner, A | 1 |
| Prayer, D | 1 |
| Llorente-Folch, I | 1 |
| Sahún, I | 1 |
| Contreras, L | 1 |
| Casarejos, MJ | 1 |
| Grau, JM | 1 |
| Saheki, T | 1 |
| Mena, MA | 1 |
| Satrústegui, J | 1 |
| Dierssen, M | 1 |
| Pardo, B | 1 |
| Bertolino, A | 1 |
| Roffman, JL | 1 |
| Lipska, BK | 1 |
| van Gelderen, P | 1 |
| Olson, A | 1 |
| Weinberger, DR | 1 |
| Changtrakun, Y | 1 |
| Fucharoen, S | 1 |
| Ayukarn, K | 1 |
| Siriratmanawong, N | 1 |
| Fucharoen, G | 1 |
| Sanchaisuriya, K | 1 |
| Lorenz, E | 1 |
| Hallman, M | 1 |
| Marttila, R | 1 |
| Haataja, R | 1 |
| Schwartz, DA | 1 |
| Kok, RD | 2 |
| van den Berg, PP | 2 |
| van den Bergh, AJ | 1 |
| Nijland, R | 1 |
| Heerschap, A | 2 |
| Kreis, R | 1 |
| Hofmann, L | 1 |
| Kuhlmann, B | 1 |
| Boesch, C | 1 |
| Bossi, E | 1 |
| Rutherford, JM | 1 |
| Moody, A | 1 |
| Crawshaw, S | 1 |
| Rubin, PC | 1 |
| Häkli, T | 1 |
| Romppanen, EL | 1 |
| Hiltunen, M | 1 |
| Helisalmi, S | 1 |
| Punnonen, K | 1 |
| Heinonen, S | 1 |
| Thomas, JL | 1 |
| Duax, WL | 1 |
| Addlagatta, A | 1 |
| Brandt, S | 1 |
| Fuller, RR | 1 |
| Norris, W | 1 |
| Celik, O | 1 |
| Hascalik, S | 1 |
| Yoshimura, T | 2 |
| Chowdhury, FA | 1 |
| Yoshimura, M | 2 |
| Okamura, H | 2 |
| MISITI, D | 1 |
| ROSNATI, V | 1 |
| BIGNAMI, G | 1 |
| BOVET-NITTI, F | 1 |
| BOVET, D | 1 |
| YAKUSHIJI, M | 1 |
| YAMASHITA, E | 1 |
| ISAYAMA, Y | 1 |
| Rao, R | 2 |
| Tkac, I | 2 |
| Townsend, EL | 1 |
| Georgieff, MK | 2 |
| Chen, CP | 1 |
| Lin, SP | 1 |
| Tzen, CY | 1 |
| Tsai, FJ | 1 |
| Hwu, WL | 1 |
| Wang, W | 1 |
| Harte, MK | 1 |
| Powell, SB | 1 |
| Reynolds, LM | 1 |
| Swerdlow, NR | 1 |
| Geyer, MA | 1 |
| Reynolds, GP | 1 |
| Olney, JW | 2 |
| Hillermann, R | 1 |
| Carelse, K | 1 |
| Gebhardt, GS | 1 |
| Raman, L | 1 |
| Ennis, K | 1 |
| Repiso, A | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Iron Bisglycinate Chelate or Ferrous Fumarate in Treatment of Iron Deficiency Anemia in Pregnant Women[NCT03378791] | Phase 3 | 120 participants (Actual) | Interventional | 2015-12-31 | Completed | ||
| Optimising the Duration of Cooling Therapy in Mild Neonatal Encephalopathy[NCT03409770] | 140 participants (Anticipated) | Interventional | 2019-10-10 | Active, not recruiting | |||
| Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior[NCT05767385] | Phase 2/Phase 3 | 150 participants (Anticipated) | Interventional | 2021-12-17 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for aspartic acid and Pregnancy
| Article | Year |
|---|---|
Magnetic resonance spectroscopy biomarkers in term perinatal asphyxial encephalopathy: from neuropathological correlates to future clinical applications.
Topics: Animals; Animals, Newborn; Aspartic Acid; Asphyxia Neonatorum; Biomarkers; Choline; Creatine; Diseas | 2014 |
[Physiological functions of L-ornithine and L-aspartate in the body and the efficacy of administration of L-ornithine-L-aspartate in conditions of relative deficiency].
Topics: Animals; Aspartic Acid; Disease Models, Animal; Female; Humans; Ornithine; Physical Exertion; Pregna | 2010 |
[Magnetic resonance spectroscopy for cerebral imaging].
Topics: Apoptosis; Aspartic Acid; Asphyxia Neonatorum; Biomarkers, Tumor; Brain; Brain Diseases; Brain Disea | 2010 |
Excitatory neurotoxins as food additives: an evaluation of risk.
Topics: Adult; Age Factors; Aspartame; Aspartic Acid; Blood-Brain Barrier; Child; Cysteine; Dietary Suppleme | 1981 |
Canavan disease. Analysis of the nature of the metabolic lesions responsible for development of the observed clinical symptoms.
Topics: Amidohydrolases; Animals; Aspartic Acid; Canavan Disease; Central Nervous System; Female; Fetal Dise | 1997 |
Canavan disease: diagnosis and molecular analysis.
Topics: Amidohydrolases; Aspartic Acid; Canavan Disease; Cloning, Molecular; Diagnosis, Differential; Female | 1997 |
Canavan disease: a review of recent developments.
Topics: Amidohydrolases; Aspartic Acid; Canavan Disease; Female; Genetic Therapy; Humans; Infant; Infant, Ne | 2001 |
Absorption, utilization, and safety of aspartic acid.
Topics: Animals; Aspartic Acid; Digestion; Female; Fetus; Haplorhini; Humans; Infant, Newborn; Intestinal Ab | 1976 |
Use of aspartame in pregnancy.
Topics: Aspartame; Aspartic Acid; Digestion; Dipeptides; Female; Fetus; Humans; Methanol; Phenylalanine; Pre | 1985 |
Isozymes of aspartate aminotransferase in tissues and blood of man.
Topics: Acute Disease; Adult; Aging; Alpha-Globulins; Animals; Aspartate Aminotransferases; Aspartic Acid; B | 1966 |
Some polypeptides influencing gastric-acid secretion.
Topics: Amides; Animals; Aspartic Acid; Cattle; Chemical Phenomena; Chemistry; Cysteine; Dogs; Female; Gastr | 1970 |
8 trials available for aspartic acid and Pregnancy
| Article | Year |
|---|---|
Mechanism of Guilu Erxian ointment based on targeted metabolomics in intervening
Topics: alpha-Linolenic Acid; Aspartic Acid; Embryo Transfer; Female; Fertilization in Vitro; Humans; Infert | 2023 |
Efficacy and safety of ferrous asparto glycinate in the management of iron deficiency anaemia in pregnant women.
Topics: Adult; Anemia, Iron-Deficiency; Ascorbic Acid; Aspartic Acid; Double-Blind Method; Female; Ferritins | 2015 |
Brain metabolite composition during early human brain development as measured by quantitative in vivo 1H magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain; Brain Chemistry; Choline; Embryonic and Fetal Development; Female; Gestational | 2002 |
Prognostic value of 1H-MRS in neonatal encephalopathy.
Topics: Apgar Score; Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Choline; Creatine; Creatinine; Femal | 2006 |
Vitamin B supplementation for leg cramps during pregnancy.
Topics: Aspartic Acid; Calcium Carbonate; Drug Therapy, Combination; Female; Humans; Leg; Muscle Cramp; Preg | 2006 |
Therapeutic availability of iron administered orally as the ferrous gluconate together with magnesium-L-aspartate hydrochloride.
Topics: Administration, Oral; Adult; Aged; Animals; Aspartic Acid; Biological Availability; Diet; Female; Fe | 1996 |
[Magnesium, calcium, hemoglobin, hematocrit, estriol and human placental lactogen with magnesium substitution in pregnancy].
Topics: Aspartic Acid; Calcium; Double-Blind Method; Estriol; Female; Hematocrit; Hemoglobinometry; Humans; | 1990 |
[Magnesium substitution in pregnancy. A prospective, randomized double-blind study].
Topics: Aspartic Acid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant, Newborn; Magne | 1988 |
242 other studies available for aspartic acid and Pregnancy
| Article | Year |
|---|---|
Early postnatal inhibition of GLAST causes abnormalities of psychobehaviors and neuronal morphology in adult mice.
Topics: Animals; Animals, Newborn; Aspartic Acid; Excitatory Amino Acid Transporter 1; Female; Injections, I | 2021 |
Amniotic fluid metabolomic and lipidomic alterations associated with hemoglobin Bart's diseases.
Topics: alpha-Thalassemia; Amniotic Fluid; Aspartic Acid; Biomarkers; Female; Glutamates; Hemoglobins, Abnor | 2021 |
Early cleaving embryos result in blastocysts with increased aspartate and glucose consumption, which exhibit different metabolic gene expression that persists in placental and fetal tissues.
Topics: Animals; Aspartic Acid; Blastocyst; Cleavage Stage, Ovum; Embryo Culture Techniques; Embryo Implanta | 2021 |
Taurine supplementation improves hippocampal metabolism in immature rats with intrauterine growth restriction (IUGR) through protecting neurons and reducing gliosis.
Topics: Animals; Aspartic Acid; Choline; Creatine; Dietary Supplements; Female; Fetal Growth Retardation; Gl | 2022 |
Metabolic characterization of amniotic fluid of fetuses with isolated choroid plexus cyst.
Topics: Amniotic Fluid; Arginine; Aspartic Acid; Choroid Plexus; Citrulline; Coenzyme A; Cysts; Ethanolamine | 2022 |
The effects of aspartame on the HTR8/SVneo extravillous trophoblast cell line.
Topics: Aspartame; Aspartic Acid; Cell Line; Cell Movement; Female; Glucose; Humans; Methanol; Phenylalanine | 2022 |
Impact of dietary supplementation with N-carbamoyl-aspartic acid on serum metabolites and intestinal microflora of sows.
Topics: Animal Feed; Animals; Arginine; Aspartic Acid; Birth Weight; Colostrum; Diet; Dietary Supplements; F | 2023 |
Resveratrol modulates the gut microbiota of cholestasis in pregnant rats.
Topics: Alanine; Alanine Transaminase; Animals; Aspartic Acid; Bile Acids and Salts; Cholestasis; Cholestasi | 2022 |
Evaluation of metabolic and oxidative profile in ovine pregnancy toxemia and to determine their association with diagnosis and prognosis of disease.
Topics: 3-Hydroxybutyric Acid; Albumins; Animals; Aspartic Acid; Butyric Acid; Calcium; Catalase; Cholestero | 2022 |
Plasma Amino Acids in Early Pregnancy and Midpregnancy and Their Interplay With Phospholipid Fatty Acids in Association With the Risk of Gestational Diabetes Mellitus: Results From a Longitudinal Prospective Cohort.
Topics: Alanine; Amines; Amino Acids; Aspartic Acid; Diabetes, Gestational; Fatty Acids; Female; Glutamates; | 2023 |
Standardized ileal digestibility of amino acids in cottonseed meal fed to pregnant and non-pregnant sows.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Cotton | 2023 |
Trichloroethylene Metabolite
Topics: Amino Acids; Aspartic Acid; Colforsin; Cysteine; Female; Humans; Matrix Metalloproteinase 2; Oleic A | 2023 |
Discrimination of blood metabolomics profiles in neonates with idiopathic polyhydramnios.
Topics: Alanine; Asparagine; Aspartic Acid; Cesarean Section; Child; Chromatography, Liquid; Female; Glutama | 2023 |
Oral probiotics increased the proportion of Treg, Tfr, and Breg cells to inhibit the inflammatory response and impede gestational diabetes mellitus.
Topics: Animals; Asparagine; Aspartic Acid; B-Lymphocytes, Regulatory; Diabetes Mellitus, Type 2; Diabetes, | 2023 |
Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat offspring.
Topics: Alanine; Animals; Aspartic Acid; Cytochrome P-450 Enzyme System; Female; Gene Expression Profiling; | 2023 |
Non-invasive measurement of biochemical profiles in the healthy fetal brain.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Fetal Development; Gestational Age; Humans; | 2020 |
MRS suggests multi-regional inflammation and white matter axonal damage at 11 years following perinatal HIV infection.
Topics: Anti-Retroviral Agents; Aspartic Acid; Child; Creatine; Female; HIV Infections; Humans; Inflammation | 2020 |
Cervicovaginal microbiota and metabolome predict preterm birth risk in an ethnically diverse cohort.
Topics: Adult; Aspartic Acid; Calcium; Case-Control Studies; Cervix Uteri; Female; Glucose; Humans; Infant, | 2021 |
Transport of BMAA into Neurons and Astrocytes by System x
Topics: Amino Acid Transport Systems; Amino Acids, Diamino; Animals; Aspartic Acid; Astrocytes; Carbon Isoto | 2018 |
Distribution and predictors of urinary polycyclic aromatic hydrocarbon metabolites in two pregnancy cohort studies.
Topics: Adult; Aspartic Acid; Biomarkers; Boston; Cohort Studies; Environmental Monitoring; Environmental Po | 2018 |
Third Trimester Cerebellar Metabolite Concentrations are Decreased in Very Premature Infants with Structural Brain Injury.
Topics: Aspartic Acid; Brain; Brain Injuries; Cerebellum; Choline; Creatine; Female; Gestational Age; Gray M | 2019 |
Diffusion-weighted imaging and magnetic resonance proton spectroscopy following preterm birth.
Topics: Abnormalities, Multiple; Aspartic Acid; Brain; Brain Chemistry; Brain Mapping; Cohort Studies; Devel | 2014 |
Aberrant NMDA-dependent LTD after perinatal ethanol exposure in young adult rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Central Nervous System Depressants; El | 2015 |
Chronic social isolation decreases glutamate and glutamine levels and induces oxidative stress in the rat hippocampus.
Topics: Animals; Aspartic Acid; Catalase; Cerebral Cortex; Energy Metabolism; Female; Glutamic Acid; Glutami | 2015 |
In Vivo Detection of Perinatal Brain Metabolite Changes in a Rabbit Model of Intrauterine Growth Restriction (IUGR).
Topics: Animals; Animals, Newborn; Aspartic Acid; Biomarkers; Birth Weight; Brain; Cerebral Cortex; Corpus S | 2015 |
Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model.
Topics: Animals; Aspartic Acid; Behavior, Animal; Creatine; Diet, High-Fat; Dietary Supplements; Fatty Acids | 2015 |
Elucidating Metabolic Maturation in the Healthy Fetal Brain Using 1H-MR Spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Fetal Development; Fetus; Gestational Age; H | 2016 |
Longitudinal in vivo maturational changes of metabolites in the prefrontal cortex of rats exposed to polyinosinic-polycytidylic acid in utero.
Topics: Age Factors; Animals; Aspartic Acid; Female; Gestational Age; Glutamic Acid; Glutathione; Interferon | 2015 |
Combination of aspartic acid and glutamic acid inhibits tumor cell proliferation.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; | 2016 |
Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate.
Topics: Animals; Aspartic Acid; Brain; Choline; Creatine; Echoencephalography; Female; Fetus; Glutamic Acid; | 2016 |
Exploiting charge differences for the analysis of challenging post-translational modifications by capillary electrophoresis-mass spectrometry.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Citrulline; Electrophoresis, Capillary; Female; Hist | 2017 |
Neonatal alcohol-induced region-dependent changes in rat brain neurochemistry measured by high-resolution magnetic resonance spectroscopy.
Topics: Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Body Weight; Cerebellum; Cerebrum; Choline; E | 2008 |
Homozygous missense N629D hERG (KCNH2) potassium channel mutation causes developmental defects in the right ventricle and its outflow tract and embryonic lethality.
Topics: Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Cardiac Output; ERG1 Potassium Channel; | 2008 |
Influence of the magnesium aspartate hydrochloride administration to the maternal circuit on the aspartate concentration of the fetal circuit under in vitro perfusion of human placenta.
Topics: Aminoisobutyric Acids; Aspartic Acid; Female; Fetus; Humans; In Vitro Techniques; Maternal-Fetal Exc | 2009 |
Disruption of mitochondrial malate-aspartate shuttle activity in mouse blastocysts impairs viability and fetal growth.
Topics: Aminooxyacetic Acid; Animals; Aspartate Aminotransferase, Cytoplasmic; Aspartic Acid; Biological Tra | 2009 |
Salt-losing nephrogenic diabetes insipidus caused by fetal exposure to angiotensin receptor blocker.
Topics: Angiotensin II Type 1 Receptor Blockers; Arginine Vasopressin; Aspartic Acid; Child; Child, Preschoo | 2009 |
Reliable prenatal diagnosis of Canavan disease by measuring N-acetylaspartate in amniotic fluid using liquid chromatography tandem mass spectrometry.
Topics: Amidohydrolases; Amniotic Fluid; Aspartic Acid; Canavan Disease; Case-Control Studies; Chromatograph | 2009 |
Regulation of glutamate transport in developing rat oligodendrocytes.
Topics: Animals; Animals, Newborn; Aspartic Acid; Benzodiazepines; Bicuculline; Brain; Cells, Cultured; Exci | 2009 |
Effect of chorioamnionitis on brain development and injury in premature newborns.
Topics: Anisotropy; Aspartic Acid; Brain; Brain Diseases; Choline; Chorioamnionitis; Diffusion Magnetic Reso | 2009 |
Analysis of nitric oxide metabolism as a placental or maternal factor underlying the etiology of pre-eclampsia.
Topics: Adult; Aspartic Acid; Case-Control Studies; Cyclic GMP; Female; Gestational Age; Glutamic Acid; Huma | 2009 |
Impact of 4-methylbenzylidene-camphor (4-MBC) during embryonic and fetal development in the neuroendocrine regulation of testicular axis in prepubertal and peripubertal male rats.
Topics: Analysis of Variance; Animals; Aspartic Acid; Camphor; Chromatography, High Pressure Liquid; Dose-Re | 2009 |
Brain volume and metabolism in fetuses with congenital heart disease: evaluation with quantitative magnetic resonance imaging and spectroscopy.
Topics: Aspartic Acid; Brain; Choline; Female; Gestational Age; Heart Defects, Congenital; Humans; Imaging, | 2010 |
Impact of gestational and lactational phthalate exposure on hypothalamic content of amino acid neurotransmitters and FSH secretion in peripubertal male rats.
Topics: Amino Acids; Animals; Aspartic Acid; Diethylhexyl Phthalate; Female; Follicle Stimulating Hormone; g | 2010 |
Developmental and metabolic brain alterations in rats exposed to bisphenol A during gestation and lactation.
Topics: Animals; Aspartic Acid; Benzhydryl Compounds; Brain; Endocrine Disruptors; Energy Metabolism; Estrog | 2011 |
Prenatal exposure to PCP produces behavioral deficits accompanied by the overexpression of GLAST in the prefrontal cortex of postpubertal mice.
Topics: Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Behavioral Symptoms; Body Weight; Do | 2011 |
Second pregnancy outcome in a patient with Gitelman syndrome without the use of parenteral electrolyte supplementation.
Topics: Adult; Aspartic Acid; Cesarean Section; Diabetes, Gestational; Electrolytes; Female; Gitelman Syndro | 2011 |
Homeostatic regulation of glutamate neurotransmission in primary neuronal cultures.
Topics: Amino Acid Transport System X-AG; Aniline Compounds; Animals; Aspartic Acid; Biological Transport, A | 2011 |
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate.
Topics: Animals; Animals, Newborn; Aspartic Acid; Chromatography, High Pressure Liquid; Dehydroepiandrostero | 2012 |
Different effects by sex on hypothalamic-pituitary axis of prepubertal offspring rats produced by in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP).
Topics: Animals; Aspartic Acid; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Female; Follicle S | 2012 |
Reversible parainfectious bilateral "striatal necrosis".
Topics: Aspartic Acid; Child, Preschool; Corpus Striatum; Encephalomyelitis; Female; Functional Laterality; | 2012 |
Cerebellar volume and proton magnetic resonance spectroscopy at term, and neurodevelopment at 2 years of age in preterm infants.
Topics: Aspartic Acid; Brain Mapping; Cerebellum; Child, Preschool; Choline; Cognition Disorders; Developmen | 2012 |
Increased glutamate levels in the medial prefrontal cortex in patients with postpartum depression.
Topics: Adult; Aspartic Acid; Case-Control Studies; Creatine; Depression, Postpartum; Female; Glutamic Acid; | 2012 |
MR spectroscopy of the fetal brain: is it possible without sedation?
Topics: Aspartic Acid; Brain; Choline; Conscious Sedation; Creatine; Female; Fetal Diseases; Fetal Growth Re | 2013 |
AGC1-malate aspartate shuttle activity is critical for dopamine handling in the nigrostriatal pathway.
Topics: Amino Acid Transport Systems, Acidic; Animals; Antiporters; Aspartic Acid; Corpus Striatum; Dopamine | 2013 |
Reduced N-acetylaspartate in prefrontal cortex of adult rats with neonatal hippocampal damage.
Topics: Age Factors; Aging; Animals; Animals, Newborn; Aspartic Acid; Female; Hippocampus; Male; Motor Activ | 2002 |
Compound heterozygosity for Hb Korle-Bu (beta(73); Asp-Asn) and Hb E (beta(26); Glu-Lys) with a 3.7-kb deletional alpha-thalassemia in Thai patients.
Topics: Adolescent; Adult; Aged; alpha-Thalassemia; Asparagine; Aspartic Acid; Base Sequence; Chromosome Seg | 2002 |
Association between the Asp299Gly polymorphisms in the Toll-like receptor 4 and premature births in the Finnish population.
Topics: Aspartic Acid; Drosophila Proteins; Endotoxins; Female; Finland; Gene Frequency; Gestational Age; Gl | 2002 |
Maturation of the human fetal brain as observed by 1H MR spectroscopy.
Topics: Aspartic Acid; Brain; Choline; Creatine; Dipeptides; Female; Fetus; Gestational Age; Humans; Inosito | 2002 |
Magnetic resonance spectroscopy in pre-eclampsia: evidence of cerebral ischaemia.
Topics: Adolescent; Adult; Aspartic Acid; Brain Ischemia; Cerebral Arteries; Constriction, Pathologic; Femal | 2003 |
Endothelial nitric oxide synthase polymorphism in preeclampsia.
Topics: Adult; Aspartic Acid; Female; Finland; Genetic Predisposition to Disease; Genotype; Glutamic Acid; H | 2003 |
Antenatal proton MR spectroscopy of the human brain in vivo.
Topics: Aspartic Acid; Brain; Choline; Creatine; Female; Fetus; Gestational Age; Humans; Inositol; Magnetic | 2003 |
Structure/function relationships responsible for coenzyme specificity and the isomerase activity of human type 1 3 beta-hydroxysteroid dehydrogenase/isomerase.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Aspartic Acid; Coenzymes; Female; Humans; Ki | 2003 |
Reversible posterior leukoencephalopathy in eclampsia.
Topics: Adult; Aspartic Acid; Cerebral Arterial Diseases; Choline; Creatine; Female; Humans; Inositol; Magne | 2003 |
Genetic and environmental contributions to severe preeclampsia: lack of association with the endothelial nitric oxide synthase Glu298Asp variant in a developing country.
Topics: Adult; Aspartic Acid; Bangladesh; Birth Weight; Developing Countries; Environment; Female; Gene Freq | 2003 |
EFFECTS OF D,1-3-PHTHALIMIDOGLUTARIMIDE AND N-PHTHALYL-D,L-ASPARTIMIDE ON RAT PREGNANCY.
Topics: Abnormalities, Drug-Induced; Animals; Aspartic Acid; Female; Humans; Imides; Pharmacology; Phthalic | 1963 |
[ON A TRIAL OF L-ASPARTIC ACID-K AND MG SALT IN THE FIELD OF GYNECOLOGY].
Topics: Aspartic Acid; Drug Therapy; Female; Gynecology; Humans; Hyperemesis Gravidarum; Nausea; Pregnancy; | 1964 |
Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus.
Topics: Aging; Animals; Aspartic Acid; Body Weight; Brain; Brain Chemistry; Creatine; Ethanolamines; Female; | 2003 |
Detection of a homozygous D645E mutation of the acid alpha-glucosidase gene and glycogen deposition in tissues in a second-trimester fetus with infantile glycogen storage disease type II.
Topics: Adult; alpha-Glucosidases; Aspartic Acid; Female; Glutamic Acid; Glycogen; Glycogen Storage Disease | 2004 |
Reduced N-acetylaspartate in the temporal cortex of rats reared in isolation.
Topics: Animals; Animals, Newborn; Aspartic Acid; Brain Chemistry; Chromatography, High Pressure Liquid; Fem | 2004 |
Mitochondrial malate-aspartate shuttle regulates mouse embryo nutrient consumption.
Topics: Animals; Aspartic Acid; Biological Transport; Embryo, Mammalian; Embryonic Development; Female; Mala | 2005 |
The Glu298Asp variant of the endothelial nitric oxide synthase gene is associated with an increased risk for abruptio placentae in pre-eclampsia.
Topics: Abruptio Placentae; Adolescent; Adult; Aspartic Acid; Case-Control Studies; Female; Gene Frequency; | 2005 |
In vivo effect of chronic hypoxia on the neurochemical profile of the developing rat hippocampus.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Body Weight; Brain Chem | 2005 |
New haplotype for the Glu104Asp mutation in triose-phosphate isomerase deficiency and prenatal diagnosis in a Spanish family.
Topics: Aspartic Acid; CD4 Antigens; DNA Restriction Enzymes; Evolution, Molecular; Family Health; Female; G | 2005 |
Effects of prenatal paraquat and mancozeb exposure on amino acid synaptic transmission in developing mouse cerebellar cortex.
Topics: Animals; Aspartic Acid; Cerebellar Cortex; Disease Models, Animal; Down-Regulation; Female; Fungicid | 2005 |
Excitatory amino acid release and electrocortical brain activity after hypoxemia in near-term lambs.
Topics: Animals; Animals, Newborn; Aspartic Acid; Blood Glucose; Brain; Electroencephalography; Female; Gest | 2006 |
Cortical excitatory amino acid release and cell function during hypotension in near-term born lambs.
Topics: Animals; Animals, Newborn; Aspartic Acid; Brain Mapping; Cerebral Cortex; Excitatory Amino Acids; Ex | 2006 |
The Duarte (N314D) variant in the GALT gene has no effect on in vitro fertilization outcome.
Topics: Adult; Arginine; Asparagine; Aspartic Acid; Case-Control Studies; Female; Fertilization; Fertilizati | 2006 |
Deducing the transmembrane domain organization of presenilin-1 in gamma-secretase by cysteine disulfide cross-linking.
Topics: Amino Acid Sequence; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid; Aspartic Acid End | 2006 |
Assessment of normal fetal brain maturation in utero by proton magnetic resonance spectroscopy.
Topics: Aging; Algorithms; Aspartic Acid; Brain; Brain Chemistry; Female; Fetal Development; Gestational Age | 2006 |
Chronic intermittent but not constant hypoxia decreases NAA/Cr ratios in neonatal mouse hippocampus and thalamus.
Topics: Animals; Animals, Newborn; Aspartic Acid; Creatine; Female; Hippocampus; Hypoxia, Brain; Magnetic Re | 2007 |
Brain metabolic alterations in adolescents and young adults with fetal alcohol spectrum disorders.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Case-Control Studies; Central Nervous System Depressants; C | 2006 |
Glutamate transporter GLAST/EAAT1 directs cell surface expression of FXYD2/gamma subunit of Na, K-ATPase in human fetal astrocytes.
Topics: Abortion, Induced; Aspartic Acid; Astrocytes; Biological Transport; Biotinylation; Cell Membrane; Ce | 2007 |
An activating mutation in the PDGF receptor-beta causes abnormal morphology in the mouse placenta.
Topics: Animals; Aspartic Acid; Cell Proliferation; Cell Shape; Cells, Cultured; Embryo Loss; Embryonic Stem | 2007 |
Preferential vulnerability of mesencephalic dopamine neurons to glutamate transporter dysfunction.
Topics: alpha-Synuclein; Analysis of Variance; Animals; Aspartic Acid; Cells, Cultured; Dicarboxylic Acids; | 2008 |
Protective effect of noninherited maternal HLA-DR antigens on rheumatoid arthritis development.
Topics: Alanine; Alleles; Arginine; Arthritis, Rheumatoid; Aspartic Acid; Child; Cohort Studies; Epitopes; F | 2007 |
Acute and repeated dose oral toxicity of N-acetyl-l-aspartic acid in Sprague-Dawley rats.
Topics: Administration, Oral; Animals; Aspartic Acid; Behavior, Animal; Blood Cell Count; Blood Chemical Ana | 2008 |
Metabolic assessment of the brain using proton magnetic resonance spectroscopy in a growth-restricted human fetus: case report.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Child, Preschool; Choline; Female; Fetal Growth Retard | 2008 |
Free amino acids of human foetal and adult liver.
Topics: Adult; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Cystine; Female; Fetus; Glutamates; Glycin | 1966 |
Effect of pregnancy and hormones on the activity of aspartate transcarbamylase and the level of nucleic acids in the mammary gland of the rat.
Topics: Animals; Aspartic Acid; Body Weight; Carbon Isotopes; Colorimetry; DNA; Enzymes; Estradiol; Female; | 1967 |
Postnatal changes in brain N-acetyl-L-aspartic acid content of normal and hypothyroid suckling rats.
Topics: Animal Feed; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Chemistry; Chromatography, Gas; | 1967 |
Biochemical development of the human brain. III. Benzodiazepine receptors, free gamma-aminobutyrate (GABA) and other amino acids.
Topics: Adult; Aged; Aging; Amino Acids; Aspartic Acid; Brain; Cerebellum; Female; Flunitrazepam; Frontal Lo | 1982 |
Hemoglobin A2 Fitzroy delta 142 Ala----Asp: a new delta-chain variant.
Topics: Adult; Alanine; Amino Acid Sequence; Amino Acids; Aspartic Acid; Blood Protein Electrophoresis; Chro | 1984 |
[Effects of maltose infusion on amino acid composition of maternal venous blood and fetal blood in utero].
Topics: Adult; Amino Acids; Aspartic Acid; Blood Glucose; Female; Fetal Blood; Humans; Infusions, Parenteral | 1983 |
Kinetic properties of placental aminopeptidase A: N-terminal degradation of angiotensin II.
Topics: Amino Acids; Aminopeptidases; Angiotensin II; Anti-Bacterial Agents; Aspartic Acid; Cations, Divalen | 1983 |
Neonatal aspartate treatment: effects on arcuate nucleus morphology, organ weights, and reproductive function.
Topics: Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus; Aspartic Acid; Female; Fertility; Male; | 1984 |
Embryotoxicity in mice of phosphonacetyl-L-aspartic acid (PALA), a new antitumor agent. I. Embryolethal, teratogenic, and cytogenetic effects.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Aspartic Acid; Chromosomes, Human; Dose | 1980 |
Renal gluconeogenesis in pregnant and non-pregnant sheep.
Topics: Alanine; Animals; Aspartic Acid; Female; Gluconeogenesis; Glutamates; Glutamine; Glycerol; Glycine; | 1980 |
[New placental protein (PP15) with immunosuppressive properties (author's transl)].
Topics: Aspartic Acid; Female; Glutamates; Humans; Immunosuppressive Agents; Isoleucine; Leucine; Lymphocyte | 1980 |
Substitutions of aspartic acid for glycine-220 and of arginine for glycine-664 in the triple helix of the pro alpha 1(I) chain of type I procollagen produce lethal osteogenesis imperfecta and disrupt the ability of collagen fibrils to incorporate crystall
Topics: Adult; Arginine; Aspartic Acid; Bone and Bones; Calcification, Physiologic; Collagen; Cyanogen Bromi | 1995 |
Alteration of the morphology and neurochemistry of the developing mammalian nervous system by hydrogen sulphide.
Topics: Animals; Aspartic Acid; Brain; Cerebellum; Chromatography, High Pressure Liquid; Embryonic and Fetal | 1995 |
Prenatal detection of Canavan disease (aspartoacylase deficiency) by DNA analysis.
Topics: Amidohydrolases; Amniotic Fluid; Aspartic Acid; Base Sequence; Canavan Disease; DNA; Female; Humans; | 1994 |
Differences in amino acid content of preimplantation mouse embryos that develop in vitro versus in vivo: in vitro effects of five amino acids that are abundant in oviductal secretions.
Topics: Amino Acids; Animals; Aspartic Acid; Blastocyst; Culture Media; Embryonic and Fetal Development; Fal | 1995 |
Partial purification and kinetic properties of human placental cytosolic aspartate transaminase.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Bacteria; Cytosol; Dietary Proteins; Female; Hu | 1995 |
Substitution of aspartic acid for glycine at position 310 in type II collagen produces achondrogenesis II, and substitution of serine at position 805 produces hypochondrogenesis: analysis of genotype-phenotype relationships.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Bone Diseases, Developmental; Cartilage; Cells, C | 1995 |
Potentiation of magnesium-deficiency-induced foetotoxicity by concomitant iron deficiency and its prevention by adequate supply via drinking water.
Topics: Administration, Oral; Anemia, Hypochromic; Animals; Aspartic Acid; Biological Availability; Birth We | 1994 |
Detection of D-aspartate in tau proteins associated with Alzheimer paired helical filaments.
Topics: Alzheimer Disease; Amino Acids; Aspartic Acid; Brain Chemistry; Electrophoresis, Polyacrylamide Gel; | 1995 |
(2S,3S,4R)-2-(carboxycyclopropyl)glycine, a potent and competitive inhibitor of both glial and neuronal uptake of glutamate.
Topics: Amino Acids, Dicarboxylic; Animals; Anti-Bacterial Agents; Asparagine; Aspartic Acid; Astrocytes; Ce | 1993 |
Long-term effects of perinatal asphyxia on basal ganglia neurotransmitter systems studied with microdialysis in rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Cesarean | 1994 |
"In vivo" glutamic acid metabolism in late pregnant rats.
Topics: Animals; Aspartic Acid; Blood Glucose; Blood Proteins; Female; Gluconeogenesis; Glucose; Glutamates; | 1993 |
Substitution of an aspartic acid for glycine 700 in the alpha 2(I) chain of type I collagen in a recurrent lethal type II osteogenesis imperfecta dramatically affects the mineralization of bone.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Bone and Bones; Calcification, Physiologic; Cells | 1994 |
Aspartate-aminopeptidase activity during the estrous cycle and the pregnancy in rat brain and pituitary gland.
Topics: Aminopeptidases; Animals; Aspartic Acid; Brain; Estrus; Female; Glutamyl Aminopeptidase; Pituitary G | 1993 |
Probing the active site of human aldose reductase. Site-directed mutagenesis of Asp-43, Tyr-48, Lys-77, and His-110.
Topics: Aldehyde Reductase; Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; DNA Primers; F | 1993 |
Specific amino acids modulate the embryotoxicity of nickel chloride and its transfer to the rat embryo in vitro.
Topics: Amino Acids; Animals; Aspartic Acid; Biological Transport; Cysteine; Embryo, Mammalian; Embryonic an | 1993 |
Reliable prenatal diagnosis of Canavan disease (aspartoacylase deficiency): comparison of enzymatic and metabolite analysis.
Topics: Amniotic Fluid; Aspartic Acid; Canavan Disease; Female; Fetal Diseases; Humans; Pregnancy; Prenatal | 1993 |
Prenatal detection of Canavan disease by measurement of N-acetyl-L-aspartate in amniotic fluid.
Topics: Adult; Amniotic Fluid; Aspartic Acid; Canavan Disease; Female; Humans; Pregnancy; Prenatal Diagnosis | 1993 |
Identification of an active acidic residue in the catalytic site of beta-hexosaminidase.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Bacteria; Base Sequence; beta-N-Acetylhexosaminidases; | 1996 |
Accumulation of cytotoxins during the development of seizures and edema after hypoxic-ischemic injury in late gestation fetal sheep.
Topics: Animals; Aspartic Acid; Brain Edema; Brain Ischemia; Cytotoxins; Electroencephalography; Extracellul | 1996 |
Profile of monoamine and excitatory amino acid release in rat supraoptic nucleus over parturition.
Topics: Animals; Aspartic Acid; Biogenic Monoamines; Dopamine; Excitatory Amino Acids; Female; Glutamic Acid | 1997 |
Pharmacological characterisation of voltage-sensitive calcium channels and neurotransmitter release from mouse cerebellar granule cells in culture.
Topics: Animals; Aspartic Acid; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cerebellum; Dos | 1997 |
Neuronal maturation and N-acetyl-L-aspartic acid development in human fetal and child brains.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Chemistry; Cellular Senescence; Cerebral Cortex; Chil | 1997 |
Increased cerebrospinal fluid concentration of aspartate but decreased concentration of nitric oxide breakdown products in women experiencing visceral pain during active labour.
Topics: Adult; Aged; Analgesia; Aspartic Acid; Cesarean Section; Delivery, Obstetric; Enkephalin, Methionine | 1997 |
Ontogeny of neurotransmitter amino acids in human fetal brains.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Amino Acids; Aspartic Acid; Brain; Female; g | 1997 |
Effect of perinatal asphyxia on systemic and intracerebral pH and glycolysis metabolism in the rat.
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain Chemistry; Brain Diseases; Corpus Striatum; Female; | 1997 |
MR imaging, MR angiography, and MR spectroscopy of the brain in eclampsia.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Edema; Brain Ischemia; Cerebral Arteries; Choline; Cr | 1997 |
Neurovirulence in feline immunodeficiency virus-infected neonatal cats is viral strain specific and dependent on systemic immune suppression.
Topics: Animals; Animals, Newborn; Aspartic Acid; Base Sequence; Brain; Cats; Cell Death; DNA Primers; DNA, | 1998 |
Prenatal ethanol exposure diminishes activity-dependent potentiation of amino acid neurotransmitter release in adult rat offspring.
Topics: Age Factors; Animals; Aspartic Acid; Culture Techniques; Ethanol; Female; Fetal Alcohol Spectrum Dis | 1998 |
Amniotic fluid amino and nucleic acid in normal and neural tube defect pregnancies. A comparison.
Topics: Amino Acids; Amniotic Fluid; Analysis of Variance; Aspartic Acid; Case-Control Studies; Female; Feta | 1999 |
Metabolite changes in neonatal rat brain during and after cerebral hypoxia-ischemia: a magnetic resonance spectroscopic imaging study.
Topics: Aging; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Ischemia; Cerebral Infarction; Female; | 1999 |
Histological changes and neurotransmitter levels three months following perinatal asphyxia in the rat.
Topics: Animals; Animals, Newborn; Arginine; Aspartic Acid; Asphyxia; Brain; Cell Count; Cerebellum; Corpus | 1999 |
Prenatal diagnosis of Canavan disease--problems and dilemmas.
Topics: Amidohydrolases; Amniotic Fluid; Aspartic Acid; Canavan Disease; Female; Fetal Diseases; Humans; Inf | 1999 |
The regulation of Na(+)-dependent anionic amino acid transport by the rat mammary gland.
Topics: Animals; Aspartic Acid; Biological Transport; Bromocriptine; Carrier Proteins; Female; Glutamic Acid | 1999 |
Perinatal complications and abnormal proton metabolite concentrations in frontal cortex of adolescents seen on magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain Damage, Chronic; Choline; Creatine; Female; Follow-Up Studies; Frontal Lobe; Hu | 2000 |
Intestinal apical amino acid absorption during development of the pig.
Topics: Age Factors; Amino Acids; Animals; Animals, Suckling; Aspartic Acid; Female; Intestinal Absorption; | 2001 |
Brain proton magnetic resonance spectroscopy and imaging in children exposed to cocaine in utero.
Topics: Aspartic Acid; Brain; Case-Control Studies; Child; Cocaine; Creatinine; Female; Humans; Magnetic Res | 2001 |
2-NAP, a peripheral CCK-A receptor antagonist, modulates the development of a preference for the mother by the newborn lamb.
Topics: Animals; Animals, Newborn; Aspartic Acid; Behavior, Animal; Devazepide; Female; Hormone Antagonists; | 2000 |
Human oestrogenic 17beta-hydroxysteroid dehydrogenase specificity: enzyme regulation through an NADPH-dependent substrate inhibition towards the highly specific oestrone reduction.
Topics: 17-Hydroxysteroid Dehydrogenases; Aspartic Acid; Blood Proteins; Dehydroepiandrosterone; Dihydrotest | 2001 |
The missense Glu298Asp variant of the endothelial nitric oxide synthase gene is strongly associated with placental abruption.
Topics: Abruptio Placentae; Adult; Aspartic Acid; DNA; Female; Gene Frequency; Genetic Testing; Genotype; Gl | 2001 |
Prenatal exposure to methyl mercury in rats: focus on changes in kynurenine pathway.
Topics: Animals; Aspartic Acid; Female; Fetus; Glutamic Acid; Hippocampus; Kynurenine; Mercury Poisoning, Ne | 2001 |
Three-dimensional proton MR spectroscopic imaging of premature and term neonates.
Topics: Aspartic Acid; Brain; Brain Mapping; Cerebral Hemorrhage; Choline; Chorioamnionitis; Creatine; Energ | 2001 |
Regulation of glutamate transport and transport proteins in a placental cell line.
Topics: Amino Acid Transport System X-AG; Amino Acids; Animals; Aspartic Acid; ATP-Binding Cassette Transpor | 2001 |
Physiological importance of system A-mediated amino acid transport to rat fetal development.
Topics: Amino Acid Transport System A; Amino Acid Transport System X-AG; Animals; Aspartic Acid; beta-Alanin | 2002 |
Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome.
Topics: Adult; Aspartic Acid; Brain Diseases; Choline; Confusion; Creatine; Female; Headache; Humans; Magnet | 2002 |
Some effects of glucose concentration and anoxia on glycolysis and metabolite concentrations in the perfused liver of fetal guinea pig.
Topics: Adenine Nucleotides; Animals; Aspartic Acid; Citric Acid Cycle; Female; Fructosediphosphates; Gestat | 1978 |
[Effect of environment of the electric power plant Turów on the female body].
Topics: Alanine; Alanine Transaminase; Aspartate Aminotransferases; Aspartic Acid; Cystinyl Aminopeptidase; | 1979 |
Placental transfer of aspartate and its metabolites in the primate.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Erythrocytes; Female; Fetus; Haplorhini; I | 1979 |
Ontogeny of gluconeogenesis in the bovine fetus: influence of maternal dietary energy.
Topics: Alanine; Animal Nutritional Physiological Phenomena; Animals; Aspartate Aminotransferases; Aspartic | 1977 |
Transfer of glutamic acid across the human placenta perfused in vitro.
Topics: Alanine; Aspartic Acid; Female; Glutamates; Glutamine; Glycine; Humans; In Vitro Techniques; Leucine | 1979 |
Structure of the carbohydrate chain of free secretory component from human milk.
Topics: Amino Acids; Asparagine; Aspartic Acid; Carbohydrates; Female; Glycopeptides; Humans; Immunoglobulin | 1979 |
Hemoglobin Sunshine Seth - alpha 2 (94 (G1) Asp replaced by His) beta 2.
Topics: Amino Acids; Aspartic Acid; Child, Preschool; Female; Fetal Blood; Globins; Hematologic Tests; Hemog | 1979 |
Plasma, erythrocyte and human milk levels of free amino acids in lactating women administered aspartame or lactose.
Topics: Adult; Amino Acids; Aspartame; Aspartic Acid; Breast Feeding; Dipeptides; Erythrocytes; Female; Huma | 1979 |
[Activity of various enzymes in the blood of pregnant women and their fetuses with low body weight].
Topics: Alanine; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Aspartic Acid; Cre | 1979 |
Uterine uptake of amino acids and placental glutamine--glutamate balance in the pregnant ewe.
Topics: Amino Acids; Animals; Aspartic Acid; Female; Glutamates; Glutamine; Maternal-Fetal Exchange; Oxygen | 1979 |
[Study of the influence of arginine aspartate in agalactia and hypogalactia].
Topics: Adolescent; Adrenal Glands; Adult; Arginine; Aspartic Acid; Female; Humans; Lactation Disorders; Pit | 1977 |
The effect of L-aspartic acid, L-alanine, and hemoglobin on trypan blue-induced embryolethality and gross fetal malformations in gestating albino mice.
Topics: Abnormalities, Drug-Induced; Alanine; Animals; Aspartic Acid; Body Weight; Drug Interactions; Female | 1977 |
[Changes in the free amino acid content of rat brain during formation and fixation of defensive conditioned reflexes].
Topics: Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Conditioning, Classical; Ergotism; Female; Fet | 1978 |
Ammonia overloading in hepatocytes isolated from liver of fetal and adult rats.
Topics: Alanine; Aminooxyacetic Acid; Ammonia; Animals; Aspartic Acid; Female; Fructose; Glucose; Glutamates | 1979 |
[Teratogenic effect of N-phthaloyl-L-aspartic acid on the mouse (author's transl)].
Topics: Animals; Aspartic Acid; Female; Mice; Mice, Inbred Strains; Phthalimides; Pregnancy; Stereoisomerism | 1977 |
Changes in free amino acids and peptides in the haemolymph of Glossina austeni during the reproductive cycle.
Topics: Amino Acids; Animals; Aspartic Acid; Female; Hemolymph; Hydrolysis; Lysine; Peptides; Phenylalanine; | 1978 |
Brain damage and oral intake of certain amino acids.
Topics: Administration, Oral; Age Factors; Animals; Aspartic Acid; Brain Damage, Chronic; Breast; Cysteine; | 1976 |
Amino acid nutrition of the fetal lamb.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Female; Fetal Blood | 1977 |
[Nepsilon-(beta-Aspartyl)lysine and Nepsilon-(gamma-glutamyl)lysine crosslinkings in bovine colostrum (author's transl)].
Topics: Animals; Aspartic Acid; Cattle; Colostrum; Female; Glutamine; Lysine; Oligopeptides; Pregnancy | 1976 |
Umbilical uptake of amino acids in the unstressed fetal lamb.
Topics: Amino Acids; Animals; Aspartic Acid; Carbon; Female; Fetal Blood; Glutamates; Maternal-Fetal Exchang | 1976 |
Letter: Hazards in indiscriminate use of sweeteners containing phenylalanine.
Topics: Aspartic Acid; Diet; Dipeptides; Female; Fetus; Heterozygote; Homozygote; Humans; Phenylalanine; Phe | 1975 |
Letter: Safety of aspartame as a sweetener.
Topics: Aspartic Acid; Dipeptides; Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Sweetening Ag | 1975 |
Preparation of mouse embryos for the evaluation of hormone effects.
Topics: Amino Acids; Animals; Aspartic Acid; Culture Media; Estradiol; Female; Glutamates; Lysine; Mice; Pre | 1975 |
Synthetic sweetners: cyclamates, saccharin, aspartame.
Topics: Animals; Aspartame; Aspartic Acid; Beverages; Cyclamates; Cyclohexylamines; Diet, Reducing; Dipeptid | 1975 |
Age-related changes in binding to excitatory amino acid uptake sites in human cerebellum.
Topics: Aged; Aging; Amino Acids; Aspartic Acid; Autoradiography; Cerebellar Cortex; Cerebellum; Child, Pres | 1992 |
Prenatal diagnosis of Canavan disease.
Topics: Amidohydrolases; Amnion; Amniotic Fluid; Aspartic Acid; Cells, Cultured; Chorionic Villi; Female; Hu | 1992 |
Prenatal diagnosis of Canavan disease.
Topics: Aspartic Acid; Central Nervous System Diseases; Female; Fetal Diseases; Humans; Pregnancy; Prenatal | 1992 |
Oxytocin, amino acid and monoamine release in the region of the medial preoptic area and bed nucleus of the stria terminalis of the sheep during parturition and suckling.
Topics: Amino Acids; Animals; Aspartic Acid; Dopamine; Estradiol; Female; gamma-Aminobutyric Acid; Infusions | 1992 |
Prenatal detection of Canavan disease.
Topics: Amniotic Fluid; Aspartic Acid; Female; Fetal Diseases; Humans; Infant, Newborn; Male; Methods; Nervo | 1991 |
Parallel expression of synaptophysin and evoked neurotransmitter release during development of cultured neurons.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cerebral Cortex; Female; gamma-Aminobutyric Aci | 1991 |
Polyamines potentiate NMDA induced whole-cell currents in cultured striatal neurons.
Topics: Animals; Aspartic Acid; Cells, Cultured; Corpus Striatum; Female; Fetus; Ion Channels; N-Methylaspar | 1990 |
Stable isotope dilution analysis of N-acetylaspartic acid in CSF, blood, urine and amniotic fluid: accurate postnatal diagnosis and the potential for prenatal diagnosis of Canavan disease.
Topics: Amidohydrolases; Amniotic Fluid; Aspartic Acid; Body Fluids; Female; Humans; Indicator Dilution Tech | 1991 |
Effects of hypoxia on release of amino acid neurotransmitters from fetal lamb brain in vitro.
Topics: Amino Acids; Animals; Aspartic Acid; Culture Techniques; Female; Glutamates; Glutamic Acid; Glycine; | 1990 |
Selectivity of the cleavage/attachment site of phosphatidylinositol-glycan-anchored membrane proteins determined by site-specific mutagenesis at Asp-484 of placental alkaline phosphatase.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Animals; Aspartic Acid; Bromelains; Cell Line; Ethanolami | 1990 |
Role of the paraventricular nucleus in controlling the frequency of milk ejection and the facilitatory effect of centrally administered oxytocin in the suckled rat.
Topics: Animals; Aspartic Acid; Female; Injections, Intraventricular; Lactation; Milk Ejection; N-Methylaspa | 1990 |
GABA does not protect cerebro-cortical cultures against excitotoxic cell death.
Topics: Animals; Aspartic Acid; Cell Survival; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Glutamates; | 1990 |
[Magnesium and potassium aspartate during the third pregnancy trimester].
Topics: Adult; Aspartic Acid; Female; Humans; Infant, Newborn; Obstetric Labor, Premature; Parity; Pregnancy | 1990 |
Assay of aspartylglycosylaminase by high-performance liquid chromatography.
Topics: Acetylglucosamine; Amniotic Fluid; Aspartic Acid; Aspartylglucosylaminase; Brain; Carbocysteine; Cho | 1990 |
Hb F-Forest Park, a new A gamma variant with two amino acid substitutions, 75(E19)Ile----Thr and 73(E17)Asp----Asn, which can be identified in adults by gene-mapping analysis.
Topics: Asparagine; Aspartic Acid; Base Sequence; DNA; DNA Restriction Enzymes; Female; Fetal Blood; Fetal H | 1985 |
Hb F-Urumqi G gamma I22(B4)Asp----Gly: a new fetal hemoglobin variant found in a Uygur baby.
Topics: Amino Acid Sequence; Aspartic Acid; China; Female; Fetal Blood; Fetal Hemoglobin; Genetic Variation; | 1986 |
Cycloleucine blocks NMDA responses in cultured hippocampal neurones under voltage clamp: antagonism at the strychnine-insensitive glycine receptor.
Topics: Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cycloleucine; Electrophysiology; Female; Hippo | 1989 |
A potent antagonist of the strychnine insensitive glycine receptor has anticonvulsant properties.
Topics: Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Cortical Spreading Depression; Female; gam | 1989 |
Anionic amino acid uptake by microvillous membrane vesicles from human placenta.
Topics: Amino Acids; Anions; Aspartic Acid; Electrochemistry; Female; Glutamates; Glutamic Acid; Humans; Hyd | 1989 |
Qualitative changes in luteinizing hormone and prolactin responses to N-methyl-aspartic acid during lactation in the rat.
Topics: Animals; Aspartic Acid; Female; Hypothalamus; Lactation; Luteinizing Hormone; Male; N-Methylaspartat | 1989 |
Aspartame. Review of safety issues. Council on Scientific Affairs.
Topics: Adolescent; Adult; Animals; Aspartame; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplas | 1985 |
Synaptic transmission between dorsal root ganglion and dorsal horn neurons in culture: antagonism of monosynaptic excitatory postsynaptic potentials and glutamate excitation by kynurenate.
Topics: Animals; Aspartic Acid; Cells, Cultured; Evoked Potentials; Female; Ganglia, Spinal; Glutamates; Glu | 1985 |
Maternal undernutrition during lactation: effect on amino acids in brain regions of offspring.
Topics: Amino Acids; Animals; Aspartic Acid; Body Weight; Brain Chemistry; Corpus Striatum; Female; gamma-Am | 1985 |
Changes in the state of the excitatory synaptic system in the hippocampus on prolonged exposure to excitatory amino acids and antagonists.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Animals; Aspartic Acid; Dipeptid | 1988 |
[Evaluation of the efficacy of the intravenous admixture of aspartate magnesium hydrochloride with beta-mimetics in the treatment of impending premature labor].
Topics: Adrenergic beta-Agonists; Aspartic Acid; Drug Combinations; Female; Humans; Infusions, Intravenous; | 1988 |
High concentrations of naloxone attenuate N-methyl-D-aspartate receptor-mediated neurotoxicity.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Female; L-Lactate Dehydrogenase; Mice; N-M | 1987 |
The effects of fetal energy depletion on amniotic fluid concentrations of amino acids, organic acids and related metabolites.
Topics: Adenosine Triphosphate; Amino Acids; Amniotic Fluid; Arginine; Aspartic Acid; Asphyxia Neonatorum; D | 1988 |
Saccharin and aspartame. Are they safe to consume during pregnancy?
Topics: Aspartame; Aspartic Acid; Dipeptides; Female; Humans; Methanol; Phenylalanine; Pregnancy; Saccharin | 1988 |
[Usefulness of the addition of aspartate magnesium hydrochloride via intravenous route to beta mimetics in the treatment of threatened premature labor].
Topics: Adult; Aspartic Acid; Drug Evaluation; Drug Therapy, Combination; Female; Hexoprenaline; Humans; Mag | 1988 |
Neurotoxic lesions of the anterior hypothalamus disrupt the photoperiodic but not the circadian system of the Syrian hamster.
Topics: Animals; Aspartic Acid; Circadian Rhythm; Cricetinae; Estrus; Female; Hypothalamus, Anterior; Light; | 1985 |
Is intestinal transport of sugars and amino acids subject to critical-period programming?
Topics: Amino Acids; Animals; Aspartic Acid; Biological Transport; Body Weight; Carbohydrate Metabolism; Die | 1985 |
Effect of extracellular potassium on amino acid transport and membrane potential in fetal human fibroblasts.
Topics: Amino Acids; Aminoisobutyric Acids; Aspartic Acid; Biological Transport, Active; Body Water; Female; | 1986 |
Contragestational profile of the tumor-inhibiting agent, L-alanosine, in the rat and the hamster.
Topics: Adenine; Alanine; Animals; Antibiotics, Antineoplastic; Aspartic Acid; Cell Division; Cricetinae; Do | 1985 |
[Studies on L-glutamate transport mechanism in human placental trophoblast microvilli membrane vesicles].
Topics: Aspartic Acid; Biological Transport; Cells, Cultured; Female; Glutamates; Humans; Ions; Maternal-Fet | 1985 |
Prenatal karyotype analysis in high risk families.
Topics: Aminohydrolases; Amniocentesis; Amniotic Fluid; Aspartic Acid; Cells, Cultured; Chromosome Aberratio | 1973 |
Pseudoisozymes of hepatic tyrosine aminotransferase.
Topics: Age Factors; Amino Acids; Animals; Aspartate Aminotransferases; Aspartic Acid; Cells, Cultured; Cros | 1974 |
Regional changes in amino acid content in developing rat brain.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Brain; Cerebellum; Cerebral Cortex; Ch | 1974 |
Isolation of immunoglobulin A (IgA) from human colostrum.
Topics: Alkylation; Amino Acids; Aspartic Acid; Buffers; Chromatography, Gel; Colostrum; Cysteine; Electroph | 1966 |
The lethal effect of ethionine administered to guinea pigs.
Topics: Acetoacetates; Acidosis; Adenine Nucleotides; Adenosine Triphosphate; Animals; Aspartic Acid; Blood | 1967 |
Biochemical studies of the embryotoxic action of 6-aminonicotinamide.
Topics: Abnormalities, Drug-Induced; Acetates; Aspartic Acid; Carbon Isotopes; DNA; Embryo, Mammalian; Embry | 1970 |
Serum aminopeptidases, "angiotensinase," and hypertension. II. Amino acid beta-napthylamide hydrolysis by normal and hypertensive serum.
Topics: Aminopeptidases; Angiotensin II; Aspartic Acid; Colorimetry; Endopeptidases; Enzymes; Female; Humans | 1965 |
Progressive changes in the enzyme levels of mouse foetal liver.
Topics: Animals; Arginase; Aspartic Acid; Carbamates; Female; Fetus; Fructose; Fructose-Bisphosphatase; Fruc | 1971 |
The metabolic fate of the products of citrate cleavage. Adenosine triphosphate-citrate lyase and nicotinamide-adenine dinucleotide phosphate-linked malate dehydrogenase in foetal and adult liver from ruminants and non-ruminants.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Cattle; Citrates; F | 1968 |
Cytomorphometry of developing rat liver and its application to enzymic differentiation.
Topics: Aging; Animals; Aspartic Acid; Cell Count; Female; Glucagon; Glucokinase; Glucosyltransferases; Glyc | 1972 |
Hormonal regulation of rat mammary gland enzyme activities and metabolite patterns.
Topics: Adenine Nucleotides; Adrenal Glands; Adrenalectomy; Alcohol Oxidoreductases; Aldehyde-Lyases; Animal | 1972 |
Haemoglobin F auckland G gamma 7 Asp leads to Asn: further evidence for multiple genes for the gamma chain.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Chromatography, Ion Exchange; Female; F | 1974 |
Amino acid transport in human placental slices.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Biological Transport, | 1974 |
Human adenylosuccinate synthetase. Partial purification, kinetic and regulatory properties of the enzyme from placenta.
Topics: Aspartic Acid; Binding, Competitive; Carbon Radioisotopes; Cations, Divalent; Chromatography, DEAE-C | 1974 |
Amino acid and glucose uptake by the isolated perfused guinea-pig mammary gland.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Radioisotopes; Caseins; Female; Glucose; Glutam | 1974 |
[Interactions of phytoagglutinins with urinary glycopeptides. Analysis of a glycopeptide inhibitor of phytoagglutinin from Robinia pseudo acacia].
Topics: Amino Acids; Aspartic Acid; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion | 1972 |
Effects of mother-litter separation on survival, growth, and brain amino acid levels.
Topics: Alanine; Amino Acids; Aminobutyrates; Animal Nutritional Physiological Phenomena; Animals; Animals, | 1972 |
Altered populations of acidic chromatin proteins in breast cancer cells.
Topics: Adenocarcinoma; Amino Acids; Animals; Aspartic Acid; Chromatin; Electrophoresis, Polyacrylamide Gel; | 1973 |
Haemoglobin J Nyanza: 21 (B2) Ala-Asp.
Topics: Adult; Alanine; Amino Acid Sequence; Amino Acids; Aspartic Acid; Chromatography, Ion Exchange; Elect | 1973 |
A clinical study of the compound Astra 2045 in the treatment of bovine hypocalcaemia with special reference to dosage levels.
Topics: Animals; Arrhythmias, Cardiac; Aspartic Acid; Calcium; Cattle; Cattle Diseases; Evaluation Studies a | 1973 |
Carbohydrate metabolism in pregnancy. X. Metabolic disposition of alanine by the perfused liver of the fasting pregnant rat.
Topics: Alanine; Alanine Transaminase; Ammonia; Animals; Aspartic Acid; Carbon Isotopes; Chromatography; Fas | 1973 |
Structural identification of haemoglobin F Kuala Lumpur: alpha2 gamma2 22(B4)Asp leads to Gly; 136 Ala.
Topics: Agar; Amino Acid Sequence; Amino Acids; Aspartic Acid; Blood Protein Electrophoresis; Cellulose; Chr | 1973 |
A spectrophotometric method for qualitative and quantitative determination of sialic acid in glycoproteins and glycopeptides.
Topics: Aspartic Acid; Binding Sites; Evaluation Studies as Topic; Female; Fetal Proteins; Glycopeptides; Gl | 1973 |
Renal metabolism of amino acids and ammonia in fed and fasted pregnant sheep.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Animals; Arginine; Aspartic Acid; Catheterization; Citrulli | 1974 |
The metabolism of (14C) glucose by the brains of suckling rats intoxicated with inorganic lead.
Topics: Aging; Amino Acids; Animals; Aspartic Acid; Blood Glucose; Body Weight; Brain; Carbon Radioisotopes; | 1974 |
Changes with metabolic compartments in the brains of young rats ingesting lead.
Topics: Acetates; Aminobutyrates; Animals; Aspartic Acid; Blood Glucose; Brain; Carbon Radioisotopes; Female | 1974 |
Concentration gradients of amino acids between the uterine and blastocoelic fluid in the rabbit.
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Body Fluids; Female; Glutamates; | 1972 |
Effects of dietary vitamin B 6 on the utilization of monosodium glutamate by rats.
Topics: Aging; Alanine; Alanine Transaminase; Animals; Animals, Newborn; Aspartate Aminotransferases; Aspart | 1972 |
Monosodium glutamate: effect of plasma and breast milk amino acid levels in lactating women.
Topics: Alanine; Amino Acids; Aspartic Acid; Female; Food Additives; Glutamates; Glutamine; Humans; Lactatio | 1972 |
Endocrine control of free amino acids content in uterine fluid in pregnant rabbits.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Body Fluids; Castration; Corpus Luteum; Embry | 1972 |
Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancy. Preliminary report.
Topics: Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Arginine; Aspartic Acid; Citrulline; Cystine; | 1971 |
Uptake and incorporation of amino acids by cultured mouse embryos: estrogen stimulation.
Topics: Amino Acids; Animals; Aspartic Acid; Autoradiography; Carbon Isotopes; Culture Media; Culture Techni | 1971 |
The free amino acids of foetal brain in Tay-Sachs disease.
Topics: Amino Acids; Aminobutyrates; Aspartic Acid; Brain Chemistry; Female; Fetal Diseases; Glutamates; Glu | 1971 |
The development of urea cycle enzyme activity in the liver of foetal and neonatal rats.
Topics: Animals; Animals, Newborn; Arginase; Arginine; Aspartic Acid; Carbamates; Citrulline; Female; Fetus; | 1970 |
The development of gluconeogenesis in rat liver: experiments in vivo.
Topics: Animals; Animals, Newborn; Aspartic Acid; Carbon Isotopes; Female; Fetus; Gluconeogenesis; Lactates; | 1969 |
Nitrogenous compounds immobilized in an aged rat.
Topics: Age Factors; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography, Gas; Chromatography, Pap | 1970 |
Placental and fetal RNA metabolism. I. In vivo labeling of the fetal and placental RNA in the 14-day pregnant rat.
Topics: Animals; Aspartic Acid; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography; Female; F | 1970 |
The influence of pre-eclampsia and diabetes mellitus on plasma free amino acids in maternal, umbilical vein and infant blood.
Topics: Amino Acids; Aminobutyrates; Aspartic Acid; Birth Weight; Blood Proteins; Cesarean Section; Estriol; | 1971 |
Acetyl transport mechanisms. Metabolism of N-acetyl-L-aspartic acid in the non-nervous tissues of the rat.
Topics: Acetates; Animals; Aspartic Acid; Biological Transport; Carbon Dioxide; Carbon Isotopes; Female; Glu | 1968 |
Metabolite changes associated with initiation and maintenance of lactation in rats and cows.
Topics: Acids; Animals; Aspartic Acid; Carbohydrate Metabolism; Cattle; Female; Glucose; Glucosephosphate De | 1969 |
Free amino acids of normal and abnormal human placenta.
Topics: Amino Acids; Arginine; Asparagine; Aspartic Acid; Biological Transport, Active; Female; Glutamine; H | 1969 |
Changes with age in the utilization of glucose carbon in liver and brain.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Brain; Carbon; Carbon Isotopes; Centri | 1966 |