Page last updated: 2024-11-08

aspartic acid and Pheochromocytoma

aspartic acid has been researched along with Pheochromocytoma in 5 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

Research Excerpts

ExcerptRelevanceReference
"Mutations at aspartic acid 631 in Ret were reported in sporadic pheochromocytoma and medullary thyroid carcinoma."7.70Mechanism of Ret activation by a mutation at aspartic acid 631 identified in sporadic pheochromocytoma. ( Asai, N; Ichihara, M; Iwashita, T; Murakami, H; Ohmori, K; Takahashi, M; Takanari, H, 1999)
"Mutations at aspartic acid 631 in Ret were reported in sporadic pheochromocytoma and medullary thyroid carcinoma."3.70Mechanism of Ret activation by a mutation at aspartic acid 631 identified in sporadic pheochromocytoma. ( Asai, N; Ichihara, M; Iwashita, T; Murakami, H; Ohmori, K; Takahashi, M; Takanari, H, 1999)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Long, Z2
Sekine, M2
Adachi, M2
Furuchi, T2
Imai, K2
Nimura, N2
Homma, H2
Koyama, H1
Shimamoto, K1
Nakajima, T1
Zheng, S1
Ramachandran, B1
Haigh, JR1
Palos, TP1
Steger, K1
Howard, BD1
Asai, N1
Iwashita, T1
Murakami, H1
Takanari, H1
Ohmori, K1
Ichihara, M1
Takahashi, M1
Nakatsuka, S1
Hayashi, M1
Muroyama, A1
Otsuka, M1
Kozaki, S1
Yamada, H1
Moriyama, Y1

Other Studies

5 other studies available for aspartic acid and Pheochromocytoma

ArticleYear
Cell density inversely regulates D- and L-aspartate levels in rat pheochromocytoma MPT1 cells.
    Archives of biochemistry and biophysics, 2002, Aug-01, Volume: 404, Issue:1

    Topics: Animals; Aspartic Acid; Cell Count; Homeostasis; PC12 Cells; Pheochromocytoma; Rats; Stereoisomerism

2002
L-Glutamate in the extracellular space regulates endogenous D-aspartate homeostasis in rat pheochromocytoma MPT1 cells.
    Archives of biochemistry and biophysics, 2004, Apr-01, Volume: 424, Issue:1

    Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Cell Line, Tumor; Cysteine; Extracellular

2004
The induction of ret by Wnt-1 in PC12 cells is atypically dependent on continual Wnt-1 expression.
    Oncogene, 1996, Feb-01, Volume: 12, Issue:3

    Topics: Adrenal Gland Neoplasms; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Casse

1996
Mechanism of Ret activation by a mutation at aspartic acid 631 identified in sporadic pheochromocytoma.
    Biochemical and biophysical research communications, 1999, Feb-24, Volume: 255, Issue:3

    Topics: 3T3 Cells; Animals; Aspartic Acid; DNA Mutational Analysis; DNA, Neoplasm; Drosophila Proteins; Gene

1999
D-Aspartate is stored in secretory granules and released through a Ca(2+)-dependent pathway in a subset of rat pheochromocytoma PC12 cells.
    The Journal of biological chemistry, 2001, Jul-13, Volume: 276, Issue:28

    Topics: Adrenal Gland Neoplasms; Animals; Aspartic Acid; Biological Transport; Calcium; Exocytosis; PC12 Cel

2001