aspartic acid has been researched along with Parkinson Disease, Secondary in 14 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Parkinson Disease, Secondary: Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Manganese (Mn) is a well established neurotoxin associated with specific damage to the basal ganglia in humans." | 1.38 | Pathophysiology of manganese-associated neurotoxicity. ( Aschner, M; Criswell, SR; Dydak, U; Guilarte, TR; Racette, BA; Zheng, W, 2012) |
| "Carbon monoxide (CO) exposure is a common cause of toxic brain damage, whereby effects range from transient neurological dysfunction to coma and death." | 1.33 | Carbon monoxide brain toxicity: clinical, magnetic resonance imaging, magnetic resonance spectroscopy, and neuropsychological effects in 9 people. ( Prockop, LD, 2005) |
| "24 h after injection, rigidity and catalepsy were measured, as well as, at the end of the three week period, locomotion, rearing and exploratory behavior." | 1.31 | Local application of L- threo-hydroxyaspartate and malonate in rats in vivo induces rigidity and damages neurons of the substantia nigra, pars compacta. ( Loopuijt, LD, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lesage, S | 1 |
| Anheim, M | 1 |
| Letournel, F | 1 |
| Bousset, L | 1 |
| Honoré, A | 1 |
| Rozas, N | 1 |
| Pieri, L | 1 |
| Madiona, K | 1 |
| Dürr, A | 1 |
| Melki, R | 1 |
| Verny, C | 1 |
| Brice, A | 1 |
| Hou, Z | 1 |
| Zhang, Z | 1 |
| Meng, H | 1 |
| Lin, X | 1 |
| Sun, B | 1 |
| Lei, H | 1 |
| Fang, K | 1 |
| Fang, F | 1 |
| Liu, M | 1 |
| Liu, S | 1 |
| Bustos, G | 1 |
| Abarca, J | 1 |
| Bustos, V | 1 |
| Riquelme, E | 1 |
| Noriega, V | 1 |
| Moya, C | 1 |
| Campusano, J | 1 |
| Massie, A | 1 |
| Goursaud, S | 1 |
| Schallier, A | 1 |
| Vermoesen, K | 1 |
| Meshul, CK | 1 |
| Hermans, E | 1 |
| Michotte, Y | 1 |
| Wächter, T | 1 |
| Engeholm, M | 1 |
| Bisdas, S | 1 |
| Schittenhelm, J | 1 |
| Gasser, T | 1 |
| Krüger, R | 1 |
| Racette, BA | 1 |
| Aschner, M | 1 |
| Guilarte, TR | 1 |
| Dydak, U | 1 |
| Criswell, SR | 1 |
| Zheng, W | 1 |
| Loopuijt, LD | 1 |
| Yamasue, H | 1 |
| Fukui, T | 1 |
| Fukuda, R | 1 |
| Kasai, K | 1 |
| Iwanami, A | 1 |
| Kato, N | 1 |
| Kato, T | 1 |
| Prockop, LD | 1 |
| Rango, M | 1 |
| Canesi, M | 1 |
| Ghione, I | 1 |
| Farabola, M | 1 |
| Righini, A | 1 |
| Bresolin, N | 1 |
| Antonini, A | 1 |
| Pezzoli, G | 1 |
| Jenkins, BG | 1 |
| Brouillet, E | 1 |
| Chen, YC | 1 |
| Storey, E | 1 |
| Schulz, JB | 1 |
| Kirschner, P | 1 |
| Beal, MF | 1 |
| Rosen, BR | 1 |
| Federico, F | 1 |
| Simone, IL | 1 |
| Lucivero, V | 1 |
| Iliceto, G | 1 |
| De Mari, M | 1 |
| Giannini, P | 1 |
| Mezzapesa, DM | 1 |
| Tarantino, A | 1 |
| Lamberti, P | 1 |
| Kish, SJ | 1 |
| Chang, LJ | 1 |
| Mirchandani, L | 1 |
| Shannak, K | 1 |
| Hornykiewicz, O | 1 |
| Crossman, AR | 1 |
| Peggs, D | 1 |
| Boyce, S | 1 |
| Luquin, MR | 1 |
| Sambrook, MA | 1 |
14 other studies available for aspartic acid and Parkinson Disease, Secondary
| Article | Year |
|---|---|
G51D α-synuclein mutation causes a novel parkinsonian-pyramidal syndrome.
Topics: Adult; Aged; Aged, 80 and over; alpha-Synuclein; Amyloid; Aspartic Acid; Blepharospasm; Caspase 3; D | 2013 |
Parkinson's disease: in vivo metabolic changes in the frontal and parietal cortices in 6-OHDA treated rats during different periods.
Topics: Animals; Aspartic Acid; Choline; Corpus Striatum; Creatine; Disease Models, Animal; Frontal Lobe; Fu | 2014 |
NMDA receptors mediate an early up-regulation of brain-derived neurotrophic factor expression in substantia nigra in a rat model of presymptomatic Parkinson's disease.
Topics: Analysis of Variance; Animals; Aspartic Acid; Brain-Derived Neurotrophic Factor; Cell Count; Disease | 2009 |
Time-dependent changes in GLT-1 functioning in striatum of hemi-Parkinson rats.
Topics: Animals; Aspartic Acid; Blotting, Western; Chromatography, High Pressure Liquid; Corpus Striatum; Do | 2010 |
Slowly progressive Parkinson syndrome due to thalamic butterfly astrocytoma.
Topics: Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Brain Stem; Choline; Glial Fibrillary Acidic Prot | 2011 |
Pathophysiology of manganese-associated neurotoxicity.
Topics: Air Pollutants, Occupational; Animals; Aspartic Acid; Brain; Dopamine; gamma-Aminobutyric Acid; Huma | 2012 |
Local application of L- threo-hydroxyaspartate and malonate in rats in vivo induces rigidity and damages neurons of the substantia nigra, pars compacta.
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain Mapping; Catalepsy; Cell Count; Coloring Agents; Loc | 2002 |
Drug-induced parkinsonism in relation to choline-containing compounds measured by 1H-MR spectroscopy in putamen of chronically medicated patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Basal Ganglia Diseases; Choline; Chronic Disease; Creati | 2003 |
Carbon monoxide brain toxicity: clinical, magnetic resonance imaging, magnetic resonance spectroscopy, and neuropsychological effects in 9 people.
Topics: Acute Disease; Adolescent; Adult; Aspartic Acid; Basal Ganglia; Brain; Carbon Monoxide Poisoning; Ch | 2005 |
Parkinson's disease, chronic hydrocarbon exposure and striatal neuronal damage: a 1-H MRS study.
Topics: Aged; Aspartic Acid; Choline; Creatine; Humans; Hydrocarbons; Magnetic Resonance Imaging; Magnetic R | 2006 |
Non-invasive neurochemical analysis of focal excitotoxic lesions in models of neurodegenerative illness using spectroscopic imaging.
Topics: Aging; Animals; Aspartic Acid; Electron Transport Complex II; Energy Metabolism; Huntington Disease; | 1996 |
Proton magnetic resonance spectroscopy in Parkinson's disease and atypical parkinsonian disorders.
Topics: Aged; Antiparkinson Agents; Aspartic Acid; Atrophy; Cerebral Cortex; Choline; Corpus Striatum; Creat | 1997 |
Progressive supranuclear palsy: relationship between extrapyramidal disturbances, dementia, and brain neurotransmitter markers.
Topics: Aged; Aspartic Acid; Basal Ganglia Diseases; Brain; Bulbar Palsy, Progressive; Choline O-Acetyltrans | 1985 |
Effect of the NMDA antagonist MK-801 on MPTP-induced parkinsonism in the monkey.
Topics: Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Injections, Intramuscular; Levodo | 1989 |