aspartic acid has been researched along with Osteoarthritis in 8 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Osteoarthritis is the most common form of human arthritis." | 5.33 | An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis. ( Fukuda, A; Iida, A; Ikegawa, S; Kawakami, A; Kizawa, H; Kotani, A; Kou, I; Mabuchi, A; Miyamoto, Y; Nakamura, K; Nakamura, Y; Notoya, K; Sudo, A; Uchida, A; Yamamoto, S, 2005) |
| "An association between osteoarthritis (OA) and functional polymorphisms in the aspartic acid (d) repeat of the asporin (ASPN) gene was reported in Japanese and Han Chinese populations." | 3.74 | Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians. ( Aponte, J; Atif, U; Brady, S; Chiano, M; Doherty, M; Hochberg, M; Jordan, JM; Kraus, VB; Loeser, R; Moskowitz, RW; Philip, A; Renner, JB; Wilson, AG; Woldu, EM, 2008) |
| "Osteoarthritis is the most common form of human arthritis." | 1.33 | An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis. ( Fukuda, A; Iida, A; Ikegawa, S; Kawakami, A; Kizawa, H; Kotani, A; Kou, I; Mabuchi, A; Miyamoto, Y; Nakamura, K; Nakamura, Y; Notoya, K; Sudo, A; Uchida, A; Yamamoto, S, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, X | 1 |
| Jiang, L | 1 |
| Lu, Y | 1 |
| Wang, C | 1 |
| Zhou, S | 1 |
| Wang, H | 1 |
| Tian, T | 1 |
| Kizawa, H | 1 |
| Kou, I | 1 |
| Iida, A | 1 |
| Sudo, A | 1 |
| Miyamoto, Y | 1 |
| Fukuda, A | 1 |
| Mabuchi, A | 1 |
| Kotani, A | 1 |
| Kawakami, A | 1 |
| Yamamoto, S | 1 |
| Uchida, A | 1 |
| Nakamura, K | 1 |
| Notoya, K | 1 |
| Nakamura, Y | 1 |
| Ikegawa, S | 3 |
| Rodriguez-Lopez, J | 1 |
| Pombo-Suarez, M | 1 |
| Liz, M | 1 |
| Gomez-Reino, JJ | 1 |
| Gonzalez, A | 1 |
| Jean, YH | 1 |
| Wen, ZH | 1 |
| Chang, YC | 1 |
| Lee, HS | 1 |
| Hsieh, SP | 1 |
| Wu, CT | 1 |
| Yeh, CC | 1 |
| Wong, CS | 1 |
| Song, YQ | 1 |
| Cheung, KM | 1 |
| Ho, DW | 1 |
| Poon, SC | 1 |
| Chiba, K | 1 |
| Kawaguchi, Y | 1 |
| Hirose, Y | 1 |
| Alini, M | 1 |
| Grad, S | 1 |
| Yee, AF | 1 |
| Leong, JC | 1 |
| Luk, KD | 1 |
| Yip, SP | 1 |
| Karppinen, J | 1 |
| Cheah, KS | 1 |
| Sham, P | 1 |
| Chan, D | 1 |
| Atif, U | 1 |
| Philip, A | 1 |
| Aponte, J | 1 |
| Woldu, EM | 1 |
| Brady, S | 1 |
| Kraus, VB | 1 |
| Jordan, JM | 1 |
| Doherty, M | 1 |
| Wilson, AG | 1 |
| Moskowitz, RW | 1 |
| Hochberg, M | 1 |
| Loeser, R | 1 |
| Renner, JB | 1 |
| Chiano, M | 1 |
| Maroudas, A | 1 |
| Palla, G | 1 |
| Gilav, E | 1 |
2 reviews available for aspartic acid and Osteoarthritis
| Article | Year |
|---|---|
Association of aspartic acid repeat polymorphism in the asporin gene with osteoarthritis of knee, hip, and hand: A PRISMA-compliant meta-analysis.
Topics: Aspartic Acid; Extracellular Matrix Proteins; Humans; Osteoarthritis; Polymorphism, Genetic; Repetit | 2018 |
[Asporin, a susceptibility gene for osteoarthritis].
Topics: Alleles; Aspartic Acid; Extracellular Matrix Proteins; Genetic Predisposition to Disease; Humans; Os | 2006 |
6 other studies available for aspartic acid and Osteoarthritis
| Article | Year |
|---|---|
An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis.
Topics: Aggrecans; Aspartic Acid; Carrier Proteins; Chondrogenesis; Chromosome Mapping; Disease Susceptibili | 2005 |
Lack of association of a variable number of aspartic acid residues in the asporin gene with osteoarthritis susceptibility: case-control studies in Spanish Caucasians.
Topics: Arthroplasty, Replacement, Hip; Aspartic Acid; Base Sequence; Carrier Proteins; Case-Control Studies | 2006 |
Hyaluronic acid attenuates osteoarthritis development in the anterior cruciate ligament-transected knee: Association with excitatory amino acid release in the joint dialysate.
Topics: Animals; Anterior Cruciate Ligament Injuries; Aspartic Acid; Cartilage, Articular; Excitatory Amino | 2006 |
Association of the asporin D14 allele with lumbar-disc degeneration in Asians.
Topics: Adolescent; Adult; Alleles; Asian People; Aspartic Acid; Extracellular Matrix Proteins; Female; Gene | 2008 |
Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians.
Topics: Aged; Aspartic Acid; Extracellular Matrix Proteins; Female; Genetic Predisposition to Disease; Genot | 2008 |
Racemization of aspartic acid in human articular cartilage.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Cartilage, Articular; Femur Head; Humans; Osteoarthri | 1992 |