aspartic acid has been researched along with Osteoarthritis, Knee in 12 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Osteoarthritis, Knee: Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Osteoarthritis is the most common form of human arthritis." | 5.33 | An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis. ( Fukuda, A; Iida, A; Ikegawa, S; Kawakami, A; Kizawa, H; Kotani, A; Kou, I; Mabuchi, A; Miyamoto, Y; Nakamura, K; Nakamura, Y; Notoya, K; Sudo, A; Uchida, A; Yamamoto, S, 2005) |
| "Osteoarthritis is the most common form of human arthritis." | 1.33 | An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis. ( Fukuda, A; Iida, A; Ikegawa, S; Kawakami, A; Kizawa, H; Kotani, A; Kou, I; Mabuchi, A; Miyamoto, Y; Nakamura, K; Nakamura, Y; Notoya, K; Sudo, A; Uchida, A; Yamamoto, S, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Weerasekera, A | 1 |
| Morrissey, E | 1 |
| Kim, M | 1 |
| Saha, A | 1 |
| Lin, Y | 1 |
| Alshelh, Z | 1 |
| Torrado-Carvajal, A | 1 |
| Albrecht, D | 1 |
| Akeju, O | 1 |
| Kwon, YM | 1 |
| Bedair, H | 1 |
| Chen, AF | 1 |
| Napadow, V | 1 |
| Schreiber, K | 1 |
| Ratai, EM | 1 |
| Edwards, RR | 1 |
| Loggia, ML | 1 |
| Xing, D | 1 |
| Ma, XL | 1 |
| Ma, JX | 1 |
| Xu, WG | 1 |
| Wang, J | 1 |
| Yang, Y | 1 |
| Chen, Y | 1 |
| Ma, BY | 1 |
| Zhu, SW | 1 |
| Catterall, JB | 4 |
| Zura, RD | 2 |
| Bolognesi, MP | 1 |
| Kraus, VB | 4 |
| Taylor, AM | 1 |
| Hsueh, MF | 2 |
| Ranganath, LR | 1 |
| Gallagher, JA | 1 |
| Dillon, JP | 1 |
| Huebner, JL | 1 |
| Jean, YH | 1 |
| Wen, ZH | 1 |
| Chang, YC | 1 |
| Hsieh, SP | 1 |
| Lin, JD | 1 |
| Tang, CC | 1 |
| Chen, WF | 1 |
| Chou, AK | 1 |
| Wong, CS | 1 |
| Barr, D | 1 |
| Bolognesi, M | 2 |
| Stabler, TV | 1 |
| McCudden, CR | 1 |
| Zura, R | 1 |
| Jordan, JM | 1 |
| Renner, JB | 1 |
| Feng, S | 1 |
| Kizawa, H | 1 |
| Kou, I | 1 |
| Iida, A | 1 |
| Sudo, A | 1 |
| Miyamoto, Y | 1 |
| Fukuda, A | 1 |
| Mabuchi, A | 1 |
| Kotani, A | 1 |
| Kawakami, A | 1 |
| Yamamoto, S | 1 |
| Uchida, A | 1 |
| Nakamura, K | 1 |
| Notoya, K | 1 |
| Nakamura, Y | 1 |
| Ikegawa, S | 3 |
| Mustafa, Z | 1 |
| Dowling, B | 1 |
| Chapman, K | 1 |
| Sinsheimer, JS | 1 |
| Carr, A | 1 |
| Loughlin, J | 1 |
| Jiang, Q | 2 |
| Shi, D | 2 |
| Yi, L | 2 |
| Wang, Y | 2 |
| Nakamura, T | 2 |
| Qiao, D | 1 |
| Liu, C | 1 |
| Dai, J | 2 |
| Qin, J | 1 |
| Chen, D | 1 |
| Xu, Z | 1 |
| Song, JH | 1 |
| Lee, HS | 1 |
| Kim, CJ | 1 |
| Cho, YG | 1 |
| Park, YG | 1 |
| Nam, SW | 1 |
| Lee, JY | 1 |
| Park, WS | 1 |
1 review available for aspartic acid and Osteoarthritis, Knee
| Article | Year |
|---|---|
Association between aspartic acid repeat polymorphism of the asporin gene and susceptibility to knee osteoarthritis: a genetic meta-analysis.
Topics: Asian People; Aspartic Acid; Extracellular Matrix Proteins; Gene Frequency; Genetic Predisposition t | 2013 |
1 trial available for aspartic acid and Osteoarthritis, Knee
| Article | Year |
|---|---|
Protein modification by deamidation indicates variations in joint extracellular matrix turnover.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Arthroplasty, Replacement, Hip; Art | 2012 |
10 other studies available for aspartic acid and Osteoarthritis, Knee
| Article | Year |
|---|---|
Thalamic neurometabolite alterations in patients with knee osteoarthritis before and after total knee replacement.
Topics: Arthroplasty, Replacement, Knee; Aspartic Acid; Choline; Creatine; Humans; Magnetic Resonance Spectr | 2021 |
Aspartic acid racemization reveals a high turnover state in knee compared with hip osteoarthritic cartilage.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aspartic Acid; Cartilage, Articular; Case-C | 2016 |
Cartilage biomarkers in the osteoarthropathy of alkaptonuria reveal low turnover and accelerated ageing.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alkaptonuria; Aspartic Acid; Biomarkers; Cartilage Oligomeric | 2017 |
Increase in excitatory amino acid concentration and transporters expression in osteoarthritic knees of anterior cruciate ligament transected rabbits.
Topics: Animals; Anterior Cruciate Ligament; Aspartic Acid; Clinical Protocols; Excitatory Amino Acids; Glut | 2008 |
Post-translational aging of proteins in osteoarthritic cartilage and synovial fluid as measured by isomerized aspartate.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Cartilage, Articular; Glycosaminoglycans; Humans | 2009 |
An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis.
Topics: Aggrecans; Aspartic Acid; Carrier Proteins; Chondrogenesis; Chromosome Mapping; Disease Susceptibili | 2005 |
Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population.
Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement; Aspartic Acid; Carrier Proteins; Case-Control St | 2005 |
Replication of the association of the aspartic acid repeat polymorphism in the asporin gene with knee-osteoarthritis susceptibility in Han Chinese.
Topics: Adult; Aged; Aged, 80 and over; Asian People; Aspartic Acid; China; Extracellular Matrix Proteins; F | 2006 |
Association of the aspartic acid-repeat polymorphism in the asporin gene with age at onset of knee osteoarthritis in Han Chinese population.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Asian People; Aspartic Acid; China; Extracellular Matri | 2007 |
Aspartic acid repeat polymorphism of the asporin gene with susceptibility to osteoarthritis of the knee in a Korean population.
Topics: Asian People; Aspartic Acid; Case-Control Studies; Extracellular Matrix Proteins; Female; Gene Frequ | 2008 |