aspartic acid has been researched along with Obsessive-Compulsive Disorder in 38 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, N-acetyl-aspartate, a putative marker of neuronal viability, creatine/phosphocreatine, and choline levels were measured in the lateral and medical subregions of the left and right thalami using a multislice proton magnetic resonance spectroscopic imaging sequence in 11 treatment-naive, nondepressed obsessive-compulsive disorder outpatients, 8-15 years old, and 11 case-matched control subjects." | 3.70 | Proton spectroscopic imaging of the thalamus in treatment-naive pediatric obsessive-compulsive disorder. ( Fitzgerald, KD; Moore, GJ; Paulson, LA; Rosenberg, DR; Stewart, CM, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (5.26) | 18.2507 |
| 2000's | 17 (44.74) | 29.6817 |
| 2010's | 17 (44.74) | 24.3611 |
| 2020's | 2 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Kosová, E | 1 |
| Pajuelo, D | 1 |
| Fajnerová, I | 1 |
| Greguš, D | 1 |
| Brunovský, M | 1 |
| Stopková, P | 1 |
| Škoch, A | 1 |
| Fürstová, P | 1 |
| Španiel, F | 1 |
| Horáček, J | 1 |
| Biria, M | 1 |
| Cantonas, LM | 1 |
| Banca, P | 1 |
| Naaijen, J | 1 |
| Zwiers, MP | 1 |
| Forde, NJ | 1 |
| Williams, SC | 1 |
| Durston, S | 1 |
| Brandeis, D | 1 |
| Glennon, JC | 1 |
| Franke, B | 1 |
| Lythgoe, DJ | 1 |
| Buitelaar, JK | 1 |
| Moon, CM | 1 |
| Jeong, GW | 2 |
| Tükel, R | 2 |
| Aydın, K | 2 |
| Ertekin, E | 2 |
| Özyıldırım, SŞ | 2 |
| Taravari, V | 1 |
| Barburoğlu, M | 1 |
| Ortiz, AE | 1 |
| Ortiz, AG | 1 |
| Falcon, C | 2 |
| Morer, A | 2 |
| Plana, MT | 1 |
| Bargalló, N | 2 |
| Lázaro, L | 2 |
| Park, SE | 1 |
| Choi, NG | 1 |
| Ljungberg, M | 2 |
| Nilsson, MKL | 1 |
| Melin, K | 1 |
| Jönsson, L | 2 |
| Carlsson, A | 3 |
| Forssell-Aronsson, E | 2 |
| Ivarsson, T | 2 |
| Carlsson, M | 1 |
| Starck, G | 2 |
| Nilsson, M | 1 |
| Lundberg, S | 1 |
| Ribbelin, S | 1 |
| Ekholm, S | 1 |
| Carlsson, ML | 1 |
| Scherk, H | 2 |
| Backens, M | 2 |
| Zill, P | 1 |
| Schneider-Axmann, T | 2 |
| Wobrock, T | 1 |
| Usher, J | 2 |
| Reith, W | 2 |
| Falkai, P | 2 |
| Möller, HJ | 1 |
| Bondy, B | 1 |
| Gruber, O | 2 |
| Atmaca, M | 1 |
| Yildirim, H | 1 |
| Ozdemir, H | 1 |
| Koc, M | 1 |
| Ozler, S | 1 |
| Tezcan, E | 1 |
| Kumar, V | 1 |
| Chakrabarti, S | 1 |
| Modi, M | 1 |
| Sahoo, M | 1 |
| Fan, Q | 1 |
| Tan, L | 1 |
| You, C | 1 |
| Wang, J | 1 |
| Ross, CA | 1 |
| Wang, X | 1 |
| Zhang, T | 1 |
| Li, J | 1 |
| Chen, K | 1 |
| Xiao, Z | 1 |
| Bédard, MJ | 1 |
| Chantal, S | 1 |
| Besiroglu, L | 1 |
| Sozen, M | 1 |
| Ozbebit, O | 1 |
| Avcu, S | 1 |
| Selvi, Y | 1 |
| Bora, A | 1 |
| Atli, A | 1 |
| Unal, O | 1 |
| Bulut, MD | 1 |
| Yalçın, O | 1 |
| Sener, S | 1 |
| Konuş Boyunağa, OL | 1 |
| Sarıpınar, EG | 1 |
| Oğur, T | 1 |
| Güney, E | 1 |
| Akın Sarı, B | 1 |
| Işeri, E | 1 |
| Andrés, S | 1 |
| Junqué, C | 1 |
| Castro-Fornieles, J | 1 |
| Whiteside, SP | 2 |
| Abramowitz, JS | 2 |
| Port, JD | 2 |
| Zurowski, B | 1 |
| Kordon, A | 1 |
| Weber-Fahr, W | 1 |
| Voderholzer, U | 1 |
| Kuelz, AK | 1 |
| Freyer, T | 1 |
| Wahl, K | 1 |
| Büchel, C | 1 |
| Hohagen, F | 2 |
| Aoki, Y | 1 |
| Aoki, A | 1 |
| Suwa, H | 1 |
| O'Neill, J | 1 |
| Gorbis, E | 1 |
| Feusner, JD | 1 |
| Yip, JC | 1 |
| Chang, S | 1 |
| Maidment, KM | 1 |
| Levitt, JG | 1 |
| Salamon, N | 1 |
| Ringman, JM | 1 |
| Saxena, S | 1 |
| Russell, A | 2 |
| Cortese, B | 1 |
| Lorch, E | 1 |
| Ivey, J | 2 |
| Banerjee, SP | 2 |
| Moore, GJ | 4 |
| Rosenberg, DR | 4 |
| Alkan, A | 1 |
| Kutlu, R | 1 |
| Kocak, G | 1 |
| Sigirci, A | 1 |
| Emul, M | 1 |
| Dogan, S | 1 |
| Aslan, M | 1 |
| Sarac, K | 1 |
| Yakinci, C | 1 |
| Mirza, Y | 1 |
| Tang, J | 1 |
| Smith, JM | 1 |
| Bhandari, R | 1 |
| Rose, M | 1 |
| Boyd, C | 1 |
| Jang, JH | 1 |
| Kwon, JS | 1 |
| Jang, DP | 1 |
| Moon, WJ | 1 |
| Lee, JM | 1 |
| Ha, TH | 1 |
| Chung, EC | 1 |
| Kim, IY | 1 |
| Kim, SI | 1 |
| Kitamura, H | 1 |
| Shioiri, T | 1 |
| Kimura, T | 1 |
| Ohkubo, M | 1 |
| Nakada, T | 1 |
| Someya, T | 1 |
| Sumitani, S | 1 |
| Harada, M | 1 |
| Kubo, H | 1 |
| Ohmori, T | 1 |
| Oner, O | 1 |
| Devrimci-Ozguven, H | 1 |
| Oktem, F | 1 |
| Yagmurlu, B | 1 |
| Baskak, B | 1 |
| Munir, KM | 1 |
| Mohamed, MA | 1 |
| Smith, MA | 1 |
| Schlund, MW | 1 |
| Nestadt, G | 1 |
| Barker, PB | 1 |
| Hoehn-Saric, R | 1 |
| Kraft, S | 1 |
| Kemmer, C | 1 |
| Meyer, J | 1 |
| Yücel, M | 1 |
| Wood, SJ | 1 |
| Wellard, RM | 1 |
| Harrison, BJ | 1 |
| Fornito, A | 1 |
| Pujol, J | 1 |
| Velakoulis, D | 1 |
| Pantelis, C | 1 |
| Ebert, D | 1 |
| Speck, O | 1 |
| König, A | 1 |
| Berger, M | 1 |
| Hennig, J | 1 |
| Bartha, R | 1 |
| Stein, MB | 1 |
| Williamson, PC | 1 |
| Drost, DJ | 1 |
| Neufeld, RW | 1 |
| Carr, TJ | 1 |
| Canaran, G | 1 |
| Densmore, M | 1 |
| Anderson, G | 1 |
| Siddiqui, AR | 1 |
| Rauch, SL | 1 |
| Fitzgerald, KD | 1 |
| Paulson, LA | 1 |
| Stewart, CM | 1 |
| Amponsah, A | 1 |
| Sullivan, A | 1 |
| MacMillan, S | 1 |
1 review available for aspartic acid and Obsessive-Compulsive Disorder
| Article | Year |
|---|---|
Reduction of N-acetylaspartate in the medial prefrontal cortex correlated with symptom severity in obsessive-compulsive disorder: meta-analyses of (1)H-MRS studies.
Topics: Aspartic Acid; Basal Ganglia; Humans; Magnetic Resonance Spectroscopy; Obsessive-Compulsive Disorder | 2012 |
2 trials available for aspartic acid and Obsessive-Compulsive Disorder
| Article | Year |
|---|---|
Localized functional neurochemical marker abnormalities in dorsolateral prefrontal cortex in pediatric obsessive-compulsive disorder.
Topics: Adolescent; Aspartic Acid; Biomarkers; Child; Choline; Creatine; Female; Humans; Image Interpretatio | 2003 |
Brain MR spectroscopy in children with a history of rheumatic fever with a special emphasis on neuropsychiatric complications.
Topics: Adolescent; Analysis of Variance; Aspartic Acid; Basal Ganglia; Child; Child, Preschool; Choline; Ch | 2004 |
35 other studies available for aspartic acid and Obsessive-Compulsive Disorder
| Article | Year |
|---|---|
Spectroscopic abnormalities in the pregenual anterior cingulate cortex in obsessive-compulsive disorder using proton magnetic resonance spectroscopy: a controlled study.
Topics: Aspartic Acid; Creatine; Glutamine; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Imaging; Obs | 2023 |
Magnetic Resonance Spectroscopy (MRS) and Positron Emission Tomography (PET) Imaging in Obsessive-Compulsive Disorder.
Topics: Aspartic Acid; Creatine; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spect | 2021 |
Striatal structure and its association with N-Acetylaspartate and glutamate in autism spectrum disorder and obsessive compulsive disorder.
Topics: Adolescent; Aspartic Acid; Autism Spectrum Disorder; Child; Corpus Striatum; Female; Functional Late | 2018 |
Associations of neurofunctional, morphometric and metabolic abnormalities with clinical symptom severity and recognition deficit in obsessive-compulsive disorder.
Topics: Adult; Aspartic Acid; Brain; Brain Mapping; Case-Control Studies; Choline; Creatine; Female; Glutami | 2018 |
Proton magnetic resonance spectroscopy in obsessive-compulsive disorder: evidence for reduced neuronal integrity in the anterior cingulate.
Topics: Adult; Aspartic Acid; Caudate Nucleus; Choline; Creatine; Female; Gyrus Cinguli; Humans; Inositol; M | 2014 |
1H-magnetic resonance spectroscopy in obsessive-compulsive disorder: effects of 12 weeks of sertraline treatment on brain metabolites.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Choline; Creatine; Female; Follow-Up Studies; Hum | 2015 |
1H-MRS of the anterior cingulate cortex in childhood and adolescent obsessive-compulsive disorder: a case-control study.
Topics: Adolescent; Aspartic Acid; Case-Control Studies; Child; Female; Glutamic Acid; Glutamine; Gyrus Cing | 2015 |
Metabolic abnormality in the right dorsolateral prefrontal cortex in patients with obsessive-compulsive disorder: proton magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Choline; Female; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Aci | 2017 |
1H magnetic resonance spectroscopy evidence for occipital involvement in treatment-naive paediatric obsessive-compulsive disorder.
Topics: Adolescent; Aspartic Acid; Brain; Child; Choline; Female; Humans; Inositol; Male; Obsessive-Compulsi | 2017 |
A 1H magnetic resonance spectroscopy study in adults with obsessive compulsive disorder: relationship between metabolite concentrations and symptom severity.
Topics: Adult; Aspartic Acid; Brain; Brain Mapping; Case-Control Studies; Choline; Creatine; Female; Glutami | 2008 |
SNAP-25 genotype influences NAA/Cho in left hippocampus.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; DNA; Female; Genotype; Hippocampus; Humans; Magneti | 2008 |
Neurochemistry of the hippocampus in patients with obsessive-compulsive disorder.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Choline; Creatine; Female; Functional Laterality; | 2009 |
Late-onset obsessive compulsive disorder associated with possible gliomatosis cerebri.
Topics: Aged; Anticonvulsants; Aspartic Acid; Brain Neoplasms; Choline; Corpus Callosum; Dominance, Cerebral | 2009 |
Increased N-Acetylaspartate/creatine ratio in the medial prefrontal cortex among unmedicated obsessive-compulsive disorder patients.
Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Diagnostic and Statistical Manual of Mental Dis | 2010 |
Brain magnetic resonance spectroscopy in obsessive-compulsive disorder: the importance of considering subclinical symptoms of anxiety and depression.
Topics: Adult; Anxiety; Aspartic Acid; Brain; Brain Mapping; Choline; Creatine; Depression; Female; Function | 2011 |
The involvement of distinct neural systems in patients with obsessive-compulsive disorder with autogenous and reactive obsessions.
Topics: Adult; Aspartic Acid; Choline; Creatine; Diagnostic and Statistical Manual of Mental Disorders; Drug | 2011 |
Comparing brain magnetic resonance spectroscopy findings of pediatric treatment-naive obsessive-compulsive disorder patients with healthy controls.
Topics: Adolescent; Aspartic Acid; Brain; Case-Control Studies; Child; Female; Humans; Magnetic Resonance Im | 2011 |
Proton magnetic resonance spectroscopy in pediatric obsessive-compulsive disorder: longitudinal study before and after treatment.
Topics: Adolescent; Aspartic Acid; Behavior Therapy; Brain; Child; Choline; Creatine; Female; Follow-Up Stud | 2012 |
The effect of behavior therapy on caudate N-acetyl-l-aspartic acid in adults with obsessive-compulsive disorder.
Topics: Adult; Aspartic Acid; Behavior Therapy; Caudate Nucleus; Female; Humans; Magnetic Resonance Spectros | 2012 |
Relevance of orbitofrontal neurochemistry for the outcome of cognitive-behavioural therapy in patients with obsessive-compulsive disorder.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Cognitive Behavioral Therapy; Creatine; Female; Humans; Magn | 2012 |
Decreased caudate N-acetyl-l-aspartic acid in pediatric obsessive-compulsive disorder and the effects of behavior therapy.
Topics: Adolescent; Aspartic Acid; Behavior Therapy; Caudate Nucleus; Child; Female; Gyrus Cinguli; Humans; | 2012 |
Effects of intensive cognitive-behavioral therapy on cingulate neurochemistry in obsessive-compulsive disorder.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Choline; Cognitive Behavioral Therapy; Dipeptides | 2013 |
Reduced anterior cingulate glutamatergic concentrations in childhood OCD and major depression versus healthy controls.
Topics: Adolescent; Aspartic Acid; Child; Choline; Creatine; Depressive Disorder, Major; Female; Glutamic Ac | 2004 |
A proton MRSI study of brain N-acetylaspartate level after 12 weeks of citalopram treatment in drug-naive patients with obsessive-compulsive disorder.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Choline; Citalopram; Creatine; Female; Frontal Lobe; G | 2006 |
Parietal white matter abnormalities in obsessive-compulsive disorder: a magnetic resonance spectroscopy study at 3-Tesla.
Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy | 2006 |
Proton magnetic resonance spectroscopy reveals an abnormality in the anterior cingulate of a subgroup of obsessive-compulsive disorder patients.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Basal Ganglia; Benzodiazepines; Dominance, Cerebral; Dos | 2007 |
Proton MR spectroscopy: higher right anterior cingulate N-acetylaspartate/choline ratio in Asperger syndrome compared with healthy controls.
Topics: Adolescent; Adult; Aspartic Acid; Asperger Syndrome; Choline; Diagnostic and Statistical Manual of M | 2007 |
Proton magnetic resonance spectroscopy in obsessive-compulsive disorder: a pilot investigation comparing treatment responders and non-responders.
Topics: Adult; Aspartic Acid; Basal Ganglia; Choline; Creatine; Dominance, Cerebral; Energy Metabolism; Fema | 2007 |
Dopamine transporter genotype influences N-acetyl-aspartate in the left putamen.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dominance, Cerebral; Dopamine Plasma Memb | 2009 |
Anterior cingulate glutamate-glutamine levels predict symptom severity in women with obsessive-compulsive disorder.
Topics: Adult; Aspartic Acid; Biomarkers; Choline; Creatine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli | 2008 |
1H-magnetic resonance spectroscopy in obsessive-compulsive disorder: evidence for neuronal loss in the cingulate gyrus and the right striatum.
Topics: Adult; Aspartic Acid; Cell Count; Corpus Striatum; Female; Functional Laterality; Gyrus Cinguli; Hum | 1997 |
A short echo 1H spectroscopy and volumetric MRI study of the corpus striatum in patients with obsessive-compulsive disorder and comparison subjects.
Topics: Adult; Aspartic Acid; Cell Count; Corpus Striatum; Female; Functional Laterality; Humans; Hydrogen; | 1998 |
Neuroimaging research and the neurobiology of obsessive-compulsive disorder: where do we go from here?
Topics: Adolescent; Aspartic Acid; Brain Mapping; Cerebral Cortex; Child; Corpus Striatum; Female; Humans; M | 2000 |
Proton spectroscopic imaging of the thalamus in treatment-naive pediatric obsessive-compulsive disorder.
Topics: Adolescent; Aspartic Acid; Brain Mapping; Case-Control Studies; Cerebral Cortex; Child; Choline; Cor | 2000 |
Increased medial thalamic choline in pediatric obsessive-compulsive disorder as detected by quantitative in vivo spectroscopic imaging.
Topics: Adolescent; Aspartic Acid; Brain Mapping; Case-Control Studies; Child; Choline; Creatine; Cytosol; D | 2001 |