Page last updated: 2024-11-08

aspartic acid and Obesity

aspartic acid has been researched along with Obesity in 25 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"Glycogen levels were also lower in this region."5.36Obesity and type 2 diabetes in rats are associated with altered brain glycogen and amino-acid homeostasis. ( Benie, AJ; Bouman, SD; Schousboe, A; Sickmann, HM; Waagepetersen, HS, 2010)
"Higher triglyceride and lower HDL levels statistically account for the association between BMI and myo-inositol, pointing toward a potentially critical role for dyslipidemia in the development of cerebral neurochemical alterations in obesity."3.79Dyslipidemia links obesity to early cerebral neurochemical alterations. ( Gonzales, MM; Haley, AP; Tanaka, H; Tarumi, T, 2013)
"This study was undertaken to determine whether changes in muscle mass, muscle fiber diameter, or shifts in fiber type occur in the aspartic acid-injected rat, an animal model of hypothalamically induced obesity."3.67Characterization of muscles from aspartic acid obese rats. ( Burbach, JA; Goldman, M; Schlenker, EH, 1985)
"Glycogen levels were also lower in this region."1.36Obesity and type 2 diabetes in rats are associated with altered brain glycogen and amino-acid homeostasis. ( Benie, AJ; Bouman, SD; Schousboe, A; Sickmann, HM; Waagepetersen, HS, 2010)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19905 (20.00)18.7374
1990's1 (4.00)18.2507
2000's9 (36.00)29.6817
2010's7 (28.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Zhang, J1
Xian, TZ1
Wu, MX1
Li, C1
Wang, W1
Man, F1
Zhang, X1
Wang, X1
Pan, Q1
Guo, L1
Teymoori, F1
Asghari, G1
Hoseinpour, S1
Roosta, S1
Bordbar, M1
Mirmiran, P1
Sarbazi, N1
Azizi, F1
Boutin, JA1
Jullian, M1
Frankiewicz, L1
Galibert, M1
Gloanec, P1
Le Diguarher, T1
Dupuis, P1
Ko, A1
Ripoll, L1
Bertrand, M1
Pecquery, A1
Ferry, G1
Puget, K1
Bond, DJ1
Silveira, LE1
MacMillan, EL1
Torres, IJ1
Lang, DJ1
Su, W1
Honer, WG1
Lam, RW1
Yatham, LN1
Yashiro, H1
Hamagami, K1
Hiyoshi, H1
Sugama, J1
Tsuchimori, K1
Yamaguchi, F1
Moritoh, Y1
Sasaki, M2
Maekawa, T1
Yamada, Y1
Watanabe, M1
Haley, AP2
Gonzales, MM2
Tarumi, T2
Tanaka, H2
Auer, MK1
Sack, M1
Lenz, JN1
Jakovcevski, M1
Biedermann, SV1
Falfán-Melgoza, C1
Deussing, J1
Steinle, J1
Bielohuby, M1
Bidlingmaier, M1
Pfister, F1
Stalla, GK1
Ende, G1
Weber-Fahr, W1
Fuss, J1
Gass, P1
Ouederni, TB1
Sanchez-Corona, J1
Flores Martinez, SE1
Ben Maiz, H1
Skhiri, HA1
Abid, HK1
Benammar-Elgaaied, A1
Barfield, E1
Liu, YH1
Kessler, M1
Pawelczak, M1
David, R1
Shah, B1
Sickmann, HM1
Waagepetersen, HS1
Schousboe, A1
Benie, AJ1
Bouman, SD1
Paradossi, U1
Manfrini, O1
Ciofini, E1
Pizzi, C1
Biagini, A1
Xhyheri, B1
Colombo, MG1
Eagan, DE1
Vaghasia, M1
Stefan, N1
Kovacs, P1
Stumvoll, M2
Hanson, RL1
Lehn-Stefan, A1
Permana, PA1
Baier, LJ1
Tataranni, PA1
Silver, K1
Bogardus, C1
Cousin, P1
Calemard-Michel, L1
Lejeune, H1
Raverot, G1
Yessaad, N1
Emptoz-Bonneton, A1
Morel, Y1
Pugeat, M1
Chen, MW1
Yang, MG1
Wang, CJ1
Wang, YM1
Xu, XP1
Liu, SQ1
Zhang, Q1
Sun, HY1
Kim, HC1
Kang, DR1
Nam, CM1
Hur, NW1
Shim, JS1
Jee, SH1
Suh, I1
Surendran, S1
Matalon, R1
Tyring, SK1
Plazzi, G1
Parmeggiani, A1
Mignot, E1
Lin, L1
Scano, MC1
Posar, A1
Bernardi, F1
Lodi, R1
Tonon, C1
Barbiroli, B1
Montagna, P1
Cicognani, A1
Raber, J1
Wahl, HG1
Jacob, S1
Rettig, A1
Machicao, F1
Häring, H1
Higuchi, N1
Arai, T1
Oki, Y1
Burbach, JA1
Schlenker, EH1
Goldman, M1
Schainker, B1
Olney, JW1
Gylfe, E1
Chakrabarty, K1
Leveille, GA1

Reviews

1 review available for aspartic acid and Obesity

ArticleYear
Detrimental effects of chronic hypothalamic-pituitary-adrenal axis activation. From obesity to memory deficits.
    Molecular neurobiology, 1998, Volume: 18, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adrenocorticotropic Hormone; Amygdala; Animals; Arginine Vasopre

1998

Trials

1 trial available for aspartic acid and Obesity

ArticleYear
Comparing the effects of twice-daily exenatide and insulin on renal function in patients with type 2 diabetes mellitus: secondary analysis of a randomized controlled trial.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2022, Volume: 70, Issue:7

    Topics: Aspartic Acid; Diabetes Mellitus, Type 2; Exenatide; Glucagon-Like Peptide-1 Receptor; Glycated Hemo

2022

Other Studies

23 other studies available for aspartic acid and Obesity

ArticleYear
Dietary amino acids and anthropometric indices: Tehran Lipid and Glucose Study.
    Archives of endocrinology and metabolism, 2023, Jun-19, Volume: 67, Issue:6

    Topics: Adult; Amino Acids; Aspartic Acid; Body Mass Index; Cysteine; Glutamates; Humans; Iran; Lipids; Lysi

2023
MCH-R1 Antagonist GPS18169, a Pseudopeptide, Is a Peripheral Anti-Obesity Agent in Mice.
    Molecules (Basel, Switzerland), 2021, Feb-27, Volume: 26, Issue:5

    Topics: Adipose Tissue; Alkynes; Aminobutyrates; Animals; Anti-Obesity Agents; Appetite; Aspartic Acid; Dise

2021
Diagnosis and body mass index effects on hippocampal volumes and neurochemistry in bipolar disorder.
    Translational psychiatry, 2017, 03-28, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Body Mass Index; Brain; Case-Control Studies; Cr

2017
SCO-792, an enteropeptidase inhibitor, improves disease status of diabetes and obesity in mice.
    Diabetes, obesity & metabolism, 2019, Volume: 21, Issue:10

    Topics: Animals; Aspartic Acid; Benzofurans; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Di

2019
Dyslipidemia links obesity to early cerebral neurochemical alterations.
    Obesity (Silver Spring, Md.), 2013, Volume: 21, Issue:10

    Topics: Adult; Aspartic Acid; Blood Glucose; Blood Pressure; Body Mass Index; Brain; Brain Diseases; Cholest

2013
Effects of a high-caloric diet and physical exercise on brain metabolite levels: a combined proton MRS and histologic study.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2015, Mar-31, Volume: 35, Issue:4

    Topics: Animals; Aspartic Acid; Brain; Carbohydrate Metabolism; Diet; Dipeptides; Energy Intake; Fatty Acids

2015
The G1057D polymorphism of IRS-2 gene is not associated with type 2 diabetes and obese patients among ethnic groups in Tunisian population.
    Clinical biochemistry, 2009, Volume: 42, Issue:10-11

    Topics: Aspartic Acid; Black People; Diabetes Mellitus, Type 2; Ethnicity; Female; Genetic Predisposition to

2009
The prevalence of abnormal liver enzymes and metabolic syndrome in obese adolescent females with polycystic ovary syndrome.
    Journal of pediatric and adolescent gynecology, 2009, Volume: 22, Issue:5

    Topics: Adolescent; Alanine Transaminase; Aspartic Acid; Child; Cross-Sectional Studies; Fatty Liver; Female

2009
Obesity and type 2 diabetes in rats are associated with altered brain glycogen and amino-acid homeostasis.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2010, Volume: 30, Issue:8

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood Glucose; Brain; Diabetes Mellitus, Type 2; gamma

2010
Weight is an independent predictor of vascular injury in healthy volunteers with aspartate allele.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2012, Volume: 13, Issue:5

    Topics: Adult; Aspartic Acid; Atherosclerosis; Body Weight; Brachial Artery; Carotid Artery Diseases; Caroti

2012
Indirect effects of elevated body mass index on memory performance through altered cerebral metabolite concentrations.
    Psychosomatic medicine, 2012, Volume: 74, Issue:7

    Topics: Adult; Aspartic Acid; Biomarkers; Body Mass Index; Brain; Choline; Cognition Disorders; Creatine; Fe

2012
Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity.
    Diabetes, 2003, Volume: 52, Issue:6

    Topics: Adult; Amino Acid Substitution; Animals; Arizona; Aspartic Acid; Base Sequence; Body Composition; Co

2003
Influence of SHBG gene pentanucleotide TAAAA repeat and D327N polymorphism on serum sex hormone-binding globulin concentration in hirsute women.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:2

    Topics: Adult; Alleles; Asparagine; Aspartic Acid; Body Mass Index; Female; Gene Frequency; Hirsutism; Homoz

2004
[Study on the association of PPP1R3 gene polymorphism with type 2 diabetes in Han population of Anhui province].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2004, Volume: 25, Issue:6

    Topics: Adult; Alleles; Aspartic Acid; China; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; H

2004
Elevated serum aminotransferase level as a predictor of intracerebral hemorrhage: Korea medical insurance corporation study.
    Stroke, 2005, Volume: 36, Issue:8

    Topics: Adult; Alanine Transaminase; Aspartic Acid; Blood Pressure; Brain Ischemia; Cerebral Hemorrhage; Fem

2005
Upregulation of aspartoacylase activity in the duodenum of obesity induced diabetes mouse: implications on diabetic neuropathy.
    Biochemical and biophysical research communications, 2006, Jul-07, Volume: 345, Issue:3

    Topics: Amidohydrolases; Animals; Aspartic Acid; Brain; Diabetes Mellitus, Experimental; Diabetic Neuropathi

2006
Narcolepsy-cataplexy associated with precocious puberty.
    Neurology, 2006, May-23, Volume: 66, Issue:10

    Topics: Aspartic Acid; Benzhydryl Compounds; Cataplexy; Child; Creatine; Cyclohexanols; Disorders of Excessi

2006
Two novel prevalent polymorphisms in the hormone-sensitive lipase gene have no effect on insulin sensitivity of lipolysis and glucose disposal.
    Journal of lipid research, 2001, Volume: 42, Issue:11

    Topics: Adult; Alleles; Aspartic Acid; Blood Glucose; Exons; Fatty Acids, Nonesterified; Female; Glucose Cla

2001
[Effect of androgen on the onset of diabetes in the KK mice treated with monosodium aspartate].
    Jikken dobutsu. Experimental animals, 1989, Volume: 38, Issue:1

    Topics: Age Factors; Androgens; Animals; Aspartic Acid; Blood Glucose; Castration; Dehydroepiandrosterone; D

1989
Characterization of muscles from aspartic acid obese rats.
    The American journal of physiology, 1985, Volume: 249, Issue:1 Pt 2

    Topics: Age Factors; Animals; Aspartic Acid; Body Weight; Diaphragm; Female; Male; Mice; Mice, Obese; Muscle

1985
Glutamate-type hypothalamic-pituitary syndrome in mice treated with aspartate or cysteate in infancy.
    Journal of neural transmission, 1974, Volume: 35, Issue:3

    Topics: Adipates; Alanine; Amino Acids, Dicarboxylic; Amino Acids, Sulfur; Animals; Animals, Newborn; Aspart

1974
Changes of free amino acids in pancreatic beta-cells after starvation and substrate deprivation.
    Acta endocrinologica, 1974, Volume: 75, Issue:1

    Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Carbon Radioisotopes; Chromatography,

1974
Conversion of pyruvate to glyceride-glycerol in adipose tissue of obese and nonobese mice.
    Archives of biochemistry and biophysics, 1968, Volume: 125, Issue:1

    Topics: Adipose Tissue; Animals; Aspartic Acid; Carbon Isotopes; Carboxy-Lyases; Female; Glycerides; Glycero

1968