Page last updated: 2024-11-08

aspartic acid and Neuralgia

aspartic acid has been researched along with Neuralgia in 11 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research Excerpts

ExcerptRelevanceReference
" A 61-year-old man presented with severe cognitive dysfunction after long-term methadone treatment for intercostal neuralgia and was diagnosed with GH insufficiency by GH releasing hormone-arginine testing."3.80Recombinant human growth hormone improves cognitive capacity in a pain patient exposed to chronic opioids. ( Gordh, T; Grönbladh, A; Nyberg, F; Ortiz-Nieto, F; Raininko, R; Rhodin, A; Skottheim, B; von Ehren, M, 2014)
"The number of patients with diabetic neuropathic pain (DNP) continues to increase, but available treatments are limited."1.72Reactive Oxygen Species Contributes to Type 2 Diabetic Neuropathic Pain via the Thioredoxin-Interacting Protein-NOD-Like Receptor Protein 3- N -Methyl-D-Aspartic Acid Receptor 2B Pathway. ( Cao, H; Li, J; Li, X; Luo, GH; Wang, JW; Wei, N; Wu, SS; Ye, XY; Zhang, ZH, 2022)
"Although neuropathic pain is a common consequence after CNS injuries, little attention has been given to neuropathic pain symptoms after TBI."1.43Subacute Pain after Traumatic Brain Injury Is Associated with Lower Insular N-Acetylaspartate Concentrations. ( Adcock, JP; Govind, V; Levin, BE; Maudsley, AA; Widerström-Noga, E, 2016)
"SNI mice developed mechanical allodynia and motor coordination impairment 30 days after SNI surgery."1.43D-Aspartate drinking solution alleviates pain and cognitive impairment in neuropathic mice. ( D'Aniello, A; de Bartolomeis, A; de Novellis, V; Guida, F; Iannotta, M; Luongo, L; Maione, S; Marabese, I; Marmo, F; Palazzo, E; Romano, R; Rossi, F; Stella, L; Usiello, A, 2016)
"More specifically, the presence of neuropathic pain after spinal cord injury is associated with significant reductions in thalamic N-acetylaspartate, gamma amino butyric acid content, and blood flow in the region of the thalamic reticular nucleus."1.40Thalamic activity and biochemical changes in individuals with neuropathic pain after spinal cord injury. ( Edden, RAE; Gustin, SM; Henderson, LA; McIndoe, L; Rae, CD; Siddall, PJ; Wilcox, SL; Wrigley, PJ; Youssef, AM, 2014)
"Gabapentin is an anticonvulsant that successfully treats many neuropathic pain syndromes, although the mechanism of its antihyperalgesic action remains elusive."1.33Evidence that gabapentin reduces neuropathic pain by inhibiting the spinal release of glutamate. ( Coderre, TJ; Kumar, N; Lefebvre, CD; Yu, JS, 2005)
"Our results using (1)H-MRS suggest that neuropathic pain seems to be associated with an abnormal balance of the neural activity in the thalamus."1.33N-Acetylaspartate concentrations in the thalami of neuropathic pain patients and healthy comparison subjects measured with (1)H-MRS. ( Fukui, S; Inubushi, T; Matsuno, M; Nosaka, S, 2006)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's4 (36.36)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Wang, JW1
Ye, XY1
Wei, N1
Wu, SS1
Zhang, ZH1
Luo, GH1
Li, X1
Li, J1
Cao, H1
Medeiros, P1
de Freitas, RL1
Boccella, S1
Iannotta, M2
Belardo, C1
Mazzitelli, M1
Romano, R2
De Gregorio, D1
Coimbra, NC1
Palazzo, E2
Maione, S2
Wang, Z1
Huang, S1
Yu, X1
Li, L1
Yang, M1
Liang, S1
Liu, W1
Tao, J1
Gustin, SM1
Wrigley, PJ1
Youssef, AM1
McIndoe, L1
Wilcox, SL1
Rae, CD1
Edden, RAE1
Siddall, PJ1
Henderson, LA1
Rhodin, A1
von Ehren, M1
Skottheim, B1
Grönbladh, A1
Ortiz-Nieto, F1
Raininko, R1
Gordh, T1
Nyberg, F1
Widerström-Noga, E1
Govind, V1
Adcock, JP1
Levin, BE1
Maudsley, AA1
Luongo, L1
Guida, F1
Marabese, I1
Rossi, F1
D'Aniello, A1
Stella, L1
Marmo, F1
Usiello, A1
de Bartolomeis, A1
de Novellis, V1
Ma, C1
Li, CX1
Yi, JL1
Yan, LP1
Coderre, TJ1
Kumar, N1
Lefebvre, CD1
Yu, JS1
Fukui, S1
Matsuno, M1
Inubushi, T1
Nosaka, S1
Mertens, P1
Ghaemmaghami, C1
Bert, L1
Perret-Liaudet, A1
Sindou, M1
Renaud, B1

Other Studies

11 other studies available for aspartic acid and Neuralgia

ArticleYear
Reactive Oxygen Species Contributes to Type 2 Diabetic Neuropathic Pain via the Thioredoxin-Interacting Protein-NOD-Like Receptor Protein 3- N -Methyl-D-Aspartic Acid Receptor 2B Pathway.
    Anesthesia and analgesia, 2022, 10-01, Volume: 135, Issue:4

    Topics: Animals; Aspartic Acid; Caspases; Cell Cycle Proteins; Diabetes Mellitus, Experimental; Diabetes Mel

2022
Characterization of the sensory, affective, cognitive, biochemical, and neuronal alterations in a modified chronic constriction injury model of neuropathic pain in mice.
    Journal of neuroscience research, 2020, Volume: 98, Issue:2

    Topics: Animals; Aspartic Acid; Behavior, Animal; Brain; Cognition; gamma-Aminobutyric Acid; Male; Mice; Neu

2020
Altered thalamic neurotransmitters metabolism and functional connectivity during the development of chronic constriction injury induced neuropathic pain.
    Biological research, 2020, Aug-26, Volume: 53, Issue:1

    Topics: Animals; Aspartic Acid; Constriction; Glutamic Acid; Hyperalgesia; Neuralgia; Neurotransmitter Agent

2020
Thalamic activity and biochemical changes in individuals with neuropathic pain after spinal cord injury.
    Pain, 2014, Volume: 155, Issue:5

    Topics: Adult; Aged; Aspartic Acid; Female; Functional Neuroimaging; Humans; Magnetic Resonance Imaging; Mag

2014
Recombinant human growth hormone improves cognitive capacity in a pain patient exposed to chronic opioids.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:6

    Topics: Apoptosis; Arginine; Aspartic Acid; Cognition Disorders; Creatine; Growth Hormone; Growth Hormone-Re

2014
Subacute Pain after Traumatic Brain Injury Is Associated with Lower Insular N-Acetylaspartate Concentrations.
    Journal of neurotrauma, 2016, 07-15, Volume: 33, Issue:14

    Topics: Adult; Age Factors; Aspartic Acid; Brain Injuries, Traumatic; Cerebral Cortex; Creatine; Female; Hum

2016
D-Aspartate drinking solution alleviates pain and cognitive impairment in neuropathic mice.
    Amino acids, 2016, Volume: 48, Issue:7

    Topics: Animals; Aspartic Acid; Cognitive Dysfunction; Disks Large Homolog 4 Protein; Homer Scaffolding Prot

2016
[Effects of electroacupuncture on glutamate and aspartic acid contents in the dorsal root ganglion and spinal cord in rats with neuropathic pain].
    Zhen ci yan jiu = Acupuncture research, 2008, Volume: 33, Issue:4

    Topics: Acupuncture Analgesia; Animals; Aspartic Acid; Electroacupuncture; Female; Ganglia, Spinal; Glutamic

2008
Evidence that gabapentin reduces neuropathic pain by inhibiting the spinal release of glutamate.
    Journal of neurochemistry, 2005, Volume: 94, Issue:4

    Topics: Amines; Analgesics; Animals; Aspartic Acid; Chronic Disease; Cyclohexanecarboxylic Acids; Excitatory

2005
N-Acetylaspartate concentrations in the thalami of neuropathic pain patients and healthy comparison subjects measured with (1)H-MRS.
    Magnetic resonance imaging, 2006, Volume: 24, Issue:1

    Topics: Adult; Aged; Aspartic Acid; Case-Control Studies; Choline; Creatine; Female; Humans; Linear Models;

2006
Amino acids in spinal dorsal horn of patients during surgery for neuropathic pain or spasticity.
    Neuroreport, 2000, Jun-05, Volume: 11, Issue:8

    Topics: Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Extracellular Space; Feasibility S

2000