aspartic acid has been researched along with Necrosis in 58 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "OC-108 is a novel sclerosing agent for hemorrhoids, containing aluminum potassium sulfate (alum) and tannic acid as its main ingredients." | 7.73 | Sclerosing effect of OC-108, a novel agent for hemorrhoids, is associated with granulomatous inflammation induced by aluminum. ( Goto, K; Iwasaki, S; Komatsu, H; Ono, T; Takagi, S, 2005) |
| " L-2-Chloropropionic acid (L-CPA) produces selective neuronal cell necrosis in rat cerebellum when administered orally at 750 mg kg-1 that is mediated in part through activation of N-methyl-D-aspartate (NMDA) receptors." | 7.69 | Possible role of nitric oxide in the development of L-2-chloropropionic acid-induced cerebellar granule cell necrosis. ( Dunn, D; Farnworth, M; Gyte, A; Lock, EA; Moore, RB; Simpson, MG; Widdowson, PS; Wyatt, I, 1996) |
| "Possible biochemical events involved in L-2-chloropropionic acid (L-CPA)-induced delayed cerebellar granule cell necrosis following N-methyl-D-aspartate activation were studied in vivo." | 7.69 | Calpain activation and not oxidative damage mediates L-2-chloropropionic acid-induced cerebellar granule cell necrosis. ( Coutts, CT; Foster, J; Gyte, A; Upton, R; Widdowson, PS; Wyatt, I, 1997) |
| "We have used the model of L-2-chloropropionic acid (L-CPA)-induced selective cerebellar granule necrosis to study excitatory amino acid-induced necrotic cell death in vivo produced by the activation of N-methyl-D-aspartate (NMDA) receptors." | 7.69 | L-2-chloropropionic acid-induced cerebellar granule cell necrosis is potentiated by L-type calcium channel antagonists. ( Gyte, A; Moores, R; Pitts, M; Smith, JC; Upton, R; Widdowson, PS; Wyatt, I, 1997) |
| "It was concluded that in brain metastases of mammary carcinoma Lact represents a product of ischemia preceding/during tissue decay resulting in central necrosis, rather than tumor specific metabolism resulting in increased glycolysis." | 5.29 | Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma. ( Oudkerk, M; Sijens, PE; van Dijk, P, 1994) |
| " This biochemical information can be processed and presented as density maps of several metabolites, among them N-acetylaspartate (marker of neuronal viability), choline (marker of membrane turnover), creatine (related to the energy state of the cells), myo-Inositol (exclusively found in astrocytes), lipids and lactate (observed in necrosis and other pathological processes) which mean relevant information in the context of brain tumors." | 4.85 | Proton magnetic resonance spectroscopy imaging in the study of human brain cancer. ( Celda, B; Martínez-Bisbal, MC, 2009) |
| "OC-108 is a novel sclerosing agent for hemorrhoids, containing aluminum potassium sulfate (alum) and tannic acid as its main ingredients." | 3.73 | Sclerosing effect of OC-108, a novel agent for hemorrhoids, is associated with granulomatous inflammation induced by aluminum. ( Goto, K; Iwasaki, S; Komatsu, H; Ono, T; Takagi, S, 2005) |
| " L-2-Chloropropionic acid (L-CPA) produces selective neuronal cell necrosis in rat cerebellum when administered orally at 750 mg kg-1 that is mediated in part through activation of N-methyl-D-aspartate (NMDA) receptors." | 3.69 | Possible role of nitric oxide in the development of L-2-chloropropionic acid-induced cerebellar granule cell necrosis. ( Dunn, D; Farnworth, M; Gyte, A; Lock, EA; Moore, RB; Simpson, MG; Widdowson, PS; Wyatt, I, 1996) |
| "Possible biochemical events involved in L-2-chloropropionic acid (L-CPA)-induced delayed cerebellar granule cell necrosis following N-methyl-D-aspartate activation were studied in vivo." | 3.69 | Calpain activation and not oxidative damage mediates L-2-chloropropionic acid-induced cerebellar granule cell necrosis. ( Coutts, CT; Foster, J; Gyte, A; Upton, R; Widdowson, PS; Wyatt, I, 1997) |
| "We have used the model of L-2-chloropropionic acid (L-CPA)-induced selective cerebellar granule necrosis to study excitatory amino acid-induced necrotic cell death in vivo produced by the activation of N-methyl-D-aspartate (NMDA) receptors." | 3.69 | L-2-chloropropionic acid-induced cerebellar granule cell necrosis is potentiated by L-type calcium channel antagonists. ( Gyte, A; Moores, R; Pitts, M; Smith, JC; Upton, R; Widdowson, PS; Wyatt, I, 1997) |
| "Liver necrosis was produced in rats by administering 3 doses of a mixture of carbon tetrachloride + olive oil, 2 ml/kg, ip." | 3.68 | Effect of aspartate and glutamate on carbon tetrachloride induced liver damage in rats. ( Garg, KN; Mehrotra, GC; Singh, J, 1990) |
| "Several authors have recently proposed that excessive calcium (Ca++) influx into postsynaptic cells may be the mechanism by which excitotoxins such as glutamate (Glu), N-methylaspartate (NMA) and kainic acid (KA) cause neuronal necrosis." | 3.67 | Calcium influx accompanies but does not cause excitotoxin-induced neuronal necrosis in retina. ( Labruyere, J; Olney, JW; Price, MT; Samson, L, 1985) |
| " Isoproterenol-induced necrosis of the heart muscle leads to a decrease in both glutamine and alanine ability to bind ammonia (20--40 and 30--45%, respectively)." | 3.66 | [Neutralization of ammonia in cardiac muscle]. ( Minkovskiĭ, EB; Pisarenko, OI; Studneva, IM, 1980) |
| "Postradiation treatment necrosis is one of the most serious late sequelae and appears within 6 months." | 3.01 | Brain magnetic resonance spectroscopy to differentiate recurrent neoplasm from radiation necrosis: A systematic review and meta-analysis. ( Aseel, A; McCarthy, P; Mohammed, A, 2023) |
| "necrosis in patients with primary brain tumors or brain metastasis." | 2.53 | Differentiating Radiation-Induced Necrosis from Recurrent Brain Tumor Using MR Perfusion and Spectroscopy: A Meta-Analysis. ( Chen, YC; Chuang, MT; Liu, YS; Tsai, YS; Wang, CK, 2016) |
| "Bilateral striatal necrosis is usually associated with either endogenous or exogenous toxins, and with poor neurodevelopmental outcomes." | 1.38 | Reversible parainfectious bilateral "striatal necrosis". ( Connolly, DJ; Khan, R; Mordekar, SR; Nandish, S; Rittey, CD, 2012) |
| "The histological diagnosis was anaplastic oligodendroglioma (WHO grade III)." | 1.37 | [Usefulness of quantitative H-MR spectroscopy for the differentiation between radiation necrosis and recurrence of anaplastic oligodendroglioma]. ( Akutsu, H; Anno, I; Isobe, T; Masumoto, T; Matsumura, A; Nakai, K; Shiigai, M; Takano, S; Yamamoto, T, 2011) |
| "Choline (Cho) was increased in 3 (11%), normal in 4 (14%), and reduced in 21 (75%) spectra." | 1.30 | Temporal lobe necrosis following radiation therapy for nasopharyngeal carcinoma: 1H MR spectroscopic findings. ( Aw, YS; Chong, VF; Chua, EJ; Fan, YF; Ho, GL; Rumpel, H, 1999) |
| "It was concluded that in brain metastases of mammary carcinoma Lact represents a product of ischemia preceding/during tissue decay resulting in central necrosis, rather than tumor specific metabolism resulting in increased glycolysis." | 1.29 | Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma. ( Oudkerk, M; Sijens, PE; van Dijk, P, 1994) |
| " The toxic effects of both agonists were prevented if the concentration of calcium in the exposing solution was reduced to 0." | 1.27 | Neurotoxicity of excitatory amino acid receptor agonists in rat cerebellar slices: dependence on calcium concentration. ( Garthwaite, G; Garthwaite, J, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (36.21) | 18.7374 |
| 1990's | 15 (25.86) | 18.2507 |
| 2000's | 15 (25.86) | 29.6817 |
| 2010's | 5 (8.62) | 24.3611 |
| 2020's | 2 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Aseel, A | 1 |
| McCarthy, P | 1 |
| Mohammed, A | 1 |
| Wang, AP | 1 |
| Suryavanshi, T | 1 |
| Marcucci, M | 1 |
| Fong, C | 1 |
| Whitton, AC | 1 |
| Reddy, KKV | 1 |
| Sawai, H | 1 |
| Chuang, MT | 1 |
| Liu, YS | 1 |
| Tsai, YS | 1 |
| Chen, YC | 1 |
| Wang, CK | 1 |
| Wang, C | 1 |
| Chen, H | 1 |
| Zhang, M | 1 |
| Zhang, J | 1 |
| Wei, X | 1 |
| Ying, W | 1 |
| Martínez-Bisbal, MC | 1 |
| Celda, B | 1 |
| Isobe, T | 1 |
| Akutsu, H | 1 |
| Yamamoto, T | 1 |
| Shiigai, M | 1 |
| Masumoto, T | 1 |
| Nakai, K | 1 |
| Takano, S | 1 |
| Anno, I | 1 |
| Matsumura, A | 1 |
| Nandish, S | 1 |
| Khan, R | 1 |
| Connolly, DJ | 1 |
| Rittey, CD | 1 |
| Mordekar, SR | 1 |
| MASUDA, M | 1 |
| KUZUDANI, A | 1 |
| MORI, K | 1 |
| OGASAWARA, K | 1 |
| IRINO, J | 1 |
| TABUCHI, K | 1 |
| TOMIKAWA, J | 1 |
| INOUE, H | 1 |
| NAKANO, K | 1 |
| ADACHI, H | 1 |
| KANETSUNA, H | 1 |
| Herynek, V | 1 |
| Burian, M | 1 |
| Jirák, D | 1 |
| Liscák, R | 1 |
| Námestková, K | 1 |
| Hájek, M | 1 |
| Syková, E | 1 |
| Ono, T | 1 |
| Goto, K | 1 |
| Takagi, S | 1 |
| Iwasaki, S | 1 |
| Komatsu, H | 1 |
| Bonde, C | 1 |
| Noraberg, J | 1 |
| Noer, H | 1 |
| Zimmer, J | 1 |
| Harukuni, I | 1 |
| Bhardwaj, A | 1 |
| Roy, MK | 1 |
| Takenaka, M | 1 |
| Kobori, M | 1 |
| Nakahara, K | 1 |
| Isobe, S | 1 |
| Tsushida, T | 1 |
| Williams, JA | 1 |
| Barreiro, CJ | 1 |
| Nwakanma, LU | 1 |
| Lange, MS | 1 |
| Kratz, LE | 1 |
| Blue, ME | 1 |
| Berrong, J | 1 |
| Patel, ND | 1 |
| Gott, VL | 1 |
| Troncoso, JC | 1 |
| Johnston, MV | 1 |
| Baumgartner, WA | 1 |
| Gao, HK | 1 |
| Zhou, ZG | 1 |
| Li, Y | 1 |
| Chen, YQ | 1 |
| Karagulle Kendi, AT | 1 |
| Krenzel, C | 1 |
| Ott, FW | 1 |
| Brace, JR | 1 |
| Norberg, SK | 1 |
| Kieffer, SA | 1 |
| Alexander, NM | 1 |
| Scheig, R | 1 |
| Klatskin, G | 1 |
| Finkelstein, MW | 3 |
| Daabees, TT | 3 |
| Stegink, LD | 4 |
| Applebaum, AE | 3 |
| Pisarenko, OI | 1 |
| Minkovskiĭ, EB | 1 |
| Studneva, IM | 1 |
| Sijens, PE | 1 |
| van Dijk, P | 1 |
| Oudkerk, M | 1 |
| Xu, CQ | 1 |
| Li, LX | 1 |
| Wang, ZC | 1 |
| Matthews, PM | 1 |
| Marchington, DR | 1 |
| Squier, M | 1 |
| Land, J | 1 |
| Brown, RM | 1 |
| Brown, GK | 1 |
| Widdowson, PS | 3 |
| Gyte, A | 3 |
| Simpson, MG | 1 |
| Farnworth, M | 1 |
| Dunn, D | 1 |
| Moore, RB | 1 |
| Wyatt, I | 3 |
| Lock, EA | 1 |
| Tracey, I | 1 |
| Dunn, JF | 1 |
| Parkes, HG | 1 |
| Radda, GK | 1 |
| Upton, R | 2 |
| Foster, J | 1 |
| Coutts, CT | 1 |
| Wald, LL | 1 |
| Nelson, SJ | 1 |
| Day, MR | 1 |
| Noworolski, SE | 1 |
| Henry, RG | 1 |
| Huhn, SL | 1 |
| Chang, S | 1 |
| Prados, MD | 1 |
| Sneed, PK | 1 |
| Larson, DA | 1 |
| Wara, WM | 1 |
| McDermott, M | 1 |
| Dillon, WP | 1 |
| Gutin, PH | 1 |
| Vigneron, DB | 1 |
| Kinoshita, K | 1 |
| Tada, E | 1 |
| Matsumoto, K | 1 |
| Asari, S | 1 |
| Ohmoto, T | 1 |
| Itoh, T | 1 |
| Smith, JC | 1 |
| Pitts, M | 1 |
| Moores, R | 1 |
| Stoffel, M | 2 |
| Eriskat, J | 2 |
| Plesnila, M | 1 |
| Aggarwal, N | 1 |
| Baethmann, A | 2 |
| Edelstein, CL | 1 |
| Shi, Y | 1 |
| Schrier, RW | 1 |
| Chong, VF | 2 |
| Rumpel, H | 2 |
| Aw, YS | 1 |
| Ho, GL | 1 |
| Fan, YF | 2 |
| Chua, EJ | 1 |
| Assy, N | 1 |
| Minuk, GY | 1 |
| Masoero, E | 1 |
| Frattini, P | 1 |
| Favalli, L | 1 |
| Rozza, A | 1 |
| Scelsi, R | 1 |
| Govoni, S | 1 |
| Mukherji, SK | 1 |
| Son, BC | 1 |
| Kim, MC | 1 |
| Choi, BG | 1 |
| Kim, EN | 1 |
| Baik, HM | 1 |
| Choe, BY | 1 |
| Naruse, S | 1 |
| Kang, JK | 1 |
| Igarashi, H | 1 |
| Kwee, IL | 1 |
| Nakada, T | 1 |
| Katayama, Y | 1 |
| Terashi, A | 1 |
| Plesnila, N | 1 |
| Fürst, M | 1 |
| Slezák, J | 3 |
| Tribulová, N | 3 |
| Bernsen, HJ | 1 |
| Heerschap, A | 1 |
| van der Kogel, AJ | 1 |
| van Vaals, JJ | 1 |
| Prick, MJ | 1 |
| Poels, EF | 1 |
| Meyer, J | 1 |
| Grotenhuis, JA | 1 |
| Singh, J | 1 |
| Garg, KN | 1 |
| Mehrotra, GC | 1 |
| Olney, JW | 2 |
| Zorumski, C | 1 |
| Price, MT | 2 |
| Labruyere, J | 2 |
| Rockhold, RW | 1 |
| Acuff, CG | 1 |
| Clower, BR | 1 |
| Samson, L | 1 |
| Christie, MJ | 1 |
| James, LB | 1 |
| Beart, PM | 1 |
| Wieloch, T | 1 |
| Garthwaite, G | 1 |
| Garthwaite, J | 1 |
| Ebel, H | 1 |
| Classen, HG | 1 |
| Späth, M | 1 |
| Iskushev, VS | 1 |
| Lifshits, RI | 1 |
| Slobodin, VB | 1 |
| Laborit, H | 1 |
| Shepherd, JA | 1 |
| Brummel, MC | 1 |
| Murray, LM | 1 |
| Samofalova, MS | 1 |
| Vasků, J | 2 |
| Urbánek, E | 2 |
| Churý, Z | 1 |
| Praslicka, M | 1 |
| Dolezel, S | 1 |
| Bednarík, B | 1 |
| Nevrtal, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Combination of 11C-MET PET and MRS in the Diagnosis of Glioma.[NCT03009318] | 100 participants (Actual) | Interventional | 2012-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for aspartic acid and Necrosis
| Article | Year |
|---|---|
Brain magnetic resonance spectroscopy to differentiate recurrent neoplasm from radiation necrosis: A systematic review and meta-analysis.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Child; Child, Preschool; Choline; Cr | 2023 |
Differentiating Radiation-Induced Necrosis from Recurrent Brain Tumor Using MR Perfusion and Spectroscopy: A Meta-Analysis.
Topics: Aspartic Acid; Blood Volume; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Hum | 2016 |
Proton magnetic resonance spectroscopy imaging in the study of human brain cancer.
Topics: Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Choline; Creatinine; Glioblastoma; Humans; In | 2009 |
Mechanisms of brain injury after global cerebral ischemia.
Topics: Apoptosis; Aspartic Acid; Body Temperature; Brain; Brain Ischemia; Calcium Channels; Cytokines; Dopa | 2006 |
[Effect of excitatory amino acids, Ca2+ on delayed neuronal death in hippocampus following transient forebrain ischemia].
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Calcium-Transporting ATPases; Glutamates; Glutamic Aci | 1993 |
Image-guided 1H NMR spectroscopical and histological characterization of a human brain tumor model in the nude rat; a new approach to monitor changes in tumor metabolism.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Energy Metabolism; Glioblastoma; Humans; Lactates; | 1992 |
52 other studies available for aspartic acid and Necrosis
| Article | Year |
|---|---|
Radiation Necrosis Following Stereotactic Radiosurgery for Trigeminal Neuralgia.
Topics: Aged, 80 and over; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Creatine; Diagnostic Err | 2020 |
Differential effects of caspase inhibitors on TNF-induced necroptosis.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Aspartic Acid; Caspase 3; Caspase 8; Caspase Inhibitors; | 2013 |
Malate-aspartate shuttle inhibitor aminooxyacetic acid leads to decreased intracellular ATP levels and altered cell cycle of C6 glioma cells by inhibiting glycolysis.
Topics: Adenosine Triphosphate; Aminooxyacetic Acid; Animals; Antineoplastic Agents; Apoptosis; Aspartic Aci | 2016 |
[Usefulness of quantitative H-MR spectroscopy for the differentiation between radiation necrosis and recurrence of anaplastic oligodendroglioma].
Topics: Adult; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; F | 2011 |
Reversible parainfectious bilateral "striatal necrosis".
Topics: Aspartic Acid; Child, Preschool; Corpus Striatum; Encephalomyelitis; Female; Functional Laterality; | 2012 |
[STUDIES ON ASPARTIC ACID SALTS. II. BASIC STUDIES].
Topics: Ammonia; Aspartic Acid; Biomedical Research; Carbon Tetrachloride Poisoning; Chemical and Drug Induc | 1964 |
Metabolite and diffusion changes in the rat brain after Leksell Gamma Knife irradiation.
Topics: Analysis of Variance; Animals; Aspartic Acid; Choline; Creatine; Hippocampus; Lactic Acid; Magnetic | 2004 |
Sclerosing effect of OC-108, a novel agent for hemorrhoids, is associated with granulomatous inflammation induced by aluminum.
Topics: Aluminum; Animals; Aspartic Acid; Capillary Permeability; Granuloma; Hemorrhoids; Inflammation; Inje | 2005 |
Ionotropic glutamate receptors and glutamate transporters are involved in necrotic neuronal cell death induced by oxygen-glucose deprivation of hippocampal slice cultures.
Topics: Amino Acid Transport System X-AG; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Ce | 2005 |
Apoptosis, necrosis and cell proliferation-inhibition by cyclosporine A in U937 cells (a human monocytic cell line).
Topics: Apoptosis; Aspartic Acid; Caspase 3; Caspase Inhibitors; Caspases; Cell Proliferation; Cell Survival | 2006 |
Valproic acid prevents brain injury in a canine model of hypothermic circulatory arrest: a promising new approach to neuroprotection during cardiac surgery.
Topics: Animals; Apoptosis; Aspartic Acid; Behavior, Animal; Biomarkers; Brain; Brain Chemistry; Brain Damag | 2006 |
Toll-like receptor 4 Asp299Gly polymorphism is associated with an increased risk of pancreatic necrotic infection in acute pancreatitis: a study in the Chinese population.
Topics: Adult; Amino Acid Substitution; APACHE; Aspartic Acid; Bacterial Infections; China; Female; Gene Fre | 2007 |
Poststreptococcal dystonia with bilateral striatal enlargement: MR imaging and spectroscopic findings.
Topics: Aspartic Acid; Autoantibodies; Bacterial Proteins; Caudate Nucleus; Child; Deoxyribonucleases; Diffu | 2008 |
Effects of L-asparagine and related compounds on the hepatic fatty infiltration and necrosis induced by ethionine and carbon tetrachloride.
Topics: Animals; Asparagine; Aspartic Acid; Carbon Tetrachloride; Chromatography, Gas; Ethionine; Fatty Acid | 1967 |
Correlation of aspartate dose, plasma dicarboxylic amino acid concentration, and neuronal necrosis in infant mice.
Topics: Amino Acids, Dicarboxylic; Animals; Animals, Newborn; Aspartic Acid; Dose-Response Relationship, Dru | 1983 |
[Neutralization of ammonia in cardiac muscle].
Topics: Alanine; Ammonia; Animals; Aspartic Acid; Cardiomyopathies; Glutamates; Glutamine; Isoproterenol; Ma | 1980 |
Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma.
Topics: Adult; Aspartic Acid; Brain Neoplasms; Breast Neoplasms; Carcinoma; Choline; Contrast Media; Creatin | 1994 |
Molecular genetic characterization of an X-linked form of Leigh's syndrome.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Brain Stem; Cells, Cultured; Cesarean Section; Ci | 1993 |
Possible role of nitric oxide in the development of L-2-chloropropionic acid-induced cerebellar granule cell necrosis.
Topics: Animals; Aspartic Acid; Cerebellum; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hydrocarbons, | 1996 |
An in vivo and in vitro H-magnetic resonance spectroscopy study of mdx mouse brain: abnormal development or neural necrosis?
Topics: Animals; Aspartic Acid; Astrocytes; Brain; Brain Chemistry; Choline; Creatine; Dystrophin; Female; G | 1996 |
Calpain activation and not oxidative damage mediates L-2-chloropropionic acid-induced cerebellar granule cell necrosis.
Topics: Administration, Oral; Animals; Antioxidants; Ascorbic Acid; Aspartic Acid; Blotting, Western; Calpai | 1997 |
Serial proton magnetic resonance spectroscopy imaging of glioblastoma multiforme after brachytherapy.
Topics: Aspartic Acid; Brachytherapy; Brain; Brain Neoplasms; Choline; Contrast Media; Creatine; Disease Pro | 1997 |
Proton MR spectroscopy of delayed cerebral radiation in monkeys and humans after brachytherapy.
Topics: Adult; Animals; Aspartic Acid; Brachytherapy; Brain; Brain Neoplasms; Choline; Cranial Irradiation; | 1997 |
L-2-chloropropionic acid-induced cerebellar granule cell necrosis is potentiated by L-type calcium channel antagonists.
Topics: Animals; Aspartic Acid; Body Weight; Calcium Channel Blockers; Cerebellar Diseases; Cerebellum; Drug | 1997 |
The penumbra zone of a traumatic cortical lesion: a microdialysis study of excitatory amino acid release.
Topics: Animals; Aspartic Acid; Brain Injuries; Excitatory Amino Acids; Glutamic Acid; Male; Microdialysis; | 1997 |
Role of caspases in hypoxia-induced necrosis of rat renal proximal tubules.
Topics: Animals; Aspartic Acid; Calpain; Caspase 1; Caspase Inhibitors; Caspases; Coumarins; Cysteine Protei | 1999 |
Temporal lobe necrosis following radiation therapy for nasopharyngeal carcinoma: 1H MR spectroscopic findings.
Topics: Adult; Aspartic Acid; Biomarkers; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy | 1999 |
Serum aspartate but not alanine aminotransferase levels help to predict the histological features of chronic hepatitis C viral infections in adults.
Topics: Adult; Alanine Transaminase; Aspartic Acid; Female; Fibrosis; Forecasting; Hepatitis C, Chronic; Hum | 2000 |
Effect of acute alcohol on ischemia-induced glutamate release and brain damage.
Topics: Animals; Aspartic Acid; Brain; Brain Diseases; Brain Ischemia; Ethanol; Frontal Lobe; Glutamic Acid; | 2000 |
Temporal lobe changes following radiation therapy: imaging and proton MR spectroscopic findings.
Topics: Adult; Aspartic Acid; Carcinoma; Chlorine; Creatinine; Diagnosis, Differential; Female; Humans; Magn | 2001 |
Proton magnetic resonance chemical shift imaging (1H CSI)-directed stereotactic biopsy.
Topics: Adult; Aspartic Acid; Biopsy, Needle; Brain; Brain Neoplasms; Creatine; Diagnosis, Differential; Ene | 2001 |
1H magnetic resonance spectroscopic imaging of permanent focal cerebral ischemia in rat: longitudinal metabolic changes in ischemic core and rim.
Topics: Animals; Aspartic Acid; Biomarkers; Brain Ischemia; Caudate Nucleus; Circle of Willis; Energy Metabo | 2001 |
Release of excitatory amino acids in the penumbra of a focal cortical necrosis.
Topics: Alanine; Animals; Aspartic Acid; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; Glycine; Ma | 2002 |
[Quantitative evaluation of histochemical examinations of the protective effect of KMg-aspartate upon necroses of the myocardium experimentally induced by isoproterenol (author's transl)].
Topics: Animals; Aspartic Acid; Cardiomyopathies; Disease Models, Animal; Dogs; Isoproterenol; Magnesium; Ne | 1976 |
Morphological changes after simultaneous administration of isoproterenol (ISO) and K+,MG2+-Aspartate (KMg-ASP) as a physiological Ca2+ antagonist.
Topics: Animals; Aspartic Acid; Calcium; Dogs; Extracellular Space; Glycogen; Histocytochemistry; Isoprotere | 1975 |
[Influencing myocardial necroses induced by isoproterenol, the physiologic antagonist of calcium, in experiments (author's transl)].
Topics: Animals; Aspartic Acid; Calcium; Dogs; Isoproterenol; Male; Myocardial Infarction; Myocardium; Necro | 1975 |
Effect of aspartate and glutamate on carbon tetrachloride induced liver damage in rats.
Topics: Animals; Aspartic Acid; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Glutamates; Li | 1990 |
L-cysteine, a bicarbonate-sensitive endogenous excitotoxin.
Topics: Animals; Animals, Newborn; Anticonvulsants; Aspartic Acid; Bicarbonates; Caudate Nucleus; Chick Embr | 1990 |
Excitotoxin-induced myocardial necrosis.
Topics: Animals; Aspartic Acid; Blood Pressure; Cardiomyopathies; Heart Rate; Hypothalamus, Middle; Injectio | 1989 |
Calcium influx accompanies but does not cause excitotoxin-induced neuronal necrosis in retina.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Aspartic Acid; Calcium; Glutamates; Glutamic Acid; In Vitr | 1985 |
An excitatory amino acid projection from rat prefrontal cortex to periaqueductal gray.
Topics: Animals; Aspartic Acid; Frontal Lobe; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Necrosis; | 1986 |
Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Caudate Nucleus; Electroencephalog | 1985 |
Neurotoxicity of excitatory amino acid receptor agonists in rat cerebellar slices: dependence on calcium concentration.
Topics: Animals; Aspartic Acid; Calcium; Cerebellum; Golgi Apparatus; Granulocytes; Kainic Acid; N-Methylasp | 1986 |
Aspartate-induced neuronal necrosis in infant mice: protective effect of carbohydrate and insulin.
Topics: Animals; Aspartic Acid; Glucose; Glutamates; Hypothalamus; Insulin; Mice; Necrosis; Neurons; Starch | 1988 |
Correlation of glutamate plus aspartate dose, plasma amino acid concentration and neuronal necrosis in infant mice.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Aspartic Acid; Dose-Response Relationship, Drug; Glutamate | 1985 |
Proceedings: Extracellular hypochloremic alkalosis, cardiotoxicity of epinephrine and protective effects of magnesium compounds.
Topics: Alkalosis; Animals; Aspartic Acid; Chlorides; Epinephrine; Fludrocortisone; Heart; Hypercalcemia; Ma | 1974 |
[The effect of L-aspartic acid in isoproterenol necrosis of cardiac muscle].
Topics: Alanine Transaminase; Amino Acids; Animals; Aspartate Aminotransferases; Aspartic Acid; Heart Diseas | 1972 |
[Physiopathology and pharmacology of myocardial necrosis].
Topics: Animals; Aspartic Acid; Dihydroxyphenylalanine; Glucose; Heart; Humans; Insulin; Lysosomes; Monoamin | 1974 |
Toxicity of protein hydrolysate solutions: correlation of glutamate dose and neuronal necrosis to plasma amino acid levels in young mice.
Topics: Age Factors; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Caseins; Dose-Response Relations | 1974 |
[Levels of free amino acids in the blood and heart muscle in the human at various periods of myocardial infarct (clinical anatomical parallels)].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Erythrocytes; Glutamates; Glycine; Hi | 1968 |
The nonspecific changes in the heart muscle after various cardiotoxic interventions and their efficient experimental prevention.
Topics: Adrenal Cortex Hormones; Animals; Aspartic Acid; Chlorides; Diphtheria Toxin; Electrolytes; Female; | 1969 |
The influence of K-Mg-aspartate upon the incidence and development of non-specific cardiac necroses in the young albino rat.
Topics: Animals; Aspartic Acid; Heart Diseases; Magnesium; Necrosis; Potassium; Rats | 1966 |