aspartic acid has been researched along with Muscular Dystrophies in 13 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Muscular Dystrophies: A heterogeneous group of inherited MYOPATHIES, characterized by wasting and weakness of the SKELETAL MUSCLE. They are categorized by the sites of MUSCLE WEAKNESS; AGE OF ONSET; and INHERITANCE PATTERNS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Brain magnetic resonance spectroscopy (MRS) and diffusion tensor imaging (DTI) in one patient with merosin-deficient congenital muscular dystrophy (MDCMD) revealed significant metabolite (choline, creatine, N-acetyl aspartate) level reductions, fractional anisotropy (FA) reduction and increased apparent diffusion coefficient (ADC) in the white matter (p<0." | 3.74 | MR spectroscopy and diffusion tensor imaging of the brain in congenital muscular dystrophy with merosin deficiency: metabolite level decreases, fractional anisotropy decreases, and apparent diffusion coefficient increases in the white matter. ( Fock, JM; Irwan, R; Meiners, LC; Oudkerk, M; Potze, JH; Sijens, PE, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (53.85) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sijens, PE | 1 |
| Fock, JM | 1 |
| Meiners, LC | 1 |
| Potze, JH | 1 |
| Irwan, R | 1 |
| Oudkerk, M | 1 |
| Brockmann, K | 1 |
| Dechent, P | 1 |
| Bönnemann, C | 1 |
| Schreiber, G | 1 |
| Frahm, J | 1 |
| Hanefeld, F | 1 |
| MacLeod, H | 1 |
| Pytel, P | 1 |
| Wollmann, R | 1 |
| Chelmicka-Schorr, E | 1 |
| Silver, K | 1 |
| Anderson, RB | 1 |
| Waggoner, D | 1 |
| McNally, EM | 1 |
| Matta, AP | 1 |
| Gonsalves, Mde C | 1 |
| Bizzi, A | 1 |
| Castelli, G | 1 |
| Bugiani, M | 1 |
| Barker, PB | 1 |
| Herskovits, EH | 1 |
| Danesi, U | 1 |
| Erbetta, A | 1 |
| Moroni, I | 1 |
| Farina, L | 1 |
| Uziel, G | 1 |
| Berlinguet, L | 1 |
| Srivastava, U | 1 |
| Rae, C | 1 |
| Scott, RB | 1 |
| Thompson, CH | 1 |
| Dixon, RM | 1 |
| Dumughn, I | 1 |
| Kemp, GJ | 1 |
| Male, A | 1 |
| Pike, M | 1 |
| Styles, P | 1 |
| Radda, GK | 1 |
| Bajusz, E | 1 |
| Homburger, F | 1 |
| Baker, JR | 1 |
| Bogdonoff, P | 1 |
| Kleine, TO | 1 |
| Chlond, H | 1 |
| Gusev, EI | 1 |
| Nakahara, M | 1 |
| Yamada, S | 1 |
| Radu, H | 1 |
| Kapusi, A | 1 |
| Stenzel, K | 1 |
| Maskaleris, ML | 1 |
| Gross, S | 1 |
| Milhorat, AT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A LAMA2-related Muscular Dystrophy Study: Brain Magnetic Resonance Imaging (MRI)and Brain Electrophysiology Evaluation[NCT01952028] | 0 participants (Actual) | Observational | 2013-11-30 | Withdrawn | |||
| Genetic Studies of Patients and Their Families With Inherited Cardiovascular and Neuromuscular Diseases.[NCT00138931] | 2,000 participants (Anticipated) | Observational | 1996-09-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 other studies available for aspartic acid and Muscular Dystrophies
| Article | Year |
|---|---|
MR spectroscopy and diffusion tensor imaging of the brain in congenital muscular dystrophy with merosin deficiency: metabolite level decreases, fractional anisotropy decreases, and apparent diffusion coefficient increases in the white matter.
Topics: Anisotropy; Aspartic Acid; Brain; Brain Chemistry; Child; Choline; Diffusion Magnetic Resonance Imag | 2007 |
Quantitative proton MRS of cerebral metabolites in laminin alpha2 chain deficiency.
Topics: Adolescent; Aspartic Acid; Cerebral Cortex; Child; Child, Preschool; Creatine; Dipeptides; Humans; I | 2007 |
A novel FKRP mutation in congenital muscular dystrophy disrupts the dystrophin glycoprotein complex.
Topics: Asparagine; Aspartic Acid; Child, Preschool; Dystrophin; Female; Glycoproteins; Humans; Muscular Dys | 2007 |
Merosin-positive congenital muscular dystrophy: neuroimaging findings.
Topics: Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Infant; Laminin; Magnetic Resonance Imaging | 2007 |
Classification of childhood white matter disorders using proton MR spectroscopic imaging.
Topics: Adrenoleukodystrophy; Adult; Alexander Disease; Aspartic Acid; Brain; Child; Child, Preschool; Choli | 2008 |
Effect of various amino acids on the incorporation of 14C-L-leucine in the tissue proteins of normal and dystrophic mice.
Topics: Amino Acids; Animals; Antineoplastic Agents; Aspartic Acid; Brain; Carbon Isotopes; Cycloparaffins; | 1967 |
Brain biochemistry in Duchenne muscular dystrophy: a 1H magnetic resonance and neuropsychological study.
Topics: Age Factors; Aspartic Acid; Brain; Cerebellum; Child; Choline; Cognition; Creatine; Humans; Magnetic | 1998 |
Dissociation of factors influencing myocardial degeneration and generalized cardiocirculatory failure.
Topics: Animals; Aspartic Acid; Cricetinae; Diet; Digitoxin; Disease Models, Animal; Edema; Epinephrine; Fem | 1969 |
[On the enzymatic differential diagnosis of the involvement of various organs in Erb's progressive muscular dystrophy during three medications].
Topics: Adolescent; Aspartic Acid; Brain; Child; Child, Preschool; Clinical Enzyme Tests; Diagnosis, Differe | 1969 |
[Hyperaminoaciduria in children suffering from progressive muscular dystrophy].
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Aspartic Acid; Child; Child, Pr | 1967 |
Studies on progressive muscular dystrophy. IV. Effects of original amino acids mixture on progressive muscular dystrophy.
Topics: Adenosine Triphosphate; Adolescent; Adult; Amino Acids; Arginine; Asparagine; Aspartic Acid; Blood P | 1967 |
Defect of coenzyme-A activity in progessive muscular dystrophy.
Topics: Aspartic Acid; Child; Child, Preschool; Citric Acid Cycle; Coenzyme A; Extracellular Space; Glutamat | 1968 |
Urinary amino acid and peptide excretion patterns in patients with muscular dystrophy (Duchenne). A preliminary study with the autoanalyzer.
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Autoanalysis; Child; Child | 1969 |