aspartic acid has been researched along with Muscle Spasticity in 9 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In these patients spasticity began in the legs and progressed slowly and steadily." | 1.32 | Primary lateral sclerosis: A heterogeneous disorder composed of different subtypes? ( Butman, JA; Floeter, MK; Pagan, F; Statland, J; Zhai, P, 2003) |
| "A slowly progressive sensory ataxia and tremor manifested at the age of 3 to 16 years and distal spasticity in adolescence." | 1.32 | Five new cases of a recently described leukoencephalopathy with high brain lactate. ( Aärimaa, T; Autti, T; Häkkinen, AM; Koillinen, H; Kuusi, T; Linnankivi, T; Lönnqvist, T; Lundbom, N; Pihko, H; Sainio, K; Valanne, L, 2004) |
| "Quisqualate induces myoclonic seizures in mice after intracerebroventricular application and increases muscle tone in genetically spastic rats following intrathecal injection." | 1.27 | Unusual interactions of excitatory amino acid receptor agonists: alpha- and beta-kainate antagonize motor responses to N-methyl-D-aspartate in rodents. ( Klockgether, T; Meldrum, BS; Schwarz, M; Sontag, KH; Turski, L, 1987) |
| "Some of the clinical signs of spasticity improved in the animals injected with glycine compared to the saline-injected controls." | 1.26 | Effects of glycine administration on canine experimental spinal spasticity and the levels of glycine, glutamate, and aspartate in the lumbar spinal cord. ( Campbell, RL; Galvin, MR; Hall, PV; Jones, AR; Smith, JE, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhai, P | 1 |
| Pagan, F | 1 |
| Statland, J | 1 |
| Butman, JA | 1 |
| Floeter, MK | 1 |
| Linnankivi, T | 1 |
| Lundbom, N | 1 |
| Autti, T | 1 |
| Häkkinen, AM | 1 |
| Koillinen, H | 1 |
| Kuusi, T | 1 |
| Lönnqvist, T | 1 |
| Sainio, K | 1 |
| Valanne, L | 1 |
| Aärimaa, T | 1 |
| Pihko, H | 1 |
| Jurkiewicz, E | 1 |
| Mierzewska, H | 1 |
| Bekiesińska-Figatowska, M | 1 |
| Pakua-Kościesza, I | 1 |
| Kmieć, T | 1 |
| Scheper, G | 1 |
| van der Knaap, MS | 1 |
| Pronicka, E | 1 |
| Mertens, P | 1 |
| Ghaemmaghami, C | 1 |
| Bert, L | 1 |
| Perret-Liaudet, A | 1 |
| Sindou, M | 1 |
| Renaud, B | 1 |
| Espay, AJ | 1 |
| Bodensteiner, JB | 1 |
| Patel, H | 1 |
| Hall, PV | 2 |
| Smith, JE | 2 |
| Campbell, RL | 2 |
| Felten, DL | 1 |
| Aprison, MH | 1 |
| Galvin, MR | 1 |
| Jones, AR | 1 |
| Turski, L | 2 |
| Schwarz, M | 2 |
| Turski, WA | 1 |
| Klockgether, T | 2 |
| Sontag, KH | 2 |
| Collins, JF | 1 |
| Meldrum, BS | 1 |
9 other studies available for aspartic acid and Muscle Spasticity
| Article | Year |
|---|---|
Primary lateral sclerosis: A heterogeneous disorder composed of different subtypes?
Topics: Adult; Aspartic Acid; Atrophy; Brain Stem; Choline; Creatinine; Disease Progression; Evoked Potentia | 2003 |
Five new cases of a recently described leukoencephalopathy with high brain lactate.
Topics: Adolescent; Aspartic Acid; Ataxia; Brain Chemistry; Brain Diseases, Metabolic; Brain Stem; Central N | 2004 |
MRI of a family with leukoencephalypathy with vanishing white matter.
Topics: Adolescent; Amino Acid Substitution; Aspartic Acid; Brain; Case-Control Studies; Cerebellar Ataxia; | 2005 |
Amino acids in spinal dorsal horn of patients during surgery for neuropathic pain or spasticity.
Topics: Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Extracellular Space; Feasibility S | 2000 |
Episodic coma in a new leukodystrophy.
Topics: Aspartic Acid; Ataxia; Brain; Child; Choline; Coma; Creatine; Demyelinating Diseases; Epilepsy, Post | 2002 |
Neurochemical correlates of spasticity.
Topics: Animals; Aspartic Acid; Dogs; Female; gamma-Aminobutyric Acid; Glutamates; Glycine; Muscle Spasticit | 1976 |
Effects of glycine administration on canine experimental spinal spasticity and the levels of glycine, glutamate, and aspartate in the lumbar spinal cord.
Topics: Animals; Aspartic Acid; Dogs; Female; Glutamates; Glycine; Muscle Hypotonia; Muscle Spasticity; Spin | 1979 |
Muscle relaxant action of excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Female; Glutamates; Kynurenic Acid | 1985 |
Unusual interactions of excitatory amino acid receptor agonists: alpha- and beta-kainate antagonize motor responses to N-methyl-D-aspartate in rodents.
Topics: Animals; Aspartic Acid; Electromyography; Kainic Acid; Male; Mice; Motor Activity; Muscle Spasticity | 1987 |