Page last updated: 2024-11-08

aspartic acid and Muscle Contraction

aspartic acid has been researched along with Muscle Contraction in 44 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"To investigate the role of glutamic (Glu) and aspartic acid (Asp) in migraine, we measured the plasma amino acids in migraine patients with and without aura, between and during attacks, and compared the profiles with the plasma amino acid profiles of tension headache patients and healthy controls."3.68Neuroexcitatory plasma amino acids are elevated in migraine. ( Bos, KD; Bruyn, GW; Ferrari, MD; Malessy, MJ; Odink, J, 1990)
"Both octopamine and proctolin potentiate nerve-evoked skeletal muscle contractions in the horseshoe crab, Limulus."3.67Neuromuscular modulation in Limulus by both octopamine and proctolin. ( Gerlach, PH; Rane, SG; Wyse, GA, 1984)
"Tizanidine (TIZ) has long been known to be an alpha 2-adrenoceptor agonist and inhibitor of ASP and GLU release."1.28Effects of tizanidine on morphine physical dependence: attenuation and intensification. ( Ariciŏglu, F; Dizdar, Y; Esin, Y; Koyuncuŏglu, H; Uresin, Y, 1992)
"Glycine, which plays an inhibitory role, especially in the spinal cord, reacted with 6 per cent decrease, whereas GABA which is also considered as an inhibitory neurotransmitter showed a change of + 11 per cent on the potentiated side as compared to the unpotentiated side."1.25Neurochemical aspects of post-tetanic potentiation of monosynaptic reflexes in the cat spinal cord. I. Analysis of amino acids at maximum of potentiation. ( Behbehani, AW; Neuhoff, V; Quentin, CD, 1975)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199025 (56.82)18.7374
1990's9 (20.45)18.2507
2000's4 (9.09)29.6817
2010's5 (11.36)24.3611
2020's1 (2.27)2.80

Authors

AuthorsStudies
Farney, TM1
MacLellan, MJ1
Hearon, CM1
Johannsen, NM1
Nelson, AG1
Swindle, N1
Tikunova, SB1
Rysev, NA1
Karpicheva, OE1
Redwood, CS1
Borovikov, YS1
Ahmed, Z1
Wieraszko, A1
Mamidi, R1
Gollapudi, SK1
Mallampalli, SL1
Chandra, M1
Calabrese, AN1
Markulic, K1
Musgrave, IF1
Guo, H1
Zhang, L1
Bowie, JH1
Milovanovic, DR1
Jankovic, SM2
KITA, T1
KAMIYA, H1
KIYOTA, C1
Iyer, D1
Chang, D1
Marx, J1
Wei, L1
Olson, EN1
Parmacek, MS1
Balasubramanyam, A1
Schwartz, RJ1
Surendran, S1
Nakahara, M1
Yoshihara, T1
Tokita, T1
Nakanishi, Y1
Sakahashi, H1
Shibata, N1
Rane, SG2
Gerlach, PH1
Wyse, GA2
Clark, RB1
Gration, KA1
Usherwood, PN1
Karagiannis, K1
Stavropoulos, G1
Poulos, C1
Jordan, CC1
Hagan, RM1
Hull, RA1
Shankley, NP1
Harper, EA1
Gerkowitch, VP1
Black, JW1
Hand, GA1
Kramer, GL1
Petty, F1
Ordway, GA1
Wilson, LB1
Sakube, Y1
Ando, H1
Kagawa, H1
Barron, JT1
Gu, L1
Parrillo, JE1
Milovanović, D1
Matović, M1
Irić-Cupić, V1
Schachter, D1
Sang, JC1
Behbehani, AW1
Quentin, CD1
Neuhoff, V1
Koidl, B1
Florey, E1
Constanti, A1
Nistri, A1
Hall, PV1
Smith, JE1
Lane, JD1
Mote, TR1
Campbell, RL1
Koyuncuŏglu, H1
Ariciŏglu, F1
Uresin, Y1
Dizdar, Y1
Esin, Y1
Ferrari, MD1
Odink, J1
Bos, KD1
Malessy, MJ1
Bruyn, GW1
Aas, P1
Jaspers, SR1
Henriksen, EJ1
Satarug, S1
Tischler, ME1
Shannon, HE1
Sawyer, BD1
Gremion, G2
Pahud, P2
Gobelet, C2
Podgornaia, LA1
Kaplunenko, NA1
Klockgether, T1
Schwarz, M1
Turski, L1
Sontag, KH1
Moroni, F1
Luzzi, S1
Franchi-Micheli, S1
Zilletti, L1
de Haan, A1
van Doorn, JE1
Westra, HG1
Johnson, JL1
Jorgensen, EC1
Kiraly-Olah, IC1
Lee, TC1
Windridge, GC1
Regoli, D1
Rioux, F1
Park, WK1
Choi, C1
Türker, RK1
Gündoğan, NU1
Shinozaki, H1
Shibuya, I1
Atwater, I1
Rojas, E1
Vergara, J1
Buniatian, HC1
Hovhannissian, VS1
Aprikian, GV1
Kerkut, GA1
Shapira, A1
Walker, RJ1

Reviews

1 review available for aspartic acid and Muscle Contraction

ArticleYear
Glutamic acid as a synaptic transmitter in the nervous system. A review.
    Brain research, 1972, Feb-11, Volume: 37, Issue:1

    Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Biological Transport, Active; Central Nervous S

1972

Trials

3 trials available for aspartic acid and Muscle Contraction

ArticleYear
[Arginine aspartate and muscular activity. II].
    Schweizerische Zeitschrift fur Sportmedizin, 1989, Volume: 37, Issue:4

    Topics: Adult; Arginine; Aspartic Acid; Heart Rate; Humans; Lactates; Male; Muscle Contraction; Oxygen Consu

1989
[Arginine aspartate and muscular activity].
    Schweizerische Zeitschrift fur Sportmedizin, 1987, Volume: 35, Issue:1

    Topics: Arginine; Aspartic Acid; Double-Blind Method; Electromyography; Humans; Isometric Contraction; Muscl

1987
Effects of potassium + magnesium aspartate on muscle metabolism and force development during short intensive static exercise.
    International journal of sports medicine, 1985, Volume: 6, Issue:1

    Topics: Adult; Animals; Aspartic Acid; Double-Blind Method; Humans; Male; Muscle Contraction; Muscles; Physi

1985

Other Studies

40 other studies available for aspartic acid and Muscle Contraction

ArticleYear
The Effect of Aspartate and Sodium Bicarbonate Supplementation on Muscle Contractile Properties Among Trained Men.
    Journal of strength and conditioning research, 2020, Volume: 34, Issue:3

    Topics: Ammonia; Aspartic Acid; Dietary Supplements; Exercise; Exercise Test; Humans; Male; Muscle Contracti

2020
Hypertrophic cardiomyopathy-linked mutation D145E drastically alters calcium binding by the C-domain of cardiac troponin C.
    Biochemistry, 2010, Jun-15, Volume: 49, Issue:23

    Topics: Amino Acid Substitution; Aspartic Acid; Calcium; Calcium Signaling; Cardiomyopathy, Hypertrophic; Gl

2010
The effect of the Asp175Asn and Glu180Gly TPM1 mutations on actin-myosin interaction during the ATPase cycle.
    Biochimica et biophysica acta, 2012, Volume: 1824, Issue:2

    Topics: Actins; Actomyosin; Adenosine Triphosphatases; Amino Acid Substitution; Animals; Asparagine; Asparti

2012
Trans-spinal direct current enhances corticospinal output and stimulation-evoked release of glutamate analog, D-2,3-³H-aspartic acid.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:9

    Topics: Animals; Aspartic Acid; Behavior, Animal; Calcium; Cerebral Cortex; Disease Models, Animal; Electric

2012
Alanine or aspartic acid substitutions at serine23/24 of cardiac troponin I decrease thin filament activation, with no effect on crossbridge detachment kinetics.
    Archives of biochemistry and biophysics, 2012, Sep-01, Volume: 525, Issue:1

    Topics: Adenosine Triphosphatases; Alanine; Amino Acid Substitution; Animals; Aspartic Acid; Calcium; Cyclic

2012
Structural and activity changes in three bioactive anuran peptides when Asp is replaced by isoAsp.
    Peptides, 2012, Volume: 38, Issue:2

    Topics: Animals; Anura; Aspartic Acid; Guinea Pigs; Models, Molecular; Muscle Contraction; Muscle, Smooth; P

2012
A pharmacological analysis of the contractile effects of glutamate on rat and human isolated gut smooth muscle strips.
    Methods and findings in experimental and clinical pharmacology, 2002, Volume: 24, Issue:10

    Topics: Aged; Animals; Aspartic Acid; Cycloleucine; Evoked Potentials, Motor; Female; Gastric Fundus; Glutam

2002
THE PHASE REVERSAL PHENOMENON OF THE GABA-ACTION ON THE HIND GUT OF THE CRAYFISH CAUSED BY THE CHANGE IN THE IONIC COMPOSITION OF THE EXTERNAL MEDIUM.
    Biochemical pharmacology, 1965, Volume: 14

    Topics: Acetylcholine; Alanine; Aminobutyrates; Animals; Aspartic Acid; Astacoidea; Bromides; Calcium; Crust

1965
Serum response factor MADS box serine-162 phosphorylation switches proliferation and myogenic gene programs.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Mar-21, Volume: 103, Issue:12

    Topics: Actins; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Cell Differentiation;

2006
Upregulation of N-acetylaspartic acid alters inflammation, transcription and contractile associated protein levels in the stomach and smooth muscle contractility.
    Molecular biology reports, 2009, Volume: 36, Issue:1

    Topics: Analysis of Variance; Animals; Aspartic Acid; Contractile Proteins; Gastric Mucosa; Gene Expression

2009
Difference in action between D- and L-potassium and magnesium aspartates.
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:11

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Aspartic Acid; Electric Stimulation; In Vitro

1966
Neuromuscular modulation in Limulus by both octopamine and proctolin.
    Journal of neurobiology, 1984, Volume: 15, Issue:3

    Topics: Animals; Aspartic Acid; Biogenic Amines; Calcium; Drug Interactions; Evoked Potentials; Glutamates;

1984
Influence of glutamate and aspartate on time course of decay of excitatory synaptic currents at locust neuromuscular junctions.
    Brain research, 1980, Jun-16, Volume: 192, Issue:1

    Topics: Animals; Aspartic Acid; Evoked Potentials; Glutamates; Grasshoppers; Muscle Contraction; Neuromuscul

1980
Synthesis of a potent antagonist of substance P by replacing the CH2SCH3 and the alpha-carboxamide groups of the methionine at [Orn6]-SP6-11 by benzyl ester groups.
    International journal of peptide and protein research, 1993, Volume: 42, Issue:6

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Guinea Pigs; Ileum; Methionine; Molecular Sequence Data

1993
2-Naphthalenesulphonyl L-aspartyl-(2-phenethyl)amide (2-NAP)--a selective cholecystokinin CCKA-receptor antagonist.
    British journal of pharmacology, 1993, Volume: 108, Issue:3

    Topics: Aged; Amylases; Animals; Aspartic Acid; Binding, Competitive; Gallbladder; Guinea Pigs; Humans; Ileu

1993
Excitatory amino acid concentrations in the spinal dorsal horn of cats during muscle contraction.
    Journal of applied physiology (Bethesda, Md. : 1985), 1996, Volume: 81, Issue:1

    Topics: Animals; Aspartic Acid; Blood Pressure; Cats; Chromatography, High Pressure Liquid; Electric Stimula

1996
An abnormal ketamine response in mutants defective in the ryanodine receptor gene ryr-1 (unc-68) of Caenorhabditis elegans.
    Journal of molecular biology, 1997, Apr-11, Volume: 267, Issue:4

    Topics: Amino Acid Sequence; Anesthetics, Dissociative; Animals; Animals, Genetically Modified; Aspartic Aci

1997
Malate-aspartate shuttle, cytoplasmic NADH redox potential, and energetics in vascular smooth muscle.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:8

    Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Biological Transport; Cytoplasm; Energy Metabolism; Glu

1998
The effects of excitatory amino acids on isolated gut segments of the rat.
    Pharmacological research, 1999, Volume: 39, Issue:2

    Topics: Animals; Aspartic Acid; Cycloleucine; Digestive System; Digestive System Physiological Phenomena; Ex

1999
Aortic leucine-to-glutamate pathway: metabolic route and regulation of contractile responses.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:3

    Topics: Animals; Aorta; Aspartic Acid; Carbon Dioxide; Endothelium, Vascular; Glutamic Acid; In Vitro Techni

2002
Neurochemical aspects of post-tetanic potentiation of monosynaptic reflexes in the cat spinal cord. I. Analysis of amino acids at maximum of potentiation.
    Neurobiology, 1975, Volume: 5, Issue:1

    Topics: Action Potentials; Alanine; Amino Acids; Animals; Aspartic Acid; Cats; Electric Stimulation; Female;

1975
Factor I and GABA: resolution of a long-standing problem.
    Comparative biochemistry and physiology. C: Comparative pharmacology, 1975, Jun-01, Volume: 51, Issue:1

    Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Astacoidea; gamma-Aminobutyric Acid; Glutamates

1975
Further observations on the interaction between glutamate and aspartate on lobster muscle.
    British journal of pharmacology, 1979, Volume: 65, Issue:2

    Topics: Animals; Aspartic Acid; Drug Interactions; Evoked Potentials; Glutamates; In Vitro Techniques; Muscl

1979
Changes of content and specific radioactivity of aspartate in spastic feline spinal cord.
    Brain research, 1979, Feb-23, Volume: 162, Issue:2

    Topics: Animals; Aspartic Acid; Cats; Decerebrate State; Female; Hindlimb; Muscle Contraction; Reflex; Spina

1979
Effects of tizanidine on morphine physical dependence: attenuation and intensification.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:4

    Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Aspartic Acid; Behavior, Animal; Clonidine; Glutamat

1992
Neuroexcitatory plasma amino acids are elevated in migraine.
    Neurology, 1990, Volume: 40, Issue:10

    Topics: Adult; Aging; Aspartic Acid; Female; Glutamates; Glutamic Acid; Headache; Humans; Male; Middle Aged;

1990
Prejunctional control of cholinergic nerves in airway smooth muscle exerted by muscarinic, purinergic and glutamergic receptors.
    Progress in brain research, 1990, Volume: 84

    Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aspartic Acid; Bronchi; Diamin

1990
Effects of stretching and disuse on amino acids in muscles of rat hind limbs.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:4

    Topics: Amino Acids; Ammonia; Animals; Aspartic Acid; Denervation; Female; Glutamates; Glutamic Acid; Glutam

1989
Glutamate receptors of the N-methyl-D-aspartate subtype in the myenteric plexus of the guinea pig ileum.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:2

    Topics: Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Guinea

1989
[Effect of hypochloric solutions on the electrophysiologic processes of smooth muscles].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1985, Volume: 71, Issue:12

    Topics: Animals; Aspartic Acid; Chlorides; Colon; Glutamates; Glutamic Acid; Guinea Pigs; In Vitro Technique

1985
The rat ventromedial thalamic nucleus and motor control: role of N-methyl-D-aspartate-mediated excitation, GABAergic inhibition, and muscarinic transmission.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1986, Volume: 6, Issue:6

    Topics: Animals; Aspartic Acid; Electromyography; gamma-Aminobutyric Acid; Locomotion; Male; Movement; Musci

1986
The presence of N-methyl-D-aspartate-type receptors for glutamic acid in the guinea pig myenteric plexus.
    Neuroscience letters, 1986, Jul-11, Volume: 68, Issue:1

    Topics: Animals; Aspartic Acid; Glutamates; Glutamic Acid; Guinea Pigs; Ileum; In Vitro Techniques; Muscle C

1986
Neuromuscular synaptic transmission in Limulus polyphemus--I. Actions of aspartate, glutamate and the natural transmitter.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1987, Volume: 87, Issue:1

    Topics: Animals; Aspartic Acid; Glutamates; Horseshoe Crabs; In Vitro Techniques; Membrane Potentials; Micro

1987
Angiotensin II analogs. 11. Further studies on des-aspartyl-angiotensin II.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:3

    Topics: Amino Acid Sequence; Angiotensin II; Animals; Aspartic Acid; Blood Pressure; Ileum; In Vitro Techniq

1974
Role of the N-terminal amino acid for the biological activities of angiotensin and inhibitory analogues.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:1

    Topics: Amino Acids; Aminopeptidases; Angiotensin II; Animals; Aorta; Aspartic Acid; Blood Pressure; Chromat

1974
A comparative study of two structurally related analogs of Asp1-Ile5-angiotensin II.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:4

    Topics: Adrenal Glands; Adrenalectomy; Aminopeptidases; Angiotensin II; Animals; Aorta; Aspartic Acid; Blood

1974
Potentiation of glutamate-induced depolarization by kainic acid in the crayfish opener muscle.
    Neuropharmacology, 1974, Volume: 13, Issue:10-11

    Topics: Acetates; Animals; Aspartic Acid; Astacoidea; Dose-Response Relationship, Drug; Electric Stimulation

1974
Calcium influxes and tension development in perfused single barnacle muscle fibres under membrane potential control.
    The Journal of physiology, 1974, Volume: 243, Issue:2

    Topics: Acetates; Animals; Aspartic Acid; Buffers; Calcium; Calcium Radioisotopes; Culture Media; Electric S

1974
The participation of N-acetyl-L-aspartic acid in brain metabolism.
    Journal of neurochemistry, 1965, Volume: 12, Issue:8

    Topics: Acetylcholine; Aminobutyrates; Amobarbital; Animals; Aspartic Acid; Brain; Caffeine; Glucose; In Vit

1965
The effect of acetylcholine, glutamic acid and GABA on the contractions of the perfused cockroach leg.
    Comparative biochemistry and physiology, 1965, Volume: 16, Issue:1

    Topics: Acetylcholine; Aminobutyrates; Animals; Aspartic Acid; Glutamates; In Vitro Techniques; Insecta; Mus

1965