Page last updated: 2024-11-08

aspartic acid and Morphine Dependence

aspartic acid has been researched along with Morphine Dependence in 9 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Morphine Dependence: Strong dependence, both physiological and emotional, upon morphine.

Research Excerpts

ExcerptRelevanceReference
"A body of evidence supports that excitatory amino acid systems, particularly glutamatergic one, participate in morphine dependence and naloxone-precipitated withdrawal."8.81[Involvement of glial glutamate transporters in morphine dependence and naloxone-precipitated withdrawal]. ( Nakagawa, T, 2001)
"A body of evidence supports that excitatory amino acid systems, particularly glutamatergic one, participate in morphine dependence and naloxone-precipitated withdrawal."4.81[Involvement of glial glutamate transporters in morphine dependence and naloxone-precipitated withdrawal]. ( Nakagawa, T, 2001)
"Tizanidine (TIZ) has long been known to be an alpha 2-adrenoceptor agonist and inhibitor of ASP and GLU release."1.28Effects of tizanidine on morphine physical dependence: attenuation and intensification. ( Ariciŏglu, F; Dizdar, Y; Esin, Y; Koyuncuŏglu, H; Uresin, Y, 1992)
"When nalorphine (20mg/kg) was administered to rats previously treated with morphine three times daily for 2 weeks, there was an increase in brain glucose (100%), lactate (23%), pyruvate (18%) and citrate (10%) concentrations."1.25The effects of acute and chronic morphine treatment and of morphine withdrawal on rat brain in vivo. ( Harris, RL; Hawkins, RA; Miller, AL; Veech, RL, 1972)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's2 (22.22)18.2507
2000's2 (22.22)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cloak, CC1
Chang, L1
O'Neil, SP1
Ernst, TM1
Anderson, DC1
Donahoe, RM1
Wen, ZH1
Wu, GJ1
Chang, YC1
Wang, JJ1
Wong, CS1
Smith, JE1
Co, C1
Freeman, ME1
Sands, MP1
Lane, JD1
Nakagawa, T1
Koyuncuoğlu, H4
Genc, E2
Güngör, M3
Eroğlu, L2
Sağduyu, H3
Ariciŏglu, F2
Uresin, Y1
Dizdar, Y1
Esin, Y1
Miller, AL1
Hawkins, RA1
Harris, RL1
Veech, RL1

Reviews

1 review available for aspartic acid and Morphine Dependence

ArticleYear
[Involvement of glial glutamate transporters in morphine dependence and naloxone-precipitated withdrawal].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2001, Volume: 121, Issue:9

    Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Brain; Cells, Cultured; Excita

2001

Other Studies

8 other studies available for aspartic acid and Morphine Dependence

ArticleYear
Neurometabolite abnormalities in simian immunodeficiency virus-infected macaques with chronic morphine administration.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2011, Volume: 6, Issue:3

    Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Creatine; Glutamic Acid; Inositol; Macaca; Magnetic

2011
Dexamethasone modulates the development of morphine tolerance and expression of glutamate transporters in rats.
    Neuroscience, 2005, Volume: 133, Issue:3

    Topics: Amino Acid Transport System X-AG; Analgesics, Opioid; Animals; Aspartic Acid; Dexamethasone; Drug To

2005
Neurotransmitter turnover in rat striatum is correlated with morphine self-administration.
    Nature, 1980, Sep-11, Volume: 287, Issue:5778

    Topics: Animals; Aspartic Acid; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glycine; Hum

1980
The antagonizing effect of aspartic acid on the brain levels of monoamines and free amino acids during the development of tolerance to the physical dependence on morphine.
    Psychopharmacology, 1977, Oct-20, Volume: 54, Issue:2

    Topics: Amines; Amino Acids; Animals; Aspartic Acid; Brain; Cats; Drug Tolerance; Humans; Morphine; Morphine

1977
Antagonizing effect of aspartic acid on the development of physical dependence on and tolerance to morphine in the rat.
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:9

    Topics: Amino Acids; Animals; Aspartic Acid; Body Weight; Brain; Drug Tolerance; Humans; Morphine; Morphine

1977
Effects of tizanidine on morphine physical dependence: attenuation and intensification.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:4

    Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Aspartic Acid; Behavior, Animal; Clonidine; Glutamat

1992
Intensification and attenuation of morphine dependence by D-aspartic acid and PLG.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:1

    Topics: Animals; Asparaginase; Aspartic Acid; Brain; Mice; Mice, Inbred BALB C; Morphine Dependence; MSH Rel

1990
The effects of acute and chronic morphine treatment and of morphine withdrawal on rat brain in vivo.
    The Biochemical journal, 1972, Volume: 129, Issue:2

    Topics: Acetazolamide; Adenosine Diphosphate; Adenosine Triphosphate; Ammonia; Animals; Arteries; Aspartic A

1972