aspartic acid has been researched along with Metastase in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (32.35) | 18.7374 |
| 1990's | 4 (11.76) | 18.2507 |
| 2000's | 12 (35.29) | 29.6817 |
| 2010's | 6 (17.65) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, CX; Duan, CF; Liu, XJ; Su, HW; Wang, JC; Zhao, JP | 1 |
| Bacci, M; Bianchini, F; Cappellesso, F; Chiarugi, P; Comito, G; Ferracin, M; Gao, Q; Giannoni, E; Ippolito, L; Lorito, N; Luti, S; Marangoni, E; Martin, LA; Mazzone, M; Morandi, A; Parri, M; Ramazzotti, M; Romagnoli, S; Simões, BM; Virga, F | 1 |
| Chen, YC; Chuang, MT; Liu, YS; Tsai, YS; Wang, CK | 1 |
| Barańczyk-Kuźma, A; Chrzanowska, A; Graboń, W; Joniec-Maciejak, I; Mielczarek-Puta, M; Otto-Ślusarczyk, D; Słabik, K | 1 |
| Ciardiello, F; De Luca, A; Morgillo, F; Normanno, N; Tejpar, S; Van Cutsem, E | 1 |
| Ekholm, S; Germin, BI; Liu, X; Zhong, J | 1 |
| Batra, SK; Chakraborty, S; Jain, M; Kumar, S; Ponnusamy, MP; Rachagani, S; Senapati, S; Smith, LM | 1 |
| Fezoulidis, I; Fountas, K; Kapsalaki, E; Kousi, E; Svolos, P; Theodorou, K; Tsougos, I | 1 |
| Costa, S; Ferreira, P; Lopes, C; Medeiros, RM; Morais, A; Oliveira, J; Pinto, D; Vasconcelos, A | 1 |
| Fu, J; Li, F; Li, S; Peng, S; Wu, D; Yu, G | 1 |
| Hwang, YH; Park, SP; Suh, CK | 1 |
| Abbruzzese, JL; Ardalan, B; Balcerzak, SP; Benedetti, JK; Gaynor, ER; Macdonald, JS; Whitehead, RP; Williamson, S | 1 |
| Ramponi, G | 1 |
| Cristiani, C; Isacchi, A; Kalisz, HM; Knapp, S; Perego, R; Rusconi, L; Schiering, N | 1 |
| Capellà, G; Casanova, I; Cascante, M; Céspedes, MV; Guerrero, S; Mangues, R; Marcuello, E; Parreño, M; Pavón, MA; Sancho, FJ; Trias, M | 1 |
| Chawla, A; Emmanuel, JV; Lim, CC; Lou, J; Seow, WT; Teo, HE | 1 |
| Lavasanifar, A; Mahmud, A; Uludağ, H; Xiong, XB | 1 |
| Cocconi, G; Heuson, JC; Mouridsen, HT; Palshof, T; Paridaens, R; Rotmensz, N; Rozencweig, M; Sylvester, R; Van Oosterom, A | 1 |
| Kleeberg, UR; Voigt, H | 1 |
| Gertz, MA; Moertel, CG; O'Connell, MJ; Rubin, J; Schutt, AJ | 1 |
| Bundy, B; Creasman, WT; Muss, HB; Slavik, M; Stehman, FB | 1 |
| Gralla, RJ; Kelsen, DP; Natale, RB; Watson, RC; Yagoda, A | 1 |
| Buyse, M; Le Bourgeois, JP; Lévy, E; Piedbois, P | 1 |
| Arbuck, SG; Balis, F; Chisena, T; Cysyk, R; Drake, J; Grem, JL; Hamilton, JM; McAtee, N; Murphy, RF; Steinberg, SM | 1 |
| Calabrese, G; Falini, A; Lipari, S; Losa, M; Origgi, D; Scotti, G; Triulzi, F | 1 |
| Krygier, S; Luchtefeld, MA; Senagore, AJ; Thebo, JS | 1 |
| Li, F; Peng, S; Yu, G | 1 |
| Giga-Hama, Y; Goto, H; Isoai, A; Kumagai, H; Ueno, Y | 1 |
| Cillo, C; Hill, RP; Ling, V | 1 |
| Buroker, TR; Cullinan, SA; Everson, LK; Fleming, TR; Klaassen, DJ; Krook, JE; Laurie, JA; Mailliard, JA; Marschke, RF; Moertel, CG | 1 |
| Cillo, C; Dick, JE; Hill, RP; Ling, V | 1 |
| Camacho, FJ; Engstrom, PF; Green, MD; Greenwald, ES; Kaplan, BH; Muggia, FM; Wernz, JC | 1 |
| Buzdar, AU; Hortobagyi, GN; Mann, GB; Valdivieso, M; Yap, HY | 1 |
| Nieper, A | 1 |
3 review(s) available for aspartic acid and Metastase
| Article | Year |
|---|---|
Differentiating Radiation-Induced Necrosis from Recurrent Brain Tumor Using MR Perfusion and Spectroscopy: A Meta-Analysis.
Topics: Aspartic Acid; Blood Volume; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Humans; Magnetic Resonance Imaging; Necrosis; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prospective Studies; Radiation Injuries; Retrospective Studies | 2016 |
Implications for KRAS status and EGFR-targeted therapies in metastatic CRC.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Aspartic Acid; Base Sequence; Biomarkers, Tumor; Cetuximab; Codon; Colorectal Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Exons; Genes, ras; Humans; Molecular Sequence Data; Neoplasm Metastasis; Panitumumab; Patient Selection; Point Mutation; ras Proteins; Signal Transduction; Valine | 2009 |
[Chemotherapy of metastasizing cancers of the colon and rectum].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neoplasms; Fluorouracil; Humans; Interferons; Leucovorin; Methotrexate; Neoplasm Metastasis; Phosphonoacetic Acid; Rectal Neoplasms | 1993 |
4 trial(s) available for aspartic acid and Metastase
| Article | Year |
|---|---|
A phase II pilot study of high-dose 24-hour continuous infusion of 5-FU and leucovorin and low-dose PALA for patients with colorectal cancer: a Southwest Oncology Group study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Phosphonoacetic Acid; Pilot Projects; Survival Rate; Treatment Outcome | 2004 |
A phase I study of continuous infusion 5-fluorouracil plus calcium leucovorin in combination with N-(phosphonacetyl)-L-aspartate in metastatic gastrointestinal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartate Carbamoyltransferase; Aspartic Acid; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusions, Intravenous; Leucovorin; Male; Middle Aged; Monocytes; Neoplasm Metastasis; Phosphonoacetic Acid | 1993 |
A controlled evaluation of recent approaches to biochemical modulation or enhancement of 5-fluorouracil therapy in colorectal carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Levamisole; Male; Middle Aged; Neoplasm Metastasis; Phosphonoacetic Acid; Random Allocation; Rectal Neoplasms; Semustine; Streptozocin; Thymidine; Vincristine | 1985 |
A comparative study of PALA, PALA plus 5-FU, and 5-FU in advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Breast Neoplasms; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Metastasis; Organophosphorus Compounds; Phosphonoacetic Acid; Random Allocation | 1985 |
27 other study(ies) available for aspartic acid and Metastase
| Article | Year |
|---|---|
Multimodal MR Features of 8 Cases of Epithelioid Glioblastoma.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Cerebrovascular Circulation; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Edema; Epithelioid Cells; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Metastasis | 2020 |
Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer.
Topics: Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Aspartic Acid; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Excitatory Amino Acid Transporter 2; Female; Gas Chromatography-Mass Spectrometry; GATA2 Transcription Factor; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; Mice; Mice, Inbred BALB C; MicroRNAs; Neoplasm Metastasis; Prognosis; Transcriptome; Transplantation, Heterologous | 2019 |
Lactate Formation in Primary and Metastatic Colon Cancer Cells at Hypoxia and Normoxia.
Topics: Aspartate Aminotransferases; Aspartic Acid; Cell Count; Cell Hypoxia; Cell Line, Tumor; Colonic Neoplasms; Culture Media; Gene Expression Regulation, Neoplastic; Glucose; Humans; Lactic Acid; Models, Biological; Neoplasm Metastasis; Oxygen; RNA, Messenger; Serine | 2016 |
N-Acetyl peak in MR spectra of intracranial metastatic mucinous adenocarcinomas.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Aspartic Acid; Biopsy; Brain; Brain Neoplasms; Diagnostic Imaging; Female; Glioma; Glycoproteins; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Neoplasm Metastasis | 2010 |
Activated KrasG¹²D is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin.
Topics: Adenocarcinoma; Amino Acid Substitution; Animals; Aspartic Acid; Cadherins; Down-Regulation; Gene Expression Regulation, Neoplastic; Glycine; Humans; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Pancreatic Neoplasms; Point Mutation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; RNA, Small Interfering; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2011 |
Differentiation of glioblastoma multiforme from metastatic brain tumor using proton magnetic resonance spectroscopy, diffusion and perfusion metrics at 3 T.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Female; Glioblastoma; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Metastasis; Prospective Studies; ROC Curve | 2012 |
Outcome in prostate cancer: association with endothelial nitric oxide synthase Glu-Asp298 polymorphism at exon 7.
Topics: Aged; Aspartic Acid; Bone Neoplasms; Disease Progression; Exons; Genotype; Glutamic Acid; Humans; Logistic Models; Male; Middle Aged; Neoplasm Metastasis; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Polymorphism, Genetic; Prognosis; Prostatic Neoplasms; Treatment Outcome | 2002 |
[An antimetastatic study of Arg-Asp (RD) on salivary adenoid cystic carcinoma in vivo].
Topics: Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Carcinoma, Adenoid Cystic; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Salivary Gland Neoplasms | 2002 |
Multifocal inflammatory leukoencephalopathy: use of thallium-201 SPECT and proton MRS.
Topics: Adjuvants, Immunologic; Antimetabolites, Antineoplastic; Aspartic Acid; Axons; Biopsy; Brain; Brain Neoplasms; Choline; Colorectal Neoplasms; Diagnosis, Differential; Fluorouracil; Humans; Lactic Acid; Leukoencephalopathy, Progressive Multifocal; Levamisole; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Metastasis; Thallium Radioisotopes; Tomography, Emission-Computed, Single-Photon | 2003 |
Low molecular weight protein tyrosine phosphatase: catalytic mechanism and physiologic function.
Topics: Amino Acid Sequence; Animals; Arginine; Aspartic Acid; Cysteine; Mice; Molecular Weight; Mutagenesis, Site-Directed; Neoplasm Metastasis; NIH 3T3 Cells; Protein Tyrosine Phosphatases | 2004 |
Regulation of the wild-type and Y1235D mutant Met kinase activation.
Topics: Animals; Aspartic Acid; Base Sequence; Binding Sites; Carbazoles; Enzyme Inhibitors; Gene Silencing; Humans; Indole Alkaloids; Kinetics; Mutation; Neoplasm Metastasis; Phenotype; Phosphorylation; Phosphotyrosine; Protein Conformation; Proto-Oncogene Proteins c-met; Receptor Protein-Tyrosine Kinases; Recombinant Proteins; Transduction, Genetic; Tumor Cells, Cultured; Tyrosine | 2005 |
K-ras Asp12 mutant neither interacts with Raf, nor signals through Erk and is less tumorigenic than K-ras Val12.
Topics: Animals; Apoptosis; Aspartic Acid; Extracellular Signal-Regulated MAP Kinases; Male; Mice; Mice, Nude; Mutation; Neoplasm Metastasis; NIH 3T3 Cells; Oncogene Protein p21(ras); Protein Binding; Proto-Oncogene Proteins c-raf; Signal Transduction; Valine | 2006 |
Paediatric PNET: pre-surgical MRI features.
Topics: Aspartic Acid; Cerebrospinal Fluid; Child; Child, Preschool; Choline; Creatine; Databases, Factual; Diffusion Magnetic Resonance Imaging; Female; Gadolinium DTPA; Humans; Image Enhancement; Infant; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Medulloblastoma; Neoplasm Metastasis; Neuroectodermal Tumors, Primitive; Supratentorial Neoplasms; Taurine | 2007 |
Conjugation of arginine-glycine-aspartic acid peptides to poly(ethylene oxide)-b-poly(epsilon-caprolactone) micelles for enhanced intracellular drug delivery to metastatic tumor cells.
Topics: Aldehydes; Arginine; Aspartic Acid; Cell Line, Tumor; Drug Delivery Systems; Glycine; Humans; Lactones; Micelles; Microscopy, Confocal; Microscopy, Fluorescence; Models, Chemical; Neoplasm Metastasis; Neoplasms; Peptides; Polyethylene Glycols | 2007 |
N-(phosphonacetyl)-L-aspartate (PALA) in advanced breast cancer: a phase II trial of the EORTC breast cancer cooperative group.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Aspartic Acid; Breast Neoplasms; Digestive System; Drug Eruptions; Drug Evaluation; Female; Humans; Infusions, Parenteral; Middle Aged; Neoplasm Metastasis; Organophosphorus Compounds; Phosphonoacetic Acid | 1982 |
PALA, vindesine, and cisplatin combination chemotherapy in advanced malignant melanoma. A pilot study.
Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Bone Marrow; Cisplatin; Drug Eruptions; Female; Humans; Male; Melanoma; Middle Aged; Nausea; Neoplasm Metastasis; Phosphonoacetic Acid; Pilot Projects; Vinblastine; Vindesine; Vomiting | 1984 |
A phase II study of the combination, 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and N-(phosphonacetyl)-L-aspartate (PALA), in patients with advanced large bowel cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Carmustine; Colonic Neoplasms; Drug Evaluation; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Phosphonoacetic Acid; Rectal Neoplasms | 1984 |
A phase II study of PALA (NSC 224131) in patients with advanced ovarian carcinoma. A Gynecologic Oncology Group study.
Topics: Adult; Aged; Aspartic Acid; Blood Cell Count; Drug Evaluation; Female; Humans; Middle Aged; Neoplasm Metastasis; Organophosphorus Compounds; Ovarian Neoplasms; Phosphonoacetic Acid; Skin Diseases; Time Factors | 1984 |
Phase II trial of PALA in hypernephroma and urinary bladder cancer.
Topics: Adenocarcinoma; Aspartic Acid; Drug Evaluation; Humans; Kidney Neoplasms; Neoplasm Metastasis; Organophosphorus Compounds; Phosphonoacetic Acid; Urinary Bladder Neoplasms | 1982 |
Proton magnetic resonance spectroscopy and intracranial tumours: clinical perspectives.
Topics: Adenoma; Aspartic Acid; Brain Neoplasms; Choline; Craniopharyngioma; Creatinine; Glioma; Humans; Lymphoma; Magnetic Resonance Spectroscopy; Meningioma; Neoplasm Metastasis | 1996 |
K-ras mutational analysis of polyclonal colorectal cancers identifies uniclonal circulating tumor cells.
Topics: Aspartic Acid; Colorectal Neoplasms; Disease Progression; DNA Mutational Analysis; Genes, ras; Glycine; Humans; Neoplasm Metastasis; Neoplastic Cells, Circulating; Polymerase Chain Reaction | 2001 |
[Antimetastatic effects of arginine-aspartate on salivary adenoid cystic carcinoma in vitro].
Topics: Antineoplastic Agents; Arginine; Aspartic Acid; Carcinoma, Adenoid Cystic; Cell Adhesion; Extracellular Matrix; Humans; Neoplasm Metastasis; Salivary Gland Neoplasms | 2001 |
A novel Arg-Gly-Asp containing peptide specific for platelet aggregation and its effect on tumor metastasis: a possible mechanism of RGD peptide-mediated inhibition of tumor metastasis.
Topics: Animals; Anticarcinogenic Agents; Arginine; Aspartic Acid; Carcinoma, Squamous Cell; Cell Adhesion; Collagen; Female; Fibronectins; Glycine; Glycoproteins; Lung Neoplasms; Mice; Mice, Inbred C3H; Neoplasm Metastasis; Oligopeptides; Peptides, Cyclic; Platelet Aggregation; Protein Binding; Vitronectin | 1992 |
Drug resistance in KHT fibrosarcoma cell lines with different metastatic ability.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Cell Line; Drug Resistance; Fibrosarcoma; Gene Amplification; Methotrexate; Mice; Neoplasm Metastasis; Organophosphorus Compounds; Phosphonoacetic Acid | 1989 |
Generation of drug-resistant variants in metastatic B16 mouse melanoma cell lines.
Topics: Animals; Aspartic Acid; Cell Line; Drug Resistance; Gene Amplification; Mathematics; Melanoma; Methotrexate; Mice; Neoplasm Metastasis; Organophosphorus Compounds; Phenotype; Phosphonoacetic Acid | 1987 |
Weekly 5-fluorouracil combined with PALA: toxic and therapeutic effects in colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Central Nervous System Diseases; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Diseases; Hematologic Diseases; Humans; Male; Middle Aged; Neoplasm Metastasis; Phosphonoacetic Acid; Pilot Projects; Rectal Neoplasms | 1987 |
Recalcification of bone metastases by calcium diorotate.
Topics: Adult; Aspartic Acid; Biological Transport, Active; Bone and Bones; Bone Neoplasms; Breast Neoplasms; Calcification, Physiologic; Calciphylaxis; Calcium; Decalcification, Pathologic; Female; Humans; Neoplasm Metastasis; Orotic Acid; Phosphoric Acids | 1970 |