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aspartic acid and Mental Disorders

aspartic acid has been researched along with Mental Disorders in 19 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.

Research Excerpts

ExcerptRelevanceReference
"For the major adult neuropsychiatric disorders (schizophrenia, bipolar disorder, major depression, and the anxiety disorders), we highlight the most consistent MRS findings, with an emphasis on those with potential clinical or translational significance."2.48MR spectroscopic studies of the brain in psychiatric disorders. ( Buonocore, MH; Maddock, RJ, 2012)
"Patients with advanced Parkinson's disease (PD) commonly suffer with significant executive dysfunction and concomitant visual hallucinations."1.38Anterior cingulate integrity: executive and neuropsychiatric features in Parkinson's disease. ( Duffy, S; Halliday, G; Lewis, SJ; Naismith, SL; Shine, JM, 2012)
"The deficits of Alzheimer's disease (AD) are believed to result, at least in part, from neurotoxicity of beta-amyloid (Abeta), a set of 38-43 amino acid fragments derived from the beta-amyloid precursor protein (APP)."1.35Long-term prevention of Alzheimer's disease-like behavioral deficits in PDAPP mice carrying a mutation in Asp664. ( Ataie, M; Banwait, S; Bredesen, DE; Galvan, V; Gorostiza, OF; Huang, W; Tang, H; Zhang, J, 2008)
"The cognitive decline in Alzheimer's disease (AD) patients has been reported to involve alterations in the medial temporal lobe and the posterior cingulate gyrus."1.34A decrease in N-acetylaspartate and an increase in myoinositol in the anterior cingulate gyrus are associated with behavioral and psychological symptoms in Alzheimer's disease. ( Horiguchi, J; Inagaki, T; Inami, Y; Kawamukai, T; Miyaoka, T; Okazaki, S; Shinno, H; Utani, E, 2007)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19906 (31.58)18.7374
1990's0 (0.00)18.2507
2000's6 (31.58)29.6817
2010's6 (31.58)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Uchida, M1
Noda, Y1
Hasegawa, S1
Hida, H1
Taniguchi, M1
Mouri, A1
Yoshimi, A1
Nabeshima, T1
Yamada, K1
Aida, T1
Tanaka, K1
Ozaki, N1
Cho, YU1
Lee, D1
Lee, JE1
Kim, KH1
Lee, DY1
Jung, YC1
Paslakis, G1
Träber, F1
Roberz, J1
Block, W1
Jessen, F1
Baymeeva, NV1
Miroshnichenko, II1
Machado, A1
Soares-Fernandes, J1
Ribeiro, M1
Rodrigues, M1
Cerqueira, J1
Ferreira, C1
Capizzano, AA1
Jorge, RE1
Robinson, RG1
Maddock, RJ1
Buonocore, MH1
Lewis, SJ1
Shine, JM1
Duffy, S1
Halliday, G1
Naismith, SL1
BARUK, H1
FABIANI, P1
NAGLE, FJ1
BALKE, B1
GANSLEN, RV1
DAVIS, AW1
RABASSINI, A1
Mason, GF1
Krystal, JH1
Yücel, M1
Harrison, BJ1
Wood, SJ1
Fornito, A1
Clarke, K1
Wellard, RM1
Cotton, S1
Pantelis, C1
Shinno, H1
Inagaki, T1
Miyaoka, T1
Okazaki, S1
Kawamukai, T1
Utani, E1
Inami, Y1
Horiguchi, J1
Galvan, V1
Zhang, J1
Gorostiza, OF1
Banwait, S1
Huang, W1
Ataie, M1
Tang, H1
Bredesen, DE1
Chapman, A1
Keane, PE1
Meldrum, BS1
Simiand, J1
Vernieres, JC1
van der Knaap, MS1
Verhoeven, NM1
Maaswinkel-Mooij, P1
Pouwels, PJ1
Onkenhout, W1
Peeters, EA1
Stöckler-Ipsiroglu, S1
Jakobs, C1
Parkes, JD1
Fenton, G1
Struthers, G1
Curzon, G1
Kantamaneni, BD1
Buxton, BH1
Record, C1
Jenner, FA1

Reviews

5 reviews available for aspartic acid and Mental Disorders

ArticleYear
N-acetyl-aspartate (NAA) as a correlate of pharmacological treatment in psychiatric disorders: a systematic review.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:10

    Topics: Aspartic Acid; Brain; Humans; Mental Disorders; Proton Magnetic Resonance Spectroscopy

2014
[N-acetylaspartate is a biomarker of psychiatric and neurological disorders].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:8

    Topics: Aspartic Acid; Biomarkers; Brain Chemistry; Humans; Magnetic Resonance Spectroscopy; Mental Disorder

2015
MR spectroscopic studies of the brain in psychiatric disorders.
    Current topics in behavioral neurosciences, 2012, Volume: 11

    Topics: Aspartic Acid; Brain; Creatine; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; M

2012
MR spectroscopy: its potential role for drug development for the treatment of psychiatric diseases.
    NMR in biomedicine, 2006, Volume: 19, Issue:6

    Topics: Aspartic Acid; Biomarkers; Choline; Drug Evaluation; Humans; Inositol; Magnetic Resonance Spectrosco

2006
Mechanism of anticonvulsant action of valproate.
    Progress in neurobiology, 1982, Volume: 19, Issue:4

    Topics: Animals; Aspartic Acid; Cats; Central Nervous System; Epilepsy; gamma-Aminobutyric Acid; Half-Life;

1982

Other Studies

14 other studies available for aspartic acid and Mental Disorders

ArticleYear
Early postnatal inhibition of GLAST causes abnormalities of psychobehaviors and neuronal morphology in adult mice.
    Neurochemistry international, 2021, Volume: 150

    Topics: Animals; Animals, Newborn; Aspartic Acid; Excitatory Amino Acid Transporter 1; Female; Injections, I

2021
Exploratory metabolomics of biomarker identification for the internet gaming disorder in young Korean males.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017, Jul-01, Volume: 1057

    Topics: Aspartic Acid; Behavior, Addictive; Biomarkers; Blood Chemical Analysis; Gas Chromatography-Mass Spe

2017
Alcohol abuse and acute behavioural disturbances in a 24-year-old patient. Diagnosis: Marchiafava-Bignami disease (MBD).
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009, Volume: 16, Issue:6

    Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Aspartic Acid; Choline; Corpus Callosum; Crea

2009
Limbic metabolic abnormalities in remote traumatic brain injury and correlation with psychiatric morbidity and social functioning.
    The Journal of neuropsychiatry and clinical neurosciences, 2010,Fall, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Diseases, Metabolic; Brain Injuries; Brain Mapping; Ca

2010
Anterior cingulate integrity: executive and neuropsychiatric features in Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2012, Sep-01, Volume: 27, Issue:10

    Topics: Aged; Aspartic Acid; Case-Control Studies; Cognition Disorders; Creatine; Female; Gyrus Cinguli; Hum

2012
[Supplementary note on hyperammoniemia in various psychoses (Parelleism of biliary hypertoxicity, hyperammoniemia and increase in the optical density of the bile].
    Annales medico-psychologiques, 1963, Volume: 121(1)

    Topics: Aspartic Acid; Bile; Humans; Hyperammonemia; Mental Disorders; Psychotic Disorders

1963
THE MITIGATION OF PHYSICAL FATIGUE WITH "SPARTASE". REP 63-12.
    [Report]. Civil Aeromedical Research Institute (U.S.), 1963

    Topics: Aspartic Acid; Biomedical Research; Exercise Test; Fatigue; Magnesium; Mental Disorders; Pharmacolog

1963
[MEMORY-STIMULATING EFFECT OF A RIBONUCLEOTIDE COMPLEX IN SENILE SYNDROMES AND CONFUSIONAL STATES INDUCED BY ELCTROSHOCK].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1964, Jun-30, Volume: 88

    Topics: Arginine; Aspartic Acid; Biomedical Research; Confusion; Drug Therapy; Electroconvulsive Therapy; Fl

1964
State, trait and biochemical influences on human anterior cingulate function.
    NeuroImage, 2007, Feb-15, Volume: 34, Issue:4

    Topics: Adult; Aspartic Acid; Brain Mapping; Conflict, Psychological; Female; Functional Laterality; Gyrus C

2007
A decrease in N-acetylaspartate and an increase in myoinositol in the anterior cingulate gyrus are associated with behavioral and psychological symptoms in Alzheimer's disease.
    Journal of the neurological sciences, 2007, Sep-15, Volume: 260, Issue:1-2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Brain Chemistry; Cognition Disorders; Cre

2007
Long-term prevention of Alzheimer's disease-like behavioral deficits in PDAPP mice carrying a mutation in Asp664.
    Behavioural brain research, 2008, Aug-22, Volume: 191, Issue:2

    Topics: Age Factors; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Anal

2008
Mental retardation and behavioral problems as presenting signs of a creatine synthesis defect.
    Annals of neurology, 2000, Volume: 47, Issue:4

    Topics: Aspartic Acid; Body Fluids; Brain Diseases, Metabolic; Child, Preschool; Creatine; Diagnosis, Differ

2000
Narcolepsy and cataplexy. Clinical features, treatment and cerebrospinal fluid findings.
    The Quarterly journal of medicine, 1974, Volume: 43, Issue:172

    Topics: Adult; Amphetamine; Aspartic Acid; Body Weight; Cataplexy; Cerebrospinal Fluid Proteins; Dextroamphe

1974
Medical research council unit for metabolic studies in psychiatry, Sheffield.
    Psychological medicine, 1973, Volume: 3, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Bipolar Disorder; Catatonia; Circadian Rhythm;

1973