Page last updated: 2024-11-08

aspartic acid and Meningioma

aspartic acid has been researched along with Meningioma in 24 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Meningioma: A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)

Research Excerpts

ExcerptRelevanceReference
" MRS of normal brain parenchyma displays 4 main metabolites: N-acetyl aspartate (neuronal marker), creatine (cellular density marker), choline (membrane activity marker) and myoinositol (glial marker); pathological processes lead to variations of the level of these metabolites and/or the appearance of abnormal metabolites (lactate), following different patterns according to pathological process involved: glioma, meningioma, metastasis, bacterial or toxoplasmic abscess, radionecrosis."3.71[Contribution of magnetic resonance spectrometry to the diagnosis of intracranial tumors]. ( Confort-Gouny, S; Cozzone, PJ; Dufour, H; Galanaud, D; Le Fur, Y; Nicoli, F; Peragut, JC; Ranjeva, JP; Roche, P; Viout, P, 2002)
" All high-grade gliomas (n = 37) showed high choline and low or absent N-acetyl-L-aspartate and creatine along with lipid and/or lactate, whereas low-grade gliomas (n = 23) were characterized by low N-acetyl-aspartate and creatine and high choline and presence of only lactate."3.69Characterization of intracranial mass lesions with in vivo proton MR spectroscopy. ( Chhabra, DK; Gupta, RK; Jain, VK; Pandey, R; Poptani, H; Roy, R, 1995)
" The NAA (N-acetylaspartate)/Cho (choline) ratio of Grade 2 astrocytoma was higher than that of Grade 4."3.69Non-invasive characterization of brain tumor by in-vivo proton magnetic resonance spectroscopy. ( Bandou, K; Harada, M; Kannuki, S; Miyoshi, H; Nishitani, H; Tanouchi, M, 1995)
" Oligodendrogliomas had higher choline levels than astrocytomas."3.68[1H magnetic resonance spectroscopy in intracranial tumors and cerebral ischemia]. ( Felber, SR, 1993)
"We examined 120 patients with brain tumors using a 1."1.31In vivo proton magnetic resonance spectroscopy of brain tumors. ( Fountas, KN; Gotsis, SD; Johnston, KW; Kapsalaki, EZ; Kapsalakis, JZ; Papadakis, N; Robinson, JS; Smisson , HF, 2000)
"Seventeen brain tumors were measured by 1H-CSI (chemical shift imaging) in a 1."1.30Evaluation of metabolic heterogeneity in brain tumors using 1H-chemical shift imaging method. ( Furuya, S; Ide, M; Kizu, O; Maeda, T; Morishita, H; Naruse, S; Ueda, S, 1997)
"Meningiomas were further characterized by the presence of alanine."1.29Determination of proton metabolite concentrations and relaxation parameters in normal human brain and intracranial tumours. ( Blackband, SJ; Horsman, A; Lowry, M; Manton, DJ, 1995)
"Higher grades of brain tumors in this study were associated with higher Cho/reference and lower NAA/reference values."1.29Noninvasive evaluation of malignancy of brain tumors with proton MR spectroscopy. ( Arai, N; Fujiwara, S; Hara, K; Kayama, T; Kumabe, T; Ono, Y; Sato, K; Shimizu, H; Tominaga, T; Yoshimoto, T, 1996)
"Seventy patients with intracranial neoplasms were studied before receiving surgery, radiotherapy or chemotherapy."1.29Proton magnetic resonance spectroscopy and intracranial tumours: clinical perspectives. ( Calabrese, G; Falini, A; Lipari, S; Losa, M; Origgi, D; Scotti, G; Triulzi, F, 1996)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.50)18.7374
1990's10 (41.67)18.2507
2000's7 (29.17)29.6817
2010's3 (12.50)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
De Stefano, FA1
Morell, AA1
Smith, G1
Warner, T1
Soldozy, S1
Elarjani, T1
Eichberg, DG1
Luther, E1
Komotar, RJ1
Lin, MC1
Li, CZ1
Hsieh, CC1
Hong, KT1
Lin, BJ1
Lin, C1
Tsai, WC1
Lee, CH1
Lee, MG1
Chung, TT1
Tang, CT1
Ju, DT1
Ma, HI1
Liu, MY1
Chen, YH1
Hueng, DY1
Stadler, KL1
Ober, CP1
Feeney, DA1
Jessen, CR1
Chernov, MF1
Nakaya, K1
Kasuya, H1
Kato, K1
Ono, Y2
Yoshida, S1
Nakamura, R1
Suzuki, T1
Muragaki, Y1
Iseki, H1
Kubo, O1
Hori, T1
Takakura, K1
Righi, V1
Tugnoli, V1
Mucci, A1
Bacci, A1
Bonora, S1
Schenetti, L1
Howe, FA1
Barton, SJ1
Cudlip, SA1
Stubbs, M1
Saunders, DE1
Murphy, M1
Wilkins, P1
Opstad, KS1
Doyle, VL1
McLean, MA1
Bell, BA1
Griffiths, JR1
Bulakbasi, N1
Kocaoglu, M1
Ors, F1
Tayfun, C1
Uçöz, T1
Galanaud, D1
Nicoli, F1
Le Fur, Y1
Roche, P1
Confort-Gouny, S1
Dufour, H1
Ranjeva, JP1
Peragut, JC1
Viout, P1
Cozzone, PJ1
Dydak, U1
Meier, D1
Lamerichs, R1
Boesiger, P1
Poptani, H1
Gupta, RK1
Roy, R1
Pandey, R1
Jain, VK1
Chhabra, DK1
Harada, M1
Tanouchi, M1
Nishitani, H1
Miyoshi, H1
Bandou, K1
Kannuki, S1
Kamada, K1
Houkin, K1
Hida, K1
Matsuzawa, H1
Iwasaki, Y1
Abe, H1
Nakada, T1
Felber, SR1
Manton, DJ1
Lowry, M1
Blackband, SJ1
Horsman, A1
Preul, MC1
Caramanos, Z1
Collins, DL1
Villemure, JG1
Leblanc, R1
Olivier, A1
Pokrupa, R1
Arnold, DL1
Shimizu, H1
Kumabe, T1
Tominaga, T1
Kayama, T1
Hara, K1
Sato, K1
Arai, N1
Fujiwara, S1
Yoshimoto, T1
Falini, A1
Calabrese, G1
Origgi, D1
Lipari, S1
Triulzi, F1
Losa, M1
Scotti, G1
Furuya, S1
Naruse, S1
Ide, M1
Morishita, H1
Kizu, O1
Ueda, S1
Maeda, T1
Fountas, KN1
Kapsalaki, EZ1
Gotsis, SD1
Kapsalakis, JZ1
Smisson , HF1
Johnston, KW1
Robinson, JS1
Papadakis, N1
Bendszus, M1
Warmuth-Metz, M1
Burger, R1
Klein, R1
Tonn, JC1
Solymosi, L1
Henriksen, O1
Wieslander, S1
Gjerris, F1
Jensen, KM1
Bruhn, H1
Frahm, J1
Gyngell, ML1
Merboldt, KD1
Hänicke, W1
Sauter, R1
Hamburger, C1
Nadler, JV1
Cooper, JR1
Fischer, W1
Müller, E1

Reviews

1 review available for aspartic acid and Meningioma

ArticleYear
Unique magnetic resonance spectroscopy profile of intracranial meningiomas compared to gliomas: a systematic review.
    Acta neurologica Belgica, 2023, Volume: 123, Issue:6

    Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Magnetic Resonance Spectr

2023

Other Studies

23 other studies available for aspartic acid and Meningioma

ArticleYear
Preoperative grading of intracranial meningioma by magnetic resonance spectroscopy (1H-MRS).
    PloS one, 2018, Volume: 13, Issue:11

    Topics: Adult; Aged; Aspartic Acid; Choline; Creatine; Female; Humans; Male; Meningeal Neoplasms; Meningioma

2018
Multivoxel proton magnetic resonance spectroscopy of inflammatory and neoplastic lesions of the canine brain at 3.0 T.
    American journal of veterinary research, 2014, Volume: 75, Issue:11

    Topics: Analysis of Variance; Animals; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis,

2014
Metabolic alterations in the peritumoral brain in cases of meningiomas: 1H-MRS study.
    Journal of the neurological sciences, 2009, Sep-15, Volume: 284, Issue:1-2

    Topics: Adult; Aged; Aspartic Acid; Brain; Brain Edema; Choline; Female; Humans; Lactic Acid; Lipids; Magnet

2009
MRS study of meningeal hemangiopericytoma and edema: a comparison with meningothelial meningioma.
    Oncology reports, 2012, Volume: 28, Issue:4

    Topics: 3-Hydroxybutyric Acid; Alanine; Aspartic Acid; Brain Edema; Choline; Creatine; Glutamic Acid; Glutat

2012
Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy.
    Magnetic resonance in medicine, 2003, Volume: 49, Issue:2

    Topics: Alanine; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Glioblastoma; Humans; Inosi

2003
Combination of single-voxel proton MR spectroscopy and apparent diffusion coefficient calculation in the evaluation of common brain tumors.
    AJNR. American journal of neuroradiology, 2003, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creat

2003
[Contribution of magnetic resonance spectrometry to the diagnosis of intracranial tumors].
    Annales de medecine interne, 2002, Volume: 153, Issue:8

    Topics: Aspartic Acid; Biomarkers; Brain Abscess; Brain Neoplasms; Choline; Computer Graphics; Creatine; Dia

2002
Trading spectral separation at 3T for acquisition speed in multi spin-echo spectroscopic imaging.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:7

    Topics: Aspartic Acid; Brain; Choline; Creatine; Humans; Image Enhancement; Image Processing, Computer-Assis

2006
Characterization of intracranial mass lesions with in vivo proton MR spectroscopy.
    AJNR. American journal of neuroradiology, 1995, Volume: 16, Issue:8

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Child; Choline; Crea

1995
Non-invasive characterization of brain tumor by in-vivo proton magnetic resonance spectroscopy.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:3

    Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Ependymoma; Glioma; Humans; Magnetic

1995
Localized proton spectroscopy of focal brain pathology in humans: significant effects of edema on spin-spin relaxation time.
    Magnetic resonance in medicine, 1994, Volume: 31, Issue:5

    Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Edema; Brain Ischemia; Brain Neoplasms; Cerebr

1994
[1H magnetic resonance spectroscopy in intracranial tumors and cerebral ischemia].
    Der Radiologe, 1993, Volume: 33, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Ischemia; Child; Child, Preschool;

1993
Determination of proton metabolite concentrations and relaxation parameters in normal human brain and intracranial tumours.
    NMR in biomedicine, 1995, Volume: 8, Issue:3

    Topics: Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cerebellum; Creatine; Humans; Magnetic Resonance

1995
Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy.
    Nature medicine, 1996, Volume: 2, Issue:3

    Topics: Adult; Alanine; Aspartic Acid; Astrocytoma; Biomarkers; Brain; Brain Neoplasms; Choline; Creatine; D

1996
Noninvasive evaluation of malignancy of brain tumors with proton MR spectroscopy.
    AJNR. American journal of neuroradiology, 1996, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Energy Metabolism; Femal

1996
Proton magnetic resonance spectroscopy and intracranial tumours: clinical perspectives.
    Journal of neurology, 1996, Volume: 243, Issue:10

    Topics: Adenoma; Aspartic Acid; Brain Neoplasms; Choline; Craniopharyngioma; Creatinine; Glioma; Humans; Lym

1996
Evaluation of metabolic heterogeneity in brain tumors using 1H-chemical shift imaging method.
    NMR in biomedicine, 1997, Volume: 10, Issue:1

    Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Evaluation Studies as Topic; Glioma; Humans; Imag

1997
In vivo proton magnetic resonance spectroscopy of brain tumors.
    Stereotactic and functional neurosurgery, 2000, Volume: 74, Issue:2

    Topics: Adult; Aged; Amino Acids; Aspartic Acid; Astrocytoma; Brain; Brain Abscess; Brain Neoplasms; Choline

2000
Diagnosing dural metastases: the value of 1H magnetic resonance spectroscopy.
    Neuroradiology, 2001, Volume: 43, Issue:4

    Topics: Aged; Angiography; Aspartic Acid; Choline; Contrast Media; Creatine; Dura Mater; Female; Humans; Lac

2001
In vivo 1H-spectroscopy of human intracranial tumors at 1.5 tesla. Preliminary experience at a clinical installation.
    Acta radiologica (Stockholm, Sweden : 1987), 1991, Volume: 32, Issue:2

    Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Female; Humans; Lactate

1991
Noninvasive differentiation of tumors with use of localized H-1 MR spectroscopy in vivo: initial experience in patients with cerebral tumors.
    Radiology, 1989, Volume: 172, Issue:2

    Topics: Adult; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplasms; Choline; Creatinine; Cysts;

1989
N-acetyl-L-aspartic acid content of human neural tumours and bovine peripheral nervous tissues.
    Journal of neurochemistry, 1972, Volume: 19, Issue:2

    Topics: Animals; Aspartic Acid; Brain Neoplasms; Cattle; Cerebral Cortex; Craniopharyngioma; Glioblastoma; G

1972
[Activities of glutamate dehydrogenase and aspartate aminotransferase in human brain tumors].
    Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie, 1972, Volume: 115, Issue:1

    Topics: Adenoma; Aspartate Aminotransferases; Aspartic Acid; Astrocytoma; Biopsy; Brain Neoplasms; Craniopha

1972