aspartic acid has been researched along with Medulloblastoma in 12 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Medulloblastoma: A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Medulloblastoma is a cancerous brain tumor that affects mostly children." | 5.91 | The mitochondrial NADH shuttle system is a targetable vulnerability for Group 3 medulloblastoma in a hypoxic microenvironment. ( Ben-Sahra, I; Bost, F; Contenti, J; Guo, Y; Irondelle, M; Lago, C; Leva, G; Mazure, NM; Mazzu, A; Rouleau, M; Tiberi, L, 2023) |
| " MRS (two patients with medulloblastoma and one with a SPNET), showed elevated choline, decreased N-acetyl aspartate, and a small taurine peak in all three patients." | 3.74 | Paediatric PNET: pre-surgical MRI features. ( Chawla, A; Emmanuel, JV; Lim, CC; Lou, J; Seow, WT; Teo, HE, 2007) |
| " The concentration of taurine (Tau) in medulloblastomas was 29." | 3.72 | In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard. ( Harada, K; Houkin, K; Tong, Z; Yamaki, T, 2004) |
| " The concentration of taurine (Tau) in medulloblastomas was 29." | 3.72 | In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard. ( Harada, K; Houkin, K; Tong, Z; Yamaki, T, 2004) |
| "Medulloblastoma is a cancerous brain tumor that affects mostly children." | 1.91 | The mitochondrial NADH shuttle system is a targetable vulnerability for Group 3 medulloblastoma in a hypoxic microenvironment. ( Ben-Sahra, I; Bost, F; Contenti, J; Guo, Y; Irondelle, M; Lago, C; Leva, G; Mazure, NM; Mazzu, A; Rouleau, M; Tiberi, L, 2023) |
| "Proton MRS of pediatric posterior fossa tumors seems to be helpful in prediction of tumor grading and histology." | 1.31 | [Clinical application of proton magnetic resonance spectroscopy for differential diagnosis of pediatric posterior fossa tumors]. ( Biegański, T; Kreisel, J; Liberski, PP; Nowosławska, E; Polis, L; Zakrzewski, K, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Contenti, J | 1 |
| Guo, Y | 1 |
| Mazzu, A | 1 |
| Irondelle, M | 1 |
| Rouleau, M | 1 |
| Lago, C | 1 |
| Leva, G | 1 |
| Tiberi, L | 1 |
| Ben-Sahra, I | 1 |
| Bost, F | 1 |
| Mazure, NM | 1 |
| Carlin, D | 1 |
| Babourina-Brooks, B | 1 |
| Davies, NP | 1 |
| Wilson, M | 1 |
| Peet, AC | 1 |
| Yoshimura, J | 1 |
| Nishiyama, K | 1 |
| Fukuda, M | 1 |
| Watanabe, M | 1 |
| Igarashi, H | 1 |
| Fujii, Y | 1 |
| Blamek, S | 1 |
| Larysz, D | 1 |
| Ficek, K | 1 |
| Sokół, M | 1 |
| Miszczyk, L | 1 |
| Tarnawski, R | 1 |
| Rueckriegel, SM | 1 |
| Driever, PH | 1 |
| Bruhn, H | 1 |
| Tong, Z | 2 |
| Yamaki, T | 2 |
| Harada, K | 2 |
| Houkin, K | 2 |
| Chawla, A | 1 |
| Emmanuel, JV | 1 |
| Seow, WT | 1 |
| Lou, J | 1 |
| Teo, HE | 1 |
| Lim, CC | 1 |
| Sutton, LN | 1 |
| Wehrli, SL | 1 |
| Gennarelli, L | 1 |
| Wang, Z | 1 |
| Zimmerman, R | 1 |
| Bonner, K | 1 |
| Rorke, LB | 1 |
| Wilke, M | 1 |
| Eidenschink, A | 1 |
| Müller-Weihrich, S | 1 |
| Auer, DP | 1 |
| Zakrzewski, K | 1 |
| Kreisel, J | 1 |
| Polis, L | 1 |
| Nowosławska, E | 1 |
| Liberski, PP | 1 |
| Biegański, T | 1 |
| Nadler, JV | 1 |
| Cooper, JR | 1 |
12 other studies available for aspartic acid and Medulloblastoma
| Article | Year |
|---|---|
The mitochondrial NADH shuttle system is a targetable vulnerability for Group 3 medulloblastoma in a hypoxic microenvironment.
Topics: Aspartic Acid; Cerebellar Neoplasms; Child; Humans; Hypoxia; Malates; Medulloblastoma; NAD; Oxygen; | 2023 |
Variation of T
Topics: Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Child; Choline; Creatine; Female; Humans; Magnet | 2019 |
Adult cerebellopontine angle medulloblastoma originating in the pons mimicking focal brainstem tumor.
Topics: Adult; Aspartic Acid; Brain Stem Neoplasms; Cerebellopontine Angle; Choline; Diagnosis, Differential | 2009 |
MR spectroscopic evaluation of brain tissue damage after treatment for pediatric brain tumors.
Topics: Adolescent; Aspartic Acid; Brain; Brain Neoplasms; Child; Choline; Creatine; Ependymoma; Female; Gli | 2010 |
Supratentorial neurometabolic alterations in pediatric survivors of posterior fossa tumors.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Astro | 2012 |
In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cerebellar Neoplasms; C | 2004 |
In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard.
Topics: Adult; Aged; Aspartic Acid; Body Water; Brain; Brain Neoplasms; Child; Child, Preschool; Choline; Cr | 2004 |
Paediatric PNET: pre-surgical MRI features.
Topics: Aspartic Acid; Cerebrospinal Fluid; Child; Child, Preschool; Choline; Creatine; Databases, Factual; | 2007 |
High-resolution 1H-magnetic resonance spectroscopy of pediatric posterior fossa tumors in vitro.
Topics: Adolescent; Alanine; Amino Acids; Animals; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cerebellar N | 1994 |
MR diffusion imaging and 1H spectroscopy in a child with medulloblastoma. A case report.
Topics: Aspartic Acid; Cerebellar Neoplasms; Child, Preschool; Diagnosis, Differential; Female; Humans; Magn | 2001 |
[Clinical application of proton magnetic resonance spectroscopy for differential diagnosis of pediatric posterior fossa tumors].
Topics: Adolescent; Aspartic Acid; Astrocytoma; Child; Child, Preschool; Choline; Creatine; Diagnosis, Diffe | 2001 |
N-acetyl-L-aspartic acid content of human neural tumours and bovine peripheral nervous tissues.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Cattle; Cerebral Cortex; Craniopharyngioma; Glioblastoma; G | 1972 |