aspartic acid has been researched along with Malignant Melanoma in 37 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 17 (45.95) | 18.7374 |
1990's | 5 (13.51) | 18.2507 |
2000's | 7 (18.92) | 29.6817 |
2010's | 5 (13.51) | 24.3611 |
2020's | 3 (8.11) | 2.80 |
Authors | Studies |
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Chen, Z; Dong, X; Shi, Y; Wang, H; Yu, Z; Zhao, W; Zhu, Q | 1 |
Balakin, A; Novak, P; Temnik, M | 1 |
Chen, X; Deng, M; He, Y; Liu, Y; Sun, S; Wan, H; Wang, J; Wen, J; Xu, J; Xu, Y; Yan, L | 1 |
Feng, Y; Fujita, Y; Herlyn, M; Osterman, AL; Pathria, G; Ronai, ZA; Ruppin, E; Sahu, AD; Sang Lee, J; Scott, DA; Zhang, G | 1 |
Gomez, GVB; Lima, CSP; Lourenço, GJ; Moraes, AM; Oliveira, C; Rinck-Junior, JA; Torricelli, C | 1 |
Aranda, AS; Carrillo, DA; Gutierrez, DA; Koshlaychuk, MA; Lombardo, MC; Lucena, SE; McBride, TD; Medina, SM; Medrano, R; Ramos, CJ; Sanchez, EE; Soto, JG; U, A | 1 |
Brunet, JP; Fisher, DE; Golub, TR; Jalili, A; Lupien, M; Mertz, KD; Pashenkov, M; Pathria, G; Ramaswamy, S; Stingl, G; Wagner, C; Wagner, SN; Widlund, HR | 1 |
Cresswell, P; Graham, M; Hee, JS; Leonhardt, RM; Vigneron, N | 1 |
Chapman, PB; Wolchok, JD | 1 |
Drauz, K; Fields, GB; Lauer-Fields, JL; Malkar, NB; Richet, G | 1 |
Bagayogo, I; Chao, M; Hempstead, B; McCrea, P; Shonukan, O | 1 |
Laurensse, E; Leyva, A; Peters, GJ; Pinedo, HM | 1 |
Kleeberg, UR; Mulder, JH; Rozencweig, M; Rümke, P; Thomas, D | 1 |
Kleeberg, UR; Voigt, H | 1 |
Erlichman, C; Vidgen, D | 1 |
Lankelma, J; Laurensse, E; Leyva, A; Peters, GJ; Pinedo, HM | 1 |
Chabner, BA; Donehower, RC; Erlichman, C; Klecker, R; Speyer, JL | 1 |
Appel, H; Lankelma, J; Leyva, A; Pinedo, HM; Smith, P | 1 |
Anderson, LW; Cysyk, RL; Erlichman, C; Karle, JM | 1 |
Boon, T; Brichard, V; Chen, Y; Engelhard, VH; Gulden, PH; Hendrickson, RC; Hunt, DF; Shabanowitz, J; Skipper, JC; Slingluff, CL; Van Pel, A; Wolfel, T | 1 |
Cleaveland, ES; Cooney, DA; Ford, H; Kelley, JA; Paull, K; Zaharevitz, DW | 1 |
Carothers, A; Haldane, F; Healy, E; Jackson, IJ; Rees, JL; Sikkink, S; Thody, AJ; Valverde, P | 1 |
Chidambaram, A; Fraser, MC; Goldstein, AM; Struewing, JP; Tucker, MA | 1 |
Pham, HT; Ruediger, R; Walter, G | 1 |
Baroni, A; D'Angelo, S; Galletti, P; Ingrosso, D; Lobianco, LL; Perfetto, B; Tufano, MA; Zappia, M | 1 |
Peng, ZY; Zhang, B | 1 |
Bowen, JM; Briscoe, WT; Griffin, AC; McBride, C | 1 |
Johnson, RK; Stark, GR; Swyryd, EA | 1 |
Goldin, A; Inouye, T; Johnson, RK; Stark, GR | 1 |
Green, LJ; Humphries, MJ; Komoriya, A; Mervic, M; Yamada, KM; Yamada, SS | 1 |
Hart, IR; Kalebic, T; McMillan, TJ; Stark, GR | 1 |
Cillo, C; Dick, JE; Hill, RP; Ling, V | 1 |
Chang, M; Creagan, ET; Cullinan, SA; Ebbert, L; Mailliard, JA; Morton, RF; Veeder, MH | 1 |
Chan, TC; Howell, SB; King, ME; Taetle, R; Young, B | 1 |
Gottschalk, A; Hoffer, PB | 1 |
Freeman, A; Holland, JF; Ohnuma, T; Sinks, LF | 1 |
Hempel, K; Männl, HF | 1 |
1 review(s) available for aspartic acid and Malignant Melanoma
Article | Year |
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Tumor scanning agents.
Topics: Antibodies, Neoplasm; Aspartic Acid; Bismuth; Bleomycin; Carbon Radioisotopes; Carcinoembryonic Antigen; Carcinoma, Hepatocellular; Cobalt Radioisotopes; Gallium; Hodgkin Disease; Humans; Indium; Iodine Radioisotopes; Liver Neoplasms; Lymphoma; Mediastinal Neoplasms; Melanoma; Methionine; Neoplasms; Radionuclide Imaging; Selenium; Serum Albumin; Tonsillar Neoplasms | 1974 |
1 trial(s) available for aspartic acid and Malignant Melanoma
Article | Year |
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Phase II studies of single-agent cimetidine and the combination N-phosphonacetyl-L-aspartate (NSC-224131) plus L-alanosine (NSC-153353) in advanced malignant melanoma.
Topics: Alanine; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cimetidine; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Melanoma; Middle Aged; Phosphonoacetic Acid; Pleural Neoplasms; Soft Tissue Neoplasms | 1987 |
35 other study(ies) available for aspartic acid and Malignant Melanoma
Article | Year |
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Discovery of an Amino Acid-Modified Near-Infrared Aza-BODIPY Photosensitizer as an Immune Initiator for Potent Photodynamic Therapy in Melanoma.
Topics: Amino Acids; Animals; Aspartic Acid; Boron Compounds; Cell Line, Tumor; Drug Discovery; Female; Humans; Immunotherapy; Melanoma; Mice; Mice, Inbred C57BL; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species; Structure-Activity Relationship; Subcellular Fractions; Xenograft Model Antitumor Assays | 2022 |
Topics: Aspartic Acid; Glutamic Acid; Humans; Isotopes; Melanoma; Zinc; Zinc Isotopes | 2022 |
Aspartate beta-hydroxylase domain containing 1 as a prognostic marker associated with immune infiltration in skin cutaneous melanoma.
Topics: Aspartic Acid; B7 Antigens; Humans; Melanoma; Melanoma, Cutaneous Malignant; Mixed Function Oxygenases; Prognosis; Skin Neoplasms; Transcription Factors; Tumor Microenvironment | 2023 |
Targeting the Warburg effect via LDHA inhibition engages ATF4 signaling for cancer cell survival.
Topics: Activating Transcription Factor 4; Amino Acid Transport System ASC; Aspartic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glycolysis; Humans; L-Lactate Dehydrogenase; Mechanistic Target of Rapamycin Complex 1; Melanoma; Minor Histocompatibility Antigens; Neoplasm Proteins; Protein Serine-Threonine Kinases; Serine; Signal Transduction | 2018 |
Influence of functional variants Asp312Asn and Lys751Gln of Xeroderma Pigmentosum Group D (XPD) and Glutathione S-transferase Mu 1 (GSTM1) and Theta 1 (GSTT1) genes on cutaneous melanoma susceptibility and prognosis.
Topics: Aged; Asparagine; Aspartic Acid; Cell Survival; Disease-Free Survival; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glutamine; Glutathione Transferase; Humans; Lysine; Melanoma; Middle Aged; Prognosis; Proportional Hazards Models; Skin Neoplasms; Treatment Outcome; Xeroderma Pigmentosum | 2019 |
Functional characterization of six aspartate (D) recombinant mojastin mutants (r-Moj): A second aspartate amino acid carboxyl to the RGD in r-Moj-D_ peptides is not sufficient to induce apoptosis of SK-Mel-28 cells.
Topics: Amino Acid Motifs; Animals; Antineoplastic Agents; Apoptosis; Aspartic Acid; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disintegrins; Drug Design; Enzyme Repression; Humans; Integrin alpha Chains; Integrin alphaV; Melanoma; Mutant Proteins; Peptide Fragments; rac1 GTP-Binding Protein; Recombinant Proteins; Reptilian Proteins; RNA Interference; Viper Venoms | 2016 |
Dual suppression of the cyclin-dependent kinase inhibitors CDKN2C and CDKN1A in human melanoma.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Benzamides; Blotting, Western; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p18; Cyclin-Dependent Kinase Inhibitor p21; Flow Cytometry; Gene Expression Regulation, Neoplastic; Genes, ras; Glutamic Acid; Glycine; Humans; MAP Kinase Signaling System; Melanocytes; Melanoma; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-jun; RNA, Small Interfering; Transcription Factor AP-1; Transfection; Transplantation, Heterologous; Valine; Viral Vaccines | 2012 |
Critical residues in the PMEL/Pmel17 N-terminus direct the hierarchical assembly of melanosomal fibrils.
Topics: Amino Acid Sequence; Amyloid; Aspartic Acid; Binding Sites; Blotting, Western; Cell Line, Tumor; gp100 Melanoma Antigen; Humans; Melanins; Melanoma; Melanosomes; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Organelles; Proline; Protein Transport; Proteolysis; Sequence Homology, Amino Acid; Tryptophan | 2013 |
Phase I trial of adoptive immunotherapy with cytolytic T lymphocytes immunized against a tyrosinase epitope.
Topics: Asparagine; Aspartic Acid; Clinical Trials, Phase I as Topic; Codon; Deamination; Epitopes, T-Lymphocyte; Humans; Immunotherapy, Adoptive; Melanoma; Monophenol Monooxygenase; Neoplasm Proteins; Protein Processing, Post-Translational; Sequence Analysis, DNA; T-Lymphocytes; Transplantation, Autologous | 2002 |
Melanoma cell CD44 interaction with the alpha 1(IV)1263-1277 region from basement membrane collagen is modulated by ligand glycosylation.
Topics: Amino Acids; Aspartic Acid; Binding Sites; Carbazoles; Cell Adhesion; Chondroitin Sulfate Proteoglycans; Chromatography, High Pressure Liquid; Circular Dichroism; Collagen Type IV; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glycosaminoglycans; Glycosylation; Humans; Hyaluronan Receptors; Hydroxylysine; Ligands; Lysine; Melanoma; Peptide Biosynthesis; Precipitin Tests; Protein Binding; Sodium Chloride; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Temperature; Tumor Cells, Cultured | 2003 |
Neurotrophin-induced melanoma cell migration is mediated through the actin-bundling protein fascin.
Topics: Actins; Amino Acid Substitution; Aspartic Acid; Carrier Proteins; Cell Movement; Cytoskeleton; Humans; Melanoma; Microfilament Proteins; Nerve Growth Factors; Phosphorylation; Protein Precursors; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Serine; Substrate Specificity; Tumor Cells, Cultured; Two-Hybrid System Techniques | 2003 |
Fluctuations in phosphoribosyl pyrophosphate levels in monolayer tumor cell lines. Effects of drugs.
Topics: Animals; Aspartic Acid; Buffers; Cell Line; Cytological Techniques; Fibroblasts; Humans; Melanoma; Methotrexate; Mice; Pentosephosphates; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate; Purine Nucleosides; Trypsin | 1984 |
N-(phosphonacetyl)-L-aspartate (PALA) in advanced malignant melanoma: a phase II trial of the EORTC Malignant Melanoma Cooperative Group.
Topics: Adult; Aged; Antineoplastic Agents; Aspartic Acid; Drug Eruptions; Drug Evaluation; Female; Humans; Male; Melanoma; Middle Aged; Organophosphorus Compounds; Phosphonoacetic Acid; Soft Tissue Neoplasms | 1982 |
PALA, vindesine, and cisplatin combination chemotherapy in advanced malignant melanoma. A pilot study.
Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Bone Marrow; Cisplatin; Drug Eruptions; Female; Humans; Male; Melanoma; Middle Aged; Nausea; Neoplasm Metastasis; Phosphonoacetic Acid; Pilot Projects; Vinblastine; Vindesine; Vomiting | 1984 |
Antitumor activity of N-phosphonacetyl-L-aspartic acid in combination with nitrobenzylthioinosine.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cell Line; Dose-Response Relationship, Drug; Female; Inosine; Melanoma; Mice; Mice, Inbred C57BL; Nucleosides; Organophosphorus Compounds; Phosphonoacetic Acid; Thioinosine; Thionucleotides | 1984 |
Separation of several 5-fluorouracil metabolites in various melanoma cell lines. Evidence for the synthesis of 5-fluorouracil-nucleotide sugars.
Topics: Animals; Aspartic Acid; Cell Line; Cells, Cultured; Chromatography; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Fluorouracil; Humans; Melanoma; Mice; Phosphonoacetic Acid; RNA, Neoplasm; Uracil Nucleotides; Uridine; Uridine Triphosphate | 1984 |
Phase I-phase II trial of N-phosphonacetyl-L-aspartic acid given by intravenous infusion and 5-fluorouracil given by bolus injection.
Topics: Adult; Aged; Antineoplastic Agents; Aspartic Acid; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Melanoma; Middle Aged; Neoplasms; Organophosphorus Compounds; Ovarian Neoplasms; Pancreatic Neoplasms; Phosphonoacetic Acid; Sarcoma | 1982 |
Inhibition of cell growth by N-(phosphonacetyl)-L-aspartate in human and murine cells in vitro.
Topics: Animals; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Cell Division; Cell Line; Humans; Leukemia; Melanoma; Mice; Neoplasms; Organophosphorus Compounds; Phosphonoacetic Acid | 1981 |
Serum uridine levels in patients receiving N-(phosphonacetyl)-L-aspartate.
Topics: Antimetabolites, Antineoplastic; Aspartic Acid; Colonic Neoplasms; Drug Evaluation; Humans; Melanoma; Organophosphorus Compounds; Phosphonoacetic Acid; Uridine | 1980 |
An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins.
Topics: Amino Acid Sequence; Antigens, Neoplasm; Asparagine; Aspartic Acid; Clone Cells; Epitopes; HLA-A2 Antigen; Humans; Melanoma; Membrane Proteins; Models, Biological; Molecular Sequence Data; Monophenol Monooxygenase; Peptide Fragments; Protein Processing, Post-Translational; Tumor Cells, Cultured | 1996 |
Identification of a novel inhibitor (NSC 665564) of dihydroorotate dehydrogenase with a potency equivalent to brequinar.
Topics: Antineoplastic Agents; Aspartic Acid; Biphenyl Compounds; Breast Neoplasms; Carbolines; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Colonic Neoplasms; Dihydroorotate Dehydrogenase; Enzyme Inhibitors; Female; Humans; Kidney Neoplasms; Kinetics; Leukemia; Lung Neoplasms; Male; Melanoma; Mitochondria; Orotic Acid; Ovarian Neoplasms; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Prostatic Neoplasms; Ribonucleotides; Sodium Bicarbonate; Software; Tumor Cells, Cultured | 1996 |
The Asp84Glu variant of the melanocortin 1 receptor (MC1R) is associated with melanoma.
Topics: Alleles; Aspartic Acid; Gene Frequency; Genetic Predisposition to Disease; Humans; Melanoma; Point Mutation; Receptors, Pituitary Hormone | 1996 |
Genotype-phenotype relationships in U.S. melanoma-prone families with CDKN2A and CDK4 mutations.
Topics: Adolescent; Adult; Age Factors; Aged; Arginine; Aspartic Acid; Cyclin-Dependent Kinases; Cysteine; Genes, p16; Genotype; Germ-Line Mutation; Glycine; Haplotypes; Humans; Melanoma; Middle Aged; Nevus; Pancreatic Neoplasms; Phenotype; Skin Neoplasms; Statistics, Nonparametric; Tryptophan; United States; Valine | 2000 |
Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Breast Neoplasms; Female; Glutamic Acid; Glycine; Humans; Lung Neoplasms; Melanoma; Molecular Sequence Data; Neoplasms; Peptide Fragments; Phosphoprotein Phosphatases; Point Mutation; Protein Binding; Protein Phosphatase 2; Protein Structure, Secondary; Tryptophan | 2001 |
UVA irradiation induces L-isoaspartyl formation in melanoma cell proteins.
Topics: Animals; Aspartic Acid; DNA Damage; DNA Fragmentation; DNA, Neoplasm; Humans; Melanoma; Neoplasm Proteins; Nitric Oxide; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Rats; Reactive Oxygen Species; Tumor Cells, Cultured; Ultraviolet Rays | 2001 |
Structural consequences of tumor-derived mutations in p16INK4a probed by limited proteolysis.
Topics: Ankyrin Repeat; Aspartic Acid; Circular Dichroism; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinases; Endopeptidase K; Humans; Hydrolysis; Leucine; Melanoma; Mutation; Peptide Fragments; Proline; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Structure-Activity Relationship; Valine | 2002 |
The distribution and properties of aspartyl transfer RNA in human and animal tumors.
Topics: Adenocarcinoma; Animals; Aspartic Acid; Carcinoma; Carcinoma, Ehrlich Tumor; Cells, Cultured; Cricetinae; Female; Genetic Code; Humans; Male; Melanoma; Mice; Neoplasms; Neoplasms, Experimental; Rats; Ribosomes; RNA, Neoplasm; RNA, Transfer; Sarcoma; Simian virus 40 | 1975 |
Effects of N-(phosphonacetyl)-L-aspartate on murine tumors and normal tissues in vivo and in vitro and the relationship of sensitivity to rate of proliferation and level of aspartate transcarbamylase.
Topics: Animals; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Cells, Cultured; Cyclophosphamide; Drug Evaluation, Preclinical; Glioma; Graft Rejection; Leukemia, Experimental; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid | 1978 |
Antitumor activity of N-(phosphonacetyl)-L-aspartic acid, a transition-state inhibitor of aspartate transcarbamylase.
Topics: Animals; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamyl Phosphate; Drug Administration Schedule; Female; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Male; Melanoma; Mice; Neoplasms, Experimental; Organophosphorus Compounds; Osteosarcoma; Phosphonoacetic Acid | 1976 |
The minimal essential sequence for a major cell type-specific adhesion site (CS1) within the alternatively spliced type III connecting segment domain of fibronectin is leucine-aspartic acid-valine.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Cattle; Cell Adhesion; Chickens; Fibronectins; Humans; Leucine; Melanoma; Mice; Molecular Sequence Data; Molecular Weight; Rats; RNA Splicing; Sequence Homology, Nucleic Acid; Tumor Cells, Cultured; Valine | 1991 |
High frequency of double drug resistance in the B16 melanoma cell line.
Topics: Amides; Animals; Antineoplastic Agents; Aspartic Acid; Cell Line; Colony-Forming Units Assay; Drug Resistance; Drug Synergism; Gene Amplification; Melanoma; Methotrexate; Mice; Ouabain; Phosphonoacetic Acid; Pyrazoles; Ribonucleosides; Ribose | 1990 |
Generation of drug-resistant variants in metastatic B16 mouse melanoma cell lines.
Topics: Animals; Aspartic Acid; Cell Line; Drug Resistance; Gene Amplification; Mathematics; Melanoma; Methotrexate; Mice; Neoplasm Metastasis; Organophosphorus Compounds; Phenotype; Phosphonoacetic Acid | 1987 |
Modulation of the activity of PALA by dipyridamole.
Topics: Animals; Aspartic Acid; Biological Transport; Cell Line; Colonic Neoplasms; Dipyridamole; Drug Interactions; Humans; In Vitro Techniques; Lethal Dose 50; Leukemia, Myeloid; Melanoma; Mice; Mice, Nude; Organophosphorus Compounds; Phosphonoacetic Acid; Pyrimidine Nucleosides; Tritium; Uridine | 1985 |
Biochemical and pharmacological studies with asparaginase in man.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Child; Colonic Neoplasms; Escherichia coli; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Melanoma; Metabolic Clearance Rate; Middle Aged; Multiple Myeloma; Neoplasms; Neuroblastoma; Osteosarcoma | 1970 |
The conversion of [3H]tyrosine to [3H]DOPA in mouse melanoma in vivo.
Topics: Animals; Asparagine; Aspartic Acid; Chromatography, Paper; Dihydroxyphenylalanine; Electrophoresis; Glutamates; Glutamine; Melanoma; Mice; Neoplasms, Experimental; Tyrosine | 1966 |