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aspartic acid and Lyme Disease

aspartic acid has been researched along with Lyme Disease in 2 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Lyme Disease: An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. The disease was formerly known as Lyme arthritis and first discovered at Old Lyme, Connecticut.

Research Excerpts

ExcerptRelevanceReference
"MurAs (enolpyruvyl-UDP-GlcNAc synthases) from pathogenic bacteria such as Borrelia burgdorferi (Lyme disease) and tuberculosis are fosfomycin resistant because an Asp-for-Cys substitution prevents them from being alkylated by this epoxide antibiotic."7.77Lyme disease enolpyruvyl-UDP-GlcNAc synthase: fosfomycin-resistant MurA from Borrelia burgdorferi, a fosfomycin-sensitive mutant, and the catalytic role of the active site Asp. ( Attia, M; Berti, PJ; Gilpin, ME; Jiang, S; Ting, YL, 2011)
"MurAs (enolpyruvyl-UDP-GlcNAc synthases) from pathogenic bacteria such as Borrelia burgdorferi (Lyme disease) and tuberculosis are fosfomycin resistant because an Asp-for-Cys substitution prevents them from being alkylated by this epoxide antibiotic."3.77Lyme disease enolpyruvyl-UDP-GlcNAc synthase: fosfomycin-resistant MurA from Borrelia burgdorferi, a fosfomycin-sensitive mutant, and the catalytic role of the active site Asp. ( Attia, M; Berti, PJ; Gilpin, ME; Jiang, S; Ting, YL, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jiang, S1
Gilpin, ME1
Attia, M1
Ting, YL1
Berti, PJ1
Eicken, C1
Sharma, V1
Klabunde, T1
Owens, RT1
Pikas, DS1
Höök, M1
Sacchettini, JC1

Other Studies

2 other studies available for aspartic acid and Lyme Disease

ArticleYear
Lyme disease enolpyruvyl-UDP-GlcNAc synthase: fosfomycin-resistant MurA from Borrelia burgdorferi, a fosfomycin-sensitive mutant, and the catalytic role of the active site Asp.
    Biochemistry, 2011, Mar-29, Volume: 50, Issue:12

    Topics: Alkyl and Aryl Transferases; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Biocatalys

2011
Crystal structure of Lyme disease antigen outer surface protein C from Borrelia burgdorferi.
    The Journal of biological chemistry, 2001, Mar-30, Volume: 276, Issue:13

    Topics: Amino Acid Sequence; Animals; Antigens, Bacterial; Aspartic Acid; Bacterial Outer Membrane Proteins;

2001