aspartic acid has been researched along with Liver Neoplasms in 59 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report a new syndrome of ascites, hyperbilirubinemia, and hypoalbuminemia after treatment with N-phosphonacetyl-L-aspartate (PALA) and fluorouracil for metastatic colorectal cancer." | 9.07 | A new syndrome: ascites, hyperbilirubinemia, and hypoalbuminemia after biochemical modulation of fluorouracil with N-phosphonacetyl-L-aspartate (PALA) ( Costa, P; Kemeny, N; Kurtz, RC; Martin, D; Murray, M; Niedzwiecki, D; Seiter, K; Urmacher, C, 1991) |
| "The treatment of metastatic colorectal cancer by chemotherapy alone was considered palliative and without the potential to cure patients unless patients were rendered resectable." | 5.33 | Continued survival of more than ten years, without resection of metastatic disease, in patients with metastatic colorectal cancer treated with biomodulated fluorouracil: report of two cases. ( Kemeny, NE; Leonard, GD, 2006) |
| "To report a new syndrome of ascites, hyperbilirubinemia, and hypoalbuminemia after treatment with N-phosphonacetyl-L-aspartate (PALA) and fluorouracil for metastatic colorectal cancer." | 5.07 | A new syndrome: ascites, hyperbilirubinemia, and hypoalbuminemia after biochemical modulation of fluorouracil with N-phosphonacetyl-L-aspartate (PALA) ( Costa, P; Kemeny, N; Kurtz, RC; Martin, D; Murray, M; Niedzwiecki, D; Seiter, K; Urmacher, C, 1991) |
| "Molybdenum dioxide-gadolinium-arginine/glycine/aspartic acid (MoS₂-Gd-RGD) sequences targeting nano-contrast agents that specifically bind to human hepatocellular carcinoma (HCC) HepG₂ cells were synthesized, and their targeting imaging effects on HCC cells and models were evaluated." | 4.02 | Molybdenum Dioxide (MoS₂)/Gadolinium (Gd) Containing Arginine-Glycine-Aspartic Acid (RGD) Sequences as New Nano-Contrast Agent for Cancer Magnetic Resonance Imaging (MRI). ( Hao, X; Li, W, 2021) |
| " In this work, novel rodlike supramolecular nanoassemblies (CNC @CB[8] @ PGEA) of degradable poly(aspartic acid) (PAsp) derivatives-grafted cellulose nanocrystals (CNCs) and hydroxyl-rich polycations (ethanolamine-functionalized poly(glycidyl methacrylate), PGEA) are proposed via typical cucurbit[8]uril (CB[8])-based host-guest interactions for delivery of different ncRNAs to treat hepatocellular carcinoma (HCC)." | 3.88 | Rodlike Supramolecular Nanoassemblies of Degradable Poly(Aspartic Acid) Derivatives and Hydroxyl-Rich Polycations for Effective Delivery of Versatile Tumor-Suppressive ncRNAs. ( Li, RQ; Liu, W; Pan, W; Song, HQ; Xu, FJ; Yang, M; Yu, B, 2018) |
| " Univariate analyses were conducted to determine the association among gender, age, hepatocellular carcinoma, hepatitis B e antigen-positive status, HBV-DNA level and tyrosine-methionine-aspartate-aspartate (YMDD) mutations on HBV recurrence in these patients." | 3.80 | Clinical-pathological analysis of hepatitis B virus recurrence after liver transplantation in Chinese patients. ( Gao, YJ; Jin, B; Li, HW; Liu, ZW; Ma, XM; Meng, FP; Su, HB; Zhang, M; Zhao, JM, 2014) |
| "Hereditary hemochromatosis is the most frequent hereditary metabolic disorder, with lethal outcome without treatment." | 2.42 | [Iron storage disease]. ( Dávid, K; Horváth, G, 2004) |
| "Liver metastases from breast cancer are associated with a poor prognosis, however, local control with microwave thermocoagulation therapy has been used in certain subgroups of these patients in the past decade." | 1.33 | Open-configuration MR-guided microwave thermocoagulation therapy for metastatic liver tumors from breast cancer. ( Abe, H; Endo, Y; Hanasawa, K; Kurumi, Y; Morikawa, S; Naitoh, H; Naka, S; Shiomi, H; Tani, T; Umeda, T, 2005) |
| "The treatment of metastatic colorectal cancer by chemotherapy alone was considered palliative and without the potential to cure patients unless patients were rendered resectable." | 1.33 | Continued survival of more than ten years, without resection of metastatic disease, in patients with metastatic colorectal cancer treated with biomodulated fluorouracil: report of two cases. ( Kemeny, NE; Leonard, GD, 2006) |
| "Twenty-one paired pharmacokinetic studies were completed on patients with colorectal, gastric, and hepatocellular cancer, utilizing positron emission tomography (PET), which allowed the acquisition of tumor, normal tissue, and plasma pharmacokinetic data and tumor blood flow (TBF) measurements." | 1.30 | Tumor, normal tissue, and plasma pharmacokinetic studies of fluorouracil biomodulation with N-phosphonacetyl-L-aspartate, folinic acid, and interferon alfa. ( Brady, F; Brown, G; Harte, RJ; Jones, T; Luthra, SJ; Matthews, JC; O'Reilly, SM; Osman, S; Price, PM; Tilsley, DW, 1999) |
| "In contrast, colorectal cancers with codon 12 aspartic acid substitutions accounted for most of the distant hematogenous deposits (P < 0." | 1.29 | Genotypic classification of colorectal adenocarcinoma. Biologic behavior correlates with K-ras-2 mutation type. ( Christensen, S; Finkelstein, SD; Sayegh, R; Swalsky, PA, 1993) |
| "Alanosine treatment results in the inhibition of cell division, DNA synthesis, RNA and protein synthesis (in this order), and a depletion of the cells of adenosine triphosphate." | 1.26 | Alanosine toxicity in Novikoff rat hepatoma cells due to inhibition of the conversion of inosine monophosphate to adenosine monophosphate. ( Graff, JC; Plagemann, PG, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (45.76) | 18.7374 |
| 1990's | 11 (18.64) | 18.2507 |
| 2000's | 4 (6.78) | 29.6817 |
| 2010's | 6 (10.17) | 24.3611 |
| 2020's | 11 (18.64) | 2.80 |
| Authors | Studies |
|---|---|
| Sheng, Y | 1 |
| Chen, Y | 1 |
| Zeng, Z | 1 |
| Wu, W | 1 |
| Wang, J | 1 |
| Ma, Y | 1 |
| Lin, Y | 1 |
| Zhang, J | 1 |
| Huang, Y | 1 |
| Li, W | 2 |
| Zhu, Q | 1 |
| Wei, X | 1 |
| Li, S | 1 |
| Wisanwattana, W | 1 |
| Li, F | 1 |
| Liu, W | 3 |
| Suksamrarn, A | 1 |
| Zhang, G | 1 |
| Jiao, W | 1 |
| Wang, F | 1 |
| Chen, M | 1 |
| Zhang, C | 1 |
| Du, X | 1 |
| Liu, X | 1 |
| Xing, B | 1 |
| Pinto, L | 1 |
| Balbi, E | 1 |
| Halpern, M | 1 |
| Carius, L | 1 |
| Roma, J | 1 |
| Cardoso, SW | 1 |
| Grinsztejn, B | 1 |
| Veloso, VG | 1 |
| Pacheco, L | 1 |
| Perazzo, H | 1 |
| Liu, F | 1 |
| Gai, X | 1 |
| Wu, Y | 1 |
| Zhang, B | 1 |
| Wu, X | 1 |
| Cheng, R | 1 |
| Tang, B | 1 |
| Shang, K | 1 |
| Zhao, N | 1 |
| Deng, W | 1 |
| Chen, J | 1 |
| Zhang, Z | 1 |
| Gu, S | 1 |
| Zheng, L | 1 |
| Zhang, H | 1 |
| De Falco, P | 1 |
| Lazzarino, G | 1 |
| Felice, F | 1 |
| Desideri, E | 1 |
| Castelli, S | 1 |
| Salvatori, I | 1 |
| Ciccarone, F | 1 |
| Ciriolo, MR | 1 |
| Wang, H | 1 |
| Liu, Y | 1 |
| Cui, J | 1 |
| Tong, M | 1 |
| Guan, W | 1 |
| Cao, Z | 1 |
| Gao, X | 1 |
| Han, X | 1 |
| Xian, X | 1 |
| Li, J | 1 |
| Zhao, L | 1 |
| Cheng, YT | 1 |
| Zhu, T | 1 |
| Ma, YZ | 1 |
| Ding, YZ | 1 |
| Meng, LQ | 1 |
| Xue, L | 1 |
| Ji, LX | 1 |
| Bittaye, SO | 1 |
| Kambi, A | 1 |
| Tekanyi, MAI | 1 |
| Tamba, S | 1 |
| Sanneh, L | 1 |
| Sisawo, MM | 1 |
| Jatta, A | 1 |
| Fatty, G | 1 |
| Jeng, A | 1 |
| Jallow, MS | 1 |
| Leigh, O | 1 |
| Njie, R | 1 |
| Wai-Sun Wong, V | 1 |
| Kao, JH | 1 |
| Li, ZC | 1 |
| Li, Z | 1 |
| Li, C | 1 |
| Fang, JC | 1 |
| Li, XZ | 1 |
| Zhao, YN | 1 |
| Liang, CY | 1 |
| Hao, X | 1 |
| Ma, H | 1 |
| Jiang, C | 1 |
| Song, HQ | 1 |
| Pan, W | 1 |
| Li, RQ | 1 |
| Yu, B | 1 |
| Yang, M | 1 |
| Xu, FJ | 1 |
| Infantino, V | 1 |
| Dituri, F | 1 |
| Convertini, P | 1 |
| Santarsiero, A | 1 |
| Palmieri, F | 1 |
| Todisco, S | 1 |
| Mancarella, S | 1 |
| Giannelli, G | 1 |
| Iacobazzi, V | 1 |
| Gao, YJ | 1 |
| Zhang, M | 1 |
| Jin, B | 1 |
| Meng, FP | 1 |
| Ma, XM | 1 |
| Liu, ZW | 1 |
| Su, HB | 1 |
| Zhao, JM | 1 |
| Li, HW | 1 |
| Darpolor, MM | 1 |
| Basu, SS | 1 |
| Worth, A | 1 |
| Nelson, DS | 1 |
| Clarke-Katzenberg, RH | 1 |
| Glickson, JD | 1 |
| Kaplan, DE | 1 |
| Blair, IA | 1 |
| Yamaguchi, Y | 1 |
| Yamamoto, K | 1 |
| Sato, Y | 1 |
| Inoue, S | 1 |
| Morinaga, T | 1 |
| Hirano, E | 1 |
| WAGLE, SR | 1 |
| MORRIS, HP | 3 |
| WEBER, G | 3 |
| RYAN, WL | 1 |
| LORINCZ, AB | 1 |
| SAHASRABUDHE, MB | 1 |
| APTE, BK | 1 |
| ABOOBAKER, VS | 1 |
| JAYARAMAN, R | 1 |
| Horváth, G | 1 |
| Dávid, K | 1 |
| Abe, H | 1 |
| Kurumi, Y | 1 |
| Naka, S | 1 |
| Shiomi, H | 1 |
| Umeda, T | 1 |
| Naitoh, H | 1 |
| Endo, Y | 1 |
| Hanasawa, K | 1 |
| Morikawa, S | 1 |
| Tani, T | 1 |
| Leonard, GD | 1 |
| Kemeny, NE | 1 |
| Kitteringham, NR | 1 |
| Palmer, L | 1 |
| Owen, A | 1 |
| Lian, LY | 1 |
| Jenkins, R | 1 |
| Dowdall, S | 1 |
| Gilmore, I | 1 |
| Park, BK | 1 |
| Goldring, CE | 1 |
| Yuan, TT | 1 |
| Faruqi, A | 1 |
| Shih, JW | 1 |
| Shih, C | 1 |
| Finkelstein, SD | 1 |
| Sayegh, R | 1 |
| Christensen, S | 1 |
| Swalsky, PA | 1 |
| Sviridov, D | 1 |
| Pyle, L | 1 |
| Fidge, N | 1 |
| Ragnhammar, P | 1 |
| Blomgren, H | 1 |
| Conner, EA | 1 |
| Wirth, PJ | 1 |
| Köhne, CH | 1 |
| Wilke, H | 1 |
| Schöffski, P | 1 |
| Schmoll, HJ | 1 |
| McGivan, JD | 1 |
| Harte, RJ | 1 |
| Matthews, JC | 1 |
| O'Reilly, SM | 1 |
| Tilsley, DW | 1 |
| Osman, S | 1 |
| Brown, G | 1 |
| Luthra, SJ | 1 |
| Brady, F | 1 |
| Jones, T | 1 |
| Price, PM | 1 |
| Mokotoff, M | 1 |
| Bagaglio, JF | 1 |
| Parikh, BS | 1 |
| Jackson, RC | 2 |
| Nakada, H | 1 |
| Funakoshi, I | 1 |
| Yamashina, I | 1 |
| Greenhouse, WV | 1 |
| Lehninger, AL | 1 |
| Graff, JC | 1 |
| Plagemann, PG | 2 |
| Clark, AW | 1 |
| Rudolph, FB | 1 |
| Keppler, DD | 1 |
| Okada, N | 1 |
| Shindo-Okada, N | 1 |
| Nishimura, S | 1 |
| Matsuno, T | 1 |
| Fowler, WC | 1 |
| Eisenberg, BL | 1 |
| Hoffman, JP | 1 |
| Kemeny, N | 1 |
| Seiter, K | 1 |
| Martin, D | 1 |
| Urmacher, C | 1 |
| Niedzwiecki, D | 1 |
| Kurtz, RC | 1 |
| Costa, P | 1 |
| Murray, M | 1 |
| Harley, EH | 1 |
| Sacks, S | 1 |
| Berman, P | 1 |
| Cohen, L | 2 |
| Simmonds, HA | 1 |
| Fairbanks, LD | 1 |
| Black, D | 1 |
| Hoffer, PB | 1 |
| Gottschalk, A | 1 |
| Cooney, DA | 1 |
| Yavelow, J | 1 |
| Zlotoff, R | 1 |
| Bergenstal, R | 1 |
| Burg, A | 1 |
| Morrison, R | 1 |
| Fleischman, R | 1 |
| Eagle, H | 1 |
| Washington, CL | 1 |
| Levy, M | 1 |
| Mayfield, ED | 1 |
| Lyman, K | 1 |
| Bresnick, E | 1 |
| Patterson, MK | 2 |
| Orr, GR | 2 |
| Eker, P | 1 |
| Fritzson, P | 1 |
| Spaeren, U | 1 |
| Efskind, J | 1 |
| Bhide, SV | 1 |
| Maley, F | 1 |
| Maley, GF | 1 |
| Chou, TC | 1 |
| Handschumacher, RE | 1 |
| Briscoe, WT | 1 |
| Taylor, W | 1 |
| Griffin, AC | 1 |
| Duff, R | 1 |
| Rapp, F | 1 |
| Tatibana, M | 1 |
| Shigesada, K | 1 |
| Rej, R | 1 |
| Fasce, CF | 1 |
| Vanderlinde, RE | 1 |
5 reviews available for aspartic acid and Liver Neoplasms
| Article | Year |
|---|---|
[Iron storage disease].
Topics: Aspartic Acid; Carcinoma, Hepatocellular; Chromosomes, Human, Pair 6; Cysteine; Diabetes Mellitus; D | 2004 |
How to optimize the effect of 5-fluorouracil modulated therapy in advanced colorectal cancer.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asp | 1995 |
The dead end of 5-fluorouracil double modulation and promise of continuous infusion schedules in the treatment of metastatic colorectal cancer.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Clin | 1996 |
Tumor scanning agents.
Topics: Antibodies, Neoplasm; Aspartic Acid; Bismuth; Bleomycin; Carbon Radioisotopes; Carcinoembryonic Anti | 1974 |
Two carbamyl phosphate synthetases of mammals: specific roles in control of pyrimidine and urea biosynthesis.
Topics: Adenosine Triphosphate; Animals; Arginine; Aspartic Acid; Carbamates; Carbon Isotopes; Carcinoma, He | 1972 |
1 trial available for aspartic acid and Liver Neoplasms
| Article | Year |
|---|---|
A new syndrome: ascites, hyperbilirubinemia, and hypoalbuminemia after biochemical modulation of fluorouracil with N-phosphonacetyl-L-aspartate (PALA)
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Aspartic Acid; Colorectal Neoplasms; | 1991 |
53 other studies available for aspartic acid and Liver Neoplasms
| Article | Year |
|---|---|
Identification of Pyruvate Carboxylase as the Cellular Target of Natural Bibenzyls with Potent Anticancer Activity against Hepatocellular Carcinoma via Metabolic Reprogramming.
Topics: Antineoplastic Agents; Bibenzyls; Carcinoma, Hepatocellular; Cell Proliferation; Click Chemistry; Ge | 2022 |
Long noncoding RNA LINC01234 promotes hepatocellular carcinoma progression through orchestrating aspartate metabolic reprogramming.
Topics: Animals; Argininosuccinate Synthase; Aspartic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Cel | 2022 |
Effectiveness of Direct-acting Agents After Liver Transplantation A Real-life Study in Rio de Janeiro.
Topics: Antiviral Agents; Aspartic Acid; Biomarkers; Brazil; Carcinoma, Hepatocellular; Female; Hepacivirus; | 2022 |
Oncogenic β-catenin stimulation of AKT2-CAD-mediated pyrimidine synthesis is targetable vulnerability in liver cancer.
Topics: Animals; Aspartic Acid; beta Catenin; Carcinogenesis; Dihydroorotase; Drug Delivery Systems; Ligases | 2022 |
Hindering NAT8L expression in hepatocellular carcinoma increases cytosolic aspartate delivery that fosters pentose phosphate pathway and purine biosynthesis promoting cell proliferation.
Topics: Acetyltransferases; Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Proliferation; Humans; L | 2023 |
Effects of Scutellaria strigillosa Hemsl. extract on HepG2 cell proliferation and apoptosis through binding to aspartate β-hydroxylase.
Topics: Apoptosis; Aspartic Acid; Carcinoma, Hepatocellular; Cell Proliferation; Hep G2 Cells; Humans; Liver | 2023 |
[Moxibustion with seed-size moxa cone enhances anti-tumor effect of cyclophosphamide on Hepa1-6 hepatoma-bearing mice by regulating apoptosis factor cysteine family].
Topics: Animals; Apoptosis; Aspartic Acid; Body Weight; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Cyc | 2023 |
Clinical manifestation, staging and prognosis of hepatocellular carcinoma in Gambian patients.
Topics: Abdominal Pain; Adult; Aspartic Acid; Carcinoma, Hepatocellular; Female; Gambia; Hepatitis B Surface | 2023 |
Letter: elevated aspartate aminotransferase and aspartate aminotransferase to alanine aminotransferase ratio predicts poor survival in hepatocellular carcinoma after resection-Authors' reply.
Topics: Alanine Transaminase; Asia, Eastern; Aspartate Aminotransferases; Aspartic Acid; Carcinoma, Hepatoce | 2020 |
Letter: elevated aspartate aminotransferase and aspartate aminotransferase to alanine aminotransferase ratio predicts poor survival in hepatocellular carcinoma after resection.
Topics: Alanine Transaminase; Asia, Eastern; Aspartate Aminotransferases; Aspartic Acid; Carcinoma, Hepatoce | 2020 |
Molybdenum Dioxide (MoS₂)/Gadolinium (Gd) Containing Arginine-Glycine-Aspartic Acid (RGD) Sequences as New Nano-Contrast Agent for Cancer Magnetic Resonance Imaging (MRI).
Topics: Animals; Arginine; Aspartic Acid; Carcinoma, Hepatocellular; Contrast Media; Gadolinium; Glycine; Li | 2021 |
Dehydroascorbic Acid and pGPMA Dual Modified pH-Sensitive Polymeric Micelles for Target Treatment of Liver Cancer.
Topics: Acrylamides; Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Dehydroascorbic Ac | 2018 |
Rodlike Supramolecular Nanoassemblies of Degradable Poly(Aspartic Acid) Derivatives and Hydroxyl-Rich Polycations for Effective Delivery of Versatile Tumor-Suppressive ncRNAs.
Topics: Aspartic Acid; Carcinoma, Hepatocellular; Gene Transfer Techniques; Genetic Vectors; Humans; Liver N | 2018 |
Epigenetic upregulation and functional role of the mitochondrial aspartate/glutamate carrier isoform 1 in hepatocellular carcinoma.
Topics: Amino Acid Transport Systems, Acidic; Antiporters; Aspartic Acid; Brain; Carcinoma, Hepatocellular; | 2019 |
Clinical-pathological analysis of hepatitis B virus recurrence after liver transplantation in Chinese patients.
Topics: Adult; Age Factors; Antiviral Agents; Aspartic Acid; Carcinoma, Hepatocellular; China; DNA, Viral; D | 2014 |
The aspartate metabolism pathway is differentiable in human hepatocellular carcinoma: transcriptomics and (13) C-isotope based metabolomics.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Aspartic Acid; Carbon Isotopes; Carcinoma, Hepatocellular; | 2014 |
Combination of aspartic acid and glutamic acid inhibits tumor cell proliferation.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; | 2016 |
COMPARATIVE BIOCHEMISTRY OF HEPATOMAS. V. STUDIES ON AMINO ACID INCORPORATION IN LIVER TUMORS OF DIFFERENT GROWTH RATES.
Topics: Alanine; Amino Acids; Aspartic Acid; Carcinoma, Hepatocellular; Glycine; Histocytochemistry; Isoleuc | 1963 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Gl | 1964 |
Partial deletion of aspartic acid from DNA-proteins during butter yellow carcinogenesis.
Topics: Aspartic Acid; Carcinogenesis; Carcinogens; DNA; Liver; Liver Neoplasms; Neoplasms; Nucleoproteins; | 1962 |
Open-configuration MR-guided microwave thermocoagulation therapy for metastatic liver tumors from breast cancer.
Topics: Adult; Aged; Alanine Transaminase; Aspartic Acid; Breast Neoplasms; Electrocoagulation; Female; Huma | 2005 |
Continued survival of more than ten years, without resection of metastatic disease, in patients with metastatic colorectal cancer treated with biomodulated fluorouracil: report of two cases.
Topics: Acetates; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colorectal Neoplasms; | 2006 |
Detection and biochemical characterisation of a novel polymorphism in the human GSTP1 gene.
Topics: Alleles; Amino Acid Substitution; Aspartic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Circul | 2007 |
The mechanism of natural occurrence of two closely linked HBV precore predominant mutations.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Calorimetry; Carcinoma, Hepatocellular; Cell Line | 1995 |
Genotypic classification of colorectal adenocarcinoma. Biologic behavior correlates with K-ras-2 mutation type.
Topics: Adenine; Adenocarcinoma; Aspartic Acid; Biology; Codon; Colonic Neoplasms; Gene Frequency; Genes, ra | 1993 |
Identification of a sequence of apolipoprotein A-I associated with the efflux of intracellular cholesterol to human serum and apolipoprotein A-I containing particles.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Apolipoprotein A-I; Arginine; Aspartic Acid; Binding Si | 1996 |
Protein alterations associated with gene amplification in cultured human and rodent cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carcinoma, Hepatocellular; Cell Division; CH | 1996 |
Rat hepatoma cells express novel transport systems for glutamine and glutamate in addition to those present in normal rat hepatocytes.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Biological Transport; Carrier Proteins; Ex | 1998 |
Tumor, normal tissue, and plasma pharmacokinetic studies of fluorouracil biomodulation with N-phosphonacetyl-L-aspartate, folinic acid, and interferon alfa.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Area Under Curve; Aspartic Acid; Co | 1999 |
Potential inhibitors of L-asparagine biosynthesis. 2. Chemistry and biological activity of beta-hydroxyaspartic acid and its derivatives.
Topics: Animals; Asparagine; Aspartic Acid; Carcinoma, Hepatocellular; Depression, Chemical; Glutamine; Hydr | 1975 |
Neoplastic transformation-linked alterations in adenylosuccinate synthetase activity.
Topics: Aging; Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Inosine N | 1975 |
The isolation and characterization of glycopeptides and mucopolysaccharides from plasma membranes of an ascites hepatoma, AH 130.
Topics: Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Membrane; Female; Glycopeptides; Glycosamino | 1975 |
Occurrence of the malate-aspartate shuttle in various tumor types.
Topics: Aminooxyacetic Acid; Animals; Antimycin A; Aspartic Acid; Carcinoma, Ehrlich Tumor; Carcinoma, Hepat | 1976 |
Alanosine toxicity in Novikoff rat hepatoma cells due to inhibition of the conversion of inosine monophosphate to adenosine monophosphate.
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Aspartic Acid; Carcinoma, Hepatoc | 1976 |
Regulation of purine metabolism. Adenylosuccinate synthetase from Novikoff ascites tumor cells.
Topics: Adenosine Monophosphate; Animals; Anti-Bacterial Agents; Aspartic Acid; Carcinoma, Hepatocellular; F | 1976 |
Aspartate carbamoyltransferase inhibition and uridylate trapping result in a synergistic depression of uridine triphosphate in hepatoma cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carcinoma, Hepatocellular; Cells, Cultured; | 1977 |
Isolation of mammalian tRNAAsp and tRNATyr by lectin-Sepharose affinity column chromatography.
Topics: Animals; Aspartic Acid; Carcinoma, Hepatocellular; Chromatography, Affinity; Concanavalin A; Liver; | 1977 |
Enzymes of the purine ribonucleotide cycle in rat hepatomas and kidney tumors.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; AMP Deaminase; Animals; Animals, Newborn; Antimetab | 1977 |
Oxidation of cytosolic NADH by the malate-aspartate shuttle in HuH13 human hepatoma cells.
Topics: Aspartic Acid; Carcinoma, Hepatocellular; Cytosol; Humans; Kinetics; Liver Neoplasms; Malates; NAD; | 1992 |
Hepatic resection following systemic chemotherapy for metastatic colorectal carcinoma.
Topics: Aged; Antineoplastic Agents; Aspartic Acid; Colorectal Neoplasms; Female; Fluorouracil; Hepatectomy; | 1992 |
Source and fate of circulating pyrimidines.
Topics: Aspartic Acid; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chromatography, High Pres | 1986 |
Azotomycin--toxicologic, biochemical and pharmacologic studies in mice.
Topics: Animals; Antibiotics, Antineoplastic; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Ataxia | 1974 |
The population-dependent requirement by cultured mammalian cells for metabolites which they can synthesize. II. Glutamic acid and glutamine; aspartic acid and asparagine.
Topics: Animals; Asparagine; Aspartic Acid; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Culture Techni | 1966 |
Incorporation of bicarbonate-14 C into pyrimidines and into ribonucleic acid of the Novikoff ascites tumor cell.
Topics: Ammonia; Animals; Aspartic Acid; Bicarbonates; Carcinoma, Hepatocellular; Chromatography, Ion Exchan | 1967 |
Asparagine biosynthesis by the Novikoff Hepatoma isolation, purification, property, and mechanism studies of the enzyme system.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Ammonium Chloride; Animals; Asparagine; Aspartic Acid; | 1968 |
Effect of dietary 2-acetylaminofluorene on rat liver enzymes involved in the anabolism and catabolism of nucleic acid precursors.
Topics: Animals; Aspartic Acid; Carcinogens; Diet; Female; Liver; Liver Neoplasms; N-Glycosyl Hydrolases; Nu | 1968 |
Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. I. Kinetics of incorporation of nucleosides into nucleotide pools and pool sizes during growth cycle.
Topics: Animals; Aspartic Acid; Biological Transport; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; | 1971 |
Comparative study of metabolic profiles of primary hepatoma, regenerating liver, and liver in newborn Swiss mice.
Topics: Acetates; Aldehyde-Lyases; Amides; Animals; Animals, Newborn; Aspartic Acid; Carbamates; Carcinoma, | 1971 |
The apparent induction of thymidylate synthetase by amethopterin.
Topics: Animals; Aspartic Acid; Benzoates; Carcinoma, Hepatocellular; Enzyme Induction; Folic Acid; Hepatect | 1971 |
Production of L-asparagine by tumor cells and the effect of asparagine analogs.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Aspartic Acid; Azo Compounds; Bromine; Carbon Isotop | 1972 |
Aspartyl transfer RNA profiles in normal and cancer cells.
Topics: Animals; Ascites; Aspartic Acid; Breast Neoplasms; Carbon Isotopes; Carcinoma, Hepatocellular; Cell | 1972 |
Increased aspartate aminotransferase activity of serum after in vitro supplementation with pyridoxal phosphate.
Topics: Adult; Aspartate Aminotransferases; Aspartic Acid; Carcinoma, Squamous Cell; Colorimetry; Cytoplasm; | 1973 |
Regeneration, tumor, dietary, and L-asparaginase effects on asparagine biosynthesis in rat liver.
Topics: Animals; Asparaginase; Asparagine; Aspartic Acid; Escherichia coli; Female; Ligases; Liver; Liver Ne | 1969 |