Page last updated: 2024-11-08

aspartic acid and Liver Diseases

aspartic acid has been researched along with Liver Diseases in 49 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Liver Diseases: Pathological processes of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"Liver necrosis was produced in rats by administering 3 doses of a mixture of carbon tetrachloride + olive oil, 2 ml/kg, ip."3.68Effect of aspartate and glutamate on carbon tetrachloride induced liver damage in rats. ( Garg, KN; Mehrotra, GC; Singh, J, 1990)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199038 (77.55)18.7374
1990's5 (10.20)18.2507
2000's2 (4.08)29.6817
2010's3 (6.12)24.3611
2020's1 (2.04)2.80

Authors

AuthorsStudies
Song, IA1
Jang, ES1
Oh, TK1
Zhang, CL1
Chen, MW1
Leng, W1
Liu, Y1
Shi, H1
Li, S1
Zhu, H1
Pi, D1
Hou, Y1
Gong, J1
Wang, X1
Zhang, A1
Han, Y1
Wang, P1
Sun, H1
Song, G1
Dong, T1
Yuan, Y1
Yuan, X1
Zhang, M1
Xie, N1
Zhang, H1
Dong, H1
Dong, W1
FODOR, O3
ABEL, C2
BAN, A1
MANASIA, M2
SANTAY, I2
BORDA, M1
ZANINI, P1
FACCHETTI, A1
CEDRANGOLO, F1
KAPLANSKII, BS1
WAKISAKA, G1
KONO, S1
SHIODA, M1
LABORIE, G1
KATSU, M1
OGAWA, J1
NAKAGAWA, H1
OSAKO, R1
ABE, T1
YAMAMOTO, I1
JUVANON, J1
ITO, N1
Ejilemele, AA1
Nwauche, CA1
Ejele, OA1
Furiosi, P1
Mercati, U1
Pasquini, F1
Powis, G1
Dudley, RE1
Klaassen, CD1
Ohta, Y1
Sasaki, E1
Nishida, K1
Kobayashi, T1
Nagata, M1
Ishiguro, I1
Schieber, A1
Brückner, H1
Rupp-Classen, M1
Specht, W1
Nowitzki-Grimm, S1
Classen, HG1
Shiono, Y1
Ikeda, R1
Hayashi, H1
Wakusawa, S1
Sanae, F1
Takikawa, T1
Imaizumi, Y1
Yano, M1
Yoshioka, K1
Kawanaka, M1
Yamada, G1
Henglein-Ottermann, D1
Kreis, R1
Ross, BD1
Farrow, NA1
Ackerman, Z1
Bosman, DK1
Deutz, NE1
Maas, MA1
van Eijk, HM1
Smit, JJ1
de Haan, JG1
Chamuleau, RA1
Singh, J1
Garg, KN1
Mehrotra, GC1
Watanabe, A1
Shiota, T1
Takei, N1
Nagashima, H1
Biron, P1
London, JW1
Yarrish, R1
Dzubow, LD1
Garfinkel, D1
Ripamonti, C1
Hunold, W1
Iencica, R1
Wotzka, R2
Weber, D2
Raab, W1
Cairella, M1
Volpari, B1
Nicrosini, F1
Szirmai, E1
Raab, WP1
Kleine, TO1
Chlond, H1
Melzer, H1
Heynen, U1
Szám, I1
Orlowski, M1
Szczeklik, A1
Narczewska, B1
Schäfer, W1
Sprinkle, T1
Greer, M1
Williams, CM1
Aschke, J1
Cachin, M1
Pergola, F1

Reviews

2 reviews available for aspartic acid and Liver Diseases

ArticleYear
Effect of human renal and hepatic disease on the pharmacokinetics of anticancer drugs.
    Cancer treatment reviews, 1982, Volume: 9, Issue:2

    Topics: Antineoplastic Agents; Aspartic Acid; Bleomycin; Cisplatin; Cyclophosphamide; Doxorubicin; Fluoroura

1982
[Angiotensinases of human plasma].
    Revue canadienne de biologie, 1967, Volume: 26, Issue:1

    Topics: Aminopeptidases; Angiotensin II; Asparagine; Aspartic Acid; Edetic Acid; Endopeptidases; Humans; Liv

1967

Trials

3 trials available for aspartic acid and Liver Diseases

ArticleYear
[Controlled clinical trial of a new substance with hepatotropic activity, carried out with an experimental cross-over plan in double-blind conditions].
    La Clinica terapeutica, 1972, Jul-15, Volume: 62, Issue:1

    Topics: Adult; Aged; Alcoholism; Amino Acids; Aspartic Acid; Chemical and Drug Induced Liver Injury; Chronic

1972
[Clinical experiences in liver diseases (specially in patients with fatty liver due to alcoholism and food poisoning) under monotherapy with ornithine aspartate].
    Zeitschrift fur Allgemeinmedizin, 1973, Apr-10, Volume: 49, Issue:10

    Topics: Adolescent; Adult; Alcoholism; Aspartic Acid; Clinical Trials as Topic; Dipeptides; Drug Tolerance;

1973
[On the therapy of liver diseases with ornithine aspartate].
    Medizinische Klinik, 1969, Volume: 64, Issue:35

    Topics: Acute Disease; Alanine Transaminase; Ammonia; Aspartic Acid; Bilirubin; Cholangitis; Chronic Disease

1969

Other Studies

44 other studies available for aspartic acid and Liver Diseases

ArticleYear
Validation of Dynamic Aspartate-to-Alanine Aminotransferase Ratio for Predicting Liver Disease Mortality.
    Hepatology communications, 2022, Volume: 6, Issue:4

    Topics: Adult; Alanine; Alanine Transaminase; Aspartate Aminotransferases; Aspartic Acid; Cohort Studies; D-

2022
[A case report of macro-AST presenting with long-term isolated elevated aspartate aminotransferase in adult].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2019, Apr-20, Volume: 27, Issue:4

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Aspartic Acid; Blood Chemical Analysis; Hu

2019
Aspartate alleviates liver injury and regulates mRNA expressions of TLR4 and NOD signaling-related genes in weaned pigs after lipopolysaccharide challenge.
    The Journal of nutritional biochemistry, 2014, Volume: 25, Issue:6

    Topics: Animals; Aspartic Acid; Biomarkers; China; Crosses, Genetic; Dietary Supplements; Disease Models, An

2014
Urine metabolomics analysis for biomarker discovery and detection of jaundice syndrome in patients with liver disease.
    Molecular & cellular proteomics : MCP, 2012, Volume: 11, Issue:8

    Topics: Adult; Alanine; Aspartic Acid; Biomarkers; Chromatography, High Pressure Liquid; Disease Progression

2012
[Protective effect of aspartic acid on experimental hepatic lesions].
    Revue internationale d'hepatologie, 1957, Volume: 7, Issue:8

    Topics: Aspartic Acid; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver Diseases

1957
[Therapeutic effect of aspartic acid in hepatic diseases].
    Revue internationale d'hepatologie, 1959, Volume: 9, Issue:2

    Topics: Aspartic Acid; Humans; Liver Diseases; Organic Chemicals

1959
[Research on the ammonium-binding action of aspartic acid in hepatic diseases].
    Revue internationale d'hepatologie, 1960, Volume: 10

    Topics: Ammonia; Ammonium Compounds; Aspartic Acid; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Liver D

1960
[The role of Mg and K aspartates in experimental liver regeneration].
    Archivio italiano di chirurgia, 1962, Volume: 88

    Topics: Aspartic Acid; Hepatectomy; Hyperplasia; Liver; Liver Diseases; Liver Regeneration; Magnesium; Potas

1962
[Ornithine and aspartic acid: catalizers of ureogenesis. Recent use in hepato-protective therapy].
    La Riforma medica, 1962, Dec-22, Volume: 76

    Topics: Aspartic Acid; Humans; Liver Diseases; Ornithine

1962
[ON THE RELATION BETWEEN THE CHANGES IN THE ACTIVITY OF GLUTAMIC-ASPARTATE AMINOPHERASE IN THE BLOOD AND MORPHOLOGICAL LESIONS OF THE LIVER PARENCHYMA IN DIFFERENT FORMS OF CHOLECYSTITIS].
    Khirurgiia, 1963, Volume: 39

    Topics: Aspartate Aminotransferases; Aspartic Acid; Blood Chemical Analysis; Cholecystectomy; Cholecystitis;

1963
[ASPARTATES].
    [Sogo rinsho] Clinic all-round, 1963, Volume: 12

    Topics: Aspartic Acid; Blood Chemical Analysis; Heart Diseases; Humans; Hypokalemia; Liver Diseases; Magnesi

1963
[STUDIES ON ASPARTATES. 1. CLINICAL STUDIES].
    [Sogo rinsho] Clinic all-round, 1963, Volume: 12

    Topics: Amino Acids; Aspartic Acid; Biomedical Research; Cardiovascular Diseases; Diabetes Mellitus; Humans;

1963
[APROPOS OF THE CLINICAL INDICATIONS OF A NEW DRINKABLE ENRICHED LIVER EXTRACT OF THE ANTITOXIC FRACTION].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1964, Volume: 141

    Topics: Alcoholic Intoxication; Alcoholism; Anemia; Aspartic Acid; Asthenia; Humans; Liver Cirrhosis; Liver

1964
[CLINICAL TRIAL OF POTASSIUM AND MAGNESIUM SALTS OF ASPARTIC ACID IN LIVER DISEASES].
    [Chiryo] [Therapy], 1964, Volume: 46

    Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Aspartic Acid; Geriatrics; Hepatitis;

1964
[CLINICAL TRIAL OF "LIVER ANTITOXIC FRACTION, LIVER EXTRACT-ASPARTATES-YEAST" IN GENERAL AND HEPATIC PATHOLOGY].
    Lyon medical, 1964, Apr-26, Volume: 211

    Topics: Aspartic Acid; Humans; Liver Diseases; Liver Extracts; Vitamin B 12; Vitamin B Complex; Yeast, Dried

1964
[CLINICO-PATHOLOGICAL STUDIES ON THE TREATMENT OF LIVER DISEASE BY ASPARTATE].
    Iryo, 1964, Volume: 18

    Topics: Aspartic Acid; Drug Therapy; Humans; Liver Diseases

1964
Pattern of abnormal liver enzymes in HIV patients presenting at a Nigerian Tertiary Hospital.
    The Nigerian postgraduate medical journal, 2007, Volume: 14, Issue:4

    Topics: Adolescent; Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartic Acid; Cohort Studies; Female

2007
[Recent acquisitions on the pathogenesis of hyperammoniemia: clinico-experimental study on a new anti-ammonia drug].
    Minerva medica, 1967, Feb-21, Volume: 58, Issue:15

    Topics: Ammonia; Animals; Arginine; Aspartic Acid; Dogs; Humans; Kidney Diseases; Liver Diseases

1967
Changes in hepatic glutathione concentration modify cadmium-induced hepatotoxicity.
    Toxicology and applied pharmacology, 1984, Mar-15, Volume: 72, Issue:3

    Topics: Alanine; Animals; Aspartic Acid; Cadmium Poisoning; Chemical and Drug Induced Liver Injury; Cysteine

1984
Preventive effect of dai-saiko-to (da-chai-hu-tang) extract on disrupted hepatic active oxygen metabolism in rats with carbon tetrachloride-induced liver injury.
    The American journal of Chinese medicine, 1995, Volume: 23, Issue:1

    Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartic Acid; Carbon Tetrachloride; Chemical a

1995
Evaluation of D-amino acid levels in rat by gas chromatography-selected ion monitoring mass spectrometry: no evidence for subacute toxicity of orally fed D-proline and D-aspartic acid.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Mar-28, Volume: 691, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Chemical and Drug Induced Liver Injury; Female

1997
C282Y and H63D mutations in the HFE gene have no effect on iron overload disorders in Japan.
    Internal medicine (Tokyo, Japan), 2001, Volume: 40, Issue:9

    Topics: Adult; Asian People; Aspartic Acid; Cysteine; Female; Hemochromatosis; Hemochromatosis Protein; Hepa

2001
[Influence of ornithine aspartate on the experimentally induced hyperammoniemia. Clinico-experimental study].
    Therapie der Gegenwart, 1976, Volume: 115, Issue:9

    Topics: Adult; Ammonia; Aspartic Acid; Humans; Liver Diseases; Ornithine

1976
Metabolic disorders of the brain in chronic hepatic encephalopathy detected with H-1 MR spectroscopy.
    Radiology, 1992, Volume: 182, Issue:1

    Topics: Aspartic Acid; Brain; Choline; Female; Glucose; Glutamates; Glutamic Acid; Glutamine; Hepatic Enceph

1992
Amino acid release from cerebral cortex in experimental acute liver failure, studied by in vivo cerebral cortex microdialysis.
    Journal of neurochemistry, 1992, Volume: 59, Issue:2

    Topics: Acute Disease; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Dialysis; gamma-Aminobutyric Ac

1992
Effect of aspartate and glutamate on carbon tetrachloride induced liver damage in rats.
    Indian journal of experimental biology, 1990, Volume: 28, Issue:12

    Topics: Animals; Aspartic Acid; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Glutamates; Li

1990
Excitatory and inhibitory amino acid neurotransmitters and ammonia metabolism in hepatic failure rats.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1985, Volume: 185, Issue:5

    Topics: Ammonia; Animals; Aspartic Acid; Brain; Carbon Tetrachloride Poisoning; gamma-Aminobutyric Acid; Glu

1985
Editorial: Towards an artificial liver.
    British medical journal, 1974, Sep-14, Volume: 3, Issue:5932

    Topics: Acetaminophen; Aspartic Acid; Brain Chemistry; Charcoal; Glutamates; Hepatic Encephalopathy; Hepatit

1974
Computer simulation and optimization, as exemplified by the enzyme-coupled aminotransferase (transaminase) assays.
    Clinical chemistry, 1974, Volume: 20, Issue:11

    Topics: Alanine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspartic Acid; Computers; Evalu

1974
[Effects of treatment with nucleotides and aspartic acid in chronic liver diseases].
    Medicina interna, 1972, Volume: 24, Issue:12

    Topics: Aspartic Acid; Bilirubin; Chronic Disease; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Nucle

1972
[Further clinical experiences with ornithine aspartate in liver diseases].
    Therapie der Gegenwart, 1972, Volume: 111, Issue:3

    Topics: Adult; Aspartic Acid; Fatty Liver; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Male;

1972
[Confirmation of a liver-protecting action of L-ornithine-L-aspartate using the experimental model of hypokalaemic liver damage].
    Wiener klinische Wochenschrift, 1972, May-26, Volume: 84, Issue:21

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspartic Acid; Hypokalemia; Liver; Liver

1972
[Betaine aspartate in the therapy of liver diseases].
    La Clinica terapeutica, 1972, Mar-31, Volume: 60, Issue:6

    Topics: Adult; Aged; Aspartic Acid; Betaine; Female; Humans; Lipid Metabolism; Liver Diseases; Liver Functio

1972
[Therapeutic activity of betaine aspartate].
    La Clinica terapeutica, 1972, May-15, Volume: 61, Issue:3

    Topics: Adult; Aspartic Acid; Betaine; Dyspepsia; Evaluation Studies as Topic; Humans; Liver Diseases; Middl

1972
[Our clinical experience with ornithine aspartate].
    Minerva medica, 1971, Jun-13, Volume: 62, Issue:47

    Topics: Adenosine Triphosphate; Aspartic Acid; Homocysteine; Humans; Lactones; Liver Diseases; Liver Functio

1971
Experimental liver damage in potassium depletion, inhibited by L-ornithine-L-aspartate.
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:10

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspartic Acid; Chemical and Drug Induced

1971
[On the enzymatic differential diagnosis of the involvement of various organs in Erb's progressive muscular dystrophy during three medications].
    Enzymologia biologica et clinica, 1969, Volume: 10, Issue:1

    Topics: Adolescent; Aspartic Acid; Brain; Child; Child, Preschool; Clinical Enzyme Tests; Diagnosis, Differe

1969
[Protection of the liver and liver therapy with Hepamerz].
    Zeitschrift fur Allgemeinmedizin, 1970, Jan-20, Volume: 46, Issue:2

    Topics: Animals; Aspartic Acid; Humans; Liver Diseases; Ornithine; Rats

1970
[Prevention and therapy of hepatic coma].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1970, Volume: 30, Issue:1

    Topics: Aged; Amides; Ammonia; Aspartic Acid; Chlorothiazide; Clopamide; Depression, Chemical; Diuretics; Fe

1970
Determination of aminopeptidase A activity in the serum.
    Archivum immunologiae et therapiae experimentalis, 1968, Volume: 16, Issue:6

    Topics: Aminopeptidases; Anilides; Aspartic Acid; Biliary Tract Diseases; Chromatography, Ion Exchange; Chro

1968
[Intravenous administration of ornithine aspartate to patients with hepatic diseases].
    Munchener medizinische Wochenschrift (1950), 1968, Oct-25, Volume: 110, Issue:43

    Topics: Ammonia; Aspartic Acid; Humans; Injections, Intravenous; Liver Diseases; Liver Function Tests; Ornit

1968
Detection of argininosuccinic aciduria by gas chromatography.
    Clinica chimica acta; international journal of clinical chemistry, 1969, Volume: 23, Issue:1

    Topics: Arginine; Aspartic Acid; Ataxia; Chemical Precipitation; Chromatography, Gas; Epilepsy; Esters; Huma

1969
[Experiences with ornithine-aspartate in liver diseases].
    Die Medizinische Welt, 1969, Mar-22, Volume: 12

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Child; Female; Hepatitis A; Humans; Liver Cirrhosis; Liver D

1969
[Betaine aspartate in the hepato-digestive domain].
    Semaine therapeutique, 1966, Volume: 42, Issue:8

    Topics: Aspartic Acid; Betaine; Dyspepsia; Fatty Liver; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases;

1966