Page last updated: 2024-11-08

aspartic acid and Liver Cirrhosis

aspartic acid has been researched along with Liver Cirrhosis in 48 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
"Enzymatic analysis of aspartate/alanine aminotransferase (AST/ALT) does not exactly represent the progression of liver fibrosis or inflammation."7.96Immunological measurement of aspartate/alanine aminotransferase in predicting liver fibrosis and inflammation. ( Baik, GH; Bang, CS; Choi, EY; Ham, YL; Kim, DJ; Kim, HJ; Kim, SY; Shin, SP; Suk, KT; Yang, YJ, 2020)
"Enzymatic analysis of aspartate/alanine aminotransferase (AST/ALT) does not exactly represent the progression of liver fibrosis or inflammation."3.96Immunological measurement of aspartate/alanine aminotransferase in predicting liver fibrosis and inflammation. ( Baik, GH; Bang, CS; Choi, EY; Ham, YL; Kim, DJ; Kim, HJ; Kim, SY; Shin, SP; Suk, KT; Yang, YJ, 2020)
"Asymmetric dimethylarginine (ADMA) is an inhibitor of nitric oxide synthase that accumulates in liver disease and may contribute to hepatic encephalopathy (HE)."3.79Asymmetric dimethylarginine is strongly associated with cognitive dysfunction and brain MR spectroscopic abnormalities in cirrhosis. ( Ahluwalia, V; Bajaj, JS; Bouneva, I; Fuchs, M; Gilles, H; Heuman, DM; Kraft, KA; Luketic, V; Monteith, P; Noble, NA; Puri, P; Sanyal, AJ; Sterling, RK; Stravitz, RT; Wade, JB; White, MB, 2013)
" This study investigates the reversing capacity of an adenosine derivative compound (IFC305) on a rat model of liver cirrhosis and gene expression changes associated with it."3.76An adenosine derivative compound, IFC305, reverses fibrosis and alters gene expression in a pre-established CCl(4)-induced rat cirrhosis. ( de Sánchez, VC; Hernández-Luis, F; Hernández-Muñoz, R; Loredo, ML; Martínez-Pérez, L; Pérez-Carreón, JI; Ramírez-Salcedo, J; Suárez-Cuenca, JA; Velasco-Loyden, G; Velázquez-Martínez, I; Vidrio-Gómez, S; Yañez-Maldonado, L, 2010)
" Among a number of clinical and laboratory variables analyzed, the only independent predictive factors of overt HE were hyponatremia (serum sodium < 130 mEq / l), history of overt HE, serum bilirubin,and serum creatinine."3.75Hyponatremia is a risk factor of hepatic encephalopathy in patients with cirrhosis: a prospective study with time-dependent analysis. ( Arroyo, V; Baccaro, ME; Ginès, P; Gómez-Ansón, B; Guevara, M; Martín-Llahí, M; Monté-Rubio, GC; Rami, L; Ríos, J; Torre, A; Torres, F, 2009)
" Decreased myo-inositol and increased glutamine levels were noted to be the most sensitive spectroscopic markers for cirrhotic patients with hepatic encephalopathy (HE)."3.70Proton magnetic resonance spectroscopy (1H-MRS) findings for the brain in patients with liver cirrhosis reflect the hepatic functional reserve. ( Kim, ST; Lee, JH; Lee, YS; Lim, TH; Min, YI; Mun, CW; Seo, DW; Suh, DJ, 1999)
"Hereditary hemochromatosis is the most frequent hereditary metabolic disorder, with lethal outcome without treatment."2.42[Iron storage disease]. ( Dávid, K; Horváth, G, 2004)
"The enhanced liver fibrosis (ELF) index is a highly sensitive noninvasive marker of hepatic fibrosis that has had limited assessment in the HIV/HCV population."1.62The Enhanced Liver Fibrosis Index Predicts Hepatic Fibrosis Superior to FIB4 and APRI in HIV/HCV Infected Patients. ( Abdel-Hameed, EA; Kottilil, S; Rouster, SD; Sherman, KE, 2021)
"The prevalence of hepatotoxicity, liver fibrosis, and CKD were 7."1.51Evaluation of hepatic and kidney dysfunction among newly diagnosed HIV patients with viral hepatitis infection in Cape Coast, Ghana. ( Anabire, NG; Annan, I; Aryee, PA; Eliason, S; Hagan, OCK; Helegbe, GK; Luuse, AT; Obiri-Yaboah, D; Tetteh, WJ, 2019)
"Patients who have liver cirrhosis are at increased risk of bacterial infections, such as bacteremia, meningitis, pneumonia, urinary tract infections, and spontaneous bacterial peritonitis, due to immunodeficiency associated with the severity of the cirrhosis."1.34Brain abscess in adult cirrhotic patients: two case reports. ( Chen, IY; Chung, CL; Howng, SL; Kwan, AL; Lieu, AS, 2007)
"Minimal hepatic encephalopathy (MHE) is frequently diagnosed in patients with liver cirrhosis who do not show overt clinical cirrhosis-associated neurological deficits."1.33Chemical shift magnetic resonance spectroscopy of cingulate grey matter in patients with minimal hepatic encephalopathy. ( Graziadei, IW; Hinterhuber, H; Kugener, A; Marksteiner, J; Mattedi, M; Mechtcheriakov, S; Schocke, M; Vogel, W, 2005)
"The metabolic syndrome was present in 23 (27%), hepatic steatosis in 43 (50%), steatohepatitis in 18 (21%) and significant fibrosis in 38 (44%)."1.33The effect of the metabolic syndrome, hepatic steatosis and steatohepatitis on liver fibrosis in hereditary hemochromatosis. ( Abraham, SC; Adams, LA; Angulo, P; Brandhagen, D; Torgerson, H, 2006)
"Hepatic encephalopathy is a common problem in cirrhosis."1.30Cerebral abnormalities in patients with cirrhosis detected by proton magnetic resonance spectroscopy and magnetic resonance imaging. ( Andus, T; Feuerbach, S; Fründ, R; Geissler, A; Held, P; Hollerbach, S; Holstege, A; Lock, G; Schölmerich, J, 1997)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199020 (41.67)18.7374
1990's4 (8.33)18.2507
2000's6 (12.50)29.6817
2010's8 (16.67)24.3611
2020's10 (20.83)2.80

Authors

AuthorsStudies
Jain, A1
Sharma, BC1
Mahajan, B1
Srivastava, S1
Kumar, A1
Sachdeva, S1
Sonika, U1
Dalal, A1
Ridola, L1
Nardelli, S1
Gioia, S1
Faccioli, J1
Riggio, O1
Madian, A1
Eliwa, A1
Abdalla, H1
A Azeem Aly, H1
Kitsugi, K1
Noritake, H1
Matsumoto, M1
Hanaoka, T1
Umemura, M1
Yamashita, M1
Takatori, S1
Ito, J1
Ohta, K1
Chida, T1
Ulmasov, B1
Neuschwander-Tetri, BA1
Suda, T1
Kawata, K1
Pinto, L1
Balbi, E1
Halpern, M1
Carius, L1
Roma, J1
Cardoso, SW1
Grinsztejn, B1
Veloso, VG1
Pacheco, L1
Perazzo, H1
Sung, PS1
Abdel-Hameed, EA1
Rouster, SD1
Kottilil, S1
Sherman, KE1
Gunda, DW1
Mtui, EF1
Manyiri, PM1
Majinge, DC1
Kilonzo, SB1
Mazigo, HD1
Kidenya, BR1
Ding, Y1
Lin, H1
Chen, X1
Zhu, B1
Xu, X2
Shen, W1
Gao, M1
He, N1
Kim, HJ1
Kim, SY1
Shin, SP1
Yang, YJ1
Bang, CS1
Baik, GH1
Kim, DJ1
Ham, YL1
Choi, EY1
Suk, KT1
Anabire, NG1
Tetteh, WJ1
Obiri-Yaboah, D1
Annan, I1
Luuse, AT1
Aryee, PA1
Helegbe, GK1
Hagan, OCK1
Eliason, S1
Rollet-Kurhajec, KC1
Moodie, EE1
Walmsley, S1
Cooper, C1
Pick, N1
Klein, MB1
Meng, LP1
Chen, YC1
Li, YH1
Zhu, JS1
Ye, JL1
Guevara, M1
Baccaro, ME1
Torre, A1
Gómez-Ansón, B1
Ríos, J1
Torres, F1
Rami, L1
Monté-Rubio, GC1
Martín-Llahí, M1
Arroyo, V1
Ginès, P1
Pérez-Carreón, JI1
Martínez-Pérez, L1
Loredo, ML1
Yañez-Maldonado, L1
Velasco-Loyden, G1
Vidrio-Gómez, S1
Ramírez-Salcedo, J1
Hernández-Luis, F1
Velázquez-Martínez, I1
Suárez-Cuenca, JA1
Hernández-Muñoz, R1
de Sánchez, VC1
Castera, L1
Pinzani, M1
Garcia-Martinez, R1
Rovira, A1
Alonso, J1
Jacas, C1
Simón-Talero, M1
Chavarria, L1
Vargas, V1
Córdoba, J1
Ferraioli, G1
Tinelli, C1
Malfitano, A1
Dal Bello, B1
Filice, G1
Filice, C1
Above, E1
Barbarini, G1
Brunetti, E1
Calderon, W1
Di Gregorio, M1
Lissandrin, R1
Ludovisi, S1
Maiocchi, L1
Michelone, G1
Mondelli, M1
Patruno, SF1
Perretti, A1
Poma, G1
Sacchi, P1
Zaramella, M1
Zicchetti, M1
Bajaj, JS1
Ahluwalia, V1
Wade, JB1
Sanyal, AJ1
White, MB1
Noble, NA1
Monteith, P1
Fuchs, M1
Sterling, RK1
Luketic, V1
Bouneva, I1
Stravitz, RT1
Puri, P1
Kraft, KA1
Gilles, H1
Heuman, DM1
FODOR, O2
BORDA, M1
MANASIA, M1
SANTAY, I1
LABORIE, G1
KATSU, M1
OGAWA, J1
NAKAGAWA, H1
OSAKO, R1
ABE, T1
YAMAMOTO, I1
FAGE, P1
KNAUFF, HG1
SEYBOLD, D1
KANTERS, A1
Shindo, M1
Hamada, K1
Nishioji, K1
Muramatsu, A1
Oda, Y1
Okuno, T1
Horváth, G1
Dávid, K1
Mechtcheriakov, S1
Schocke, M1
Kugener, A1
Graziadei, IW1
Mattedi, M1
Hinterhuber, H1
Vogel, W1
Marksteiner, J1
Adams, LA1
Angulo, P1
Abraham, SC1
Torgerson, H1
Brandhagen, D1
Chung, CL1
Lieu, AS1
Chen, IY1
Kwan, AL1
Howng, SL1
De Luca, FM1
Tuveri, A1
Geissler, A1
Lock, G1
Fründ, R1
Held, P1
Hollerbach, S1
Andus, T1
Schölmerich, J1
Feuerbach, S1
Holstege, A1
Iwamoto, H1
Sakai, H1
Kotoh, K1
Nakamuta, M1
Nawata, H1
Lee, JH1
Seo, DW1
Lee, YS1
Kim, ST1
Mun, CW1
Lim, TH1
Min, YI1
Suh, DJ1
Schmidt, W1
Wolf, G1
Grüngreiff, K1
Meier, M1
Reum, T1
Lavoie, J1
Giguère, JF1
Layrargues, GP1
Butterworth, RF1
Van Leuven, F1
Weyne, J1
Iencica, R1
Busuttil, A1
Alston, WC1
Horne, CH1
MacSween, RN1
Leonhardt, H1
Wotzka, R2
Weber, D2
Melzer, H1
Szám, I1
Müting, D1
Popescu, S1
Grigoraş, D1
Barbarino, F1
Aschke, J1
Gumucio, JJ1
Laughrey, EG1
Henley, KS1
Kosozu, K1
Cachin, M1
Pergola, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Role of Magnetic Resonance Imaging in Detection of Minimal Hepatic Encephalopathy[NCT04131205]40 participants (Anticipated)Observational2019-06-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aspartic acid and Liver Cirrhosis

ArticleYear
[Iron storage disease].
    Orvosi hetilap, 2004, Sep-26, Volume: 145, Issue:39

    Topics: Aspartic Acid; Carcinoma, Hepatocellular; Chromosomes, Human, Pair 6; Cysteine; Diabetes Mellitus; D

2004

Trials

2 trials available for aspartic acid and Liver Cirrhosis

ArticleYear
L-ornithine L-aspartate in acute treatment of severe hepatic encephalopathy: A double-blind randomized controlled trial.
    Hepatology (Baltimore, Md.), 2022, Volume: 75, Issue:5

    Topics: Ammonia; Aspartic Acid; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Ornithine; Rifax

2022
[On the therapy of liver diseases with ornithine aspartate].
    Medizinische Klinik, 1969, Volume: 64, Issue:35

    Topics: Acute Disease; Alanine Transaminase; Ammonia; Aspartic Acid; Bilirubin; Cholangitis; Chronic Disease

1969

Other Studies

45 other studies available for aspartic acid and Liver Cirrhosis

ArticleYear
Letter to the editor: Episodic-precipitant-induced hepatic encephalopathy treatment: Look at new and old precipitants!
    Hepatology (Baltimore, Md.), 2022, Volume: 75, Issue:4

    Topics: Aspartic Acid; Double-Blind Method; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Ornithine

2022
Aspartate transferase-to-platelet ratio index-plus: A new simplified model for predicting the risk of mortality among patients with COVID-19.
    World journal of gastroenterology, 2022, Apr-28, Volume: 28, Issue:16

    Topics: Adult; Aspartate Aminotransferases; Aspartic Acid; Biomarkers; Blood Platelets; Cohort Studies; COVI

2022
Arg-Gly-Asp-binding integrins activate hepatic stellate cells via the hippo signaling pathway.
    Cellular signalling, 2022, Volume: 99

    Topics: Arginine; Aspartic Acid; Focal Adhesion Protein-Tyrosine Kinases; Glycine; Hepatic Stellate Cells; H

2022
Effectiveness of Direct-acting Agents After Liver Transplantation A Real-life Study in Rio de Janeiro.
    Archives of medical research, 2022, Volume: 53, Issue:6

    Topics: Antiviral Agents; Aspartic Acid; Biomarkers; Brazil; Carcinoma, Hepatocellular; Female; Hepacivirus;

2022
A different detection method reveals a new role of alanine aminotransferase as an indicator of liver fibrosis.
    The Korean journal of internal medicine, 2020, Volume: 35, Issue:2

    Topics: Alanine; Alanine Transaminase; Aspartate Aminotransferases; Aspartic Acid; Humans; Inflammation; Liv

2020
The Enhanced Liver Fibrosis Index Predicts Hepatic Fibrosis Superior to FIB4 and APRI in HIV/HCV Infected Patients.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 08-02, Volume: 73, Issue:3

    Topics: Aspartate Aminotransferases; Aspartic Acid; Biomarkers; Hepacivirus; Hepatitis C; Hepatitis C, Chron

2021
Schistosoma mansoni-related periportal fibrosis; can we use APRI and PSDR levels in the real-time selection of patients for targeted endoscopy in a resource-limited setting? A case-control study.
    BMC gastroenterology, 2021, May-13, Volume: 21, Issue:1

    Topics: Animals; Aspartic Acid; Case-Control Studies; Cross-Sectional Studies; Endoscopy; Esophageal and Gas

2021
Comprehensive metabolomics profiling reveals common metabolic alterations underlying the four major non-communicable diseases in treated HIV infection.
    EBioMedicine, 2021, Volume: 71

    Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Atherosclerosis; Cognitive Dysfunction; Female; Glu

2021
Immunological measurement of aspartate/alanine aminotransferase in predicting liver fibrosis and inflammation.
    The Korean journal of internal medicine, 2020, Volume: 35, Issue:2

    Topics: Alanine; Alanine Transaminase; Aspartate Aminotransferases; Aspartic Acid; Biomarkers; Biopsy; Hepat

2020
Evaluation of hepatic and kidney dysfunction among newly diagnosed HIV patients with viral hepatitis infection in Cape Coast, Ghana.
    BMC research notes, 2019, Jul-31, Volume: 12, Issue:1

    Topics: Adult; Alanine Transaminase; Aspartic Acid; Blood Platelets; Coinfection; Cross-Sectional Studies; F

2019
Hepatic Fibrosis Progression in HIV-Hepatitis C Virus Co-Infection--The Effect of Sex on Risk of Significant Fibrosis Measured by Aspartate-to-Platelet Ratio Index.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Adult; Antiretroviral Therapy, Highly Active; Aspartate Aminotransferases; Aspartic Acid; Biomarkers

2015
Viability assessment of magnetic resonance spectroscopy for the detection of minimal hepatic encephalopathy severity.
    European journal of radiology, 2015, Volume: 84, Issue:10

    Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Cognition; Creatine; Female; Glutamic Acid; Glutamine; G

2015
Hyponatremia is a risk factor of hepatic encephalopathy in patients with cirrhosis: a prospective study with time-dependent analysis.
    The American journal of gastroenterology, 2009, Volume: 104, Issue:6

    Topics: Adult; Aged; Aspartic Acid; Bilirubin; Brain Chemistry; Creatine; Creatinine; Female; Follow-Up Stud

2009
An adenosine derivative compound, IFC305, reverses fibrosis and alters gene expression in a pre-established CCl(4)-induced rat cirrhosis.
    The international journal of biochemistry & cell biology, 2010, Volume: 42, Issue:2

    Topics: Adenosine; Animals; Aspartic Acid; Carbon Tetrachloride; Gene Expression Profiling; Gene Expression

2010
Non-invasive assessment of liver fibrosis: are we ready?
    Lancet (London, England), 2010, Apr-24, Volume: 375, Issue:9724

    Topics: Aspartic Acid; Biomarkers; Elasticity Imaging Techniques; Humans; Liver Cirrhosis; Platelet Count

2010
Hepatic encephalopathy is associated with posttransplant cognitive function and brain volume.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2011, Volume: 17, Issue:1

    Topics: Adult; Aspartic Acid; Atrophy; Brain; Chi-Square Distribution; Cognition; Cognition Disorders; Femal

2011
Performance of real-time strain elastography, transient elastography, and aspartate-to-platelet ratio index in the assessment of fibrosis in chronic hepatitis C.
    AJR. American journal of roentgenology, 2012, Volume: 199, Issue:1

    Topics: Adult; Area Under Curve; Aspartic Acid; Biopsy; Blood Platelets; Disease Progression; Elasticity Ima

2012
Asymmetric dimethylarginine is strongly associated with cognitive dysfunction and brain MR spectroscopic abnormalities in cirrhosis.
    Journal of hepatology, 2013, Volume: 58, Issue:1

    Topics: Adult; Arginine; Aspartic Acid; Biomarkers; Brain; Cognition Disorders; Cross-Sectional Studies; Fem

2013
[Research on the ammonium-binding action of aspartic acid in hepatic diseases].
    Revue internationale d'hepatologie, 1960, Volume: 10

    Topics: Ammonia; Ammonium Compounds; Aspartic Acid; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Liver D

1960
[APROPOS OF THE CLINICAL INDICATIONS OF A NEW DRINKABLE ENRICHED LIVER EXTRACT OF THE ANTITOXIC FRACTION].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1964, Volume: 141

    Topics: Alcoholic Intoxication; Alcoholism; Anemia; Aspartic Acid; Asthenia; Humans; Liver Cirrhosis; Liver

1964
[CLINICAL TRIAL OF POTASSIUM AND MAGNESIUM SALTS OF ASPARTIC ACID IN LIVER DISEASES].
    [Chiryo] [Therapy], 1964, Volume: 46

    Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Aspartic Acid; Geriatrics; Hepatitis;

1964
[CLINICAL TRIALS OF A DRUG COMBINATION GROUPING THE ANTITOXIC FRACTIONS OF THE LIVER WITH ASPARTATES AND EXTRACTS OF THE LIVER WITH YEASTS].
    Toulouse medical, 1964, Volume: 65

    Topics: Arteritis; Aspartic Acid; Drug Combinations; Geriatrics; Hernia, Diaphragmatic; Hernia, Hiatal; Huma

1964
[FREE PLASMA AMINO ACIDS AND BLOOD AMMONIA FOLLOWING ORAL PROTEIN LOAD. STUDIES IN NORMAL PERSONS AND PATIENTS WITH LIVER CIRRHOSIS].
    Klinische Wochenschrift, 1965, Apr-01, Volume: 43

    Topics: Amino Acids; Ammonia; Arginine; Aspartic Acid; Blood; Dietary Proteins; Glutamates; Humans; Liver Ci

1965
The predictive value of liver fibrosis in determining the effectiveness of interferon and lamivudine therapies for chronic hepatitis B.
    Journal of gastroenterology, 2004, Volume: 39, Issue:3

    Topics: Adult; Alanine Transaminase; Antiviral Agents; Aspartic Acid; DNA, Viral; Drug Resistance, Viral; Fe

2004
Chemical shift magnetic resonance spectroscopy of cingulate grey matter in patients with minimal hepatic encephalopathy.
    Neuroradiology, 2005, Volume: 47, Issue:1

    Topics: Aspartic Acid; Cerebral Cortex; Choline; Creatinine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli

2005
The effect of the metabolic syndrome, hepatic steatosis and steatohepatitis on liver fibrosis in hereditary hemochromatosis.
    Liver international : official journal of the International Association for the Study of the Liver, 2006, Volume: 26, Issue:3

    Topics: Adult; Aged; Aspartic Acid; Cysteine; Fatty Liver; Female; Genetic Predisposition to Disease; Glucos

2006
Brain abscess in adult cirrhotic patients: two case reports.
    The Kaohsiung journal of medical sciences, 2007, Volume: 23, Issue:1

    Topics: Aged; Aspartic Acid; Brain Abscess; Choline; Creatine; Humans; Liver Cirrhosis; Magnetic Resonance I

2007
[Changes induced by intravenous administration of potassium salts in the electrocardiogram and in urinary excretion and plasmatic and erythrocytic levels of sodium and potassium].
    Atti della Accademia dei fisiocritici in Siena. Sezione medico-fisica, 1966, Volume: 15, Issue:2

    Topics: Adult; Aged; Aspartic Acid; Chlorides; Diuresis; Electrocardiography; Electrolytes; Female; Glucose;

1966
Cerebral abnormalities in patients with cirrhosis detected by proton magnetic resonance spectroscopy and magnetic resonance imaging.
    Hepatology (Baltimore, Md.), 1997, Volume: 25, Issue:1

    Topics: Adult; Aged; Aspartic Acid; Brain; Choline; Female; Glutamic Acid; Hepatic Encephalopathy; Humans; I

1997
Soluble Arg-Gly-Asp peptides reduce collagen accumulation in cultured rat hepatic stellate cells.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:5

    Topics: Animals; Arginine; Aspartic Acid; Cell Adhesion; Cells, Cultured; Collagen; Collagenases; Extracellu

1999
Proton magnetic resonance spectroscopy (1H-MRS) findings for the brain in patients with liver cirrhosis reflect the hepatic functional reserve.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:8

    Topics: Adult; Aged; Aspartic Acid; Basal Ganglia; Brain; Choline; Creatinine; Energy Metabolism; Female; Gl

1999
Hepatic encephalopathy influences high-affinity uptake of transmitter glutamate and aspartate into the hippocampal formation.
    Metabolic brain disease, 1990, Volume: 5, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Ammonia; Animals; Aspartic Acid; Female; Glutamates; Glutamic Acid;

1990
Amino acid changes in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy.
    Journal of neurochemistry, 1987, Volume: 49, Issue:3

    Topics: Aged; Amino Acids; Aspartic Acid; Brain Chemistry; Chromatography, High Pressure Liquid; Female; gam

1987
Proceedings: Ammonia and amino acids in the brain of the rat with chronic hepatic failure.
    Archives internationales de physiologie et de biochimie, 1974, Volume: 82, Issue:4

    Topics: Amino Acids; Ammonia; Animals; Aspartic Acid; Brain; Carbon Tetrachloride Poisoning; Chronic Disease

1974
[Effects of treatment with nucleotides and aspartic acid in chronic liver diseases].
    Medicina interna, 1972, Volume: 24, Issue:12

    Topics: Aspartic Acid; Bilirubin; Chronic Disease; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Nucle

1972
Effect of the production of experimental cirrhosis in rats on serum aminotransferase levels.
    Revue europeenne d'etudes cliniques et biologiques. European journal of clinical and biological research, 1972, Volume: 17, Issue:10

    Topics: Alanine; Animals; Aspartic Acid; Carbon Tetrachloride; Drug Synergism; Kinetics; Liver Cirrhosis; Ph

1972
[Pathogenesis and therapy of exogenous hepatic coma].
    Fortschritte der Medizin, 1973, Jan-11, Volume: 91, Issue:1

    Topics: Amino Acids; Aspartic Acid; Brain; Dipeptides; Electroencephalography; Hepatic Encephalopathy; Human

1973
[Further clinical experiences with ornithine aspartate in liver diseases].
    Therapie der Gegenwart, 1972, Volume: 111, Issue:3

    Topics: Adult; Aspartic Acid; Fatty Liver; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Male;

1972
[Prevention and therapy of hepatic coma].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1970, Volume: 30, Issue:1

    Topics: Aged; Amides; Ammonia; Aspartic Acid; Chlorothiazide; Clopamide; Depression, Chemical; Diuretics; Fe

1970
[Treatment of hepatic cirrhosis and hepatic coma with drugs having the capacity of lowering the blood ammonia levels].
    La Clinica terapeutica, 1967, Aug-31, Volume: 42, Issue:4

    Topics: Ammonia; Arginine; Aspartic Acid; Bacteria; Female; Glutamates; Hepatic Encephalopathy; Humans; Live

1967
[Treatment with aspartic acid in hepatic coma caused by hyperammonemia].
    Medicina interna, 1968, Volume: 20, Issue:7

    Topics: Ammonia; Aspartic Acid; Hepatic Encephalopathy; Humans; Liver Cirrhosis

1968
[Experiences with ornithine-aspartate in liver diseases].
    Die Medizinische Welt, 1969, Mar-22, Volume: 12

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Child; Female; Hepatitis A; Humans; Liver Cirrhosis; Liver D

1969
Effect of hypokalemia on the reductive amination of alpha-ketoglutarate by mitochondria from normal and cirrhotic rat liver.
    Gastroenterology, 1969, Volume: 56, Issue:4

    Topics: Ammonia; Animals; Aspartic Acid; Glutamate Dehydrogenase; Glutamates; Hypokalemia; Ketoglutaric Acid

1969
[Clinical study on the effects of L-ornithine-L-aspartate on liver dysfunction].
    Iryo, 1966, Volume: 20, Issue:4

    Topics: Aspartic Acid; Hepatitis; Hepatitis B; Humans; Liver Cirrhosis; Ornithine

1966
[Betaine aspartate in the hepato-digestive domain].
    Semaine therapeutique, 1966, Volume: 42, Issue:8

    Topics: Aspartic Acid; Betaine; Dyspepsia; Fatty Liver; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases;

1966