aspartic acid has been researched along with Li-Fraumeni Syndrome in 3 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Li-Fraumeni Syndrome: Rare autosomal dominant syndrome characterized by mesenchymal and epithelial neoplasms at multiple sites. MUTATION of the p53 tumor suppressor gene, a component of the DNA DAMAGE response pathway, apparently predisposes family members who inherit it to develop certain cancers. The spectrum of cancers in the syndrome was shown to include, in addition to BREAST CANCER and soft tissue sarcomas (SARCOMA); BRAIN TUMORS; OSTEOSARCOMA; LEUKEMIA; and ADRENOCORTICAL CARCINOMA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tlsty, TD | 2 |
| White, A | 2 |
| Livanos, E | 2 |
| Sage, M | 1 |
| Roelofs, H | 1 |
| Briot, A | 1 |
| Poulose, B | 1 |
| Livingstone, LR | 1 |
| Sprouse, J | 1 |
| Jacks, T | 1 |
| Yin, Y | 1 |
| Tainsky, MA | 1 |
| Bischoff, FZ | 1 |
| Strong, LC | 1 |
| Wahl, GM | 1 |
1 review available for aspartic acid and Li-Fraumeni Syndrome
| Article | Year |
|---|---|
Genomic integrity and the genetics of cancer.
Topics: Adenovirus E1A Proteins; Adenoviruses, Human; Antimetabolites; Apoptosis; Aspartic Acid; Cell Cycle; | 1994 |
2 other studies available for aspartic acid and Li-Fraumeni Syndrome
| Article | Year |
|---|---|
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Base Sequence; Carbamoyl-Phosphate Synthase | 1992 |
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.
Topics: Aspartic Acid; Base Sequence; Cell Cycle; Chromosome Deletion; Fibroblasts; G1 Phase; Gene Amplifica | 1992 |