aspartic acid has been researched along with Leukodystrophy, Globoid Cell in 4 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Leukodystrophy, Globoid Cell: An autosomal recessive metabolic disorder caused by a deficiency of GALACTOSYLCERAMIDASE leading to intralysosomal accumulation of galactolipids such as GALACTOSYLCERAMIDES and PSYCHOSINE. It is characterized by demyelination associated with large multinucleated globoid cells, predominantly involving the white matter of the central nervous system. The loss of MYELIN disrupts normal conduction of nerve impulses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Krabbe disease (globoid cell leukodystrophy [GLD]) is an autosomal recessive lysosomal disorder affecting the central and peripheral nervous system." | 2.71 | Proton MRS profile of cerebral metabolic abnormalities in Krabbe disease. ( Brockmann, K; Dechent, P; Frahm, J; Hanefeld, F; Rusch, O; Wilken, B, 2003) |
| "We present a case of infantile onset Krabbe disease with prolonged survival, initial intracranial optic nerves and optic chiasm hypertrophy, and serial changes on cranial magnetic resonance imaging and magnetic resonance spectroscopy." | 1.38 | Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease. ( Bunge, M; Mhanni, AA; Ryner, L; Salman, MS; Udow, S, 2012) |
| "Adult-onset Krabbe disease is an uncommon form of leukodystrophy." | 1.34 | The earliest MR imaging and proton MR spectroscopy abnormalities in adult-onset Krabbe disease. ( Månsson, JE; Melberg, A; Raininko, R; Wang, C; Weis, J, 2007) |
| "Two twins with late infantile globoid cell leukodystrophy of Krabbe's disease were studied with conventional magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy." | 1.31 | Magnetic resonance spectroscopy and magnetic resonance imaging findings in Krabbe's disease. ( Anthony, DC; Astrakas, LG; Darras, BT; Poussaint, TY; Tzika, AA; Zarifi, MK, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Udow, S | 1 |
| Bunge, M | 1 |
| Ryner, L | 1 |
| Mhanni, AA | 1 |
| Salman, MS | 1 |
| Brockmann, K | 1 |
| Dechent, P | 1 |
| Wilken, B | 1 |
| Rusch, O | 1 |
| Frahm, J | 1 |
| Hanefeld, F | 1 |
| Wang, C | 1 |
| Melberg, A | 1 |
| Weis, J | 1 |
| Månsson, JE | 1 |
| Raininko, R | 1 |
| Zarifi, MK | 1 |
| Tzika, AA | 1 |
| Astrakas, LG | 1 |
| Poussaint, TY | 1 |
| Anthony, DC | 1 |
| Darras, BT | 1 |
1 trial available for aspartic acid and Leukodystrophy, Globoid Cell
| Article | Year |
|---|---|
Proton MRS profile of cerebral metabolic abnormalities in Krabbe disease.
Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Child; Child, Preschool; Choline; Creatinine; Dipeptides | 2003 |
3 other studies available for aspartic acid and Leukodystrophy, Globoid Cell
| Article | Year |
|---|---|
Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease.
Topics: Anticonvulsants; Aspartic Acid; Brain Chemistry; Choline; Combined Modality Therapy; Creatine; DNA M | 2012 |
The earliest MR imaging and proton MR spectroscopy abnormalities in adult-onset Krabbe disease.
Topics: Adult; Age Factors; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Leukodystrophy, Globoid | 2007 |
Magnetic resonance spectroscopy and magnetic resonance imaging findings in Krabbe's disease.
Topics: Aspartic Acid; Brain; Choline; Humans; Infant; Leukodystrophy, Globoid Cell; Magnetic Resonance Imag | 2001 |