aspartic acid has been researched along with Leukemia L 1210 in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (81.82) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CUTTS, JH | 1 |
| GREENBERG, NH; MEAD, JA; SCHRECKER, AW; SEEGER, DR; TOMCUFCIK, AS | 1 |
| Cordi, A; Hervé, G; Lequeux, T; Masson, S; Pfund, E; Pierre, A; Serre, V; Vazeux, M | 1 |
| Cadman, E; Grant, S; Jakubowski, A; Rauscher, F | 1 |
| Anderson, LW; Cysyk, RL; Karle, JM | 1 |
| Anderson, LW; Cysyk, RL; Monks, A; Strong, J | 1 |
| Cadman, E; Goldberg, D; Heimer, R | 1 |
| Handschumacher, RE; Levy, EJ; Moyer, JD; Smith, PA | 1 |
| Kufe, DW; Loh, E | 1 |
| Duś, D; Mastalerz, P; Salwa, J | 1 |
| Grindey, GB; Kinahan, JJ; Kowal, EP | 1 |
| Durrani, FA; Rustum, YM; van Laar, JA | 1 |
| Cory, AH; Cory, JG | 1 |
| Greenhouse, WV; Lehninger, AL | 1 |
| Handschumacher, RE; Moyer, JD | 1 |
| Goldin, A; Inouye, T; Johnson, RK; Stark, GR | 1 |
| Donsback, RC; Sirotnak, FM | 1 |
| Doré, JF; Goetsch, L; Hamedi-Sangsari, F; Malley, S; Navarro, C; Thomasset, N; Tournaire, R; Vila, J | 1 |
| Martin, DS; Sawyer, RC; Stolfi, RL | 1 |
| Donsbach, RC; Sirotnak, FM | 1 |
| Bloch, A; Robins, MJ; Robins, RK; Shuman, DA | 1 |
| Braun, LL; Layton, RM | 1 |
22 other study(ies) available for aspartic acid and Leukemia L 1210
| Article | Year |
|---|---|
EFFECTS OF OTHER AGENTS ON THE BIOLOGIC RESPONSES TO VINCALEUKOBLASTINE.
Topics: 2-Aminopurine; Aminopterin; Animals; Aspartic Acid; Azaguanine; Biological Products; Colchicine; Cortisone; Glutamates; Leukemia; Leukemia L1210; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Pharmacology; Purines; Research; Tryptophan; Vinblastine | 1964 |
THE PHARMACOLOGICAL AND BIOCHEMICAL ACTIVITY OF 4-AMINO-4-DEOXY-10-METHYLPTEROYLASPARTIC ACID.
Topics: Adenine; Amino Acids; Animals; Aspartic Acid; Enzyme Inhibitors; Folic Acid; Formates; Kinetics; Leukemia L1210; Liver; Methotrexate; Mice; Oxidoreductases; Pharmacology; Research | 1965 |
Efficient synthesis of fluorothiosparfosic acid analogues with potential antitumoral activity.
Topics: Animals; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Leukemia L1210; Phosphonoacetic Acid; Thioacetamide | 2005 |
Effect of N-(phosphonacetyl)-L-aspartate on 5-azacytidine metabolism in P388 and L1210 cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Azacitidine; Cell Division; Cytidine; DNA, Neoplasm; Leukemia L1210; Leukemia, Experimental; Mice; Neoplasm Proteins; Organophosphorus Compounds; Phosphonoacetic Acid; RNA, Neoplasm; Uridine | 1981 |
Effect of plasma concentrations of uridine on pyrimidine biosynthesis in cultured L1210 cells.
Topics: Animals; Aspartic Acid; Bicarbonates; Culture Media; Leukemia L1210; Mice; Phosphonoacetic Acid; Pyrimidines; Sodium Bicarbonate; Uracil Nucleotides; Uridine | 1984 |
Flux through the de novo pyrimidine pathway in vivo. Effect of N-phosphonacetyl-L-aspartate, a potent inhibitor of aspartate transcarbamylase.
Topics: Animals; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Carbon Dioxide; Kinetics; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Organophosphorus Compounds; Oxygen; Phosphonoacetic Acid; Pyrimidines | 1983 |
Modulation of fluoropyrimidine metabolism in L1210 cells by L-alanosine.
Topics: Adenine; Alanine; Animals; Aspartic Acid; Cells, Cultured; Clone Cells; Deoxyuridine; Leukemia L1210; Mice; Nucleotides; Pyrimidines; Time Factors | 1983 |
Kinetics of N-(phosphonacetyl)-L-aspartate and pyrazofurin depletion of pyrimidine ribonucleotide and deoxyribonucleotide pools and their relationship to nucleic acid synthesis in intact and permeabilized cells.
Topics: Amides; Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Deoxyribonucleotides; DNA Replication; DNA, Neoplasm; Kinetics; Leukemia L1210; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Pyrazoles; Pyrimidine Nucleotides; Ribonucleosides; Ribonucleotides; Ribose; RNA, Neoplasm; Transcription, Genetic | 1982 |
Synergistic effects with inhibitors of de novo pyrimidine synthesis, acivicin, and N-(phosphonacetyl)-L-aspartic acid.
Topics: Animals; Aspartic Acid; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxycytosine Nucleotides; Deoxyribonucleosides; Drug Synergism; Glycine; Isoxazoles; Leukemia L1210; Mice; Organophosphorus Compounds; Orotic Acid; Oxazoles; Phosphonoacetic Acid; Pyrimidines; Ribonucleosides | 1981 |
Cytostatic activity in vitro of cycloleucine, aspartic acid and glutamic acid phosphonic analogues.
Topics: Amino Acids; Animals; Antineoplastic Agents; Aspartic Acid; Cells, Cultured; Chemical Phenomena; Chemistry; Cycloleucine; Drug Evaluation, Preclinical; Glutamates; Humans; In Vitro Techniques; Leukemia L1210; Mice; Nasopharyngeal Neoplasms; Nasopharynx | 1980 |
Biochemical and antitumor effects of the combination of thymidine and 1-beta-D-arabinofuranosylcytosine against leukemia L1210.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Aspartic Acid; Cells, Cultured; Cytarabine; Cytidine; Drug Therapy, Combination; Leukemia L1210; Mice; Phosphonoacetic Acid; Thymidine | 1981 |
Antitumor activity of the weekly intravenous push schedule of 5-fluoro-2'-deoxyuridine +/- N-phosphonacetyl-L-aspartate in mice bearing advanced colon carcinoma 26.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Colonic Neoplasms; Cytidine Triphosphate; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Floxuridine; Infusions, Intravenous; Leukemia L1210; Mice; Mice, Inbred BALB C; Phosphonoacetic Acid; Uridine Triphosphate | 1993 |
Cellular responses in mouse leukemia L1210 cells made resistant to deoxyadenosine.
Topics: Animals; Apoptosis; Aspartic Acid; Deoxyadenine Nucleotides; Deoxyadenosines; Drug Resistance; Guanosine Triphosphate; Isoxazoles; Leukemia L1210; Mice; Nucleotides; Phosphonoacetic Acid; Ribonucleotide Reductases; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1998 |
Occurrence of the malate-aspartate shuttle in various tumor types.
Topics: Aminooxyacetic Acid; Animals; Antimycin A; Aspartic Acid; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Krebs 2; Cell Line; Cyanides; Kinetics; Lactates; Leukemia L1210; Liver Neoplasms; Malates; Malonates; Mitochondria; NAD; Neoplasms, Experimental; Oxidation-Reduction; Pyruvates; Rotenone; Tricarboxylic Acids | 1976 |
Selective inhibition of pyrimidine synthesis and depletion of nucleotide pools by N-(phosphonacetyl)-L-aspartate.
Topics: Animals; Aspartic Acid; Cells, Cultured; Female; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Organophosphorus Compounds; Orotic Acid; Phosphonoacetic Acid; Pyrazoles; Pyrimidine Nucleotides; Pyrimidines; Ribonucleosides; Uridine | 1979 |
Antitumor activity of N-(phosphonacetyl)-L-aspartic acid, a transition-state inhibitor of aspartate transcarbamylase.
Topics: Animals; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamyl Phosphate; Drug Administration Schedule; Female; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Male; Melanoma; Mice; Neoplasms, Experimental; Organophosphorus Compounds; Osteosarcoma; Phosphonoacetic Acid | 1976 |
Further evidence for a basis of selective activity and relative responsiveness during antifolate therapy of murine tumors.
Topics: Aminopterin; Animals; Aspartic Acid; Carcinoma, Ehrlich Tumor; Chick Embryo; DNA, Neoplasm; Folic Acid Antagonists; Intestine, Small; Leukemia L1210; Liver; Lymphoma; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Quinazolines; Sarcoma 180; Tetrahydrofolate Dehydrogenase; Time Factors | 1975 |
Inhibition of malate-aspartate shuttle by the antitumor drug L-glutamic acid gamma-monohydroxamate in L1210 leukemia cells.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Glutamates; Hydroxamic Acids; Hydroxylamine; Hydroxylamines; Leukemia L1210; Malates; NAD | 1992 |
Failure of L-histidinol to improve the therapeutic efficiency of 5-fluorouracil against murine breast tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cell Cycle; Female; Fluorouracil; Histidinol; Imidazoles; Lethal Dose 50; Leukemia L1210; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Phosphonoacetic Acid | 1987 |
Comparative studies on the transport of aminopterin, methotrexate, and methasquin by the L1210 leukemia cell.
Topics: Aminopterin; Animals; Antineoplastic Agents; Ascitic Fluid; Aspartic Acid; Benzoates; Binding, Competitive; Biological Transport, Active; Cell Line; Cells, Cultured; Diffusion; Folic Acid Antagonists; Leukemia L1210; Methotrexate; Mice; Quinazolines; Streptococcus pneumoniae; Temperature; Tetrahydrofolate Dehydrogenase; Time Factors; Tritium | 1972 |
Synthesis and biological activity of certain 8-mercaptopurine and 6-mercaptopyrimidine S-nucleosides.
Topics: Animals; Aspartic Acid; Bacteriological Techniques; Carcinoma, Ehrlich Tumor; Escherichia coli; Leukemia L1210; Mercaptopurine; Nucleosides; Purines; Pyrimidines; Thiouracil | 1969 |
Synthesis of methyl DL-3-phthalimido-5-oxo-6-diazohexanoate.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Chemistry, Pharmaceutical; Diazooxonorleucine; Imides; Leukemia L1210; Mice; Phthalic Acids; Sarcoma 180 | 1965 |