Page last updated: 2024-11-08

aspartic acid and Kidney Neoplasms

aspartic acid has been researched along with Kidney Neoplasms in 10 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Kidney Neoplasms: Tumors or cancers of the KIDNEY.

Research Excerpts

ExcerptRelevanceReference
"Cellular aspartate drives cancer cell proliferation, but signaling pathways that rewire aspartate biosynthesis to control cell growth remain largely unknown."1.51HIF1α Suppresses Tumor Cell Proliferation through Inhibition of Aspartate Biosynthesis. ( Acker, T; Aragonés, J; Böğürcü-Seidel, N; Bouthelier, A; De Bock, K; Elorza, A; Escasany, E; Fendt, SM; Fraga, E; Fuertes, E; Giménez-Bachs, JM; Hernansanz-Agustín, P; Li, QOY; Lorendeau, D; Martínez-Ruiz, A; Meléndez-Rodríguez, F; Mesa-Ciller, C; Ortega Muelas, M; Pérez, B; Rinaldi, G; Roche, O; Salinas-Sánchez, AS; Sánchez Prieto, R; Tello, D; Torres-Capelli, M; Turiel, G; Urrutia, AA, 2019)
"WAGR syndrome is an acronym for a rare constellation of congenital abnormalities including predisposition to Wilms' tumor, Aniridia, Genitourinary malformations, and mental Retardation."1.29Altered trans-activational properties of a mutated WT1 gene product in a WAGR-associated Wilms' tumor. ( Haber, DA; Nisen, P; Park, S; Tomlinson, G, 1993)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's2 (20.00)18.2507
2000's2 (20.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Meléndez-Rodríguez, F1
Urrutia, AA1
Lorendeau, D1
Rinaldi, G1
Roche, O1
Böğürcü-Seidel, N1
Ortega Muelas, M1
Mesa-Ciller, C1
Turiel, G1
Bouthelier, A1
Hernansanz-Agustín, P1
Elorza, A1
Escasany, E1
Li, QOY1
Torres-Capelli, M1
Tello, D1
Fuertes, E1
Fraga, E1
Martínez-Ruiz, A1
Pérez, B1
Giménez-Bachs, JM1
Salinas-Sánchez, AS1
Acker, T1
Sánchez Prieto, R1
Fendt, SM1
De Bock, K1
Aragonés, J1
Cardaci, S1
Zheng, L1
MacKay, G1
van den Broek, NJ1
MacKenzie, ED1
Nixon, C1
Stevenson, D1
Tumanov, S1
Bulusu, V1
Kamphorst, JJ1
Vazquez, A1
Fleming, S1
Schiavi, F1
Kalna, G1
Blyth, K1
Strathdee, D1
Gottlieb, E1
Eikesdal, HP1
Sugimoto, H1
Birrane, G1
Maeshima, Y1
Cooke, VG1
Kieran, M1
Kalluri, R1
Lanthier, J1
Desrosiers, RR1
Earhart, RH1
Elson, PJ1
Rosenthal, SN1
Hahn, RG1
Slayton, RE1
Natale, RB1
Yagoda, A1
Kelsen, DP1
Gralla, RJ1
Watson, RC1
Park, S1
Tomlinson, G1
Nisen, P1
Haber, DA1
Cleaveland, ES1
Zaharevitz, DW1
Kelley, JA1
Paull, K1
Cooney, DA1
Ford, H1
Jackson, RC2
Morris, HP2
Weber, G2

Other Studies

10 other studies available for aspartic acid and Kidney Neoplasms

ArticleYear
HIF1α Suppresses Tumor Cell Proliferation through Inhibition of Aspartate Biosynthesis.
    Cell reports, 2019, 02-26, Volume: 26, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Aspartate Aminotransferase, Cytoplasmic; Aspartate Aminotransferase,

2019
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.
    Nature cell biology, 2015, Volume: 17, Issue:10

    Topics: Animals; Aspartic Acid; Carboxylic Acids; Carcinoma, Renal Cell; Cell Line, Transformed; Cell Prolif

2015
Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Sep-30, Volume: 105, Issue:39

    Topics: Amino Acid Substitution; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoc

2008
Protein L-isoaspartyl methyltransferase repairs abnormal aspartyl residues accumulated in vivo in type-I collagen and restores cell migration.
    Experimental cell research, 2004, Feb-01, Volume: 293, Issue:1

    Topics: Aging; Animals; Aspartic Acid; Cell Adhesion; Cell Line, Tumor; Cell Movement; Collagen Type I; Dros

2004
Phase II study of PALA and AMSA in advanced renal cell carcinoma.
    American journal of clinical oncology, 1983, Volume: 6, Issue:5

    Topics: Adenocarcinoma; Aminoacridines; Amsacrine; Antimetabolites, Antineoplastic; Antineoplastic Agents; A

1983
Phase II trial of PALA in hypernephroma and urinary bladder cancer.
    Cancer treatment reports, 1982, Volume: 66, Issue:12

    Topics: Adenocarcinoma; Aspartic Acid; Drug Evaluation; Humans; Kidney Neoplasms; Neoplasm Metastasis; Organ

1982
Altered trans-activational properties of a mutated WT1 gene product in a WAGR-associated Wilms' tumor.
    Cancer research, 1993, Oct-15, Volume: 53, Issue:20

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Chloramphenicol O-

1993
Identification of a novel inhibitor (NSC 665564) of dihydroorotate dehydrogenase with a potency equivalent to brequinar.
    Biochemical and biophysical research communications, 1996, Jun-25, Volume: 223, Issue:3

    Topics: Antineoplastic Agents; Aspartic Acid; Biphenyl Compounds; Breast Neoplasms; Carbolines; Carcinoma, N

1996
Neoplastic transformation-linked alterations in adenylosuccinate synthetase activity.
    Biochemical and biophysical research communications, 1975, Sep-16, Volume: 66, Issue:2

    Topics: Aging; Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Inosine N

1975
Enzymes of the purine ribonucleotide cycle in rat hepatomas and kidney tumors.
    Cancer research, 1977, Volume: 37, Issue:9

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; AMP Deaminase; Animals; Animals, Newborn; Antimetab

1977