Page last updated: 2024-11-08

aspartic acid and Ischemic Attack, Transient

aspartic acid has been researched along with Ischemic Attack, Transient in 68 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)

Research Excerpts

ExcerptRelevanceReference
"The authors compared temporal profiles of N-acetylaspartate (NAA) and the NAA/total creatine ratio with neuronal and astrocytic densities and with tissue atrophy in the hippocampal CA1 sector of gerbils after 5-minute bilateral forebrain ischemia and subsequent reperfusion for up to 6 months."7.72N-acetylaspartate to total creatine ratio in the hippocampal CA1 sector after transient cerebral ischemia in gerbils: influence of neuronal elements, reactive gliosis, and tissue atrophy. ( Konaka, K; Li, JY; Matsumoto, M; Sakoda, S; Ueda, H; Yanagihara, T, 2003)
"The authors compared temporal profiles of N-acetylaspartate (NAA) and the NAA/total creatine ratio with neuronal and astrocytic densities and with tissue atrophy in the hippocampal CA1 sector of gerbils after 5-minute bilateral forebrain ischemia and subsequent reperfusion for up to 6 months."3.72N-acetylaspartate to total creatine ratio in the hippocampal CA1 sector after transient cerebral ischemia in gerbils: influence of neuronal elements, reactive gliosis, and tissue atrophy. ( Konaka, K; Li, JY; Matsumoto, M; Sakoda, S; Ueda, H; Yanagihara, T, 2003)
"We investigated whether patients with transient ischemic attack (TIA) have systemic low flow to the brain or an abnormal intracranial flow distribution caused by an abnormal anatomy of the circle of Willis."2.70Hemodynamic and metabolic changes in transient ischemic attack patients: a magnetic resonance angiography and (1)H-magnetic resonance spectroscopy study performed within 3 days of onset of a transient ischemic attack. ( Bisschops, RH; Kappelle, LJ; Mali, WP; van der Grond, J, 2002)
"We modeled transient ischemic attacks and strokes in mice."1.37Early predictive biomarkers for lesion after transient cerebral ischemia. ( Berthet, C; Gruetter, R; Hirt, L; Lei, H, 2011)
"We investigated whether patients with transient ischemic attack (TIA) have metabolic changes in the brain."1.361H-MR spectroscopy changes in transient ischemic attack patients and their correlation with perfusion-weighted imaging. ( Tong, T; Xiaoyuan, F; Zhenwei, Y, 2010)
"The metyrapone treatment morphologically improved the damage provoked by 3 min of ischemia, although it did not alleviate the damage by 5 min."1.30Metyrapone alleviates ischemic neuronal damage in the gerbil hippocampus. ( Adachi, N; Arai, T; Chen, J; Liu, K; Nagaro, T, 1999)
"GYKI 52466 failed to inhibit this increase."1.29Effect of the non-NMDA receptor antagonist GYKI 52466 on the microdialysate and tissue concentrations of amino acids following transient forebrain ischaemia. ( Arvin, B; Chapman, AG; Graham, JL; Lekieffre, D; Meldrum, BS; Moncada, C, 1994)
"Cerebral ischemia associated with subarachnoid hemorrhage may have severe consequences for neuronal functioning."1.29Intracerebral microdialysis of glutamate and aspartate in two vascular territories after aneurysmal subarachnoid hemorrhage. ( Boris-Möller, F; Brandt, L; Nilsson, OG; Säveland, H; Wieloch, T, 1996)
"Hypoglycemia or anoxia alone affected the release only marginally."1.27Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitro. ( Benveniste, H; Diemer, NH; Drejer, J; Schousboe, A, 1985)
" Two potent, selective and competitive NMDA antagonists, cis-4-(phosphonomethyl)-2-piperidine-carboxylic acid (CGS 19755) and 4-(3-phosphonopropyl)-2-piperazine-carboxylic acid (CPP), were characterized in the gerbil ischemia model with respect to dose-response and time course effects."1.27The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils. ( Boast, CA; Etienne, PE; Gerhardt, SC; Lehmann, J; Liebman, JM; Pastor, G, 1988)

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-199014 (20.59)18.7374
1990's36 (52.94)18.2507
2000's13 (19.12)29.6817
2010's5 (7.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jiang, Z1
Li, C1
Manuel, ML1
Yuan, S1
Kevil, CG1
McCarter, KD1
Lu, W1
Sun, H1
Lei, H4
Berthet, C3
Hirt, L3
Gruetter, R3
Tong, T1
Zhenwei, Y1
Xiaoyuan, F1
Alf, MF1
Mlynarik, V1
Qian, J1
Qian, B1
Bakker, FC1
Klijn, CJ2
Jennekens-Schinkel, A1
van der Tweel, I1
van der Grond, J3
van Huffelen, AC1
Tulleken, CA3
Kappelle, LJ3
Wei, J1
Cohen, DM1
Quast, MJ1
Konaka, K2
Ueda, H3
Li, JY3
Matsumoto, M4
Sakoda, S2
Yanagihara, T3
Nakano, M2
Vial, F1
Serriere, S1
Barantin, L1
Montharu, J1
Nadal-Desbarats, L1
Pourcelot, L1
Seguin, F1
Ritz, MF1
Schmidt, P1
Mendelowitsch, A1
Benveniste, H2
Drejer, J2
Schousboe, A3
Diemer, NH3
Buisson, A1
Margaill, I1
Callebert, J3
Plotkine, M3
Boulu, RG3
Sager, TN2
Laursen, H1
Hansen, AJ1
Phillis, JW4
Perkins, LM2
Smith-Barbour, M1
O'Regan, MH4
Lekieffre, D2
Meldrum, BS5
Anderson, KJ1
Nellgård, B1
Wieloch, T4
Torp, R1
Arvin, B2
Le Peillet, E1
Chapman, AG2
Ottersen, OP1
Graham, JL1
Moncada, C1
Graham, SH2
Shimizu, H1
Newman, A1
Weinstein, P1
Faden, AI1
Ghribi, O2
Green, AR1
Cross, AJ1
Xu, CQ1
Li, LX1
Wang, ZC1
Matsumoto, K1
Lo, EH1
Pierce, AR1
Halpern, EF1
Newcomb, R1
Wu, G1
Kim, HK1
Zornow, MH3
van der Toorn, A1
Dijkhuizen, RM1
Nicolay, K1
Nagatomo, Y1
Wick, M1
Prielmeier, F1
Frahm, J1
Säveland, H1
Nilsson, OG1
Boris-Möller, F2
Brandt, L1
Handa, Y1
Kaneko, M1
Matuda, T1
Kobayashi, H1
Kubota, T1
Puka-Sundvall, M1
Sandberg, M1
Hagberg, H1
Penrice, J1
Lorek, A1
Cady, EB1
Amess, PN1
Wylezinska, M1
Cooper, CE1
D'Souza, P1
Brown, GC1
Kirkbride, V1
Edwards, AD1
Wyatt, JS1
Reynolds, EO1
Araki, T1
Kato, H1
Kogure, K1
Itoyama, Y1
Song, D1
Adachi, N1
Chen, J2
Liu, K1
Nagaro, T1
Arai, T1
Heim, C1
Zhang, J1
Lan, J1
Sieklucka, M1
Kurz, T1
Riederer, P1
Gerlach, M1
Sontag, KH1
Rutgers, DR1
Guyot, LL1
Diaz, FG1
Ren, J1
Topp, S1
Torup, L1
Hanson, LG1
Egestad, B1
Møller, A1
Bisschops, RH1
Mali, WP1
Favalli, L1
Rozza, A1
Frattini, P1
Masoero, E1
Scelsi, R1
Pascale, A1
Govoni, S1
Timoshchuk, VL1
Kawakami, S1
Kobayashi, K1
Hossmann, KA1
Kleihues, P1
Simpson, RE1
Scheller, MS2
Strnat, MA1
Berkelbach van der Sprenkel, JW1
Knufman, NM1
van Rijen, PC1
Luyten, PR1
den Hollander, JA1
Katsura, M1
Iino, T1
Kuriyama, K1
Swan, JH2
Leach, MJ1
Millan, MH1
Gwinn, R1
Kadota, K1
Simon, RP1
Lombardi, G1
Moroni, F1
Felber, S1
Luef, G1
Aichner, F1
Ooboshi, H1
Yao, H1
Matsumoto, T1
Hirano, M1
Uchimura, H1
Sadoshima, S1
Fujishima, M1
Baker, AJ1
Grafe, MR1
Skilling, SR1
Smullin, DH1
Larson, AA1
Huang, QF1
Gebrewold, A1
Altura, BT1
Altura, BM1
Buchan, A1
Pulsinelli, WA1
Roman, R1
Bartkowski, H1
Simon, R1
Kolluri, VR1
Lakshmi, GY1
Steinberg, GK2
Saleh, J2
Kunis, D2
DeLaPaz, R2
Zarnegar, SR2
Nielsen, EO1
Aarslew-Jensen, M1
Krogsgaard-Larsen, P1
Evans, MC1
Westerberg, E1
Monaghan, DT1
Cotman, CW1
Boast, CA1
Gerhardt, SC1
Pastor, G1
Lehmann, J1
Etienne, PE1
Liebman, JM1
Ljunggren, B2
Schutz, H1
Siesjö, BK2
Ratcheson, RA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Brain Changes in Pediatric Obstructive Sleep Apnea[NCT05368077]70 participants (Anticipated)Interventional2022-05-14Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aspartic acid and Ischemic Attack, Transient

ArticleYear
[Effect of excitatory amino acids, Ca2+ on delayed neuronal death in hippocampus following transient forebrain ischemia].
    Sheng li ke xue jin zhan [Progress in physiology], 1993, Volume: 24, Issue:2

    Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Calcium-Transporting ATPases; Glutamates; Glutamic Aci

1993

Trials

2 trials available for aspartic acid and Ischemic Attack, Transient

ArticleYear
Cognitive impairment is related to cerebral lactate in patients with carotid artery occlusion and ipsilateral transient ischemic attacks.
    Stroke, 2003, Volume: 34, Issue:6

    Topics: Adult; Aged; Aspartic Acid; Blood Flow Velocity; Brain; Carbon Dioxide; Carotid Artery Diseases; Cer

2003
Hemodynamic and metabolic changes in transient ischemic attack patients: a magnetic resonance angiography and (1)H-magnetic resonance spectroscopy study performed within 3 days of onset of a transient ischemic attack.
    Stroke, 2002, Volume: 33, Issue:1

    Topics: Adult; Aged; Aspartic Acid; Brain; Cerebral Arteries; Cerebrovascular Circulation; Choline; Circle o

2002

Other Studies

65 other studies available for aspartic acid and Ischemic Attack, Transient

ArticleYear
Role of hydrogen sulfide in early blood-brain barrier disruption following transient focal cerebral ischemia.
    PloS one, 2015, Volume: 10, Issue:2

    Topics: Alkynes; Animals; Aspartic Acid; Blood-Brain Barrier; Cerebral Cortex; Cystathionine beta-Synthase;

2015
Evolution of the neurochemical profile after transient focal cerebral ischemia in the mouse brain.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2009, Volume: 29, Issue:4

    Topics: Animals; Aspartic Acid; Cerebrovascular Circulation; Corpus Striatum; Glucose; Glutamic Acid; Glutam

2009
1H-MR spectroscopy changes in transient ischemic attack patients and their correlation with perfusion-weighted imaging.
    The International journal of neuroscience, 2010, Volume: 120, Issue:9

    Topics: Aged; Aspartic Acid; Brain; Cerebrovascular Circulation; Choline; Creatine; Female; Humans; Hydrogen

2010
Early predictive biomarkers for lesion after transient cerebral ischemia.
    Stroke, 2011, Volume: 42, Issue:3

    Topics: Animals; Aspartic Acid; Biomarkers; Disease Models, Animal; Glutamine; Ischemic Attack, Transient; M

2011
High-resolution spatial mapping of changes in the neurochemical profile after focal ischemia in mice.
    NMR in biomedicine, 2012, Volume: 25, Issue:2

    Topics: Animals; Aspartic Acid; Brain Ischemia; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Infarct

2012
Reversible loss of N-acetylaspartate after 15-min transient middle cerebral artery occlusion in rat: a longitudinal study with in vivo proton magnetic resonance spectroscopy.
    Neurochemical research, 2013, Volume: 38, Issue:1

    Topics: Animals; Aspartic Acid; Creatine; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Lo

2013
Effects of 2-deoxy-d-glucose on focal cerebral ischemia in hyperglycemic rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:5

    Topics: Animals; Antimetabolites; Aspartic Acid; Deoxyglucose; Hyperglycemia; Infarction, Middle Cerebral Ar

2003
N-acetylaspartate to total creatine ratio in the hippocampal CA1 sector after transient cerebral ischemia in gerbils: influence of neuronal elements, reactive gliosis, and tissue atrophy.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:6

    Topics: Animals; Aspartic Acid; Astrocytes; Atrophy; Cell Count; Common Variable Immunodeficiency; Creatine;

2003
Regional N-acetyl-aspartate level and immunohistochemical damage in the hippocampus after transient forebrain ischemia in gerbils.
    Acta neurochirurgica. Supplement, 2003, Volume: 86

    Topics: Animals; Aspartic Acid; Gerbillinae; Hippocampus; Immunohistochemistry; Ischemic Attack, Transient;

2003
A newborn piglet study of moderate hypoxic-ischemic brain injury by 1H-MRS and MRI.
    Magnetic resonance imaging, 2004, Volume: 22, Issue:4

    Topics: Animals; Animals, Newborn; Aspartic Acid; Basal Ganglia; Cerebral Cortex; Cerebrovascular Circulatio

2004
Acute effects of 17beta-estradiol on the extracellular concentration of excitatory amino acids and energy metabolites during transient cerebral ischemia in male rats.
    Brain research, 2004, Oct-01, Volume: 1022, Issue:1-2

    Topics: Analysis of Variance; Animals; Aspartic Acid; Brain Infarction; Chromatography, High Pressure Liquid

2004
Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis.
    Journal of neurochemistry, 1984, Volume: 43, Issue:5

    Topics: Amino Acids; Animals; Aspartic Acid; Blood-Brain Barrier; Dialysis; Extracellular Space; Glutamates;

1984
Mechanisms involved in the neuroprotective activity of a nitric oxide synthase inhibitor during focal cerebral ischemia.
    Journal of neurochemistry, 1993, Volume: 61, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Aspartic Acid; Blood Pressure; Corpus Striatum; Gluta

1993
Changes in N-acetyl-aspartate content during focal and global brain ischemia of the rat.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1995, Volume: 15, Issue:4

    Topics: Animals; Aspartic Acid; Brain; Drug Stability; Glutamic Acid; Ischemic Attack, Transient; Kinetics;

1995
Transmitter amino acid release from rat neocortex: complete versus incomplete ischemia models.
    Neurochemical research, 1994, Volume: 19, Issue:11

    Topics: Animals; Aspartic Acid; Blood Pressure; Cerebral Cortex; Chromatography, High Pressure Liquid; Extra

1994
The pyrimidine-derivative, BW1003C87, protects CA1 and striatal neurons following transient severe forebrain ischaemia in rats. A microdialysis and histological study.
    Neuroscience, 1993, Volume: 56, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Dose-Response Relationship, Drug; gamma-Aminob

1993
Ischemia-induced upregulation of excitatory amino acid transport sites.
    Brain research, 1993, Sep-17, Volume: 622, Issue:1-2

    Topics: Animals; Aspartic Acid; Binding Sites; Biological Transport; Glutamates; Glutamic Acid; Ischemic Att

1993
Effect of ischaemia and reperfusion on the extra- and intracellular distribution of glutamate, glutamine, aspartate and GABA in the rat hippocampus, with a note on the effect of the sodium channel blocker BW1003C87.
    Experimental brain research, 1993, Volume: 96, Issue:3

    Topics: Animals; Aspartic Acid; Calcium Channel Blockers; Extracellular Space; gamma-Aminobutyric Acid; Glut

1993
Effect of the non-NMDA receptor antagonist GYKI 52466 on the microdialysate and tissue concentrations of amino acids following transient forebrain ischaemia.
    Journal of neurochemistry, 1994, Volume: 62, Issue:4

    Topics: Amino Acids; Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Cerebral Cortex; Corpus S

1994
Opioid receptor antagonist nalmefene stereospecifically inhibits glutamate release during global cerebral ischemia.
    Brain research, 1993, Dec-31, Volume: 632, Issue:1-2

    Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; gamma-A

1993
Effect of kynurenic acid on the ischaemia-induced accumulation of glutamate in rat striatum.
    Neuroreport, 1994, Jan-12, Volume: 5, Issue:4

    Topics: Animals; Aspartic Acid; Corpus Striatum; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Aci

1994
Competitive NMDA receptor blockers reduce striatal glutamate accumulation in ischaemia.
    Neuroreport, 1994, Jun-02, Volume: 5, Issue:10

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Extracellular Spa

1994
Attenuation by chlormethiazole of oedema following focal ischaemia in the cerebral cortex of the rat.
    Neuroscience letters, 1994, May-23, Volume: 173, Issue:1-2

    Topics: Animals; Aspartic Acid; Body Water; Brain Edema; Cerebral Cortex; Cerebral Infarction; Cerebrovascul

1994
Secondary elevation of extracellular neurotransmitter amino acids in the reperfusion phase following focal cerebral ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1996, Volume: 16, Issue:1

    Topics: Amino Acids; Analysis of Variance; Animals; Aspartic Acid; Basal Ganglia; Cerebral Cortex; Cerebrosp

1996
Transient brain ischemia in rabbits: the effect of omega-conopeptide MVIIC on hippocampal excitatory amino acids.
    Brain research, 1995, Sep-18, Volume: 692, Issue:1-2

    Topics: Animals; Aspartic Acid; Blood Pressure; Calcium Channel Blockers; Electroencephalography; Excitatory

1995
T1 and T2 relaxation times of the major 1H-containing metabolites in rat brain after focal ischemia.
    NMR in biomedicine, 1995, Volume: 8, Issue:6

    Topics: Animals; Aspartic Acid; Brain; Choline; Creatine; Glutamic Acid; Glutamine; Ischemic Attack, Transie

1995
Dynamic monitoring of cerebral metabolites during and after transient global ischemia in rats by quantitative proton NMR spectroscopy in vivo.
    NMR in biomedicine, 1995, Volume: 8, Issue:6

    Topics: Animals; Aspartic Acid; Brain; Choline; Creatine; Glucose; Glycogen; Inositol; Ischemic Attack, Tran

1995
Intracerebral microdialysis of glutamate and aspartate in two vascular territories after aneurysmal subarachnoid hemorrhage.
    Neurosurgery, 1996, Volume: 38, Issue:1

    Topics: Adult; Aged; Aneurysm, Ruptured; Aspartic Acid; Brain Ischemia; Female; Frontal Lobe; Glutamic Acid;

1996
In vivo proton magnetic resonance spectroscopy for metabolic changes in brain during chronic cerebral vasospasm in primates.
    Neurosurgery, 1997, Volume: 40, Issue:4

    Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Cerebral Angiography; Cerebrovascular Circulation; Ch

1997
Brain injury after hypoxia-ischemia in newborn rats: relationship to extracellular levels of excitatory amino acids and cysteine.
    Brain research, 1997, Mar-07, Volume: 750, Issue:1-2

    Topics: Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Injuries; Carotid Arter

1997
Proton magnetic resonance spectroscopy of the brain during acute hypoxia-ischemia and delayed cerebral energy failure in the newborn piglet.
    Pediatric research, 1997, Volume: 41, Issue:6

    Topics: Animals; Animals, Newborn; Aspartic Acid; Asphyxia Neonatorum; Brain; Creatine; Energy Metabolism; H

1997
Post-ischaemic alteration of excitatory amino acid transport sites in the gerbil hippocampus.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:12

    Topics: Animals; Aspartic Acid; Astrocytes; Autoradiography; Binding Sites; Dentate Gyrus; Gerbillinae; Glia

1997
Tamoxifen, a chloride channel blocker, reduces glutamate and aspartate release from the ischemic cerebral cortex.
    Brain research, 1998, Jan-12, Volume: 780, Issue:2

    Topics: Animals; Aspartic Acid; Cerebral Cortex; Chloride Channels; Estrogen Antagonists; Glutamic Acid; Isc

1998
Changes in the extracellular levels of glutamate and aspartate during ischemia and hypoglycemia. Effects of hypothermia.
    Experimental brain research, 1998, Volume: 121, Issue:3

    Topics: Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Extracellular Space; Glutamic Acid; Hypogl

1998
Measurement of regional N-acetylaspartate after transient global ischemia in gerbils with and without ischemic tolerance: an index of neuronal survival.
    Annals of neurology, 1998, Volume: 44, Issue:3

    Topics: Animals; Aspartic Acid; Cell Survival; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Ischemi

1998
Metyrapone alleviates ischemic neuronal damage in the gerbil hippocampus.
    European journal of pharmacology, 1999, Jun-04, Volume: 373, Issue:2-3

    Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Cytophotometry; Gerbillinae; Glutamates; Glycine; Hipp

1999
Cerebral oligaemia episode triggers free radical formation and late cognitive deficiencies.
    The European journal of neuroscience, 2000, Volume: 12, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Carotid Stenosis; Cognition Disorders; Corpu

2000
Cerebral metabolic changes in patients with a symptomatic occlusion of the internal carotid artery: a longitudinal 1H magnetic resonance spectroscopy study.
    Journal of magnetic resonance imaging : JMRI, 2000, Volume: 11, Issue:3

    Topics: Aged; Amaurosis Fugax; Aspartic Acid; Brain; Carotid Artery, Internal; Carotid Stenosis; Choline; Cr

2000
The effect of intravenous insulin on accumulation of excitotoxic and other amino acids in the ischemic rat cerebral cortex.
    Neuroscience letters, 2000, Jul-07, Volume: 288, Issue:1

    Topics: Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Energy Metabolism; gamma-Aminobutyric Acid

2000
Evaluation of CA1 damage using single-voxel 1H-MRS and un-biased stereology: Can non-invasive measures of N-acetyl-asparate following global ischemia be used as a reliable measure of neuronal damage?
    Brain research, 2001, Feb-16, Volume: 892, Issue:1

    Topics: Animals; Aspartic Acid; Biomarkers; Brain; Chromatography, High Pressure Liquid; Gerbillinae; Hippoc

2001
Ischemia-induced glutamate release in rat frontoparietal cortex after chronic alcohol and withdrawal.
    Neuroscience letters, 2002, Jul-05, Volume: 326, Issue:3

    Topics: Alcoholism; Animals; Aspartic Acid; Central Nervous System Depressants; Dialysis Solutions; Ethanol;

2002
[Effect of rheopolyglucin with panangin on the cytochemical indicators of leukocytes in patients with ischemic cerebral infarct].
    Klinicheskaia meditsina, 1976, Volume: 54, Issue:9

    Topics: Acid Phosphatase; Aged; Alkaline Phosphatase; Aspartic Acid; Dextrans; Electron Transport Complex IV

1976
[Recovery after complete cerebral ischemia: free amino acid levels in the brain tissue during and after complete cerebral ischemia (author's transl)].
    No to shinkei = Brain and nerve, 1978, Volume: 30, Issue:2

    Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Brain Chemistry; Cats; gamma-Aminobutyric

1978
The selective A2 adenosine receptor agonist CGS 21680 enhances excitatory transmitter amino acid release from the ischemic rat cerebral cortex.
    Neuroscience letters, 1992, Apr-13, Volume: 138, Issue:1

    Topics: Adenosine; Analysis of Variance; Animals; Antihypertensive Agents; Aspartic Acid; Cerebral Cortex; G

1992
AMPA and NMDA receptor antagonists do not decrease hippocampal glutamate concentrations during transient global ischemia.
    Anesthesiology, 1992, Volume: 77, Issue:4

    Topics: Animals; Aspartic Acid; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ischem

1992
Proton spectroscopic imaging in cerebral ischaemia. Where we stand and what can be expected.
    Advances and technical standards in neurosurgery, 1992, Volume: 19

    Topics: Aspartic Acid; Brain; Brain Ischemia; Brain Mapping; Choline; Energy Metabolism; Humans; Image Inter

1992
Changes in content of neuroactive amino acids and acetylcholine in the rat hippocampus following transient forebrain ischemia.
    Neurochemistry international, 1992, Volume: 21, Issue:2

    Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Ac

1992
Reduction of glutamate release and protection against ischemic brain damage by BW 1003C87.
    Brain research, 1992, Oct-09, Volume: 593, Issue:1

    Topics: Animals; Aspartic Acid; Brain; Caudate Nucleus; Cerebral Arteries; Glutamates; Glutamine; In Vitro T

1992
GM1 ganglioside reduces ischemia-induced excitatory amino acid output: a microdialysis study in the gerbil hippocampus.
    Neuroscience letters, 1992, Jan-06, Volume: 134, Issue:2

    Topics: Animals; Aspartic Acid; Dialysis; Female; G(M1) Ganglioside; Gerbillinae; Glutamates; Hippocampus; I

1992
1-H-localized magnetic resonance spectroscopy: preliminary observations in transient ischemic attacks.
    Journal of the neurological sciences, 1992, Volume: 108, Issue:1

    Topics: Aged; Aspartic Acid; Brain; Brain Chemistry; Female; Humans; Ischemic Attack, Transient; Lactates; L

1992
Excitatory and inhibitory amino acid changes in ischemic brain regions in spontaneously hypertensive rats.
    Neurochemical research, 1991, Volume: 16, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Brain; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Aci

1991
Hypothermia prevents ischemia-induced increases in hippocampal glycine concentrations in rabbits.
    Stroke, 1991, Volume: 22, Issue:5

    Topics: Animals; Aspartic Acid; Brain; Glutamates; Glycine; Hippocampus; Hypothermia, Induced; Ischemic Atta

1991
Magnesium ions prevent phencyclidine-induced cerebrovasospasms and rupture of cerebral microvessels: direct in-vivo microcirculatory studies on the rat brain.
    Neuroscience letters, 1990, May-18, Volume: 113, Issue:1

    Topics: Animals; Aspartic Acid; Cerebrovascular Circulation; Cerebrovascular Disorders; Female; Ischemic Att

1990
Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:1

    Topics: Animals; Aspartic Acid; Body Temperature; Dibenzocycloheptenes; Dizocilpine Maleate; Female; Gerbill

1990
The specific NMDA receptor antagonist AP-7 attenuates focal ischemic brain injury.
    Neuroscience letters, 1989, Sep-25, Volume: 104, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Ischemic Attack, Transient; Kineti

1989
Changes in regional levels of putative neurotransmitter amino acids in brain under unilateral forebrain ischemia.
    Neurochemical research, 1989, Volume: 14, Issue:7

    Topics: Animals; Aspartic Acid; Brain; Cerebral Cortex; Corpus Striatum; Female; gamma-Aminobutyric Acid; Ge

1989
Protective effect of N-methyl-D-aspartate antagonists after focal cerebral ischemia in rabbits.
    Stroke, 1989, Volume: 20, Issue:9

    Topics: Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Dextromethorphan; Dextrorphan; Ischemic At

1989
Pretreatment with the NMDA antagonist dextrorphan reduces cerebral injury following transient focal ischemia in rabbits.
    Brain research, 1989, Sep-18, Volume: 497, Issue:2

    Topics: Animals; Aspartic Acid; Brain; Brain Edema; Cerebral Cortex; Dextrorphan; Ischemic Attack, Transient

1989
Baclofen-induced, calcium-dependent stimulation of in vivo release of D-[3H]aspartate from rat hippocampus monitored by intracerebral microdialysis.
    Neurochemical research, 1989, Volume: 14, Issue:4

    Topics: Animals; Aspartic Acid; Baclofen; Calcium; GABA Antagonists; Hippocampus; Ischemic Attack, Transient

1989
Long-term development of selective neuronal loss and the mechanism of protection by 2-amino-7-phosphonoheptanoate in a rat model of incomplete forebrain ischaemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1988, Volume: 8, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cell Survival; Ce

1988
Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitro.
    Journal of neurochemistry, 1985, Volume: 45, Issue:1

    Topics: Animals; Aspartic Acid; Astrocytes; Brain; Calcium; Cells, Cultured; Cerebellum; Dialysis; Glutamate

1985
Excitatory amino acid receptors and ischemic brain damage in the rat.
    Neuroscience letters, 1987, Jan-14, Volume: 73, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; H

1987
The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils.
    Brain research, 1988, Mar-01, Volume: 442, Issue:2

    Topics: Animals; Aspartic Acid; Brain; Female; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Motor A

1988
Changes in energy state and acid-base parameters of the rat brain during complete compression ischemia.
    Brain research, 1974, Jun-20, Volume: 73, Issue:2

    Topics: Acid-Base Equilibrium; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosp

1974
Cerebral metabolic state following complete compression ischemia.
    Brain research, 1974, Jun-20, Volume: 73, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Ammo

1974