aspartic acid has been researched along with Ischemia in 45 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We compared the neuroprotective effects of the noncompetitive NMDA-receptor antagonist MK-801 and the opiate-receptor antagonist nalmefene in a model of global spinal cord ischemia and reperfusion in unanesthetized rabbits." | 7.68 | Comparison of the neuroprotective effects of the N-methyl-D-aspartate antagonist MK-801 and the opiate-receptor antagonist nalmefene in experimental spinal cord ischemia. ( Faden, AI; Yum, SW, 1990) |
| "It was concluded that in brain metastases of mammary carcinoma Lact represents a product of ischemia preceding/during tissue decay resulting in central necrosis, rather than tumor specific metabolism resulting in increased glycolysis." | 5.29 | Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma. ( Oudkerk, M; Sijens, PE; van Dijk, P, 1994) |
| "In experiments on rats we studied the effects of cardioplegic solutions with L-aspartic acid or L-arginine on functional recovery and metabolism of isolated working heart after 40-min normothermal global ischemia and 30-min reperfusion." | 3.73 | Efficiency of cardioplegic solutions containing L-arginine and L-aspartic acid. ( Pisarenko, OI; Shul'zhenko, VS; Studneva, IM, 2006) |
| " We compared the neuroprotective effects of the noncompetitive NMDA-receptor antagonist MK-801 and the opiate-receptor antagonist nalmefene in a model of global spinal cord ischemia and reperfusion in unanesthetized rabbits." | 3.68 | Comparison of the neuroprotective effects of the N-methyl-D-aspartate antagonist MK-801 and the opiate-receptor antagonist nalmefene in experimental spinal cord ischemia. ( Faden, AI; Yum, SW, 1990) |
| "Ischemia is believed to induce neuronal damage by causing a sustained increase in the level of extracellular excitatory amino acids." | 1.30 | Role of glutamate receptors and voltage-dependent calcium and sodium channels in the extracellular glutamate/aspartate accumulation and subsequent neuronal injury induced by oxygen/glucose deprivation in cultured hippocampal neurons. ( Katayama, K; Kimura, M; Kuwada, M; Miyagawa, T; Nishizawa, Y; Sawada, K, 1998) |
| "It was concluded that in brain metastases of mammary carcinoma Lact represents a product of ischemia preceding/during tissue decay resulting in central necrosis, rather than tumor specific metabolism resulting in increased glycolysis." | 1.29 | Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma. ( Oudkerk, M; Sijens, PE; van Dijk, P, 1994) |
| "Hypoxic-hypoglycemic treatment (in vitro ischemia) elicited a rapid release of the excitatory amino acids from cultured spinal cord neurons and glial cells, but the release was greater from glial cells than from neurons." | 1.29 | Role of aspartate in ischemic spinal cord damage. ( Kataoka, K; Nakamura, Y; Ogata, T; Okumura, H; Shibata, T; Tsuji, K, 1996) |
| "Pretreatment with allopurinol, dibenzyline, methylprednisolone, glucagon, ATP-MgCl2 and aspartic acid reduced the overall mortality of ischemic liver injury." | 1.26 | Ischemic damage of the liver. Part II: In vivo investigation of the prevention of the ischemic lesion of the liver. ( Kokas, P; Kupcsulik, P, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (28.89) | 18.7374 |
| 1990's | 14 (31.11) | 18.2507 |
| 2000's | 15 (33.33) | 29.6817 |
| 2010's | 3 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Russo, R | 1 |
| Cavaliere, F | 1 |
| Varano, GP | 1 |
| Milanese, M | 1 |
| Adornetto, A | 1 |
| Nucci, C | 1 |
| Bonanno, G | 1 |
| Morrone, LA | 1 |
| Corasaniti, MT | 1 |
| Bagetta, G | 1 |
| Mango, D | 1 |
| Barbato, G | 1 |
| Piccirilli, S | 1 |
| Panico, MB | 1 |
| Feligioni, M | 1 |
| Schepisi, C | 1 |
| Graziani, M | 1 |
| Porrini, V | 1 |
| Benarese, M | 1 |
| Lanzillotta, A | 1 |
| Pizzi, M | 1 |
| Pieraccini, S | 1 |
| Sironi, M | 1 |
| Blandini, F | 1 |
| Nicoletti, F | 1 |
| Mercuri, NB | 1 |
| Imbimbo, BP | 1 |
| Nisticò, R | 1 |
| Chouchani, ET | 1 |
| Pell, VR | 1 |
| Gaude, E | 1 |
| Aksentijević, D | 1 |
| Sundier, SY | 1 |
| Robb, EL | 1 |
| Logan, A | 1 |
| Nadtochiy, SM | 1 |
| Ord, ENJ | 1 |
| Smith, AC | 1 |
| Eyassu, F | 1 |
| Shirley, R | 1 |
| Hu, CH | 1 |
| Dare, AJ | 1 |
| James, AM | 1 |
| Rogatti, S | 1 |
| Hartley, RC | 1 |
| Eaton, S | 1 |
| Costa, ASH | 1 |
| Brookes, PS | 1 |
| Davidson, SM | 1 |
| Duchen, MR | 1 |
| Saeb-Parsy, K | 1 |
| Shattock, MJ | 1 |
| Robinson, AJ | 1 |
| Work, LM | 1 |
| Frezza, C | 1 |
| Krieg, T | 1 |
| Murphy, MP | 1 |
| de La Paz, LD | 1 |
| Lezama, R | 1 |
| Torres-Marquez, ME | 1 |
| Pasantes-Morales, H | 1 |
| Bui, BV | 1 |
| Vingrys, AJ | 1 |
| Kalloniatis, M | 1 |
| King, N | 1 |
| Lin, H | 1 |
| McGivan, JD | 1 |
| Suleiman, MS | 1 |
| Drognitz, O | 1 |
| Obermaier, R | 1 |
| Liu, X | 1 |
| Neeff, H | 1 |
| von Dobschuetz, E | 1 |
| Hopt, UT | 1 |
| Benz, S | 1 |
| Büyükuysal, RL | 1 |
| Uckermann, O | 1 |
| Vargová, L | 1 |
| Ulbricht, E | 1 |
| Klaus, C | 1 |
| Weick, M | 1 |
| Rillich, K | 1 |
| Wiedemann, P | 1 |
| Reichenbach, A | 1 |
| Syková, E | 1 |
| Bringmann, A | 1 |
| Zhou, L | 1 |
| Stanley, WC | 1 |
| Saidel, GM | 1 |
| Yu, X | 1 |
| Cabrera, ME | 1 |
| Xu, L | 1 |
| Dayal, M | 1 |
| Ouyang, YB | 1 |
| Sun, Y | 1 |
| Yang, CF | 1 |
| Frydman, J | 1 |
| Giffard, RG | 1 |
| Pisarenko, OI | 1 |
| Shul'zhenko, VS | 1 |
| Studneva, IM | 1 |
| Berger, K | 1 |
| Stögbauer, F | 1 |
| Stoll, M | 1 |
| Wellmann, J | 1 |
| Huge, A | 1 |
| Cheng, S | 1 |
| Kessler, C | 1 |
| John, U | 1 |
| Assmann, G | 1 |
| Ringelstein, EB | 1 |
| Funke, H | 1 |
| Rokkas, CK | 2 |
| Cronin, CS | 1 |
| Nitta, T | 1 |
| Helfrich, LR | 2 |
| Lobner, DC | 2 |
| Choi, DW | 2 |
| Kouchoukos, NT | 2 |
| Sijens, PE | 1 |
| van Dijk, P | 1 |
| Oudkerk, M | 1 |
| Delbarre, B | 1 |
| Delbarre, G | 1 |
| Calinon, F | 1 |
| Allen, BT | 1 |
| Davis, CG | 1 |
| Osborne, D | 1 |
| Karl, I | 1 |
| O'Neill, CM | 2 |
| Ball, SG | 2 |
| Vaughan, PF | 2 |
| Ogata, T | 1 |
| Nakamura, Y | 1 |
| Tsuji, K | 1 |
| Okumura, H | 1 |
| Kataoka, K | 1 |
| Shibata, T | 1 |
| El Tamer, A | 1 |
| Prokopenko, I | 1 |
| Wülfert, E | 1 |
| Hanin, I | 1 |
| Töns, C | 1 |
| Klosterhalfen, B | 1 |
| Klein, HM | 1 |
| Rau, HM | 1 |
| Anurov, M | 1 |
| Oettinger, A | 1 |
| Schumpelick, V | 1 |
| Kimura, M | 1 |
| Sawada, K | 1 |
| Miyagawa, T | 1 |
| Kuwada, M | 1 |
| Katayama, K | 1 |
| Nishizawa, Y | 1 |
| Defraigne, JO | 1 |
| Limet, R | 1 |
| Tobinaga, S | 1 |
| Rego, AC | 1 |
| Agostinho, P | 1 |
| Melo, J | 1 |
| Cunha, RA | 1 |
| Oliveira, CR | 1 |
| Donello, JE | 1 |
| Padillo, EU | 1 |
| Webster, ML | 1 |
| Wheeler, LA | 1 |
| Gil, DW | 1 |
| Barnett, NL | 1 |
| Pow, DV | 1 |
| Bull, ND | 1 |
| Oja, SS | 1 |
| Saransaari, P | 1 |
| Garcia, JH | 1 |
| Lossinsky, AS | 1 |
| Kauffman, FC | 1 |
| Conger, KA | 1 |
| Isselhard, W | 1 |
| Schorn, B | 1 |
| Uekermann, U | 1 |
| Hügel, W | 1 |
| Kupcsulik, P | 1 |
| Kokas, P | 1 |
| de Graaf, AA | 1 |
| Bovée, WM | 1 |
| Yum, SW | 1 |
| Faden, AI | 1 |
| Kehrer, G | 1 |
| Blech, M | 1 |
| Kallerhoff, M | 1 |
| Langheinrich, M | 1 |
| Bretschneider, HJ | 1 |
| Bresnick, GH | 1 |
| Martiniak, J | 2 |
| Chavko, M | 2 |
| Danielisová, V | 1 |
| Marsala, J | 2 |
| Lehmann, A | 1 |
| Hagberg, H | 1 |
| Nyström, B | 1 |
| Sandberg, M | 1 |
| Hamberger, A | 1 |
| Folbergrová, J | 1 |
| Ljunggren, B | 1 |
| Norberg, K | 1 |
| Siesjö, BK | 1 |
| Brosnan, JT | 1 |
| Krebs, HA | 1 |
| Williamson, DH | 1 |
| Kirsch, U | 1 |
| Rodewald, G | 1 |
| Kalmár, P | 1 |
| Mendler, N | 1 |
| Hagl, S | 1 |
| Sebening, F | 1 |
| Theobald, KP | 1 |
| Kononova, NS | 1 |
2 reviews available for aspartic acid and Ischemia
| Article | Year |
|---|---|
Excitotoxins: a possible new mechanism for the pathogenesis of ischemic retinal damage.
Topics: Adult; Animals; Aspartic Acid; Cats; Cells, Cultured; Glutamates; Humans; Ischemia; Mice; Neurons; N | 1989 |
In vivo regulation of extracellular taurine and other neuroactive amino acids in the rabbit hippocampus.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Ethanolamines; Extracellular Space; Hippocampus; Iodoa | 1985 |
43 other studies available for aspartic acid and Ischemia
| Article | Year |
|---|---|
Impairment of neuronal glutamate uptake and modulation of the glutamate transporter GLT-1 induced by retinal ischemia.
Topics: Animals; Aspartic Acid; Biological Transport; Excitatory Amino Acid Transporter 1; Excitatory Amino | 2013 |
Electrophysiological and metabolic effects of CHF5074 in the hippocampus: protection against in vitro ischemia.
Topics: Acetates; Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Cells, Cultured; | 2014 |
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Topics: Adenosine Monophosphate; Animals; Aspartic Acid; Citric Acid Cycle; Disease Models, Animal; Electron | 2014 |
Tyrosine kinases and amino acid efflux under hyposmotic and ischaemic conditions in the chicken retina.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acids; Animals; Aspartic Acid; Chickens; Chl | 2002 |
Correlating retinal function and amino acid immunocytochemistry following post-mortem ischemia.
Topics: Animals; Aspartic Acid; Electroretinography; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Immuno | 2003 |
Aspartate transporter expression and activity in hypertrophic rat heart and ischaemia-reperfusion injury.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting, | 2004 |
Effects of organ preservation, ischemia time and caspase inhibition on apoptosis and microcirculation in rat pancreas transplantation.
Topics: Animals; Apoptosis; Aspartic Acid; Capillaries; Caspase Inhibitors; DNA Fragmentation; Endothelium, | 2004 |
Ischemia and reoxygenation induced amino acid release release and tissue damage in the slices of rat corpus striatum.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Calcium; Citrulline; Corpus Striatum; Female; gamma-Amin | 2004 |
Glutamate-evoked alterations of glial and neuronal cell morphology in the guinea pig retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxa | 2004 |
Regulation of lactate production at the onset of ischaemia is independent of mitochondrial NADH/NAD+: insights from in silico studies.
Topics: Animals; Aspartic Acid; Computer Simulation; Cytosol; Energy Metabolism; Glycolysis; Humans; Ischemi | 2005 |
Chaperonin GroEL and its mutant D87K protect from ischemia in vivo and in vitro.
Topics: Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Blotting, Western; Brain | 2006 |
Efficiency of cardioplegic solutions containing L-arginine and L-aspartic acid.
Topics: Adenosine Triphosphate; Animals; Arginine; Aspartic Acid; Blood Pressure; Cardioplegic Solutions; Ca | 2006 |
The glu298asp polymorphism in the nitric oxide synthase 3 gene is associated with the risk of ischemic stroke in two large independent case-control studies.
Topics: Aged; Aspartic Acid; Case-Control Studies; Female; Glutamic Acid; Humans; Integrin alpha2; Interleuk | 2007 |
Profound systemic hypothermia inhibits the release of neurotransmitter amino acids in spinal cord ischemia.
Topics: Analysis of Variance; Animals; Aspartic Acid; Cardiopulmonary Bypass; Disease Models, Animal; Evoked | 1995 |
Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma.
Topics: Adult; Aspartic Acid; Brain Neoplasms; Breast Neoplasms; Carcinoma; Choline; Contrast Media; Creatin | 1994 |
Action of trimetazidine on retina of gerbils after ischemia reperfusion insult: determination of .OH, amino acids, and electroretinogram.
Topics: Amino Acids; Animals; Aspartic Acid; Electroretinography; Female; gamma-Aminobutyric Acid; Gentisate | 1994 |
Spinal cord ischemia and reperfusion metabolism: the effect of hypothermia.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Body Temperature; Combined Modality Therapy; Energy | 1994 |
Effects of ischaemic conditions on uptake of glutamate, aspartate, and noradrenaline by cell lines derived from the human nervous system.
Topics: Aspartic Acid; Astrocytoma; Biological Transport; Cell Hypoxia; Cell Line; Glutamates; Glutamic Acid | 1994 |
Dextrorphan inhibits the release of excitatory amino acids during spinal cord ischemia.
Topics: Amino Acids; Animals; Aspartic Acid; Dextrorphan; Evoked Potentials; Evoked Potentials, Somatosensor | 1994 |
Role of aspartate in ischemic spinal cord damage.
Topics: Animals; Aspartic Acid; Calcium; Cell Death; Cell Hypoxia; Cells, Cultured; Excitatory Amino Acids; | 1996 |
Mivazerol, a novel alpha2-agonist and potential anti-ischemic drug, inhibits KC1-stimulated neurotransmitter release in rat nervous tissue preparations.
Topics: Adrenergic alpha-Agonists; Animals; Aspartic Acid; Brain Stem; Clonidine; Glutamates; Hippocampus; I | 1996 |
Induction of heat shock protein 70 (HSP70) by zinc bis (DL-hydrogen aspartate) reduces ischemic small-bowel tissue damage in rats.
Topics: Animals; Aspartic Acid; HSP70 Heat-Shock Proteins; Injections, Intraperitoneal; Intestinal Mucosa; I | 1997 |
Role of glutamate receptors and voltage-dependent calcium and sodium channels in the extracellular glutamate/aspartate accumulation and subsequent neuronal injury induced by oxygen/glucose deprivation in cultured hippocampal neurons.
Topics: Animals; Aspartic Acid; Calcium Channel Blockers; Cell Hypoxia; Cells, Cultured; Excitatory Amino Ac | 1998 |
[From the study of biochemical changes in ischemic and reperfused skeletal muscle to the controlled reperfusion of limbs in patients with acute severe ischemia].
Topics: Acute Disease; Aged; Aged, 80 and over; Alkalies; Aspartic Acid; Biochemical Phenomena; Biochemistry | 1998 |
Spinal cord protection: effect of N-methyl-D-aspartate receptor antagonist MK-801 for spinal cord ischemia in a rabbit model.
Topics: Animals; Aspartic Acid; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Ische | 2000 |
Adenosine A2A receptors regulate the extracellular accumulation of excitatory amino acids upon metabolic dysfunction in chick cultured retinal cells.
Topics: Adenosine; Analysis of Variance; Animals; Aspartic Acid; Bicuculline; Cells, Cultured; Chick Embryo; | 2000 |
alpha(2)-Adrenoceptor agonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischemia.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anima | 2001 |
Differential perturbation of neuronal and glial glutamate transport systems in retinal ischaemia.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Biological Transport, Active; Electroretin | 2001 |
Transport of D-aspartate in cerebellar granule cells under cell-damaging conditions.
Topics: Animals; Antimetabolites; Aspartic Acid; Cell Hypoxia; Cells, Cultured; Cerebellum; Cerebrovascular | 2001 |
Neuronal ischemic injury: light microscopy, ultrastructure and biochemistry.
Topics: Alanine; Animals; Aspartic Acid; Brain; Brain Chemistry; Brain Death; Cats; Cell Survival; Cerebrova | 1978 |
[Myocardial metabolic status in various methods of inducing a reversible heart arrest].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Aspartic Acid; Dogs; Drug Combinations; Glycog | 1979 |
Ischemic damage of the liver. Part II: In vivo investigation of the prevention of the ischemic lesion of the liver.
Topics: Adenosine Triphosphate; Allopurinol; Animals; Aspartic Acid; Chlorides; Glucagon; Ischemia; Liver; L | 1979 |
Effects of ischaemic conditions on the uptake of catecholamine and amino acid neurotransmitters.
Topics: Aspartic Acid; Humans; Hypoxia; Ischemia; Neurons; Neurotransmitter Agents; Norepinephrine; Tumor Ce | 1990 |
Improved quantification of in vivo 1H NMR spectra by optimization of signal acquisition and processing and by incorporation of prior knowledge into the spectral fitting.
Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Cerebral Cortex; Glutamates; Glutamic Acid; Glutamin | 1990 |
Comparison of the neuroprotective effects of the N-methyl-D-aspartate antagonist MK-801 and the opiate-receptor antagonist nalmefene in experimental spinal cord ischemia.
Topics: Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Humans; Ischemia; Male; N-Methyla | 1990 |
Contribution of amino acids in protective solutions to postischemic functional recovery of canine kidneys.
Topics: Animals; Aorta; Aspartic Acid; Diuresis; Dogs; Female; Glomerular Filtration Rate; Glucose; Histidin | 1989 |
Regional concentrations of transmitter amino acids after spinal cord ischaemia in the rabbit.
Topics: Amino Acids; Animals; Aspartic Acid; Female; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine | 1989 |
Free amino acids in the spinal cord and ganglia of dogs after ligation of the abdominal aorta.
Topics: Alanine; Amino Acids; Animals; Aorta, Abdominal; Aspartic Acid; Dogs; Female; Ganglia, Spinal; Gluta | 1985 |
Influence of complete ischemia on glycolytic metabolites, citric acid cycle intermediates, and associated amino acids in the rat cerebral cortex.
Topics: Acetone; Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Brain Chemistry; Cerebral Cortex; | 1974 |
Effects of ischaemia on metabolite concentrations in rat liver.
Topics: Acetoacetates; Adenine Nucleotides; Alanine; Ammonia; Animals; Aspartic Acid; Cycloserine; Freezing; | 1970 |
Induced ischemic arrest. Clinical experience with cardioplegia in open-heart surgery.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aspartic Acid; Child; Child, Preschool; Female; Heart Arr | 1972 |
[Substrates of energy metabolism in parabiotically perfused rat hearts during and after cardioplegy by ischemia, potassium chloride and potassium-magnesium-aspartate].
Topics: Adenine Nucleotides; Animals; Aspartic Acid; Heart Arrest; Ischemia; Lactates; Magnesium; Male; Myoc | 1972 |
[Nitrogen metabolism in the kidneys during peripheral circulatory disorders in a limb].
Topics: Amides; Ammonia; Animals; Arteries; Aspartic Acid; Dicarboxylic Acids; Glutamates; Glutamine; Hindli | 1967 |