Page last updated: 2024-11-08

aspartic acid and Hypoxia-Ischemia, Brain

aspartic acid has been researched along with Hypoxia-Ischemia, Brain in 41 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.

Research Excerpts

ExcerptRelevanceReference
" Our aim was to use magnetic resonance spectroscopy (MRS) biomarkers and immunohistochemistry to investigate the cerebral effects of the NHE inhibitor, methyl isobutyl amiloride (MIA) given after severe perinatal asphyxia in the piglet."7.79Methyl-isobutyl amiloride reduces brain Lac/NAA, cell death and microglial activation in a perinatal asphyxia model. ( Bainbridge, A; Cady, E; Chandrasekaran, M; Cheong, J; Faulkner, S; Hristova, M; Iwata, O; Iwata, S; Kapetanakis, A; Kato, T; Raivich, G; Robertson, NJ, 2013)
" Our aim was to use magnetic resonance spectroscopy (MRS) biomarkers and immunohistochemistry to investigate the cerebral effects of the NHE inhibitor, methyl isobutyl amiloride (MIA) given after severe perinatal asphyxia in the piglet."3.79Methyl-isobutyl amiloride reduces brain Lac/NAA, cell death and microglial activation in a perinatal asphyxia model. ( Bainbridge, A; Cady, E; Chandrasekaran, M; Cheong, J; Faulkner, S; Hristova, M; Iwata, O; Iwata, S; Kapetanakis, A; Kato, T; Raivich, G; Robertson, NJ, 2013)
"CSF glycine value was related to erythrocyte count, and CSF taurine value was related to its plasmatic level."2.69Glycine and other neurotransmitter amino acids in cerebrospinal fluid in perinatal asphyxia and neonatal hypoxic-ischaemic encephalopathy. ( Deulofeu, R; Figueras-Aloy, J; Jiménez, R; Roldán, A, 1999)
"These four children all had seizure activity and abnormal initial neurological examinations and required admission to the PICU."1.33Elevated lactate as an early marker of brain injury in inflicted traumatic brain injury. ( Ball, WS; Care, M; Cecil, KM; Makoroff, KL, 2005)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (4.88)18.2507
2000's17 (41.46)29.6817
2010's19 (46.34)24.3611
2020's3 (7.32)2.80

Authors

AuthorsStudies
Barta, H2
Jermendy, A2
Kovacs, L1
Schiever, N1
Rudas, G2
Szabo, M2
Lee, JW1
Sreepada, LP1
Bevers, MB1
Li, K1
Scirica, BM1
Santana da Silva, D1
Henderson, GV1
Bay, C1
Lin, AP1
Kyng, KJ1
Kerrn-Jespersen, S1
Bennedsgaard, K1
Skajaa, T1
Pedersen, M1
Holm, IE1
Henriksen, TB1
Mitra, S2
Bale, G2
Highton, D1
Gunny, R1
Uria-Avellanal, C2
Bainbridge, A6
Sokolska, M1
Price, D2
Huertas-Ceballos, A1
Kendall, GS1
Meek, J2
Tachtsidis, I4
Robertson, NJ8
Crespo-Eguilaz, N1
Dominguez, PD1
Vaquero, M1
Narbona, J1
Shibasaki, J1
Aida, N1
Morisaki, N1
Tomiyasu, M1
Nishi, Y1
Toyoshima, K1
Kolossvary, M1
Kozak, LR1
Lakatos, A1
Meder, U1
Lally, PJ1
Montaldo, P1
Oliveira, V1
Soe, A1
Swamy, R1
Bassett, P1
Mendoza, J1
Atreja, G1
Kariholu, U1
Pattnayak, S1
Sashikumar, P1
Harizaj, H1
Mitchell, M1
Ganesh, V1
Harigopal, S1
Dixon, J1
English, P1
Clarke, P1
Muthukumar, P1
Satodia, P1
Wayte, S1
Abernethy, LJ1
Yajamanyam, K1
Huertas, A1
Sharp, DJ1
Kalra, V1
Chawla, S1
Shankaran, S1
Thayyil, S3
Oliva, I1
Fernández, M1
Martín, ED1
Brandão, LA1
Caires, C1
Seo, H1
Lim, KH2
Choi, JH1
Jeong, SM1
Goergen, SK1
Ang, H1
Wong, F1
Carse, EA1
Charlton, M1
Evans, R1
Whiteley, G1
Clark, J1
Shipp, D1
Jolley, D1
Paul, E1
Cheong, JL2
Cady, EB3
Raivich, G2
Ezzati, M2
Broad, KD2
Kawano, G2
Oliver-Taylor, A1
Rocha-Ferreira, E2
Alonso-Alconada, D2
Fierens, I2
Rostami, J1
Jane Hassell, K1
Gressens, P2
Hristova, M2
Bennett, K1
Lebon, S1
Fleiss, B2
Yellon, D1
Hausenloy, DJ1
Golay, X2
Hassell, J1
Ma, D1
Sanders, RD1
Baron, JC1
Munkeby, BH1
De Lange, C1
Emblem, KE1
Bjørnerud, A1
Kro, GA1
Andresen, J1
Winther-Larssen, EH1
Løberg, EM1
Hald, JK1
Chandrasekaran, M2
Taylor, A1
Chong, WK1
Murad, S1
Omar, RZ1
Azzopardi, D1
Edwards, AD1
Park, HK1
Seol, IJ1
Kim, KS2
Bonifacio, SL1
Saporta, A1
Glass, HC1
Lee, P1
Glidden, DV1
Ferriero, DM1
Barkovich, AJ1
Xu, D1
Jian, H1
Yi-Fang, W1
Qi, L1
Xiao-Song, H1
Gui-Yun, Z1
Kato, T1
Iwata, O1
Kapetanakis, A1
Faulkner, S1
Cheong, J1
Iwata, S1
Cady, E2
Brooks, KJ1
Hargreaves, I1
Bhakoo, K1
Sellwood, M1
O'Brien, F1
Noone, M1
Sakata, Y1
Wylezinska, M1
Thornton, J1
Ordidge, R1
Nguyen, Q1
Clemence, M1
Wyatt, J1
Bates, TE1
Fan, G1
Wu, Z1
Chen, L1
Guo, Q1
Ye, B1
Mao, J1
Wartenberg, KE1
Patsalides, A1
Yepes, MS1
Vial, F1
Serriere, S1
Barantin, L1
Montharu, J1
Nadal-Desbarats, L1
Pourcelot, L1
Seguin, F1
Vidwans, AS1
Hewett, SJ1
Makoroff, KL1
Cecil, KM1
Care, M1
Ball, WS1
Boichot, C1
Walker, PM1
Durand, C1
Grimaldi, M1
Chapuis, S1
Gouyon, JB1
Brunotte, F1
da Silva, LF1
Höefel Filho, JR1
Anés, M1
Nunes, ML1
Williams, JA1
Barreiro, CJ1
Nwakanma, LU1
Lange, MS1
Kratz, LE1
Blue, ME1
Berrong, J1
Patel, ND1
Gott, VL1
Troncoso, JC1
Johnston, MV1
Baumgartner, WA1
Penrice, J1
Wyatt, JS1
Cox, IJ1
Han, TR1
Chun, MH1
Jang, DH1
Cho, HJ1
Gwak, M1
Park, P1
Kim, K1
Lim, K1
Jeong, S1
Baek, C1
Lee, J1
Papazisis, G1
Pourzitaki, C1
Sardeli, C1
Lallas, A1
Amaniti, E1
Kouvelas, D1
Gücüyener, K1
Atalay, Y1
Aral, YZ1
Hasanoğlu, A1
Türkyilmaz, C1
Biberoglu, G1
Roldán, A1
Figueras-Aloy, J1
Deulofeu, R1
Jiménez, R1
Dawson, DA1
Wadsworth, G1
Palmer, AM1
Engidawork, E1
Loidl, F1
Chen, Y1
Kohlhauser, C1
Stoeckler, S1
Dell'Anna, E1
Lubec, B1
Lubec, G1
Goiny, M1
Gross, J1
Andersson, K1
Herrera-Marschitz, M1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Darbepoetin in Neonatal Encephalopathy (EDEN) Trial[NCT04432662]Phase 2150 participants (Anticipated)Interventional2021-05-28Recruiting
A Multicentre Prospective Study on Magnetic Resonance Biomarkers in Neonatal Encephalopathy[NCT01309711]180 participants (Anticipated)Observational2011-03-30Completed
Optimising the Duration of Cooling Therapy in Mild Neonatal Encephalopathy[NCT03409770]140 participants (Anticipated)Interventional2019-10-10Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for aspartic acid and Hypoxia-Ischemia, Brain

ArticleYear
Hypoxic-ischemic injuries: the role of magnetic resonance spectroscopy.
    Neuroimaging clinics of North America, 2013, Volume: 23, Issue:3

    Topics: Americas; Aspartic Acid; Biomarkers; Brain; Humans; Hypoxia-Ischemia, Brain; Lactic Acid; Magnetic R

2013
Magnetic resonance spectroscopy biomarkers in term perinatal asphyxial encephalopathy: from neuropathological correlates to future clinical applications.
    Current pediatric reviews, 2014, Volume: 10, Issue:1

    Topics: Animals; Animals, Newborn; Aspartic Acid; Asphyxia Neonatorum; Biomarkers; Choline; Creatine; Diseas

2014
Cerebral magnetic resonance biomarkers in neonatal encephalopathy: a meta-analysis.
    Pediatrics, 2010, Volume: 125, Issue:2

    Topics: Aspartic Acid; Basal Ganglia; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Lactates; Magnetic R

2010

Trials

3 trials available for aspartic acid and Hypoxia-Ischemia, Brain

ArticleYear
Therapeutic hypothermia for neonatal encephalopathy results in improved microstructure and metabolism in the deep gray nuclei.
    AJNR. American journal of neuroradiology, 2012, Volume: 33, Issue:11

    Topics: Aspartic Acid; Biomarkers; Brain Diseases, Metabolic, Inborn; Choline; Diffusion Magnetic Resonance

2012
Prognostic value of 1H-MRS in neonatal encephalopathy.
    Pediatric neurology, 2006, Volume: 34, Issue:5

    Topics: Apgar Score; Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Choline; Creatine; Creatinine; Femal

2006
Glycine and other neurotransmitter amino acids in cerebrospinal fluid in perinatal asphyxia and neonatal hypoxic-ischaemic encephalopathy.
    Acta paediatrica (Oslo, Norway : 1992), 1999, Volume: 88, Issue:10

    Topics: Analysis of Variance; Aspartic Acid; Asphyxia Neonatorum; Chi-Square Distribution; Chromatography, H

1999

Other Studies

35 other studies available for aspartic acid and Hypoxia-Ischemia, Brain

ArticleYear
Predictive performance and metabolite dynamics of proton MR spectroscopy in neonatal hypoxic-ischemic encephalopathy.
    Pediatric research, 2022, Volume: 91, Issue:3

    Topics: Aspartic Acid; Choline; Creatine; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Inositol; Proton

2022
Magnetic Resonance Spectroscopy of Hypoxic-Ischemic Encephalopathy After Cardiac Arrest.
    Neurology, 2022, 03-22, Volume: 98, Issue:12

    Topics: Aspartic Acid; Brain; Choline; Creatine; Heart Arrest; Humans; Hypoxia-Ischemia, Brain; Magnetic Res

2022
Short-term outcomes of remote ischemic postconditioning 1 h after perinatal hypoxia-ischemia in term piglets.
    Pediatric research, 2021, Volume: 89, Issue:1

    Topics: Animals; Animals, Newborn; Aspartic Acid; Biomarkers; Brain; Diffusion Magnetic Resonance Imaging; D

2021
Pressure passivity of cerebral mitochondrial metabolism is associated with poor outcome following perinatal hypoxic ischemic brain injury.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2019, Volume: 39, Issue:1

    Topics: Adenosine Triphosphate; Aspartic Acid; Blood Pressure; Brain; Cerebrovascular Circulation; Developme

2019
[Developmental amnesia and early brain damage: neuropsychology and neuroimaging].
    Revista de neurologia, 2018, Mar-01, Volume: 66, Issue:S01

    Topics: Adolescent; Amnesia; Aspartic Acid; Atrophy; Cerebral Palsy; Child; Choline; Creatine; Female; Fetal

2018
Changes in Brain Metabolite Concentrations after Neonatal Hypoxic-ischemic Encephalopathy.
    Radiology, 2018, Volume: 288, Issue:3

    Topics: Aspartic Acid; Creatine; Female; Glutamic Acid; Glutamine; Gray Matter; Humans; Hypoxia-Ischemia, Br

2018
Prognostic value of early, conventional proton magnetic resonance spectroscopy in cooled asphyxiated infants.
    BMC pediatrics, 2018, 09-15, Volume: 18, Issue:1

    Topics: Aspartic Acid; Brain; Creatine; Epilepsy; Female; Hearing Loss; Hospital Mortality; Humans; Hypother

2018
Magnetic resonance spectroscopy assessment of brain injury after moderate hypothermia in neonatal encephalopathy: a prospective multicentre cohort study.
    The Lancet. Neurology, 2019, Volume: 18, Issue:1

    Topics: Aspartic Acid; Brain; Female; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant; Infant,

2019
Magnetic resonance spectroscopy assessment of brain injury after moderate hypothermia in neonatal encephalopathy: a prospective multicentre cohort study.
    The Lancet. Neurology, 2019, Volume: 18, Issue:1

    Topics: Aspartic Acid; Brain; Female; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant; Infant,

2019
Magnetic resonance spectroscopy assessment of brain injury after moderate hypothermia in neonatal encephalopathy: a prospective multicentre cohort study.
    The Lancet. Neurology, 2019, Volume: 18, Issue:1

    Topics: Aspartic Acid; Brain; Female; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant; Infant,

2019
Magnetic resonance spectroscopy assessment of brain injury after moderate hypothermia in neonatal encephalopathy: a prospective multicentre cohort study.
    The Lancet. Neurology, 2019, Volume: 18, Issue:1

    Topics: Aspartic Acid; Brain; Female; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant; Infant,

2019
Dopamine release regulation by astrocytes during cerebral ischemia.
    Neurobiology of disease, 2013, Volume: 58

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Astrocytes; Calcium; Corpus Striatum;

2013
Similar neuroprotective effects of ischemic and hypoxic preconditioning on hypoxia-ischemia in the neonatal rat: a proton MRS study.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2013, Volume: 31, Issue:7

    Topics: Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Brain; Creatine; Hypoxia-Ischemia, B

2013
Early MRI in term infants with perinatal hypoxic-ischaemic brain injury: interobserver agreement and MRI predictors of outcome at 2 years.
    Clinical radiology, 2014, Volume: 69, Issue:1

    Topics: Aspartic Acid; Diffusion Magnetic Resonance Imaging; Female; Humans; Hypoxia-Ischemia, Brain; Infant

2014
Immediate remote ischemic postconditioning after hypoxia ischemia in piglets protects cerebral white matter but not grey matter.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2016, Volume: 36, Issue:8

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Aspartic Acid; Biomarkers; Brain Mapping; Disease

2016
Inhaled 45-50% argon augments hypothermic brain protection in a piglet model of perinatal asphyxia.
    Neurobiology of disease, 2016, Volume: 87

    Topics: Animals; Animals, Newborn; Argon; Aspartic Acid; Asphyxia Neonatorum; Blood Chemical Analysis; Blood

2016
Relationship Between Cerebral Oxygenation and Metabolism During Rewarming in Newborn Infants After Therapeutic Hypothermia Following Hypoxic-Ischemic Brain Injury.
    Advances in experimental medicine and biology, 2016, Volume: 923

    Topics: Aspartic Acid; Biomarkers; Body Temperature Regulation; Cerebrovascular Circulation; Electron Transp

2016
Metabolism of DWI lesions: implications for rescue therapy.
    International journal of stroke : official journal of the International Stroke Society, 2007, Volume: 2, Issue:4

    Topics: Acute Disease; Animals; Aspartic Acid; Cell Hypoxia; Cerebrovascular Circulation; Diffusion Magnetic

2007
A piglet model for detection of hypoxic-ischemic brain injury with magnetic resonance imaging.
    Acta radiologica (Stockholm, Sweden : 1987), 2008, Volume: 49, Issue:9

    Topics: Animals; Animals, Newborn; Aspartic Acid; Basal Ganglia; Brain; Brain Chemistry; Choline; Creatine;

2008
Magnetic resonance biomarkers of neuroprotective effects in infants with hypoxic ischemic encephalopathy.
    Seminars in fetal & neonatal medicine, 2010, Volume: 15, Issue:5

    Topics: Aspartic Acid; Asphyxia Neonatorum; Biomarkers; Brain; Humans; Hypoxia-Ischemia, Brain; Image Proces

2010
Protective effect of hypoxic preconditioning on hypoxic-ischemic injured newborn rats.
    Journal of Korean medical science, 2011, Volume: 26, Issue:11

    Topics: Animals; Animals, Newborn; Apoptosis; Aspartic Acid; Brain; Carotid Arteries; Creatine; Hypoxia-Isch

2011
Cerebral blood flow and metabolic changes in hippocampal regions of a modified rat model with chronic cerebral hypoperfusion.
    Acta neurologica Belgica, 2013, Volume: 113, Issue:3

    Topics: Animals; Aspartic Acid; Cerebrovascular Circulation; Creatine; Disease Models, Animal; Hippocampus;

2013
Methyl-isobutyl amiloride reduces brain Lac/NAA, cell death and microglial activation in a perinatal asphyxia model.
    Journal of neurochemistry, 2013, Volume: 124, Issue:5

    Topics: Amiloride; Animals; Aspartic Acid; Asphyxia; Brain; Cell Death; Disease Models, Animal; Hypoxia-Isch

2013
Delayed hypothermia prevents decreases in N-acetylaspartate and reduced glutathione in the cerebral cortex of the neonatal pig following transient hypoxia-ischaemia.
    Neurochemical research, 2002, Volume: 27, Issue:12

    Topics: Animals; Animals, Newborn; Aspartic Acid; Cerebral Cortex; Citrate (si)-Synthase; Glutathione; Hypot

2002
Hypoxia-ischemic encephalopathy in full-term neonate: correlation proton MR spectroscopy with MR imaging.
    European journal of radiology, 2003, Volume: 45, Issue:2

    Topics: Apgar Score; Aspartic Acid; Basal Ganglia; Female; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn;

2003
Is magnetic resonance spectroscopy superior to conventional diagnostic tools in hypoxic-ischemic encephalopathy?
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2004, Volume: 14, Issue:2

    Topics: Aspartic Acid; Brain; Brain Death; Cell Death; Choline; Coma; Creatine; Diffusion Magnetic Resonance

2004
A newborn piglet study of moderate hypoxic-ischemic brain injury by 1H-MRS and MRI.
    Magnetic resonance imaging, 2004, Volume: 22, Issue:4

    Topics: Animals; Animals, Newborn; Aspartic Acid; Basal Ganglia; Cerebral Cortex; Cerebrovascular Circulatio

2004
Enhanced release of synaptic glutamate underlies the potentiation of oxygen-glucose deprivation-induced neuronal injury after induction of NOS-2.
    Experimental neurology, 2004, Volume: 190, Issue:1

    Topics: Animals; Aspartic Acid; Cell Death; Cell Hypoxia; Cells, Cultured; Dose-Response Relationship, Drug;

2004
Elevated lactate as an early marker of brain injury in inflicted traumatic brain injury.
    Pediatric radiology, 2005, Volume: 35, Issue:7

    Topics: Aspartic Acid; Brain Chemistry; Brain Injuries; Critical Care; Female; Fractures, Bone; Frontal Lobe

2005
Term neonate prognoses after perinatal asphyxia: contributions of MR imaging, MR spectroscopy, relaxation times, and apparent diffusion coefficients.
    Radiology, 2006, Volume: 239, Issue:3

    Topics: Age Factors; Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Brain Edema; Cause of Death; Cerebra

2006
Valproic acid prevents brain injury in a canine model of hypothermic circulatory arrest: a promising new approach to neuroprotection during cardiac surgery.
    The Annals of thoracic surgery, 2006, Volume: 81, Issue:6

    Topics: Animals; Apoptosis; Aspartic Acid; Behavior, Animal; Biomarkers; Brain; Brain Chemistry; Brain Damag

2006
Proton MR spectroscopy in neonates with perinatal cerebral hypoxic-ischemic injury: metabolite peak-area ratios, relaxation times, and absolute concentrations.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:7

    Topics: Aspartic Acid; Birth Injuries; Body Water; Brain; Brain Chemistry; Child Development; Choline; Creat

2006
Neuroprotective effects of growth hormone against hypoxic-ischemic brain injury in neonatal rats: 1H magnetic resonance spectroscopic study.
    Journal of Korean medical science, 2007, Volume: 22, Issue:1

    Topics: Animals; Animals, Newborn; Aspartic Acid; Creatinine; Growth Hormone; Hypoxia-Ischemia, Brain; Lipid

2007
The effects of dantrolene on hypoxic-ischemic injury in the neonatal rat brain.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:1

    Topics: Animals; Animals, Newborn; Apoptosis; Aspartic Acid; Brain; Carotid Artery, Common; Creatine; Dantro

2008
Deferoxamine decreases the excitatory amino acid levels and improves the histological outcome in the hippocampus of neonatal rats after hypoxia-ischemia.
    Pharmacological research, 2008, Volume: 57, Issue:1

    Topics: Animals; Animals, Newborn; Aspartic Acid; Deferoxamine; Excitatory Amino Acids; Female; Glutamic Aci

2008
Excitatory amino acids and taurine levels in cerebrospinal fluid of hypoxic ischemic encephalopathy in newborn.
    Clinical neurology and neurosurgery, 1999, Volume: 101, Issue:3

    Topics: Aspartic Acid; Asphyxia Neonatorum; Case-Control Studies; Excitatory Amino Acids; Female; Follow-Up

1999
A comparative assessment of the efficacy and side-effect liability of neuroprotective compounds in experimental stroke.
    Brain research, 2001, Feb-23, Volume: 892, Issue:2

    Topics: Animals; Aspartic Acid; Extracellular Space; Glutamic Acid; Hypoxia-Ischemia, Brain; Male; Mice; Mic

2001
Comparison between hypothermia and glutamate antagonism treatments on the immediate outcome of perinatal asphyxia.
    Experimental brain research, 2001, Volume: 138, Issue:3

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Aspartic Acid; Asphyxia Neonatorum; Behavior, Ani

2001