Page last updated: 2024-11-08

aspartic acid and Heroin Dependence

aspartic acid has been researched along with Heroin Dependence in 4 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Heroin Dependence: Strong dependence or addiction, both physiological and emotional, upon HEROIN.

Research Excerpts

ExcerptRelevanceReference
"(1) Methadone was associated with normalisation of dorsal ACC biochemistry (increased N-acetylaspartate and glutamate/glutamine levels, and decreased myo-inositol levels) in a dose-dependent manner; (2) buprenorphine-treated individuals had higher myo-inositol and glutamate/glutamine levels than methadone-treated patients in the right dorsal ACC; and (3) myo-inositol levels were positively correlated with depressive symptoms in participants stabilised on buprenorphine."2.78Cingulate biochemistry in heroin users on substitution pharmacotherapy. ( Bora, E; Lubman, DI; MacKenzie, T; Roffel, K; Verdejo-García, A; Vilar-López, R; Yücel, M, 2013)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shen, HW1
Scofield, MD1
Boger, H1
Hensley, M1
Kalivas, PW1
Frischknecht, U1
Hermann, D1
Heinrich, M1
Hoerst, M1
Weber-Fahr, W1
Vollstädt-Klein, S1
Kiefer, F1
Mann, K1
Ende, G1
Verdejo-García, A1
Lubman, DI1
Roffel, K1
Vilar-López, R1
Bora, E1
MacKenzie, T1
Yücel, M1
Haselhorst, R1
Dürsteler-MacFarland, KM1
Scheffler, K1
Ladewig, D1
Müller-Spahn, F1
Stohler, R1
Seelig, J1
Seifritz, E1

Trials

1 trial available for aspartic acid and Heroin Dependence

ArticleYear
Cingulate biochemistry in heroin users on substitution pharmacotherapy.
    The Australian and New Zealand journal of psychiatry, 2013, Volume: 47, Issue:3

    Topics: Adult; Aspartic Acid; Buprenorphine; Depression; Dose-Response Relationship, Drug; Female; Functiona

2013

Other Studies

3 other studies available for aspartic acid and Heroin Dependence

ArticleYear
Synaptic glutamate spillover due to impaired glutamate uptake mediates heroin relapse.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Apr-16, Volume: 34, Issue:16

    Topics: Animals; Aspartic Acid; Ceftriaxone; Conditioning, Operant; Disease Models, Animal; Down-Regulation;

2014
Experience of social discrimination correlates with neurometabolism: a pilot study in heroin addicts.
    European archives of psychiatry and clinical neuroscience, 2013, Volume: 263, Issue:3

    Topics: Adult; Aspartic Acid; Female; Gyrus Cinguli; Heroin Dependence; Humans; Linear Models; Magnetic Reso

2013
Frontocortical N-acetylaspartate reduction associated with long-term i.v. heroin use.
    Neurology, 2002, Jan-22, Volume: 58, Issue:2

    Topics: Adult; Aspartic Acid; Female; Frontal Lobe; Heroin Dependence; Humans; Magnetic Resonance Spectrosco

2002