aspartic acid has been researched along with Hepatic Encephalopathy in 56 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We measured the brain uptake index (BUI) for radiolabelled L-ornithine (ORN) in rats with acute hepatic encephalopathy (HE) induced by two (onset stage) or three (comatous stage) administrations of a hepatotoxin-thioacetamide (TAA)." | 7.69 | Increase of the brain uptake index for L-ornithine in rats with hepatic encephalopathy. ( Albrecht, J; Hilgier, W; Januszewski, S; Kapuściński, A; Quack, G, 1994) |
| "Asymmetric dimethylarginine (ADMA) is an inhibitor of nitric oxide synthase that accumulates in liver disease and may contribute to hepatic encephalopathy (HE)." | 3.79 | Asymmetric dimethylarginine is strongly associated with cognitive dysfunction and brain MR spectroscopic abnormalities in cirrhosis. ( Ahluwalia, V; Bajaj, JS; Bouneva, I; Fuchs, M; Gilles, H; Heuman, DM; Kraft, KA; Luketic, V; Monteith, P; Noble, NA; Puri, P; Sanyal, AJ; Sterling, RK; Stravitz, RT; Wade, JB; White, MB, 2013) |
| " Among a number of clinical and laboratory variables analyzed, the only independent predictive factors of overt HE were hyponatremia (serum sodium < 130 mEq / l), history of overt HE, serum bilirubin,and serum creatinine." | 3.75 | Hyponatremia is a risk factor of hepatic encephalopathy in patients with cirrhosis: a prospective study with time-dependent analysis. ( Arroyo, V; Baccaro, ME; Ginès, P; Gómez-Ansón, B; Guevara, M; Martín-Llahí, M; Monté-Rubio, GC; Rami, L; Ríos, J; Torre, A; Torres, F, 2009) |
| "Rats were treated with a hepatotoxin thioacetamide (TAA) and examined 21 days later, when they showed moderate fatty metamorphosis of the liver and morphological changes in brain indicative of excitotoxic neuronal damage, but no evident biochemical or neurophysiological symptoms of hepatic encephalopathy (HE)." | 3.70 | Changes in the extracellular profiles of neuroactive amino acids in the rat striatum at the asymptomatic stage of hepatic failure. ( Albrecht, J; Borkowska, HD; Gadamski, R; Hilgier, W; Oja, SS; Saransaari, P; Walski, M; Zielińska, M, 1999) |
| " Decreased myo-inositol and increased glutamine levels were noted to be the most sensitive spectroscopic markers for cirrhotic patients with hepatic encephalopathy (HE)." | 3.70 | Proton magnetic resonance spectroscopy (1H-MRS) findings for the brain in patients with liver cirrhosis reflect the hepatic functional reserve. ( Kim, ST; Lee, JH; Lee, YS; Lim, TH; Min, YI; Mun, CW; Seo, DW; Suh, DJ, 1999) |
| "We measured the brain uptake index (BUI) for radiolabelled L-ornithine (ORN) in rats with acute hepatic encephalopathy (HE) induced by two (onset stage) or three (comatous stage) administrations of a hepatotoxin-thioacetamide (TAA)." | 3.69 | Increase of the brain uptake index for L-ornithine in rats with hepatic encephalopathy. ( Albrecht, J; Hilgier, W; Januszewski, S; Kapuściński, A; Quack, G, 1994) |
| "The calcium-dependent, high (65 mM) potassium-evoked release of the L-glutamate analogue [3H]D-aspartate (D-Asp) was measured in hippocampal slices derived from rats with (a) hepatic encephalopathy (HE) induced with a hepatotoxin, thioacetamide, (b) hyperammonemia produced by i." | 3.68 | Decreased potassium-stimulated release of [3H]D-aspartate from hippocampal slices distinguishes encephalopathy related to acute liver failure from that induced by simple hyperammonemia. ( Albrecht, J; Haugvicova, R; Hilgier, W, 1991) |
| "Brain alterations such as hepatic encephalopathy or brain edema are usually associated with liver failure." | 2.50 | Magnetic resonance of the brain in chronic and acute liver failure. ( Chavarria, L; Cordoba, J, 2014) |
| "Acute-on-chronic liver failure (ACLF), acute liver failure (ALF) and chronic liver disease (CLD) are common forms of liver failure and present with similar clinical profiles." | 1.35 | In vivo 1H magnetic resonance spectroscopy-derived metabolite variations between acute-on-chronic liver failure and acute liver failure. ( Gupta, RK; Nath, K; Radha Krishna, Y; Saraswat, VA; Thomas, MA; Verma, A, 2008) |
| "Minimal hepatic encephalopathy (MHE) is frequently diagnosed in patients with liver cirrhosis who do not show overt clinical cirrhosis-associated neurological deficits." | 1.33 | Chemical shift magnetic resonance spectroscopy of cingulate grey matter in patients with minimal hepatic encephalopathy. ( Graziadei, IW; Hinterhuber, H; Kugener, A; Marksteiner, J; Mattedi, M; Mechtcheriakov, S; Schocke, M; Vogel, W, 2005) |
| "Hepatic encephalopathy is a common problem in cirrhosis." | 1.30 | Cerebral abnormalities in patients with cirrhosis detected by proton magnetic resonance spectroscopy and magnetic resonance imaging. ( Andus, T; Feuerbach, S; Fründ, R; Geissler, A; Held, P; Hollerbach, S; Holstege, A; Lock, G; Schölmerich, J, 1997) |
| "Also, patients with Wilson disease and portosystemic shunting had lower myo-inositol-creatine ratios than did patients with Wilson disease and no portosystemic shunting (P < ." | 1.30 | Differentiation between portal-systemic encephalopathy and neurodegenerative disorders in patients with Wilson disease: H-1 MR spectroscopy. ( Hoogenraad, TU; Mali, WP; Van Den Heuvel, AG; Van der Grond, J; Van Rooij, LG; Van Wassenaer-van Hall, HN, 1997) |
| "All animals were tested three times for seizure threshold, and were then decapitated and the brains removed for analysis of the amino acids." | 1.30 | Effects of ammonia on pentylenetetrazole-induced seizure threshold. ( Arikan, K; Coskun, T; Guvener, B; Oran, O, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (33.93) | 18.7374 |
| 1990's | 14 (25.00) | 18.2507 |
| 2000's | 7 (12.50) | 29.6817 |
| 2010's | 8 (14.29) | 24.3611 |
| 2020's | 8 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Jain, A | 1 |
| Sharma, BC | 2 |
| Mahajan, B | 1 |
| Srivastava, S | 1 |
| Kumar, A | 1 |
| Sachdeva, S | 1 |
| Sonika, U | 1 |
| Dalal, A | 1 |
| Ridola, L | 1 |
| Nardelli, S | 1 |
| Gioia, S | 1 |
| Faccioli, J | 1 |
| Riggio, O | 1 |
| Labenz, C | 1 |
| Labenz, J | 1 |
| Galle, PR | 1 |
| Kovalic, AJ | 1 |
| Lee, TP | 1 |
| Da, BL | 1 |
| Liu, XF | 2 |
| Lu, JJ | 2 |
| Li, Y | 2 |
| Yang, XY | 2 |
| Qiang, JW | 2 |
| Asaki, Y | 1 |
| Murofushi, Y | 1 |
| Yasukawa, K | 1 |
| Hara, M | 1 |
| Takanashi, JI | 1 |
| Amodio, P | 1 |
| Ampuero, J | 1 |
| Rathi, S | 1 |
| Taneja, S | 1 |
| Sidhu, SS | 1 |
| Goyal, O | 1 |
| Kishore, H | 1 |
| Kaur, N | 1 |
| Sahinturk, H | 1 |
| Ozdemirkan, A | 1 |
| Zeyneloglu, P | 1 |
| Torgay, A | 1 |
| Pirat, A | 1 |
| Haberal, M | 1 |
| Chavarria, L | 2 |
| Cordoba, J | 2 |
| Meng, LP | 1 |
| Chen, YC | 1 |
| Li, YH | 1 |
| Zhu, JS | 1 |
| Ye, JL | 1 |
| Guevara, M | 1 |
| Baccaro, ME | 1 |
| Torre, A | 1 |
| Gómez-Ansón, B | 1 |
| Ríos, J | 1 |
| Torres, F | 1 |
| Rami, L | 1 |
| Monté-Rubio, GC | 1 |
| Martín-Llahí, M | 1 |
| Arroyo, V | 1 |
| Ginès, P | 1 |
| Bokemeyer, M | 1 |
| Ding, XQ | 1 |
| Goldbecker, A | 1 |
| Raab, P | 1 |
| Heeren, M | 1 |
| Arvanitis, D | 1 |
| Tillmann, HL | 1 |
| Lanfermann, H | 1 |
| Weissenborn, K | 1 |
| Garcia-Martinez, R | 1 |
| Rovira, A | 1 |
| Alonso, J | 1 |
| Jacas, C | 1 |
| Simón-Talero, M | 1 |
| Vargas, V | 1 |
| Bajaj, JS | 1 |
| Ahluwalia, V | 1 |
| Wade, JB | 1 |
| Sanyal, AJ | 1 |
| White, MB | 1 |
| Noble, NA | 1 |
| Monteith, P | 1 |
| Fuchs, M | 1 |
| Sterling, RK | 1 |
| Luketic, V | 1 |
| Bouneva, I | 1 |
| Stravitz, RT | 1 |
| Puri, P | 1 |
| Kraft, KA | 1 |
| Gilles, H | 1 |
| Heuman, DM | 1 |
| FODOR, O | 2 |
| BORDA, M | 1 |
| MANASIA, M | 1 |
| SANTAY, I | 1 |
| Mechtcheriakov, S | 1 |
| Schocke, M | 1 |
| Kugener, A | 1 |
| Graziadei, IW | 1 |
| Mattedi, M | 1 |
| Hinterhuber, H | 1 |
| Vogel, W | 1 |
| Marksteiner, J | 1 |
| Clementi, V | 1 |
| Tonon, C | 1 |
| Lodi, R | 1 |
| Malucelli, E | 1 |
| Barbiroli, B | 1 |
| Iotti, S | 1 |
| Saksena, S | 1 |
| Rai, V | 1 |
| Saraswat, VA | 2 |
| Rathore, RS | 1 |
| Purwar, A | 1 |
| Kumar, M | 1 |
| Thomas, MA | 2 |
| Gupta, RK | 2 |
| Verma, A | 1 |
| Radha Krishna, Y | 1 |
| Nath, K | 1 |
| Grossi, CE | 1 |
| Prytz, B | 1 |
| Rousselot, LM | 1 |
| Kovacevic, Z | 1 |
| McGivan, JD | 1 |
| Giguère, JF | 2 |
| Butterworth, RF | 3 |
| Danielsen, ER | 1 |
| Michaelis, T | 1 |
| Ross, BD | 3 |
| Schmidt, W | 2 |
| Wolf, G | 2 |
| Grüngreiff, K | 2 |
| Linke, K | 1 |
| Albrecht, J | 4 |
| Hilgier, W | 4 |
| Januszewski, S | 1 |
| Kapuściński, A | 1 |
| Quack, G | 1 |
| Michalak, A | 1 |
| Rose, C | 1 |
| Butterworth, J | 1 |
| Geissler, A | 1 |
| Lock, G | 1 |
| Fründ, R | 1 |
| Held, P | 1 |
| Hollerbach, S | 1 |
| Andus, T | 1 |
| Schölmerich, J | 1 |
| Feuerbach, S | 1 |
| Holstege, A | 1 |
| Van Den Heuvel, AG | 1 |
| Van der Grond, J | 1 |
| Van Rooij, LG | 1 |
| Van Wassenaer-van Hall, HN | 1 |
| Hoogenraad, TU | 1 |
| Mali, WP | 1 |
| Laubenberger, J | 1 |
| Bayer, S | 1 |
| Thiel, T | 1 |
| Hennig, J | 1 |
| Langer, M | 1 |
| Zielińska, M | 2 |
| Borkowska, HD | 1 |
| Gadamski, R | 1 |
| Walski, M | 1 |
| Oja, SS | 1 |
| Saransaari, P | 1 |
| Lee, JH | 1 |
| Seo, DW | 1 |
| Lee, YS | 1 |
| Kim, ST | 1 |
| Mun, CW | 1 |
| Lim, TH | 1 |
| Min, YI | 1 |
| Suh, DJ | 1 |
| Arikan, K | 1 |
| Coskun, T | 1 |
| Guvener, B | 1 |
| Oran, O | 1 |
| Blüml, S | 1 |
| Moreno, A | 1 |
| Hwang, JH | 1 |
| Law, RO | 1 |
| Hindfelt, B | 1 |
| Kreis, R | 1 |
| Farrow, NA | 1 |
| Ackerman, Z | 1 |
| Coraim, FI | 1 |
| Owen, A | 1 |
| Trubel, W | 1 |
| Kassal, H | 1 |
| Widhalm, K | 1 |
| Haugvicova, R | 1 |
| Meier, M | 1 |
| Reum, T | 1 |
| Hartung, HD | 1 |
| Kienzl, E | 1 |
| Riederer, P | 1 |
| Brücke, T | 1 |
| Kleinberger, G | 1 |
| Jellinger, K | 1 |
| Ishikawa, A | 1 |
| Ishiyama, H | 1 |
| Enomoto, T | 1 |
| Ozaki, A | 1 |
| Fukao, K | 1 |
| Okamura, T | 1 |
| Iwasaki, Y | 1 |
| Yamamoto, H | 1 |
| Lavoie, J | 1 |
| Layrargues, GP | 1 |
| Ziegler, K | 1 |
| Leonhardt, H | 2 |
| Bungert, HJ | 1 |
| Berl, S | 1 |
| Melzer, H | 1 |
| Weber, D | 1 |
| Wotzka, R | 1 |
| Szám, I | 1 |
| Müting, D | 1 |
| Popescu, S | 1 |
| Grigoraş, D | 1 |
| Barbarino, F | 1 |
| Nordmann, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role of Magnetic Resonance Imaging in Detection of Minimal Hepatic Encephalopathy[NCT04131205] | 40 participants (Anticipated) | Observational | 2019-06-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for aspartic acid and Hepatic Encephalopathy
| Article | Year |
|---|---|
Magnetic resonance of the brain in chronic and acute liver failure.
Topics: Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Edema; Choline; Creatine; Glutamic Acid; Gl | 2014 |
Mitochondrial metabolism of glutamine and glutamate and its physiological significance.
Topics: Acidosis; Animals; Aspartate Aminotransferases; Aspartic Acid; Brain; Cells, Cultured; Energy Metabo | 1983 |
[Changes in and modulation of receptor activity in hepatic encephalopathy].
Topics: Ammonia; Animals; Aspartic Acid; Binding, Competitive; Biogenic Amines; Blood-Brain Barrier; Brain; | 1985 |
5 trials available for aspartic acid and Hepatic Encephalopathy
| Article | Year |
|---|---|
L-ornithine L-aspartate in acute treatment of severe hepatic encephalopathy: A double-blind randomized controlled trial.
Topics: Ammonia; Aspartic Acid; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Ornithine; Rifax | 2022 |
Letter to the editor: l-ornithine l-aspartate in acute treatment of severe hepatic encephalopathy: A double-blind randomized controlled trial.
Topics: Ammonia; Aspartic Acid; Dipeptides; Double-Blind Method; Hepatic Encephalopathy; Humans; Ornithine | 2022 |
Assessment of glutamate and glutamine contribution to in vivo N-acetylaspartate quantification in human brain by (1)H-magnetic resonance spectroscopy.
Topics: Algorithms; Aspartic Acid; Biomarkers; Brain; Diagnosis, Computer-Assisted; Female; Glutamic Acid; G | 2005 |
[Amino acids prevent hepatic encephalopathy. Ornithine-aspartate in hyperammonemia--results of a study].
Topics: Ammonia; Aspartic Acid; Clinical Trials as Topic; Double-Blind Method; Hepatic Encephalopathy; Human | 1989 |
[On the therapy of liver diseases with ornithine aspartate].
Topics: Acute Disease; Alanine Transaminase; Ammonia; Aspartic Acid; Bilirubin; Cholangitis; Chronic Disease | 1969 |
48 other studies available for aspartic acid and Hepatic Encephalopathy
| Article | Year |
|---|---|
Letter to the editor: Episodic-precipitant-induced hepatic encephalopathy treatment: Look at new and old precipitants!
Topics: Aspartic Acid; Double-Blind Method; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Ornithine | 2022 |
Letter to the editor: Evidence on the use of l-ornithine l-aspartate in overt HE-But does it really improve prognosis?
Topics: Aspartic Acid; Dipeptides; Double-Blind Method; Hepatic Encephalopathy; Humans; Ornithine; Prognosis | 2022 |
Oral magnesium sulphate administration in rats with minimal hepatic encephalopathy: NMR-based metabolic characterization of the brain
Topics: Administration, Oral; Alanine; Animals; Aspartic Acid; Brain; Glutamates; Hepatic Encephalopathy; Ma | 2022 |
Ferrous sulfate reverses cerebral metabolic abnormality induced by minimal hepatic encephalopathy.
Topics: Animals; Arginine; Aspartic Acid; Brain; Glutamic Acid; Glycine; Hepatic Encephalopathy; Iron; Lacti | 2023 |
Neurochemistry of hyponatremic encephalopathy evaluated by MR spectroscopy.
Topics: Aspartic Acid; Child; Creatine; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Humans; Hyponatrem | 2020 |
Solving doubts about L-ornithine L-aspartate for overt hepatic encephalopathy: Whom and how to treat.
Topics: Aspartic Acid; Dipeptides; Hepatic Encephalopathy; Humans; Ornithine | 2018 |
Terminating and episode of overt hepatic encephalopathy: L-ornithine-L-aspartate may have some role.
Topics: Aspartic Acid; Dipeptides; Hepatic Encephalopathy; Humans; Ornithine | 2018 |
Reply.
Topics: Aspartic Acid; Hepatic Encephalopathy; Humans; Ornithine | 2018 |
Risk Factors for Postoperative Prolonged Mechanical Ventilation After Pediatric Liver Transplantation.
Topics: Aspartic Acid; Child; Female; Hepatic Encephalopathy; Humans; Length of Stay; Liver Transplantation; | 2021 |
Viability assessment of magnetic resonance spectroscopy for the detection of minimal hepatic encephalopathy severity.
Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Cognition; Creatine; Female; Glutamic Acid; Glutamine; G | 2015 |
Hyponatremia is a risk factor of hepatic encephalopathy in patients with cirrhosis: a prospective study with time-dependent analysis.
Topics: Adult; Aged; Aspartic Acid; Bilirubin; Brain Chemistry; Creatine; Creatinine; Female; Follow-Up Stud | 2009 |
Evidence for neuroinflammation and neuroprotection in HCV infection-associated encephalopathy.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Mapping; Case-Control Studies; Choline; Cognition Disorders | 2011 |
Hepatic encephalopathy is associated with posttransplant cognitive function and brain volume.
Topics: Adult; Aspartic Acid; Atrophy; Brain; Chi-Square Distribution; Cognition; Cognition Disorders; Femal | 2011 |
Asymmetric dimethylarginine is strongly associated with cognitive dysfunction and brain MR spectroscopic abnormalities in cirrhosis.
Topics: Adult; Arginine; Aspartic Acid; Biomarkers; Brain; Cognition Disorders; Cross-Sectional Studies; Fem | 2013 |
[Research on the ammonium-binding action of aspartic acid in hepatic diseases].
Topics: Ammonia; Ammonium Compounds; Aspartic Acid; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Liver D | 1960 |
Chemical shift magnetic resonance spectroscopy of cingulate grey matter in patients with minimal hepatic encephalopathy.
Topics: Aspartic Acid; Cerebral Cortex; Choline; Creatinine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli | 2005 |
Cerebral diffusion tensor imaging and in vivo proton magnetic resonance spectroscopy in patients with fulminant hepatic failure.
Topics: Adolescent; Adult; Anisotropy; Aspartic Acid; Biomarkers; Case-Control Studies; Cerebrovascular Circ | 2008 |
In vivo 1H magnetic resonance spectroscopy-derived metabolite variations between acute-on-chronic liver failure and acute liver failure.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Case-Control Studies; Choline; Chronic Disease; Creat | 2008 |
Amino acids mixtures in prevention of acute ammonia intoxication in dogs.
Topics: Ammonia; Animals; Aspartic Acid; Blood Urea Nitrogen; Dogs; Hepatic Encephalopathy; Ornithine; Porta | 1967 |
Amino acid changes in regions of the CNS in relation to function in experimental portal-systemic encephalopathy.
Topics: Acetates; Amino Acids; Animals; Aspartic Acid; Central Nervous System; Glutamates; Glutamic Acid; Gl | 1984 |
Three methods of calibration in quantitative proton MR spectroscopy.
Topics: Adult; Aspartic Acid; Body Water; Brain; Brain Chemistry; Brain Injuries; Calibration; Choline; Crea | 1995 |
Adenosine influences the high-affinity uptake of transmitter glutamate and aspartate under conditions of hepatic encephalopathy.
Topics: Adenosine; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Hepatic Encephalopathy; Humans; In Vit | 1993 |
Increase of the brain uptake index for L-ornithine in rats with hepatic encephalopathy.
Topics: Acetates; Animals; Aspartic Acid; Blood-Brain Barrier; Brain; Endothelium; Hepatic Encephalopathy; M | 1994 |
Neuroactive amino acids and glutamate (NMDA) receptors in frontal cortex of rats with experimental acute liver failure.
Topics: Animals; Aspartic Acid; Brain Chemistry; Excitatory Amino Acids; Extracellular Space; gamma-Aminobut | 1996 |
Cerebral abnormalities in patients with cirrhosis detected by proton magnetic resonance spectroscopy and magnetic resonance imaging.
Topics: Adult; Aged; Aspartic Acid; Brain; Choline; Female; Glutamic Acid; Hepatic Encephalopathy; Humans; I | 1997 |
Differentiation between portal-systemic encephalopathy and neurodegenerative disorders in patients with Wilson disease: H-1 MR spectroscopy.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Diseases; Choline; Creatinine; Diagnosis, Differential; Fem | 1997 |
[Clinical uses of proton magnetic resonance spectroscopy of the brain].
Topics: AIDS Dementia Complex; Alzheimer Disease; Animals; Aspartic Acid; Brain; Brain Diseases; Brain Disea | 1998 |
Changes in the extracellular profiles of neuroactive amino acids in the rat striatum at the asymptomatic stage of hepatic failure.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Biological Transport; Corpus Striatum; Excitatory Amin | 1999 |
Proton magnetic resonance spectroscopy (1H-MRS) findings for the brain in patients with liver cirrhosis reflect the hepatic functional reserve.
Topics: Adult; Aged; Aspartic Acid; Basal Ganglia; Brain; Choline; Creatinine; Energy Metabolism; Female; Gl | 1999 |
Effects of ammonia on pentylenetetrazole-induced seizure threshold.
Topics: Ammonia; Animals; Aspartic Acid; Brain; Dose-Response Relationship, Drug; Drug Interactions; gamma-A | 1999 |
1-(13)C glucose magnetic resonance spectroscopy of pediatric and adult brain disorders.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Diseases; Canavan Disease; Carbon Isotopes; Chi | 2001 |
Taurine, glutamine, glutamate, and aspartate content and efflux, and cell volume of cerebrocortical minislices of rats with hepatic encephalopathy: influence of ammonia.
Topics: Ammonia; Animals; Aspartic Acid; Cell Size; Cerebral Cortex; Glutamic Acid; Glutamine; Hepatic Encep | 2000 |
On mechanisms in hyperammonemic coma--with particular reference to hepatic encephalopathy.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Ammonia; Aspartic Acid; Brain; Dose-Response Relation | 1975 |
Metabolic disorders of the brain in chronic hepatic encephalopathy detected with H-1 MR spectroscopy.
Topics: Aspartic Acid; Brain; Choline; Female; Glucose; Glutamates; Glutamic Acid; Glutamine; Hepatic Enceph | 1992 |
Regulatory effect of neurotransmitter by hemofiltration in cardiogenic shock patients after open heart surgery.
Topics: Adolescent; Adult; Aged; Ammonia; Aspartic Acid; Brain Edema; Coronary Artery Bypass; Female; Glasgo | 1991 |
Decreased potassium-stimulated release of [3H]D-aspartate from hippocampal slices distinguishes encephalopathy related to acute liver failure from that induced by simple hyperammonemia.
Topics: Acetates; Animals; Aspartic Acid; Female; Hepatic Encephalopathy; Hippocampus; In Vitro Techniques; | 1991 |
Hepatic encephalopathy influences high-affinity uptake of transmitter glutamate and aspartate into the hippocampal formation.
Topics: Adult; Aged; Aged, 80 and over; Ammonia; Animals; Aspartic Acid; Female; Glutamates; Glutamic Acid; | 1990 |
Hepatic coma and amino acids in the nerve endings of the central nervous system.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Cerebral Cortex; Glutamates; Glutamic Acid; Glycine; Hep | 1985 |
Amino acid changes in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy.
Topics: Aged; Amino Acids; Aspartic Acid; Brain Chemistry; Chromatography, High Pressure Liquid; Female; gam | 1987 |
[Current views on the therapy of hepatic coma].
Topics: Acute Kidney Injury; Adolescent; Amino Acids; Ammonia; Anti-Bacterial Agents; Arginine; Aspartic Aci | 1970 |
Editorial: Towards an artificial liver.
Topics: Acetaminophen; Aspartic Acid; Brain Chemistry; Charcoal; Glutamates; Hepatic Encephalopathy; Hepatit | 1974 |
[Pathogenesis and therapy of exogenous hepatic coma].
Topics: Amino Acids; Aspartic Acid; Brain; Dipeptides; Electroencephalography; Hepatic Encephalopathy; Human | 1973 |
[Therapy of severe hyperammonemia].
Topics: Adult; Aged; Ammonia; Anti-Bacterial Agents; Aspartic Acid; Diet Therapy; Enzyme Induction; Female; | 1972 |
Cerebral amino acid metabolism in hepatic coma.
Topics: Amino Acids; Aminobutyrates; Ammonia; Aspartic Acid; Brain; Cerebral Cortex; Electroencephalography; | 1971 |
[Prevention and therapy of hepatic coma].
Topics: Aged; Amides; Ammonia; Aspartic Acid; Chlorothiazide; Clopamide; Depression, Chemical; Diuretics; Fe | 1970 |
[Treatment of hepatic cirrhosis and hepatic coma with drugs having the capacity of lowering the blood ammonia levels].
Topics: Ammonia; Arginine; Aspartic Acid; Bacteria; Female; Glutamates; Hepatic Encephalopathy; Humans; Live | 1967 |
[Treatment with aspartic acid in hepatic coma caused by hyperammonemia].
Topics: Ammonia; Aspartic Acid; Hepatic Encephalopathy; Humans; Liver Cirrhosis | 1968 |
[Therapy of hyperammoniemia].
Topics: Adenosine Triphosphate; Ammonia; Anti-Bacterial Agents; Arginine; Aspartic Acid; Citrulline; Dietary | 1969 |