aspartic acid has been researched along with Hemochromatosis in 21 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Hemochromatosis: A disorder of iron metabolism characterized by a triad of HEMOSIDEROSIS; LIVER CIRRHOSIS; and DIABETES MELLITUS. It is caused by massive iron deposits in parenchymal cells that may develop after a prolonged increase of iron absorption. (Jablonski's Dictionary of Syndromes & Eponymic Diseases, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hereditary hemochromatosis is associated with homozygosity for C282Y mutation in the HFE gene, elevated serum transferrin saturation and excess iron deposits throughout the body." | 3.72 | Population screening for hemochromatosis: a study in 5370 Spanish blood donors. ( Ascaso, C; Bruguera, M; Ingelmo, M; Oliva, R; Sánchez, M; Sanz, C; Villa, M, 2003) |
| "Hereditary hemochromatosis is the most frequent hereditary metabolic disorder, with lethal outcome without treatment." | 2.42 | [Iron storage disease]. ( Dávid, K; Horváth, G, 2004) |
| "Hereditary HFE Hemochromatosis is an inherited disorder of iron metabolism that results from mutations in the HFE gene." | 1.37 | Prevalence of H63D, S65C, and C282Y hereditary hemochromatosis gene variants in Madeira Island (Portugal). ( Brehm, A; Spínola, C; Spínola, H, 2011) |
| "The metabolic syndrome was present in 23 (27%), hepatic steatosis in 43 (50%), steatohepatitis in 18 (21%) and significant fibrosis in 38 (44%)." | 1.33 | The effect of the metabolic syndrome, hepatic steatosis and steatohepatitis on liver fibrosis in hereditary hemochromatosis. ( Abraham, SC; Adams, LA; Angulo, P; Brandhagen, D; Torgerson, H, 2006) |
| "Hereditary haemochromatosis (HH) is one of the most common inherited diseases among Caucasians." | 1.31 | Haemochromatosis: automated detection of the two point mutations in the HFE gene: Cys282Tyr and His63Asp. ( Klingler, KR; Wielckens, K; Zech, D, 2000) |
| "Haemochromatosis is a common genetic disorder, inherited as an autosomal recessive trait that results in a progressive accumulation of iron in most tissues of the body." | 1.31 | Association studies between haemochromatosis gene mutations and the risk of cardiovascular diseases. ( Amarenco, P; Arveiler, D; Cambien, F; Elbaz, A; Evans, A; Gariepy, J; Grandchamp, B; Hetet, G; Kee, F; Morrison, C; Nicaud, V; Simon, A, 2001) |
| "Hereditary haemochromatosis is an autosomal recessive disease in which there is defective regulation of iron absorption, causing gradual accumulation of excessive amounts of iron in certain organs." | 1.30 | A PCR-SSP method for detecting the His63Asp mutation in the HFE gene associated with hereditary haemochromatosis. ( Smillie, D, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 13 (61.90) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spínola, C | 1 |
| Brehm, A | 1 |
| Spínola, H | 1 |
| Sánchez, M | 1 |
| Villa, M | 1 |
| Ingelmo, M | 1 |
| Sanz, C | 1 |
| Bruguera, M | 1 |
| Ascaso, C | 1 |
| Oliva, R | 1 |
| LEDERER, J | 1 |
| CLOSE, J | 1 |
| Milman, N | 1 |
| Pedersen, P | 1 |
| Ovesen, L | 1 |
| Melsen, GV | 1 |
| Fenger, K | 1 |
| Anderson, GJ | 2 |
| Ramm, GA | 2 |
| Subramaniam, VN | 1 |
| Powell, LW | 2 |
| Horváth, G | 1 |
| Dávid, K | 1 |
| Adams, LA | 1 |
| Angulo, P | 1 |
| Abraham, SC | 1 |
| Torgerson, H | 1 |
| Brandhagen, D | 1 |
| Barton, JC | 1 |
| Shih, WW | 1 |
| Sawada-Hirai, R | 1 |
| Acton, RT | 1 |
| Harmon, L | 1 |
| Rivers, C | 1 |
| Rothenberg, BE | 1 |
| Gottschalk, R | 1 |
| Seidl, C | 1 |
| Löffler, T | 1 |
| Seifried, E | 1 |
| Hoelzer, D | 1 |
| Kaltwasser, JP | 1 |
| Dubois-Laforgue, D | 1 |
| Caillat-Zucman, S | 1 |
| Djilali-Saiah, I | 1 |
| Larger, E | 1 |
| Mercadier, A | 1 |
| Boitard, C | 1 |
| Bach, JF | 1 |
| Timsit, J | 1 |
| Baiget, M | 1 |
| Barceló, MJ | 1 |
| Gimferrer, E | 1 |
| Smillie, D | 1 |
| Cullen, LM | 1 |
| Jazwinska, EC | 1 |
| Umek, RM | 1 |
| Lin, SS | 1 |
| Chen Yp, Y | 1 |
| Irvine, B | 1 |
| Paulluconi, G | 1 |
| Chan, V | 1 |
| Chong, Y | 1 |
| Cheung, L | 1 |
| Vielmetter, J | 1 |
| Farkas, DH | 1 |
| Klingler, KR | 1 |
| Zech, D | 1 |
| Wielckens, K | 1 |
| Hetet, G | 1 |
| Elbaz, A | 1 |
| Gariepy, J | 1 |
| Nicaud, V | 1 |
| Arveiler, D | 1 |
| Morrison, C | 1 |
| Kee, F | 1 |
| Evans, A | 1 |
| Simon, A | 1 |
| Amarenco, P | 1 |
| Cambien, F | 1 |
| Grandchamp, B | 1 |
| Pereira, AC | 1 |
| Cuoco, MA | 1 |
| Mota, GF | 1 |
| da Silva, FF | 1 |
| Freitas, HF | 1 |
| Bocchi, EA | 1 |
| Soler, JM | 1 |
| Mansur, AJ | 1 |
| Krieger, JE | 1 |
| Shiono, Y | 1 |
| Ikeda, R | 1 |
| Hayashi, H | 1 |
| Wakusawa, S | 1 |
| Sanae, F | 1 |
| Takikawa, T | 1 |
| Imaizumi, Y | 1 |
| Yano, M | 1 |
| Yoshioka, K | 1 |
| Kawanaka, M | 1 |
| Yamada, G | 1 |
| Pärlist, P | 1 |
| Mikelsaar, AV | 1 |
| Tasa, G | 1 |
| Beckman, L | 1 |
| Manoharan, A | 1 |
| Waalen, J | 1 |
| Felitti, V | 1 |
| Gelbart, T | 1 |
| Ho, NJ | 1 |
| Beutler, E | 1 |
2 reviews available for aspartic acid and Hemochromatosis
| Article | Year |
|---|---|
[Iron storage disease].
Topics: Aspartic Acid; Carcinoma, Hepatocellular; Chromosomes, Human, Pair 6; Cysteine; Diabetes Mellitus; D | 2004 |
Genetics of hemochromatosis.
Topics: Amino Acid Substitution; Aspartic Acid; Cloning, Molecular; Cysteine; Genes, MHC Class I; Genes, Rec | 1999 |
19 other studies available for aspartic acid and Hemochromatosis
| Article | Year |
|---|---|
Prevalence of H63D, S65C, and C282Y hereditary hemochromatosis gene variants in Madeira Island (Portugal).
Topics: Adolescent; Adult; Amino Acid Substitution; Aspartic Acid; Cysteine; Gene Frequency; Genotype; Hemoc | 2011 |
Population screening for hemochromatosis: a study in 5370 Spanish blood donors.
Topics: Adult; Aspartic Acid; Blood Donors; Cysteine; Female; Ferritins; Gene Frequency; Genetic Testing; Ge | 2003 |
[FERROUS ASPARTATE IN THERAPY].
Topics: Absorption; Anemia; Anemia, Hypochromic; Aspartic Acid; Biomedical Research; Blood Chemical Analysis | 1964 |
Frequency of the C282Y and H63D mutations of the hemochromatosis gene (HFE) in 2501 ethnic Danes.
Topics: Aspartic Acid; Confidence Intervals; Cysteine; Denmark; Female; Gene Frequency; Genotype; Hemochroma | 2004 |
HFE gene and hemochromatosis.
Topics: Aspartic Acid; Cysteine; Gene Frequency; Hemochromatosis; Hemochromatosis Protein; Heterozygote; His | 2004 |
The effect of the metabolic syndrome, hepatic steatosis and steatohepatitis on liver fibrosis in hereditary hemochromatosis.
Topics: Adult; Aged; Aspartic Acid; Cysteine; Fatty Liver; Female; Genetic Predisposition to Disease; Glucos | 2006 |
Genetic and clinical description of hemochromatosis probands and heterozygotes: evidence that multiple genes linked to the major histocompatibility complex are responsible for hemochromatosis.
Topics: Adult; Alleles; Aspartic Acid; Chromosomes, Human, Pair 6; Cysteine; Female; Gene Frequency; Genes, | 1997 |
HFE codon 63/282 (H63D/C282Y) dimorphism in German patients with genetic hemochromatosis.
Topics: Aspartic Acid; Codon; Cysteine; Female; Genotype; Germany; Hemochromatosis; Hemochromatosis Protein; | 1998 |
Mutations in HFE, the hemochromatosis candidate gene, in patients with NIDDM.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Diabetes Mellitus, Type 2; Hemochromatosis; Hemoch | 1998 |
Frequency of the HFE C282Y and H63D mutations in distinct ethnic groups living in Spain.
Topics: Alleles; Aspartic Acid; Cysteine; Ethnicity; Genotype; Hemochromatosis; Hemochromatosis Protein; His | 1998 |
A PCR-SSP method for detecting the His63Asp mutation in the HFE gene associated with hereditary haemochromatosis.
Topics: Amino Acid Substitution; Aspartic Acid; Chromosomes, Human, Pair 6; DNA Primers; Electrophoresis, Ag | 1998 |
Bioelectronic detection of point mutations using discrimination of the H63D polymorphism of the Hfe gene as a model.
Topics: Amino Acid Substitution; Aspartic Acid; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidin | 2000 |
Haemochromatosis: automated detection of the two point mutations in the HFE gene: Cys282Tyr and His63Asp.
Topics: Aspartic Acid; Cysteine; DNA Mutational Analysis; Hemochromatosis; Hemochromatosis Protein; Heterozy | 2000 |
Association studies between haemochromatosis gene mutations and the risk of cardiovascular diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arteriosclerosis; Aspartic Acid; Brain Infarction; Cardi | 2001 |
Hemochromatosis gene variants in patients with cardiomyopathy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Cardiomyopathies; Cysteine; Disease Progression; Female; Gen | 2001 |
C282Y and H63D mutations in the HFE gene have no effect on iron overload disorders in Japan.
Topics: Adult; Asian People; Aspartic Acid; Cysteine; Female; Hemochromatosis; Hemochromatosis Protein; Hepa | 2001 |
The frequency of C282Y and H63D mutations in Hemochromatosis gene in native Estonians.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Aspartic Acid; Cysteine; DNA Mutational Analysi | 2001 |
Population screening for HFE-associated haemochromatosis.
Topics: Aspartic Acid; Australia; Genetic Testing; Hemochromatosis; Hemochromatosis Protein; Histidine; Hist | 2001 |
Prevalence of hemochromatosis-related symptoms among individuals with mutations in the HFE gene.
Topics: Adult; Aged; Aspartic Acid; Case-Control Studies; Cysteine; Double-Blind Method; Female; Ferritins; | 2002 |