aspartic acid has been researched along with Graves Disease in 3 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Development of Graves' disease (GD) is related to HLA-DRB1*0301 (DR3),and more specifically to arginine at position 74 of the DRB1 molecule." | 5.36 | The role of glutamic or aspartic acid in position four of the epitope binding motif and thyrotropin receptor-extracellular domain epitope selection in Graves' disease. ( Ardito, M; De Groot, AS; De Groot, LJ; Inaba, H; Martin, W, 2010) |
| "Graves' disease is an autoimmune disease of the thyroid gland." | 5.35 | Reduced parietooccipital white matter glutamine measured by proton magnetic resonance spectroscopy in treated graves' disease patients. ( Danielsen, ER; Dock, J; Elberling, TV; Feldt-Rasmussen, U; Hørding, M; Perrild, H; Rasmussen, AK; Thomsen, C; Waldemar, G, 2008) |
| "Development of Graves' disease (GD) is related to HLA-DRB1*0301 (DR3),and more specifically to arginine at position 74 of the DRB1 molecule." | 1.36 | The role of glutamic or aspartic acid in position four of the epitope binding motif and thyrotropin receptor-extracellular domain epitope selection in Graves' disease. ( Ardito, M; De Groot, AS; De Groot, LJ; Inaba, H; Martin, W, 2010) |
| "Graves' disease is an autoimmune disease of the thyroid gland." | 1.35 | Reduced parietooccipital white matter glutamine measured by proton magnetic resonance spectroscopy in treated graves' disease patients. ( Danielsen, ER; Dock, J; Elberling, TV; Feldt-Rasmussen, U; Hørding, M; Perrild, H; Rasmussen, AK; Thomsen, C; Waldemar, G, 2008) |
| "Patients with Graves' disease (n = 160) and healthy controls (blood donors; n = 140) were screened using single-stranded conformational polymorphism (SSCP) in combination with restriction enzyme digestion for the two previously known mutations in this part of the receptor, viz." | 1.30 | Analysis of mutations in exon 1 of the human thyrotropin receptor gene: high frequency of the D36H and P52T polymorphic variants. ( Bengtsson, M; Heldin, NE; Kinch, A; Schuppert, F; Simanainen, J; Westermark, B; Westermark, K; Winsa, B, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Inaba, H | 1 |
| Martin, W | 1 |
| Ardito, M | 1 |
| De Groot, AS | 1 |
| De Groot, LJ | 1 |
| Danielsen, ER | 1 |
| Elberling, TV | 1 |
| Rasmussen, AK | 1 |
| Dock, J | 1 |
| Hørding, M | 1 |
| Perrild, H | 1 |
| Waldemar, G | 1 |
| Feldt-Rasmussen, U | 1 |
| Thomsen, C | 1 |
| Simanainen, J | 1 |
| Kinch, A | 1 |
| Westermark, K | 1 |
| Winsa, B | 1 |
| Bengtsson, M | 1 |
| Schuppert, F | 1 |
| Westermark, B | 1 |
| Heldin, NE | 1 |
3 other studies available for aspartic acid and Graves Disease
| Article | Year |
|---|---|
The role of glutamic or aspartic acid in position four of the epitope binding motif and thyrotropin receptor-extracellular domain epitope selection in Graves' disease.
Topics: Amino Acid Substitution; Animals; Antigen Presentation; Aspartic Acid; Epitopes; Extracellular Space | 2010 |
Reduced parietooccipital white matter glutamine measured by proton magnetic resonance spectroscopy in treated graves' disease patients.
Topics: Adult; Aspartic Acid; Choline; Dipeptides; Female; Glutamic Acid; Glutamine; Graves Disease; Humans; | 2008 |
Analysis of mutations in exon 1 of the human thyrotropin receptor gene: high frequency of the D36H and P52T polymorphic variants.
Topics: Alleles; Amino Acid Substitution; Aspartic Acid; Exons; Female; Gene Frequency; Genetic Testing; Gra | 1999 |