aspartic acid has been researched along with Glioma in 151 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
Excerpt | Relevance | Reference |
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"We performed serial (1)H-MRSI examinations to assess intratumoral metabolite intensities in 16 patients receiving high-dose oral tamoxifen monotherapy for recurrent malignant glioma (WHO grade III or IV) as part of a phase II clinical trial." | 9.13 | Prospective serial proton MR spectroscopic assessment of response to tamoxifen for recurrent malignant glioma. ( Arnold, DL; Assina, R; Caramanos, Z; Langleben, A; Leblanc, R; Preul, MC; Sankar, T; Villemure, JG, 2008) |
"This study was designed to evaluate proton magnetic resonance spectroscopy ((1)H-MRS) for monitoring the WHO grade II glioma (low-grade glioma (LGG)) treated with temozolomide (TMZ)." | 7.77 | Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy. ( Abud, L; Capelle, L; Chiras, J; Costalat, R; De Marco, G; Guillevin, R; Habas, C; Hoang-Xuan, K; Menuel, C; Taillibert, S; Vallée, JN, 2011) |
"The purpose of this study was to determine the predictive value of [18F]fluoroethyl-L-tyrosine (FET)-positron emission tomography (PET) and magnetic resonance (MR) spectroscopy for tumor diagnosis in patients with suspected gliomas." | 7.73 | Multimodal metabolic imaging of cerebral gliomas: positron emission tomography with [18F]fluoroethyl-L-tyrosine and magnetic resonance spectroscopy. ( Coenen, H; Floeth, FW; Hamacher, K; Langen, KJ; Messing-Jünger, M; Müller, HW; Pauleit, D; Reifenberger, G; Sabel, M; Steiger, HJ; Stummer, W; Weber, F; Wittsack, HJ; Woebker, G; Zilles, K, 2005) |
"Non-saturable penetration and the V and Km constants of saturable influx of leucine, lysine and glycine were always greater in cultured neuroblastoma (C1300) than in glioma (C6) cells." | 7.67 | Transport of leucine, lysine, glycine and aspartate in neuroblastoma C1300 and glioma C6 cells. ( Hannuniemi, R; Oja, OS; Oja, SS; Pajari-Backas, M, 1987) |
" This preclinical study sought to test the efficacy of the food additive Triacetin (glyceryl triacetate, GTA) as a novel therapy to increase acetate bioavailability in glioma cells." | 5.40 | Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma. ( Davies, MT; Driscoll, HE; Jaworski, DM; Lawler, SE; Long, PM; Penar, PL; Pendlebury, WW; Spees, JL; Teasdale, BA; Tsen, AR; Viapiano, MS, 2014) |
"We performed serial (1)H-MRSI examinations to assess intratumoral metabolite intensities in 16 patients receiving high-dose oral tamoxifen monotherapy for recurrent malignant glioma (WHO grade III or IV) as part of a phase II clinical trial." | 5.13 | Prospective serial proton MR spectroscopic assessment of response to tamoxifen for recurrent malignant glioma. ( Arnold, DL; Assina, R; Caramanos, Z; Langleben, A; Leblanc, R; Preul, MC; Sankar, T; Villemure, JG, 2008) |
" There are a number of metabolites that can be identified by standard brain proton MRS but only a few of them has a clinical significance in diagnosis of gliomas including N-acetylaspartate, choline, creatine, myo-inositol, lactate, and lipids." | 4.89 | Potential of MR spectroscopy for assessment of glioma grading. ( Bulik, M; Jancalek, R; Mechl, M; Skoch, A; Vanicek, J, 2013) |
" These methods were evaluated for segmentation of volumetric MRSI studies of gliomas using maps of the choline to N-acetylaspartate ratio, and a qualitative comparison of lesion volumes carried out." | 3.91 | Lesion segmentation for MR spectroscopic imaging using the convolution difference method. ( Maudsley, AA, 2019) |
"There is significant elevation of the choline (Cho) /creatine (Cr) ratio, Cho peak and depression of the N-acetylaspartate (NAA) peak in gliomas." | 3.78 | Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas. ( Shang, HB; Zhang, WF; Zhao, WG, 2012) |
"This study was designed to evaluate proton magnetic resonance spectroscopy ((1)H-MRS) for monitoring the WHO grade II glioma (low-grade glioma (LGG)) treated with temozolomide (TMZ)." | 3.77 | Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy. ( Abud, L; Capelle, L; Chiras, J; Costalat, R; De Marco, G; Guillevin, R; Habas, C; Hoang-Xuan, K; Menuel, C; Taillibert, S; Vallée, JN, 2011) |
" The aim of this work is to evaluate whether regional cerebral blood volume (rCBV), as well as choline (Cho), N-acetyl-aspartate (NAA) and myo-inositol (mIns) concentrations differ between tumefactive lesions and World Health Organization (WHO) grade II-III gliomas." | 3.77 | Metabolism and regional cerebral blood volume in autoimmune inflammatory demyelinating lesions mimicking malignant gliomas. ( Blasel, S; Hattingen, E; Jansen, V; Mueller, K; Pfeilschifter, W; Zanella, F, 2011) |
"Diffusion tensor imaging (DTI) and MR spectroscopy are noninvasive, quantitative tools for the preoperative assessment of gliomas with which the quantitative parameter fractional anisotropy (FA) and the concentration of neurometabolites N-acetylaspartate (NAA), choline (Cho), creatine (Cr) of the brain can be determined." | 3.73 | Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients--a combined diffusion tensor imaging and 1H-MR spectroscopy study. ( Ding, XQ; Fiehler, J; Goebell, E; Hagel, C; Heese, O; Kucinski, T; Nietz, S; Paustenbach, S; Westphal, M; Zeumer, H, 2006) |
"In vivo magnetic resonance spectroscopy (MRS) studies of glial brain tumours reported that higher grade of astrocytoma is associated with increased level of choline-containing compounds (Cho) and decreased levels of N-acetylaspartate (NAA) and creatine and phosphocreatine (Cr)." | 3.73 | In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy. ( Belan, V; Béres, A; De Riggo, J; Dobrota, D; Galanda, M; Likavcanová, K; Liptaj, T; Mlynárik, V; Prónayová, N, 2005) |
"The purpose of this study was to determine the predictive value of [18F]fluoroethyl-L-tyrosine (FET)-positron emission tomography (PET) and magnetic resonance (MR) spectroscopy for tumor diagnosis in patients with suspected gliomas." | 3.73 | Multimodal metabolic imaging of cerebral gliomas: positron emission tomography with [18F]fluoroethyl-L-tyrosine and magnetic resonance spectroscopy. ( Coenen, H; Floeth, FW; Hamacher, K; Langen, KJ; Messing-Jünger, M; Müller, HW; Pauleit, D; Reifenberger, G; Sabel, M; Steiger, HJ; Stummer, W; Weber, F; Wittsack, HJ; Woebker, G; Zilles, K, 2005) |
"To evaluate an intracranial polymer implant containing bromodeoxyuridine (BrdUrd) and N-(phosphonacetyl)-L-aspartic acid (PALA) in combination with external beam radiotherapy (EBRT) in the treatment of a rat glioma." | 3.72 | Treatment of intracranial rat glioma model with implant of radiosensitizer and biomodulator drug combined with external beam radiotherapy. ( Lehnert, S; Li, Y; Owusu, A, 2004) |
" The concentration of taurine (Tau) in medulloblastomas was 29." | 3.72 | In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard. ( Harada, K; Houkin, K; Tong, Z; Yamaki, T, 2004) |
" The concentration of taurine (Tau) in medulloblastomas was 29." | 3.72 | In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard. ( Harada, K; Houkin, K; Tong, Z; Yamaki, T, 2004) |
"Data obtained preoperatively from three-dimensional (3D)/proton magnetic resonance (MR) spectroscopy were compared with the results of histopathological assays of tissue biopsies obtained during surgery to verify the sensitivity and specificity of a choline-containing compound-N-acetylaspartate index (CNI) used to distinguish tumor from nontumorous tissue within T2-hyperintense and contrast-enhancing lesions of patients with untreated gliomas." | 3.71 | Histopathological validation of a three-dimensional magnetic resonance spectroscopy index as a predictor of tumor presence. ( Berger, MS; Dillon, WP; Graves, EE; Lu, Y; McDermott, MW; McKnight, TR; Nelson, SJ; Pirzkall, A; Vigneron, DB; von dem Bussche, MH, 2002) |
" MRS of normal brain parenchyma displays 4 main metabolites: N-acetyl aspartate (neuronal marker), creatine (cellular density marker), choline (membrane activity marker) and myoinositol (glial marker); pathological processes lead to variations of the level of these metabolites and/or the appearance of abnormal metabolites (lactate), following different patterns according to pathological process involved: glioma, meningioma, metastasis, bacterial or toxoplasmic abscess, radionecrosis." | 3.71 | [Contribution of magnetic resonance spectrometry to the diagnosis of intracranial tumors]. ( Confort-Gouny, S; Cozzone, PJ; Dufour, H; Galanaud, D; Le Fur, Y; Nicoli, F; Peragut, JC; Ranjeva, JP; Roche, P; Viout, P, 2002) |
" Non-neoplastic lesions such as cerebral infarctions and brain abscesses are marked by decreases in choline (Cho), creatine (Cr) and N-acetyl-aspartate (NAA), while tumours generally have elevated Cho and decreased levels of Cr and NAA." | 3.71 | Clinical application of proton magnetic resonance spectroscopy in the diagnosis of intracranial mass lesions. ( Herminghaus, S; Krings, T; Lanfermann, H; Marquardt, G; Möller-Hartmann, W; Pilatus, U; Zanella, FE, 2002) |
"We found in cultured glioma (C6BU-1) cells that excitatory amino acids (EAAs) such as glutamate, N-methyl-D-aspartate (NMDA), aspartate, and metabotropic glutamate receptor agonist trans-(+/-)-1-amino-1,3-cyclopentanedicarboxylate caused an increase in the inositol 1,4,5-trisphosphate formation and the intracellular Ca2+ concentration ([Ca2+]i) in the absence of extracellular Mg2+ and Ca2+." | 3.69 | Metabotropic glutamate receptor in C6BU-1 glioma cell has NMDA receptor-ion channel complex-like properties and interacts with serotonin2 receptor-stimulated signal transduction. ( Mikuni, M; Saitoh, K; Shinno, H; Takahashi, K; Tomita, U; Yamawaki, S, 1994) |
" Spectroscopy is a reliable technique for grading of gliomas when N-acetyl-aspartate/choline and choline/creatine ratios and presence of lipids are used in combination." | 3.69 | Characterization of intracranial mass lesions with in vivo proton MR spectroscopy. ( Chhabra, DK; Gupta, RK; Jain, VK; Pandey, R; Poptani, H; Roy, R, 1995) |
" The NAA (N-acetylaspartate)/Cho (choline) ratio of Grade 2 astrocytoma was higher than that of Grade 4." | 3.69 | Non-invasive characterization of brain tumor by in-vivo proton magnetic resonance spectroscopy. ( Bandou, K; Harada, M; Kannuki, S; Miyoshi, H; Nishitani, H; Tanouchi, M, 1995) |
"(a) Hamartomas showed higher N-acetyl aspartate/creatine, creatine/choline, and N-acetyl aspartate/choline ratios than gliomas." | 3.69 | Proton MR spectroscopy in patients with neurofibromatosis type 1: evaluation of hamartomas and clinical correlation. ( Castillo, M; Green, C; Greenwood, R; Kwock, L; Schiro, S; Smith, K; Wilson, D, 1995) |
" We used proton nuclear magnetic resonance spectroscopy to detect the presence of simple metabolites (such as lactic acid, creatine/phosphocreatine, N-acetyl aspartate, and the "choline" pool) in extracts of a human glioma grown subcutaneously in athymic ("nu/nu") mice." | 3.69 | Effects of therapy on the 1H NMR spectrum of a human glioma line. ( Cazzaniga, S; Charles, HC; Schold, SC; Sostman, HD, 1994) |
" Oligodendrogliomas had higher choline levels than astrocytomas." | 3.68 | [1H magnetic resonance spectroscopy in intracranial tumors and cerebral ischemia]. ( Felber, SR, 1993) |
"Endothelin (ET)-related peptides robustly stimulated [3H]-inositol phosphate (IP) formation in cultured cerebellar granule cells, astrocytes, and C6 glioma cells." | 3.68 | Endothelin-induced activation of phosphoinositide turnover, calcium mobilization, and transmitter release in cultured neurons and neurally related cell types. ( Chuang, DM; Lee, CY; Lin, WW, 1991) |
"Non-saturable penetration and the V and Km constants of saturable influx of leucine, lysine and glycine were always greater in cultured neuroblastoma (C1300) than in glioma (C6) cells." | 3.67 | Transport of leucine, lysine, glycine and aspartate in neuroblastoma C1300 and glioma C6 cells. ( Hannuniemi, R; Oja, OS; Oja, SS; Pajari-Backas, M, 1987) |
"Seizures are common in patients with gliomas; however, the mechanisms of epileptogenesis in gliomas have not been fully understood." | 1.62 | Association of preoperative seizures with tumor metabolites quantified by magnetic resonance spectroscopy in gliomas. ( Abe, M; Hirose, Y; Inamasu, J; Kumon, M; Kuwahara, K; Murayama, K; Nakae, S; Ohba, S; Sasaki, H; Yamada, S, 2021) |
"Chordoid gliomas are extremely rare entities, which are generally considered occurring exclusively in the third ventricle." | 1.56 | Chordoid glioma: an entity occurring not exclusively in the third ventricle. ( Du, J; Fang, J; Li, G; Wang, S; Xu, Y; Yang, B; Yang, C, 2020) |
"Glioma is the most common type of the primary CNS tumor." | 1.43 | Noninvasive evaluation of radiation-enhanced glioma cells invasiveness by ultra-high-field (1)H-MRS in vitro. ( Cui, Y; Li, FY; Li, HX; Shi, WQ; Wang, JZ; Xu, YJ; Zeng, QS, 2016) |
" This preclinical study sought to test the efficacy of the food additive Triacetin (glyceryl triacetate, GTA) as a novel therapy to increase acetate bioavailability in glioma cells." | 1.40 | Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma. ( Davies, MT; Driscoll, HE; Jaworski, DM; Lawler, SE; Long, PM; Penar, PL; Pendlebury, WW; Spees, JL; Teasdale, BA; Tsen, AR; Viapiano, MS, 2014) |
"High grade gliomas are known to release excitotoxic concentrations of glutamate, a process thought to contribute to their malignant phenotype through enhanced autocrine stimulation of their proliferation and destruction of the surrounding nervous tissue." | 1.35 | Enhanced expression of the high affinity glutamate transporter GLT-1 in C6 glioma cells delays tumour progression in rat. ( Abarca-Quinones, J; Gallez, B; Hermans, E; Jordan, BF; Maloteaux, JM; Vanhoutte, N, 2009) |
"Using discriminant analysis, this study found that MR spectroscopy in combination with ADC ratio, rather than ADC value, can improve the ability to differentiate recurrent glioma and radiation injury." | 1.34 | Distinction between recurrent glioma and radiation injury using magnetic resonance spectroscopy in combination with diffusion-weighted imaging. ( Feng, DC; Li, CF; Liu, H; Zeng, QS; Zhen, JH, 2007) |
"Ten patients with untreated gliomas were examined on a 1." | 1.32 | Improved delineation of brain tumors: an automated method for segmentation based on pathologic changes of 1H-MRSI metabolites in gliomas. ( Buslei, R; Fahlbusch, R; Ganslandt, O; Gruber, S; Moser, E; Nimsky, C; Stadlbauer, A, 2004) |
"Most of the brain tumors were characterized by strongly reduced total N-acetylaspartyl compounds and marked increases of myo-inositol and choline-containing compounds, consistent with a lack of neuroaxonal tissue and a proliferation of glial cells." | 1.31 | Quantitative proton magnetic resonance spectroscopy of focal brain lesions. ( Dechent, P; Frahm, J; Hanefeld, F; Herms, J; Markakis, E; Maxton, C; Wilken, B, 2000) |
"The diagnosis of brain tumors after high-dose radiation therapy is frequently limited by the lack of metabolic discrimination available with conventional imaging methods." | 1.31 | Serial proton MR spectroscopic imaging of recurrent malignant gliomas after gamma knife radiosurgery. ( Chang, S; Dillon, WP; Graves, EE; Larson, D; McDermott, M; Nelson, SJ; Prados, MD; Verhey, L; Vigneron, DB, 2001) |
"High-grade brain tumors are known to have a high rate of glucose (Glc) consumption." | 1.31 | High glycolytic activity in rat glioma demonstrated in vivo by correlation peak 1H magnetic resonance imaging. ( Décorps, M; Rémy, C; von Kienlin , M; Ziegler, A, 2001) |
"First, it allows to distinguish brain tumors from abscesses." | 1.31 | [Brain tumors: interest of magnetic resonance spectroscopy for the diagnosis and the prognosis]. ( Berry, I; Ibarrola, D; Malet-Martino, M; Sabatier, J, 2001) |
"Seventeen brain tumors were measured by 1H-CSI (chemical shift imaging) in a 1." | 1.30 | Evaluation of metabolic heterogeneity in brain tumors using 1H-chemical shift imaging method. ( Furuya, S; Ide, M; Kizu, O; Maeda, T; Morishita, H; Naruse, S; Ueda, S, 1997) |
"Choline signals were increased in tumour margins of high grade gliomas and more diffusely in low grade gliomas." | 1.29 | Localized proton spectroscopy of inoperable brain gliomas. Response to radiation therapy. ( Go, KG; Heesters, MA; Kamman, RL; Mooyaart, EL, 1993) |
"Seventy patients with intracranial neoplasms were studied before receiving surgery, radiotherapy or chemotherapy." | 1.29 | Proton magnetic resonance spectroscopy and intracranial tumours: clinical perspectives. ( Calabrese, G; Falini, A; Lipari, S; Losa, M; Origgi, D; Scotti, G; Triulzi, F, 1996) |
"Higher grades of brain tumors in this study were associated with higher Cho/reference and lower NAA/reference values." | 1.29 | Noninvasive evaluation of malignancy of brain tumors with proton MR spectroscopy. ( Arai, N; Fujiwara, S; Hara, K; Kayama, T; Kumabe, T; Ono, Y; Sato, K; Shimizu, H; Tominaga, T; Yoshimoto, T, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (3.31) | 18.7374 |
1990's | 29 (19.21) | 18.2507 |
2000's | 58 (38.41) | 29.6817 |
2010's | 51 (33.77) | 24.3611 |
2020's | 8 (5.30) | 2.80 |
Authors | Studies |
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Rudnay, M | 1 |
Waczulikova, I | 1 |
Bullova, A | 1 |
Rjaskova, G | 1 |
Chorvath, M | 1 |
Jezberova, M | 1 |
Lehotska, V | 1 |
Tran, D | 3 |
Nguyen, DH | 3 |
Nguyen, HK | 3 |
Nguyen-Thanh, VA | 3 |
Dong-Van, H | 3 |
Nguyen, MD | 3 |
De Stefano, FA | 1 |
Morell, AA | 1 |
Smith, G | 1 |
Warner, T | 1 |
Soldozy, S | 1 |
Elarjani, T | 1 |
Eichberg, DG | 1 |
Luther, E | 1 |
Komotar, RJ | 1 |
Yang, B | 1 |
Yang, C | 1 |
Du, J | 1 |
Fang, J | 1 |
Li, G | 1 |
Wang, S | 1 |
Xu, Y | 1 |
Goryawala, M | 1 |
Saraf-Lavi, E | 1 |
Nagornaya, N | 1 |
Heros, D | 1 |
Komotar, R | 1 |
Maudsley, AA | 2 |
Wang, AP | 1 |
Suryavanshi, T | 1 |
Marcucci, M | 1 |
Fong, C | 1 |
Whitton, AC | 1 |
Reddy, KKV | 1 |
Nakae, S | 1 |
Kumon, M | 1 |
Murayama, K | 1 |
Ohba, S | 1 |
Sasaki, H | 1 |
Inamasu, J | 1 |
Kuwahara, K | 1 |
Yamada, S | 1 |
Abe, M | 1 |
Hirose, Y | 1 |
Alirezaei, Z | 1 |
Amouheidari, A | 1 |
Hassanpour, M | 1 |
Davanian, F | 1 |
Iraji, S | 1 |
Shokrani, P | 1 |
Nazem-Zadeh, MR | 1 |
Ditter, P | 1 |
Hattingen, E | 3 |
Liu, Z | 1 |
Zhang, J | 4 |
Lai, M | 1 |
Vassallo, I | 1 |
Lanz, B | 1 |
Poitry-Yamate, C | 1 |
Hamou, MF | 1 |
Cudalbu, C | 1 |
Gruetter, R | 1 |
Hegi, ME | 1 |
Gao, W | 1 |
Wang, X | 1 |
Li, F | 2 |
Shi, W | 1 |
Li, H | 1 |
Zeng, Q | 2 |
Pedrosa de Barros, N | 1 |
Meier, R | 1 |
Pletscher, M | 1 |
Stettler, S | 1 |
Knecht, U | 1 |
Herrmann, E | 1 |
Schucht, P | 1 |
Reyes, M | 1 |
Gralla, J | 1 |
Wiest, R | 1 |
Slotboom, J | 1 |
Corbetta, C | 1 |
Di Ianni, N | 1 |
Bruzzone, MG | 2 |
Patanè, M | 1 |
Pollo, B | 1 |
Cantini, G | 1 |
Cominelli, M | 1 |
Zucca, I | 1 |
Pisati, F | 1 |
Poliani, PL | 1 |
Finocchiaro, G | 2 |
Pellegatta, S | 1 |
Choi, C | 3 |
Ganji, S | 1 |
Hulsey, K | 1 |
Madan, A | 2 |
Kovacs, Z | 2 |
Dimitrov, I | 1 |
Zhang, S | 1 |
Pichumani, K | 1 |
Mendelsohn, D | 1 |
Mickey, B | 1 |
Malloy, C | 1 |
Bachoo, R | 1 |
Deberardinis, R | 1 |
Maher, E | 1 |
Balos, DR | 1 |
Gavrilović, S | 1 |
Lavrnić, S | 1 |
Vasić, B | 1 |
Macvanski, M | 1 |
Damjanović, D | 1 |
Opinćal, TS | 1 |
Tsen, AR | 1 |
Long, PM | 1 |
Driscoll, HE | 1 |
Davies, MT | 1 |
Teasdale, BA | 1 |
Penar, PL | 1 |
Pendlebury, WW | 1 |
Spees, JL | 1 |
Lawler, SE | 1 |
Viapiano, MS | 1 |
Jaworski, DM | 1 |
Roder, C | 1 |
Skardelly, M | 1 |
Ramina, KF | 1 |
Beschorner, R | 1 |
Honneger, J | 1 |
Nägele, T | 1 |
Tatagiba, MS | 1 |
Ernemann, U | 1 |
Bisdas, S | 1 |
Bertolino, N | 1 |
Marchionni, C | 1 |
Ghielmetti, F | 1 |
Burns, B | 1 |
Anghileri, E | 1 |
Minati, L | 1 |
Pereira, MS | 1 |
Zenki, K | 1 |
Cavalheiro, MM | 1 |
Thomé, CC | 1 |
Filippi-Chiela, EC | 1 |
Lenz, G | 1 |
de Souza, DO | 1 |
de Oliveira, DL | 1 |
Raschke, F | 1 |
Jones, TL | 1 |
Barrick, TR | 1 |
Howe, FA | 1 |
Ganji, SK | 2 |
An, Z | 1 |
Choe, KS | 1 |
Pinho, MC | 1 |
Bachoo, RM | 2 |
Maher, EM | 1 |
Stadler, KL | 1 |
Ober, CP | 1 |
Feeney, DA | 1 |
Jessen, CR | 1 |
Yamamoto, T | 1 |
Isobe, T | 1 |
Akutsu, H | 1 |
Masumoto, T | 1 |
Ando, H | 1 |
Sato, E | 1 |
Takada, K | 1 |
Anno, I | 1 |
Matsumura, A | 1 |
Ranjith, G | 1 |
Parvathy, R | 1 |
Vikas, V | 1 |
Chandrasekharan, K | 1 |
Nair, S | 1 |
Ghasemi, K | 1 |
Khanmohammadi, M | 1 |
Saligheh Rad, H | 1 |
Tong, T | 1 |
Yang, Z | 1 |
Chen, JW | 1 |
Zhu, J | 1 |
Yao, Z | 1 |
Lotumolo, A | 2 |
Caivano, R | 2 |
Rabasco, P | 2 |
Iannelli, G | 1 |
Villonio, A | 2 |
D' Antuono, F | 1 |
Gioioso, M | 1 |
Zandolino, A | 2 |
Macarini, L | 2 |
Guglielmi, G | 1 |
Cammarota, A | 2 |
Wang, Q | 1 |
Zhang, H | 1 |
Wu, C | 1 |
Zhu, W | 1 |
Chen, X | 1 |
Xu, B | 1 |
Zhuang, DX | 1 |
Yao, CJ | 1 |
Lin, CP | 1 |
Wang, TL | 1 |
Qin, ZY | 1 |
Wu, JS | 1 |
Jarmusch, AK | 1 |
Pirro, V | 1 |
Baird, Z | 1 |
Hattab, EM | 1 |
Cohen-Gadol, AA | 1 |
Cooks, RG | 1 |
Carrera, I | 1 |
Richter, H | 1 |
Beckmann, K | 1 |
Meier, D | 1 |
Dennler, M | 1 |
Kircher, PR | 1 |
Wang, C | 1 |
Chen, H | 2 |
Zhang, M | 1 |
Wei, X | 1 |
Ying, W | 1 |
Xu, YJ | 1 |
Cui, Y | 1 |
Li, HX | 1 |
Shi, WQ | 1 |
Li, FY | 1 |
Wang, JZ | 1 |
Zeng, QS | 3 |
Roldan-Valadez, E | 1 |
Rios, C | 1 |
Motola-Kuba, D | 1 |
Matus-Santos, J | 1 |
Villa, AR | 1 |
Moreno-Jimenez, S | 1 |
Sankar, T | 2 |
Caramanos, Z | 2 |
Assina, R | 1 |
Villemure, JG | 1 |
Leblanc, R | 1 |
Langleben, A | 1 |
Arnold, DL | 3 |
Preul, MC | 2 |
Li, Y | 2 |
Srinivasan, R | 1 |
Ratiney, H | 1 |
Lu, Y | 3 |
Chang, SM | 2 |
Nelson, SJ | 6 |
Douis, H | 1 |
Jafri, M | 1 |
Sherlala, K | 1 |
Murphy, A | 1 |
Vines, A | 1 |
McBean, GJ | 1 |
Vanhoutte, N | 1 |
Abarca-Quinones, J | 1 |
Jordan, BF | 1 |
Gallez, B | 1 |
Maloteaux, JM | 1 |
Hermans, E | 1 |
Blamek, S | 1 |
Larysz, D | 1 |
Ficek, K | 1 |
Sokół, M | 2 |
Miszczyk, L | 1 |
Tarnawski, R | 1 |
Matsusue, E | 1 |
Fink, JR | 1 |
Rockhill, JK | 1 |
Ogawa, T | 1 |
Maravilla, KR | 1 |
Goenka, AH | 1 |
Kumar, A | 1 |
Sharma, R | 1 |
Kuznetsov, YE | 1 |
Ryan, RW | 1 |
Antel, SB | 1 |
Server, A | 3 |
Josefsen, R | 2 |
Kulle, B | 2 |
Maehlen, J | 1 |
Schellhorn, T | 1 |
Gadmar, Ø | 1 |
Kumar, T | 2 |
Haakonsen, M | 1 |
Langberg, CW | 1 |
Nakstad, PH | 2 |
Sijens, PE | 1 |
Stadlbauer, A | 5 |
Buchfelder, M | 2 |
Doelken, MT | 1 |
Hammen, T | 3 |
Ganslandt, O | 5 |
Gadmar, ØB | 1 |
Liu, X | 1 |
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Blasel, S | 1 |
Pfeilschifter, W | 1 |
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Haberkorn, U | 1 |
Kauczor, HU | 1 |
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Liu, H | 3 |
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Minchev, G | 1 |
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Taillibert, S | 1 |
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Costalat, R | 1 |
Abud, L | 1 |
Habas, C | 1 |
De Marco, G | 1 |
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Chiras, J | 1 |
Vallée, JN | 1 |
Amin, A | 1 |
Moustafa, H | 1 |
Ahmed, E | 1 |
El-Toukhy, M | 1 |
DeBerardinis, RJ | 1 |
Hatanpaa, KJ | 1 |
Rakheja, D | 1 |
Yang, XL | 1 |
Mashimo, T | 1 |
Raisanen, JM | 1 |
Marin-Valencia, I | 1 |
Pascual, JM | 1 |
Madden, CJ | 1 |
Mickey, BE | 1 |
Malloy, CR | 1 |
Maher, EA | 1 |
Nicolasjilwan, M | 1 |
Lopes, MB | 1 |
Larner, J | 1 |
Wintermark, M | 1 |
Schiff, D | 1 |
Steffen-Smith, EA | 1 |
Venzon, DJ | 1 |
Bent, RS | 1 |
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Van Roost, D | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Prospective Study About the Validity of MRS-guided Resection on Prognosis High-grade Gliomas[NCT02795364] | 50 participants (Anticipated) | Interventional | 2016-06-30 | Not yet recruiting | |||
Multi-paramEtric Imaging to Assess Treatment REsponse After Stereotactic Radiosurgery of Brain Metastases[NCT04626206] | 12 participants (Anticipated) | Observational | 2020-12-31 | Not yet recruiting | |||
Treatment Development of Triheptanoin for Glucose Transporter Type I Deficiency[NCT02021526] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2015-12-31 | Withdrawn (stopped due to NIH funding resulted in new clinical trial) | ||
Metabolic Characterization of Space Occupying Lesions of the Brain Using in Vivo MR- (Spectroscopic) Imaging at 3 Tesla and 7 Tesla[NCT04233788] | 55 participants (Anticipated) | Observational | 2021-09-01 | Recruiting | |||
Combination of 11C-MET PET and MRS in the Diagnosis of Glioma.[NCT03009318] | 100 participants (Actual) | Interventional | 2012-01-31 | Completed | |||
Study of Clinical Biomarkers in Human Health and Disease (Healthiomics)[NCT05106725] | 3,500 participants (Anticipated) | Observational | 2021-10-11 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
6 reviews available for aspartic acid and Glioma
Article | Year |
---|---|
Unique magnetic resonance spectroscopy profile of intracranial meningiomas compared to gliomas: a systematic review.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Magnetic Resonance Spectr | 2023 |
The diagnostic performance of magnetic resonance spectroscopy in differentiating high-from low-grade gliomas: A systematic review and meta-analysis.
Topics: Area Under Curve; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Databases, Factual; Glioma; Hum | 2016 |
Potential of MR spectroscopy for assessment of glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Inositol; Lactates; Lipid Metabol | 2013 |
3 Tesla magnetic resonance spectroscopy: cerebral gliomas vs. metastatic brain tumors. Our experience and review of the literature.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Diagnosis, Differ | 2013 |
Proton magnetic resonance spectroscopic evaluation of brain tumor metabolism.
Topics: Alanine; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Glutamic Acid; Glutamine; Humans | 2004 |
Brain stem involvement in children with neurofibromatosis type 1: role of magnetic resonance imaging and spectroscopy in the distinction from diffuse pontine glioma.
Topics: Adolescent; Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Choline; Creatine; | 1997 |
4 trials available for aspartic acid and Glioma
Article | Year |
---|---|
Prospective serial proton MR spectroscopic assessment of response to tamoxifen for recurrent malignant glioma.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Dis | 2008 |
Distinction between high-grade gliomas and solitary metastases using peritumoral 3-T magnetic resonance spectroscopy, diffusion, and perfusion imagings.
Topics: Adult; Aged; Aspartic Acid; Blood Volume; Brain; Brain Neoplasms; Cerebrovascular Circulation; Choli | 2004 |
Correlation of magnetic resonance spectroscopic and growth characteristics within Grades II and III gliomas.
Topics: Antibodies, Antinuclear; Antibodies, Monoclonal; Apoptosis; Aspartic Acid; Brain Neoplasms; Cell Pro | 2007 |
Multivoxel 3D proton MR spectroscopy in the distinction of recurrent glioma from radiation injury.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Fema | 2007 |
141 other studies available for aspartic acid and Glioma
Article | Year |
---|---|
Magnetic resonance spectroscopy - its added value in brain glioma multiparametric assessment.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Magnetic Resonance Spectro | 2021 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Chordoid glioma: an entity occurring not exclusively in the third ventricle.
Topics: Adult; Aged; Aspartic Acid; Cerebellum; Cerebral Ventricle Neoplasms; Choline; Diffusion Magnetic Re | 2020 |
The Association between Whole-Brain MR Spectroscopy and IDH Mutation Status in Gliomas.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Isocitrate | 2020 |
Radiation Necrosis Following Stereotactic Radiosurgery for Trigeminal Neuralgia.
Topics: Aged, 80 and over; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Creatine; Diagnostic Err | 2020 |
Association of preoperative seizures with tumor metabolites quantified by magnetic resonance spectroscopy in gliomas.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytes; Brain Neoplasms; Female; Glioma; Glutamic | 2021 |
Early Detection of Radiation-Induced Injury and Prediction of Cognitive Deficit by MRS Metabolites in Radiotherapy of Low-Grade Glioma.
Topics: Adolescent; Adult; Aspartic Acid; Brain Neoplasms; Cognitive Dysfunction; Creatine; Early Diagnosis; | 2021 |
[Magnetic resonance spectroscopy of brain tumors].
Topics: Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Magnetic Resonance Imaging | 2017 |
Age, choline-to-N-acetyl aspartate, and lipids-lactate-to-creatine ratios assemble a significant Cox's proportional-hazards regression model for survival prediction in patients with high-grade gliomas.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Lactic Acid; Lipids; Magnetic Res | 2017 |
In vivo characterization of brain metabolism by
Topics: Adaptor Proteins, Signal Transducing; Animals; Aspartic Acid; Brain; Brain Neoplasms; Cell Line, Tum | 2018 |
Cho/Cr ratio at MR spectroscopy as a biomarker for cellular proliferation activity and prognosis in glioma: correlation with the expression of minichromosome maintenance protein 2.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biomarkers; Brain; Brain Neoplasms; Cell Proliferation; Chil | 2019 |
On the relation between MR spectroscopy features and the distance to MRI-visible solid tumor in GBM patients.
Topics: Algorithms; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Glioma; Healthy Volunteers; Hu | 2018 |
Lesion segmentation for MR spectroscopic imaging using the convolution difference method.
Topics: Algorithms; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Computer Simulation; Glio | 2019 |
Altered function of the glutamate-aspartate transporter GLAST, a potential therapeutic target in glioblastoma.
Topics: Amino Acid Transport System X-AG; Animals; Apoptosis; Aspartic Acid; Astrocytes; Benzopyrans; Cell L | 2019 |
A comparative study of short- and long-TE ¹H MRS at 3 T for in vivo detection of 2-hydroxyglutarate in brain tumors.
Topics: Adult; Aspartic Acid; Brain Neoplasms; gamma-Aminobutyric Acid; Glioma; Glutamic Acid; Glutamine; Gl | 2013 |
Proton magnetic resonance spectroscopy and apparent diffusion coefficient in evaluation of solid brain lesions.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Child; Choline; Creatine; Diffusion | 2013 |
Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma.
Topics: Amidohydrolases; Animals; Antifungal Agents; Aspartic Acid; Astrocytes; Brain; Brain Neoplasms; Cell | 2014 |
Spectroscopy imaging in intraoperative MR suite: tissue characterization and optimization of tumor resection.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Image | 2014 |
Accuracy of 2-hydroxyglutarate quantification by short-echo proton-MRS at 3 T: a phantom study.
Topics: Aspartic Acid; Brain; Glioma; Glutamic Acid; Glutarates; Humans; Isocitrate Dehydrogenase; Mutation; | 2014 |
Cellular senescence induced by prolonged subculture adversely affects glutamate uptake in C6 lineage.
Topics: Animals; Aspartic Acid; Cellular Senescence; Glioma; Glutamic Acid; Rats, Wistar; Tritium; Tumor Cel | 2014 |
Delineation of gliomas using radial metabolite indexing.
Topics: Algorithms; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Diagnosis, Computer-Assisted | 2014 |
Proton T2 measurement and quantification of lactate in brain tumors by MRS at 3 Tesla in vivo.
Topics: Adult; Aged; Artifacts; Aspartic Acid; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Female; | 2015 |
Multivoxel proton magnetic resonance spectroscopy of inflammatory and neoplastic lesions of the canine brain at 3.0 T.
Topics: Analysis of Variance; Animals; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, | 2014 |
Influence of echo time in quantitative proton MR spectroscopy using LCModel.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Image Processing, Computer | 2015 |
Machine learning methods for the classification of gliomas: Initial results using features extracted from MR spectroscopy.
Topics: Algorithms; Artificial Intelligence; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Cre | 2015 |
Accurate grading of brain gliomas by soft independent modeling of class analogy based on non-negative matrix factorization of proton magnetic resonance spectra.
Topics: Algorithms; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Glycine; Humans; Neoplasm Gra | 2016 |
Dynamic 1H-MRS assessment of brain tumors: a novel approach for differential diagnosis of glioma.
Topics: Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Case-Control Studies; Choline; Diagnosis, Differe | 2015 |
Comparison between magnetic resonance spectroscopy and diffusion weighted imaging in the evaluation of gliomas response after treatment.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Neoplasms; Choline; Diffusion Magnetic Resonanc | 2015 |
Metabolic approach for tumor delineation in glioma surgery: 3D MR spectroscopy image-guided resection.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Diffusion Tensor Imaging; Feasibility S | 2016 |
Lipid and metabolite profiles of human brain tumors by desorption electrospray ionization-MS.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Cell Differentiation; Glioma; Gray Matter; Humans; Lipid Meta | 2016 |
Evaluation of intracranial neoplasia and noninfectious meningoencephalitis in dogs by use of short echo time, single voxel proton magnetic resonance spectroscopy at 3.0 Tesla.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Case-Control Studies; Creatine; Dog Diseases; Dogs; Female; | 2016 |
Malate-aspartate shuttle inhibitor aminooxyacetic acid leads to decreased intracellular ATP levels and altered cell cycle of C6 glioma cells by inhibiting glycolysis.
Topics: Adenosine Triphosphate; Aminooxyacetic Acid; Animals; Antineoplastic Agents; Apoptosis; Aspartic Aci | 2016 |
Noninvasive evaluation of radiation-enhanced glioma cells invasiveness by ultra-high-field (1)H-MRS in vitro.
Topics: Aspartic Acid; Brain Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Choline; C | 2016 |
Choline-to-N-acetyl aspartate and lipids-lactate-to-creatine ratios together with age assemble a significant Cox's proportional-hazards regression model for prediction of survival in high-grade gliomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Cre | 2016 |
Comparison of T(1) and T(2) metabolite relaxation times in glioma and normal brain at 3T.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Gliom | 2008 |
Bilateral thalamic glioma.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Magnetic Resonance Imagin | 2008 |
Stimulation of EAAC1 in C6 glioma cells by store-operated calcium influx.
Topics: Animals; Aspartic Acid; Biological Transport; Calcium; Cell Line, Tumor; Excitatory Amino Acid Trans | 2009 |
Enhanced expression of the high affinity glutamate transporter GLT-1 in C6 glioma cells delays tumour progression in rat.
Topics: Animals; Aspartic Acid; Cell Line, Tumor; Corpus Striatum; Disease Models, Animal; Disease Progressi | 2009 |
MR spectroscopic evaluation of brain tissue damage after treatment for pediatric brain tumors.
Topics: Adolescent; Aspartic Acid; Brain; Brain Neoplasms; Child; Choline; Creatine; Ependymoma; Female; Gli | 2010 |
Distinction between glioma progression and post-radiation change by combined physiologic MR imaging.
Topics: Adult; Aspartic Acid; Blood Volume; Brain; Brain Neoplasms; Cerebrovascular Circulation; Choline; Cr | 2010 |
MR spectroscopy for differentiation of recurrent glioma from radiation-induced changes.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Child; Child, Preschool; Choline; Contrast | 2009 |
The metabolic epicenter of supratentorial gliomas: a 1H-MRSI study.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Aspartic Acid; Chi-Square Distribution; Cholin | 2009 |
Proton magnetic resonance spectroscopy in the distinction of high-grade cerebral gliomas from single metastatic brain tumors.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Contrast Media; | 2010 |
Response to article "Proton magnetic resonance spectroscopy in the distinction of high-grade cerebral gliomas from single metastatic brain tumors".
Topics: Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Creatinine; Edema; Glioma; Humans; Image Enhanc | 2010 |
Response to a letter by Paul E. Sijens.
Topics: Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Creatinine; Edema; Glioma; Humans; Image Enhanc | 2010 |
Magnetic resonance spectroscopic imaging for visualization of the infiltration zone of glioma.
Topics: Adult; Aspartic Acid; Astrocytoma; Biopsy; Brain Neoplasms; Choline; Data Interpretation, Statistica | 2011 |
Measurements of diagnostic examination performance using quantitative apparent diffusion coefficient and proton MR spectroscopic imaging in the preoperative evaluation of tumor grade in cerebral gliomas.
Topics: Area Under Curve; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Diffusion Magnetic Resonance Im | 2011 |
N-Acetyl peak in MR spectra of intracranial metastatic mucinous adenocarcinomas.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Aspartic Acid; Biopsy; Brain; Brain Neoplasms; Diagn | 2010 |
Metabolism and regional cerebral blood volume in autoimmune inflammatory demyelinating lesions mimicking malignant gliomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Blood Volume; Brain Neoplasms; Cerebrovas | 2011 |
Biopsy targeting gliomas: do functional imaging techniques identify similar target areas?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Biopsy; Brain Neoplasms; Choline; Contras | 2010 |
Noninvasive evaluation of cerebral glioma grade by using multivoxel 3D proton MR spectroscopy.
Topics: Adult; Aged; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Creatine; Female; Glioma; H | 2011 |
Value of 1H-magnetic resonance spectroscopy chemical shift imaging for detection of anaplastic foci in diffusely infiltrating gliomas with non-significant contrast-enhancement.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Glioma; H | 2011 |
Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Aspartic Acid; Brain Neoplasms; Choline; Creatine; D | 2011 |
Glioma residual or recurrence versus radiation necrosis: accuracy of pentavalent technetium-99m-dimercaptosuccinic acid [Tc-99m (V) DMSA] brain SPECT compared to proton magnetic resonance spectroscopy (1H-MRS): initial results.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Female; Follow-Up Studie | 2012 |
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.
Topics: Algorithms; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Creatine; Female; Glioma; | 2012 |
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.
Topics: Algorithms; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Creatine; Female; Glioma; | 2012 |
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.
Topics: Algorithms; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Creatine; Female; Glioma; | 2012 |
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.
Topics: Algorithms; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Creatine; Female; Glioma; | 2012 |
Subependymal seeding of low-grade oligodendroglial neoplasms: a case series.
Topics: Adult; Aspartic Acid; Creatine; Disease Progression; Ependyma; Fourth Ventricle; Glioma; Humans; Iso | 2012 |
Single- and multivoxel proton spectroscopy in pediatric patients with diffuse intrinsic pontine glioma.
Topics: Adolescent; Aspartic Acid; Brain Stem Neoplasms; Child; Child, Preschool; Choline; Creatine; Feasibi | 2012 |
Progressive multifocal leukoencephalopathy (PML) mimicking high-grade glioma on delayed F-18 FDG PET imaging.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Fluorodeoxy | 2012 |
The relationship between Cho/NAA and glioma metabolism: implementation for margin delineation of cerebral gliomas.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy, Needle; Brain Neoplasms; Choline; Female; Glioma; Hu | 2012 |
The relationship between Cho/NAA and glioma metabolism: implementation for margin delineation of cerebral gliomas.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy, Needle; Brain Neoplasms; Choline; Female; Glioma; Hu | 2012 |
The relationship between Cho/NAA and glioma metabolism: implementation for margin delineation of cerebral gliomas.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy, Needle; Brain Neoplasms; Choline; Female; Glioma; Hu | 2012 |
The relationship between Cho/NAA and glioma metabolism: implementation for margin delineation of cerebral gliomas.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy, Needle; Brain Neoplasms; Choline; Female; Glioma; Hu | 2012 |
Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas.
Topics: Adolescent; Adult; Aged; Anisotropy; Aspartic Acid; Brain Neoplasms; Cerebral Cortex; Child; Choline | 2012 |
Conservative management of presumed low-grade gliomas in the asymptomatic pediatric population.
Topics: Adolescent; Aspartic Acid; Astrocytoma; Asymptomatic Diseases; Brain Neoplasms; Child; Child, Presch | 2014 |
Proton MR spectroscopy of tumefactive demyelinating lesions.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Creatine; Demyelinating Diseases; Diagnosis, Different | 2002 |
Histopathological validation of a three-dimensional magnetic resonance spectroscopy index as a predictor of tumor presence.
Topics: Aspartic Acid; Biopsy; Brain Neoplasms; Choline; Glioma; Humans; Magnetic Resonance Spectroscopy; Pr | 2002 |
Combination of single-voxel proton MR spectroscopy and apparent diffusion coefficient calculation in the evaluation of common brain tumors.
Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creat | 2003 |
[Contribution of magnetic resonance spectrometry to the diagnosis of intracranial tumors].
Topics: Aspartic Acid; Biomarkers; Brain Abscess; Brain Neoplasms; Choline; Computer Graphics; Creatine; Dia | 2002 |
A chemometric approach for brain tumor classification using magnetic resonance imaging and spectroscopy.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Cerebrospinal Fluid; Choline; Creatine; Disc | 2003 |
Treatment of intracranial rat glioma model with implant of radiosensitizer and biomodulator drug combined with external beam radiotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Brain Neoplasms; Bromodeoxyu | 2004 |
1H-MRSI of radiation effects in normal-appearing white matter: dose-dependence and impact on automated spectral classification.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Dose-Response Relationshi | 2004 |
In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cerebellar Neoplasms; C | 2004 |
In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard.
Topics: Adult; Aged; Aspartic Acid; Body Water; Brain; Brain Neoplasms; Child; Child, Preschool; Choline; Cr | 2004 |
Improved delineation of brain tumors: an automated method for segmentation based on pathologic changes of 1H-MRSI metabolites in gliomas.
Topics: Adult; Algorithms; Aspartic Acid; Astrocytoma; Automation; Biopsy; Brain Chemistry; Brain Mapping; B | 2004 |
Proton magnetic resonance spectroscopy of brain tumors correlated with pathology.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatin | 2005 |
Clinicopathological examination of glioma by proton magnetic resonance spectroscopy background.
Topics: Adult; Aspartic Acid; Brain Neoplasms; Choline; Female; Glioma; Humans; Lactic Acid; Magnetic Resona | 2004 |
Multimodal metabolic imaging of cerebral gliomas: positron emission tomography with [18F]fluoroethyl-L-tyrosine and magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy; Brain; Brain Neoplasms; Child; Child, Preschool; Cho | 2005 |
Spectroscopy and navigation.
Topics: Algorithms; Aspartic Acid; Brain; Brain Neoplasms; Choline; Glioma; Humans; Image Processing, Comput | 2005 |
Proton magnetic resonance spectroscopic imaging integrated into image-guided surgery: correlation to standard magnetic resonance imaging and tumor cell density.
Topics: Algorithms; Aspartic Acid; Biopsy; Brain Neoplasms; Cell Count; Choline; Feasibility Studies; Glioma | 2005 |
Longitudinal multivoxel MR spectroscopy study of pediatric diffuse brainstem gliomas treated with radiotherapy.
Topics: Aspartic Acid; Brain Stem Neoplasms; Child; Child, Preschool; Choline; Creatine; Disease Progression | 2005 |
Proton magnetic resonance spectroscopy of normal human brain and glioma: a quantitative in vivo study.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Glioma; Glycine; Humans; Inositol; Magnetic | 2005 |
Multisection 1H magnetic resonance spectroscopic imaging assessment of glioma response to chemotherapy.
Topics: Adult; Antineoplastic Agents; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Disease-Free Surviv | 2006 |
Assessing global invasion of newly diagnosed glial tumors with whole-brain proton MR spectroscopy.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Chemistry; Female; Glioma; Humans; Magnetic Resonance Spect | 2005 |
Independent component analysis to proton spectroscopic imaging data of human brain tumours.
Topics: Algorithms; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cell Proliferation; Choline; Creatine; Glio | 2005 |
In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Astrocytes; Astrocytoma; Brain; Brain Neoplasms; Choline; Chromium; Creatine; Gliobla | 2005 |
Preoperative grading of gliomas by using metabolite quantification with high-spatial-resolution proton MR spectroscopic imaging.
Topics: Adolescent; Adult; Aspartic Acid; Brain Neoplasms; Case-Control Studies; Choline; Creatine; Female; | 2006 |
Multiparametric 3T MR approach to the assessment of cerebral gliomas: tumor extent and malignancy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Contrast Media; Creatine; Diffusio | 2006 |
3T 1H-MR spectroscopy in grading of cerebral gliomas: comparison of short and intermediate echo time sequences.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Echo-Planar Imaging; Female; Glioma; | 2006 |
Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients--a combined diffusion tensor imaging and 1H-MR spectroscopy study.
Topics: Adult; Aged; Anisotropy; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cell Size; Choline; Cre | 2006 |
Long-term normal-appearing brain tissue monitoring after irradiation using proton magnetic resonance spectroscopy in vivo: statistical analysis of a large group of patients.
Topics: Adult; Aged; Aspartic Acid; Blood-Brain Barrier; Brain; Brain Neoplasms; Choline; Creatine; Female; | 2006 |
Comments and controversies: magnetic resonance spectroscopy and gliomas.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Magnetic Resonance Spectroscopy; | 2006 |
Proton magnetic resonance spectroscopy in childhood brainstem lesions.
Topics: Adolescent; Amino Acids; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Stem; Brain Stem Neop | 2007 |
Distinction between recurrent glioma and radiation injury using magnetic resonance spectroscopy in combination with diffusion-weighted imaging.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Diagnosis, Differential; Diffusion Magn | 2007 |
Proton magnetic resonance spectroscopic imaging in the border zone of gliomas: correlation of metabolic and histological changes at low tumor infiltration--initial results.
Topics: Aspartic Acid; Choline; Creatine; Glioma; Humans; Magnetic Resonance Spectroscopy; Neoplasm Invasive | 2007 |
Multimodal MRI in the characterization of glial neoplasms: the combined role of single-voxel MR spectroscopy, diffusion imaging and echo-planar perfusion imaging.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy; Blood Flow Velocity; Brain; Brain Neoplasms; Choline | 2007 |
Monovoxel 1H magnetic resonance spectroscopy in the progression of gliomas.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Disease Progression; Female; Glioma; | 2007 |
C6 glioma cells differentiated by retinoic acid overexpress the glutamate transporter excitatory amino acid carrier 1 (EAAC1).
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Cell Differentiation; Cell Line, Tumor; Dose-Response | 2008 |
Low-grade glioma: correlation of short echo time 1H-MR spectroscopy with 23Na MR imaging.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Female; Glioma; Humans; Magnetic Resonance Imaging; Ma | 2008 |
In vivo proton MR spectroscopy of human gliomas: definition of metabolic coordinates for multi-dimensional classification.
Topics: Adult; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Cluster Analysis; Creatine; Discriminan | 1995 |
Characterization of intracranial mass lesions with in vivo proton MR spectroscopy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Child; Choline; Crea | 1995 |
Metabotropic glutamate receptor in C6BU-1 glioma cell has NMDA receptor-ion channel complex-like properties and interacts with serotonin2 receptor-stimulated signal transduction.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cell Line; Cycloleucine; Dizocilpine M | 1994 |
Spectral editing with adiabatic pulses.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Carbon Isotopes; Choline; Creatine; Feasibility Studies; Gl | 1995 |
Localised proton spectroscopy and spectroscopic imaging in cerebral gliomas, with comparison to positron emission tomography.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Edema; Carbon Radioisotopes; Creatine; Deoxyglucose; Fl | 1995 |
Non-invasive characterization of brain tumor by in-vivo proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Ependymoma; Glioma; Humans; Magnetic | 1995 |
Proton MR spectroscopy in patients with neurofibromatosis type 1: evaluation of hamartomas and clinical correlation.
Topics: Adolescent; Adult; Aspartic Acid; Astrocytoma; Brain; Brain Diseases; Brain Neoplasms; Cerebellar Di | 1995 |
Metabolic flux determination in C6 glioma cells using carbon-13 distribution upon [1-13C]glucose incubation.
Topics: Alanine; Aspartic Acid; Carbon Isotopes; Citric Acid Cycle; Glioma; Gluconeogenesis; Glucose; Glutam | 1993 |
Attenuation by chlormethiazole of oedema following focal ischaemia in the cerebral cortex of the rat.
Topics: Animals; Aspartic Acid; Body Water; Brain Edema; Cerebral Cortex; Cerebral Infarction; Cerebrovascul | 1994 |
Effects of therapy on the 1H NMR spectrum of a human glioma line.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Lactates; Magnetic Resonance Spe | 1994 |
Proton MR spectroscopy of experimental brain tumors in vivo.
Topics: Animals; Aspartic Acid; Blood Glucose; Brain Edema; Brain Neoplasms; Caudate Nucleus; Cell Line; Cho | 1994 |
Localized proton spectroscopy of inoperable brain gliomas. Response to radiation therapy.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Glioma; Humans; Lactates; Lactic Acid; Magnetic Resonance I | 1993 |
Quantitative proton spectroscopy and histology of a canine brain tumor model.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Dogs; Glioma; Lactates; Lactic Acid; Mag | 1993 |
[1H magnetic resonance spectroscopy in intracranial tumors and cerebral ischemia].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Ischemia; Child; Child, Preschool; | 1993 |
Noninvasive evaluation of malignancy of brain tumors with proton MR spectroscopy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Energy Metabolism; Femal | 1996 |
Rapid stimulation of EAAC1-mediated Na+-dependent L-glutamate transport activity in C6 glioma cells by phorbol ester.
Topics: Adenylyl Cyclases; Amiloride; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding | 1996 |
Proton magnetic resonance spectroscopy and intracranial tumours: clinical perspectives.
Topics: Adenoma; Aspartic Acid; Brain Neoplasms; Choline; Craniopharyngioma; Creatinine; Glioma; Humans; Lym | 1996 |
Evaluation of metabolic heterogeneity in brain tumors using 1H-chemical shift imaging method.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Evaluation Studies as Topic; Glioma; Humans; Imag | 1997 |
Increased choline signal coinciding with malignant degeneration of cerebral gliomas: a serial proton magnetic resonance spectroscopy imaging study.
Topics: Adult; Aged; Aspartic Acid; Biomarkers, Tumor; Biopsy; Brain Neoplasms; Cell Transformation, Neoplas | 1997 |
Proton (1H) MR spectroscopy for routine diagnostic evaluation of brain lesions.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Diseases; Brain Neo | 1997 |
Impairment of excitatory amino acid transport in astroglial cells infected with the human immunodeficiency virus type 1.
Topics: Aspartic Acid; Astrocytes; Biological Transport; Gene Products, nef; Glioma; Glutamic Acid; HIV Enve | 1998 |
[1-(13)C]glucose metabolism in the tumoral and nontumoral cerebral tissue of a glioma-bearing rat.
Topics: Alanine; Amino Acids; Analysis of Variance; Animals; Aspartic Acid; Body Weight; Brain; Brain Neopla | 1999 |
Comparison of relative cerebral blood volume and proton spectroscopy in patients with treated gliomas.
Topics: Adult; Aspartic Acid; Blood Volume; Brain; Brain Neoplasms; Choline; Combined Modality Therapy; Fema | 2000 |
Fas drives cell cycle progression in glioma cells via extracellular signal-regulated kinase activation.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Aspartic Acid; Caspase Inhibitors; Caspases; Cell Cycle; | 2000 |
Quantitative proton magnetic resonance spectroscopy of focal brain lesions.
Topics: Adolescent; Aspartic Acid; Biomarkers, Tumor; Brain; Brain Abscess; Brain Diseases; Brain Neoplasms; | 2000 |
An automated technique for the quantitative assessment of 3D-MRSI data from patients with glioma.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Female; Glioma; Humans; Imaging, Three-Dimens | 2001 |
Altered expression of glutamate transporters under hypoxic conditions in vitro.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Carrier Proteins; Cell Death; Cell Hypoxia | 2001 |
Serial proton MR spectroscopic imaging of recurrent malignant gliomas after gamma knife radiosurgery.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Energy Metabolism; Female; Follow-Up Studies; | 2001 |
Proton magnetic resonance chemical shift imaging (1H CSI)-directed stereotactic biopsy.
Topics: Adult; Aspartic Acid; Biopsy, Needle; Brain; Brain Neoplasms; Creatine; Diagnosis, Differential; Ene | 2001 |
High glycolytic activity in rat glioma demonstrated in vivo by correlation peak 1H magnetic resonance imaging.
Topics: Alanine; Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Ethanolamines; Female; Glioma; | 2001 |
Mapping extracellular pH in rat brain gliomas in vivo by 1H magnetic resonance spectroscopic imaging: comparison with maps of metabolites.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Buffers; Choline; Contrast Media; Creatine; Extracellular S | 2001 |
Correlation between magnetic resonance spectroscopy imaging and image-guided biopsies: semiquantitative and qualitative histopathological analyses of patients with untreated glioma.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Dominance, Cerebr | 2001 |
[Brain tumors: interest of magnetic resonance spectroscopy for the diagnosis and the prognosis].
Topics: Aspartic Acid; Biopsy; Brain; Brain Neoplasms; Choline; Diagnosis, Differential; Energy Metabolism; | 2001 |
High-grade gliomas and solitary metastases: differentiation by using perfusion and proton spectroscopic MR imaging.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Blood Volume; Brain; Brain Chemistry; Bra | 2002 |
Clinical application of proton magnetic resonance spectroscopy in the diagnosis of intracranial mass lesions.
Topics: Aspartic Acid; Brain Abscess; Brain Neoplasms; Cerebral Infarction; Choline; Creatine; Diagnosis, Di | 2002 |
Effects of N-(phosphonacetyl)-L-aspartate on murine tumors and normal tissues in vivo and in vitro and the relationship of sensitivity to rate of proliferation and level of aspartate transcarbamylase.
Topics: Animals; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Cells, Cult | 1978 |
Effect of inhibitors of N-linked oligosaccharide processing on the high-affinity transport of D-aspartate by C6 glioma cells.
Topics: 1-Deoxynojirimycin; Aspartic Acid; Biological Transport; Glioma; Glucosamine; Glucosidases; Glycosyl | 1992 |
Proton magnetic resonance spectroscopic imaging for metabolic characterization of demyelinating plaques.
Topics: Acute Disease; Adult; Aspartic Acid; Biopsy; Brain Chemistry; Brain Neoplasms; Choline; Creatine; De | 1992 |
Endothelin-induced activation of phosphoinositide turnover, calcium mobilization, and transmitter release in cultured neurons and neurally related cell types.
Topics: Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Endothelins; Glioma; Inositol; Neurons | 1991 |
Spatially localized in vivo 1H magnetic resonance spectroscopy of an intracerebral rat glioma.
Topics: Animals; Aspartic Acid; Brain; Brain Neoplasms; Creatine; Female; Glioma; Hydrogen; Lactates; Lactic | 1992 |
Inhibition by trypsin of the high-affinity acidic amino acid transport system in C6 glioma cells.
Topics: Animals; Aspartic Acid; Energy Metabolism; Glioma; Rats; Trypsin; Tumor Cells, Cultured | 1990 |
Detection of metabolic heterogeneity of human intracranial tumors in vivo by 1H NMR spectroscopic imaging.
Topics: Adult; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Creatine; Glioma; Humans; Magnetic Resona | 1990 |
Noninvasive differentiation of tumors with use of localized H-1 MR spectroscopy in vivo: initial experience in patients with cerebral tumors.
Topics: Adult; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplasms; Choline; Creatinine; Cysts; | 1989 |
Non-linear kinetics of glutamyl-tRNA synthesis catalyzed by high molecular weight complexes from rat brain neuronal cells but not from glial cells.
Topics: Acylation; Amino Acyl-tRNA Synthetases; Animals; Aspartic Acid; Brain; Catalysis; Cell Line; Glioma; | 1986 |
Transport of leucine, lysine, glycine and aspartate in neuroblastoma C1300 and glioma C6 cells.
Topics: Animals; Aspartic Acid; Cell Line, Transformed; Glioma; Glycine; Humans; Leucine; Lysine; Neuroblast | 1987 |
N-acetyl-L-aspartic acid content of human neural tumours and bovine peripheral nervous tissues.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Cattle; Cerebral Cortex; Craniopharyngioma; Glioblastoma; G | 1972 |