aspartic acid has been researched along with Gaucher Disease in 5 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Gaucher Disease: An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fabry and Gaucher diseases are rare progressive inherited disorders of glycosphingolipid metabolism that affect multiple organ systems." | 1.37 | Magnetic resonance spectroscopy in patients with Fabry and Gaucher disease. ( Bodamer, O; Bogner, W; Gruber, S; Krssak, M; Stadlbauer, A, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, D | 1 |
| Hwang, H | 1 |
| Choi, S | 1 |
| Kwon, SH | 1 |
| Lee, S | 1 |
| Park, JH | 1 |
| Kim, S | 1 |
| Ko, HS | 1 |
| Razek, AA | 1 |
| Abdalla, A | 1 |
| Gaber, NA | 1 |
| Fathy, A | 1 |
| Megahed, A | 1 |
| Barakat, T | 1 |
| Latif Alsayed, MA | 1 |
| Gruber, S | 1 |
| Bogner, W | 1 |
| Stadlbauer, A | 1 |
| Krssak, M | 1 |
| Bodamer, O | 1 |
| Tedeschi, G | 1 |
| Schiffmann, R | 1 |
| Barton, NW | 1 |
| Shih, HH | 1 |
| Gospe, SM | 1 |
| Brady, RO | 1 |
| Alger, JR | 1 |
| Di Chiro, G | 1 |
| Choy, FY | 1 |
| Humphries, ML | 1 |
| Ben-Yoseph, Y | 1 |
5 other studies available for aspartic acid and Gaucher Disease
| Article | Year |
|---|---|
D409H GBA1 mutation accelerates the progression of pathology in A53T α-synuclein transgenic mouse model.
Topics: alpha-Synuclein; Animals; Aspartic Acid; Brain Stem; Disease Progression; Endoplasmic Reticulum Stre | 2018 |
Proton MR Spectroscopy of the brain in children with neuronopathic Gaucher's disease.
Topics: Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Child, Preschool; Choline; Creatine; Diagnosis, D | 2013 |
Magnetic resonance spectroscopy in patients with Fabry and Gaucher disease.
Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Creatine; Fabry Disease; Female; Gaucher Diseas | 2011 |
Proton magnetic resonance spectroscopic imaging in childhood ataxia with diffuse central nervous system hypomyelination.
Topics: Aspartic Acid; Ataxia; Brain; Brain Diseases; Child, Preschool; Choline; Creatine; Female; Gaucher D | 1995 |
Gaucher type 2 disease: identification of a novel transversion mutation in a French-Irish patient.
Topics: Aspartic Acid; Female; France; Gaucher Disease; Glucosylceramidase; Humans; Infant; Ireland; Lysine; | 1998 |