aspartic acid has been researched along with Gangliosidosis, GM1 in 3 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Gangliosidosis, GM1: An autosomal recessive neurodegenerative disorder caused by the absence or deficiency of BETA-GALACTOSIDASE. It is characterized by intralysosomal accumulation of G(M1) GANGLIOSIDE and oligosaccharides, primarily in neurons of the central nervous system. The infantile form is characterized by MUSCLE HYPOTONIA, poor psychomotor development, HIRSUTISM, hepatosplenomegaly, and facial abnormalities. The juvenile form features HYPERACUSIS; SEIZURES; and psychomotor retardation. The adult form features progressive DEMENTIA; ATAXIA; and MUSCLE SPASTICITY. (From Menkes, Textbook of Child Neurology, 5th ed, pp96-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Background GM1 gangliosidosis is a lysosomal storage disorder caused by mutations in GLB1, encoding β-galactosidase." | 1.43 | MRI/MRS as a surrogate marker for clinical progression in GM1 gangliosidosis. ( Adams, D; Baker, EH; Golas, G; Johnston, J; Kwon, HJ; Latour, Y; Portner, C; Regier, DS; Thomas, S; Tifft, CJ; Vezina, G; Wiggs, E; Yang, S, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Regier, DS | 1 |
| Kwon, HJ | 1 |
| Johnston, J | 1 |
| Golas, G | 1 |
| Yang, S | 1 |
| Wiggs, E | 1 |
| Latour, Y | 1 |
| Thomas, S | 1 |
| Portner, C | 1 |
| Adams, D | 1 |
| Vezina, G | 1 |
| Baker, EH | 1 |
| Tifft, CJ | 1 |
| Brunetti-Pierri, N | 1 |
| Bhattacharjee, MB | 1 |
| Wang, ZJ | 1 |
| Wenger, DA | 1 |
| Potocki, L | 1 |
| Hunter, J | 1 |
| Scaglia, F | 1 |
| Zhang, S | 1 |
| Bagshaw, R | 1 |
| Hilson, W | 1 |
| Oho, Y | 1 |
| Hinek, A | 1 |
| Clarke, JT | 1 |
| Callahan, JW | 1 |
3 other studies available for aspartic acid and Gangliosidosis, GM1
| Article | Year |
|---|---|
MRI/MRS as a surrogate marker for clinical progression in GM1 gangliosidosis.
Topics: Adolescent; Age of Onset; Aspartic Acid; Atrophy; beta-Galactosidase; Cerebellum; Cerebrum; Child; C | 2016 |
Brain proton magnetic resonance spectroscopy and neuromuscular pathology in a patient with GM1 gangliosidosis.
Topics: Aspartic Acid; Axons; Biomarkers; Brain; Female; Gangliosidosis, GM1; Gliosis; Humans; Infant; Inosi | 2008 |
Characterization of beta-galactosidase mutations Asp332-->Asn and Arg148-->Ser, and a polymorphism, Ser532-->Gly, in a case of GM1 gangliosidosis.
Topics: Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Base Sequence; beta-Galactosi | 2000 |