aspartic acid has been researched along with Epilepsy, Tonic-Clonic in 9 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Valproate (VPA) interferes with mitochondrial metabolism causing hyperammonemia, thereby shifting the balance reaction of glutamine (Gln)/glutamate (Glu) toward Gln." | 3.75 | Valproate-induced metabolic changes in patients with epilepsy: assessment with H-MRS. ( Buechert, M; Garcia, M; Huppertz, HJ; Mader, I; Schumacher, M; Ziyeh, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garcia, M | 1 |
| Huppertz, HJ | 1 |
| Ziyeh, S | 1 |
| Buechert, M | 1 |
| Schumacher, M | 1 |
| Mader, I | 1 |
| Kumar, V | 1 |
| Chakrabarti, S | 1 |
| Modi, M | 1 |
| Sahoo, M | 1 |
| Doelken, MT | 1 |
| Mennecke, A | 1 |
| Stadlbauer, A | 1 |
| Kecskeméti, L | 1 |
| Kasper, BS | 1 |
| Struffert, T | 1 |
| Doerfler, A | 1 |
| Stefan, H | 2 |
| Hammen, T | 1 |
| González-Ramírez, M | 1 |
| Razo-Juárez, LI | 1 |
| Sauer-Ramírez, JL | 1 |
| González-Trujano, ME | 1 |
| Salgado-Ceballos, H | 1 |
| Orozco-Suarez, S | 1 |
| Wang, M | 1 |
| Li, S | 1 |
| Zhou, G | 1 |
| Liao, W | 1 |
| Li, G | 1 |
| Xiao, B | 1 |
| Savic, I | 1 |
| Osterman, Y | 1 |
| Helms, G | 1 |
| Yamamoto, A | 1 |
| Takagi, H | 1 |
| Kitamura, D | 1 |
| Tatsuoka, H | 1 |
| Nakano, H | 1 |
| Kawano, H | 1 |
| Kuroyanagi, H | 1 |
| Yahagi, Y | 1 |
| Kobayashi, S | 1 |
| Koizumi, K | 1 |
| Sakai, T | 1 |
| Saito, K | 1 |
| Chiba, T | 1 |
| Kawamura, K | 1 |
| Suzuki, K | 1 |
| Watanabe, T | 1 |
| Mori, H | 1 |
| Shirasawa, T | 1 |
| Janjua, NA | 1 |
| Kabuto, H | 1 |
| Mori, A | 1 |
| Schüler, P | 1 |
| Schuierer, G | 1 |
| Hentschel, D | 1 |
| Ladebeck, R | 1 |
| Wittig, R | 1 |
| Huk, W | 1 |
| Neundörfer, B | 1 |
1 review available for aspartic acid and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
Deficiency in protein L-isoaspartyl methyltransferase results in a fatal progressive epilepsy.
Topics: Animals; Aspartic Acid; Brain; Disease Progression; Epilepsy; Epilepsy, Tonic-Clonic; Mice; Mice, In | 1998 |
8 other studies available for aspartic acid and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
Valproate-induced metabolic changes in patients with epilepsy: assessment with H-MRS.
Topics: Adolescent; Adult; Anticonvulsants; Aspartic Acid; Choline; Creatine; Energy Metabolism; Epilepsies, | 2009 |
Late-onset obsessive compulsive disorder associated with possible gliomatosis cerebri.
Topics: Aged; Anticonvulsants; Aspartic Acid; Brain Neoplasms; Choline; Corpus Callosum; Dominance, Cerebral | 2009 |
Multi-voxel magnetic resonance spectroscopy at 3 T in patients with idiopathic generalised epilepsy.
Topics: Adolescent; Adult; Aspartic Acid; Basal Ganglia; Brain; Cerebral Cortex; Choline; Creatine; Epilepsy | 2010 |
Anticonvulsive effect of vitamin C on pentylenetetrazol-induced seizures in immature rats.
Topics: Animals; Anticonvulsants; Ascorbic Acid; Aspartic Acid; Brain Chemistry; Chromatography, High Pressu | 2010 |
[(1)H-magnetic resonance spectroscopy on bilateral thalamus of patients with secondarily generalized tonic-clonic seizures].
Topics: Adolescent; Adult; Aspartic Acid; Brain Chemistry; Case-Control Studies; Choline; Energy Metabolism; | 2012 |
MRS shows syndrome differentiated metabolite changes in human-generalized epilepsies.
Topics: Adolescent; Adult; Aspartic Acid; Cerebellum; Cerebral Cortex; Choline; Creatine; Dominance, Cerebra | 2004 |
Increased plasma glutamic acid in a genetic model of epilepsy.
Topics: Animals; Aspartic Acid; Disease Susceptibility; Epilepsy, Tonic-Clonic; Glutamates; Glutamic Acid; M | 1992 |
[4-Tesla 1H MR spectroscopy in patients with temporal lobe epilepsy].
Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Energy Metabolism; Epilepsies, Partial; Epileps | 1991 |