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aspartic acid and Epilepsy, Temporal Lobe

aspartic acid has been researched along with Epilepsy, Temporal Lobe in 113 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to quantitate and compare ipsilateral total N-acetyl aspartate (tNAA), creatine (Cr), choline (Cho), myo-inositol (m-Ins) and glutamate plus glutamine (Glx) levels in the hippocampi of patients with temporal lobe epilepsy (TLE) with and without magnetic resonance imaging (MRI) evidence for mesial temporal sclerosis (MRI positive/negative)."3.74(1)H-MRS profile in MRI positive- versus MRI negative patients with temporal lobe epilepsy. ( Doelken, MT; Doerfler, A; Engelhorn, T; Ganslandt, O; Hammen, T; Pauli, E; Richter, G; Stadlbauer, A; Stefan, H; Struffert, T, 2008)
"Mesial temporal lobe epilepsy (mTLE) is characterized by hippocampal atrophy, decreased N-acetyl-aspartate, and a low N-acetyl-aspartate/total creatine ratio, often attributed to neuron loss and gliosis."3.72N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus. ( Errante, LD; Kim, JH; Petroff, OA; Spencer, DD, 2003)
"We investigated myoinositol in TLE by using short-echo MRS in 34 TLE patients [26 late onset (LO-TLE), eight hippocampal sclerosis (HS-TLE)], and 16 controls."3.72Myoinositol abnormalities in temporal lobe epilepsy. ( Briellmann, RS; Jackson, GD; Prichard, JW; Syngeniotis, A; Wellard, RM, 2003)
"Temporal lobe epilepsy was associated with bilateral reduction in NAAt/Cr but not significant abnormality in GABA+/Cr or GLX/Cr."2.74Proton MR spectroscopy of metabolite concentrations in temporal lobe epilepsy and effect of temporal lobe resection. ( Barker, GJ; Duncan, JS; McLean, MA; Simister, RJ, 2009)
"Linear regression analyses between seizure duration and NAA/Cr decrease was not significant."2.69Medial temporal lobe neuronal damage in temporal and extratemporal lesional epilepsy. ( Andermann, F; Arnold, DL; Cendes, F; Dubeau, F; Li, LM; Miller, SP; Tasch, E, 2000)
"Seizures were analyzed by: number of clinical seizures in 24 h, exact duration of clinical symptoms in 24 h, frequency of interictal epileptiform discharges (IEDs) and ictal activity, duration of ictal activity, and IEDs occurring within 24 h in intensive EEG monitoring."1.341H-MR spectroscopy indicates severity markers in temporal lobe epilepsy: correlations between metabolic alterations, seizures, and epileptic discharges in EEG. ( Doelken, M; Doerfler, A; Engelhorn, T; Ganslandt, O; Hammen, T; Kerling, F; Nimsky, C; Schwarz, M; Stadlbauer, A; Stefan, H, 2007)
"Our results demonstrate effects of seizures on the hippocampi in neocortical epilepsy and the relation between SGTCS and NAA/Cr of the contralateral hippocampus in mTLE."1.33Effect of seizure on hippocampus in mesial temporal lobe epilepsy and neocortical epilepsy: an MRS study. ( Chang, KH; Chung, CK; Kim, DW; Kim, KK; Lee, SK; Song, IC, 2005)
"Mesial temporal lobe epilepsy is characterized by hippocampal atrophy, hypometabolism, and decreased N-acetylaspartate, often attributed to neuron loss and gliosis."1.31Neuronal and glial metabolite content of the epileptogenic human hippocampus. ( Errante, LD; Kim, JH; Petroff, OA; Rothman, DL; Spencer, DD, 2002)
"The creatine content was the same in biopsied epileptic cortex (8."1.29Symbiosis between in vivo and in vitro NMR spectroscopy: the creatine, N-acetylaspartate, glutamate, and GABA content of the epileptic human brain. ( Petroff, OA; Pleban, LA; Spencer, DD, 1995)

Research

Studies (113)

TimeframeStudies, this research(%)All Research%
pre-19903 (2.65)18.7374
1990's37 (32.74)18.2507
2000's62 (54.87)29.6817
2010's8 (7.08)24.3611
2020's3 (2.65)2.80

Authors

AuthorsStudies
Nakamura, Y1
Inoue, A1
Nishikawa, M1
Ohnishi, T1
Yano, H1
Kanemura, Y1
Ohtsuka, Y1
Ozaki, S1
Kusakabe, K1
Suehiro, S1
Yamashita, D1
Shigekawa, S1
Watanabe, H1
Kitazawa, R1
Tanaka, J1
Kunieda, T1
He, C1
Liu, P1
Wu, Y2
Chen, H1
Song, Y1
Yin, J1
Fernández-Vega, N1
Ramos-Rodriguez, JR1
Alfaro, F1
Barbancho, MÁ1
García-Casares, N1
Meller, S1
Brandt, C1
Theilmann, W1
Klein, J1
Löscher, W1
Pan, JW6
Duckrow, RB1
Gerrard, J1
Ong, C1
Hirsch, LJ1
Resor, SR1
Zhang, Y1
Petroff, O1
Spencer, S1
Hetherington, HP7
Spencer, DD7
Pearce, PS1
Rapuano, A1
Hitchens, TK1
de Lanerolle, NC2
Pimentel-Silva, LR1
Cendes, F10
Fadaie, F1
Mobarakeh, NM1
Fesharaki, SS1
Harirchian, MH1
Kharazi, HH1
Rad, HS1
Habibabadi, JM1
Brázdil, M1
Marecek, R1
Fojtíková, D1
Mikl, M1
Kuba, R1
Krupa, P1
Rektor, I1
Simister, RJ2
McLean, MA2
Barker, GJ2
Duncan, JS4
Campos, BA1
Yasuda, CL1
Castellano, G1
Bilevicius, E1
Li, LM8
Mantoan, MA1
Caboclo, LO1
de Figueiredo Ferreira Guilhoto, LM1
Lin, K1
da Silva Noffs, MH1
de Souza Silva Tudesco, I1
Belzunces, E1
Carrete, H1
Bussoletti, RT1
Centeno, RS1
Sakamoto, AC1
Yacubian, EM1
Mueller, SG3
Ebel, A1
Barakos, J1
Scanlon, C1
Cheong, I1
Finlay, D1
Garcia, P1
Weiner, MW12
Laxer, KD12
Fountas, KN1
Tsougos, I1
Gotsis, ED1
Giannakodimos, S1
Smith, JR1
Kapsalaki, EZ1
Vermathen, P6
Ende, G2
Walker, JA1
Knowlton, RC4
Barbaro, NM2
Matson, GB8
Woermann, FG1
Bartlett, PA1
Capizzano, AA3
Maudsley, AA3
Soher, BJ1
Schuff, NW1
Guye, M1
Le Fur, Y1
Confort-Gouny, S1
Ranjeva, JP1
Bartolomei, F1
Régis, J1
Raybaud, CA1
Chauvel, P1
Cozzone, PJ1
Suhy, J3
Flenniken, DL2
Axelrad, J1
Petroff, OA3
Errante, LD2
Rothman, DL1
Kim, JH4
Park, SA1
Kim, GS1
Lee, SK3
Lim, SR1
Heo, K1
Park, SC1
Chang, JW1
Kim, DI1
Lee, BI1
Schuff, N2
Klitgaard, H1
Matagne, A1
Grimee, R1
Vanneste-Goemaere, J1
Margineanu, DG1
Hájek, M3
Dezortová, M3
Liscák, R1
Vymazal, J1
Vladyka, V1
Thomas, PM3
Phillips, JP3
Delanty, N1
O'Connor, WT3
Wellard, RM1
Briellmann, RS2
Prichard, JW1
Syngeniotis, A1
Jackson, GD5
Lopez, RC1
Jírů, F1
Burian, M1
Vielhaber, S2
Kudin, AP2
Kudina, TA1
Stiller, D1
Scheich, H1
Schoenfeld, A1
Feistner, H1
Heinze, HJ2
Elger, CE2
Kunz, WS2
Shih, JJ1
Weisend, MP1
Lewine, J1
Sanders, J1
Dermon, J1
Lee, R1
Hanoğlu, L1
Ozkara, C1
Keskinkiliç, C1
Altin, U1
Uzan, M1
Tuzgen, S1
Dinçer, A1
Ozyurt, E1
Cohen-Gadol, AA1
Hetherington, HH1
Burneo, JG1
Faught, E5
Martin, R1
Sawrie, S2
Kuzniecky, RI7
Spencer, DC1
Szumowski, J1
Kraemer, DF1
Wang, PY1
Burchiel, KJ1
Spielman, DM1
Kim, DW1
Kim, KK1
Chung, CK2
Song, IC2
Chang, KH2
Riederer, F2
Bittsanský, M2
Schmidt, C1
Mlynárik, V2
Baumgartner, C2
Moser, E2
Serles, W5
Lantz, G1
Seeck, M1
Lazeyras, F1
Lu, JJ1
Ren, LK1
Feng, F1
You, H1
Zhang, LH1
Li, ML1
Sun, F1
Fu, HH1
Jin, ZY1
Gilliam, FG2
Maton, BM2
Martin, RC3
Sawrie, SM2
Faught, RE1
Hugg, JW4
Viikinsalo, M1
Hammen, T3
Schwarz, M1
Doelken, M2
Kerling, F2
Engelhorn, T3
Stadlbauer, A3
Ganslandt, O3
Nimsky, C2
Doerfler, A3
Stefan, H7
Mark Wellard, R1
Masterton, RA1
Abbott, DF1
Berkovic, SF1
Gomes, WA1
Lado, FA1
Takahashi, K1
Pan, C1
Niessen, HG1
Debska-Vielhaber, G1
Wellmer, J1
Kaufmann, J1
Schönfeld, MA1
Fendrich, R1
Willker, W1
Leibfritz, D1
Schramm, J1
Lehner-Baumgartner, E1
Gruber, S1
Kaya, M1
Hildebrandt, M1
Kasper, B1
Romstoeck, J1
Blumcke, I1
Vives, K1
Devinsky, O1
Pacia, S1
Luciano, D1
Vasquez, B1
Haut, S1
Doelken, MT1
Pauli, E3
Struffert, T1
Richter, G1
Engelsen, B1
Elsayed, S1
Hetherington, H1
Kuzniecky, R3
Pan, J1
Mason, G1
Morawetz, R1
Harris, C1
Vaughan, T1
Pohost, G1
Giroud, M1
Walker, P1
Bernard, D1
Fayolle, H1
Beaurain, J1
Baudoin, N1
Brunotte, F1
Dumas, R1
Vainio, P1
Usenius, JP1
Vapalahti, M1
Partanen, K1
Kälviäinen, R1
Rinne, J1
Kauppinen, RA1
Ng, TC2
Comair, YG2
Xue, M1
So, N1
Majors, A1
Kolem, H1
Luders, H1
Modic, M1
Connelly, A3
King, MD1
Gadian, DG4
Peeling, J1
Sutherland, G1
Andermann, F9
Preul, MC1
Arnold, DL10
Breiter, SN1
Arroyo, S1
Mathews, VP1
Lesser, RP1
Bryan, RN1
Barker, PB1
Cross, JH2
Johnson, CL2
Neville, BG2
Vaughan, JT1
Twieg, DB1
Pohost, GM1
Pleban, LA1
Morawetz, RB1
Fraught, RE1
Lu, D1
Margouleff, C1
Rubin, E1
Labar, D1
Schaul, N1
Ishikawa, T1
Kazumata, K1
Antonini, A1
Dhawan, V1
Hyman, RA1
Eidelberg, D1
Najm, IM1
Wang, Y1
Hong, SC1
Lüders, HO1
Tokumitsu, T1
Mancuso, A1
Weinstein, PR1
Naruse, S1
Ende, GR1
Fein, G1
Gordon, I1
Caramanos, Z3
Dubeau, F7
Matthews, PM1
Thompson, JE1
Castillo, M2
Kwock, L2
Walters, B1
Beach, R1
Mendes-Ribeiro, JA1
Soares, R1
Simões-Ribeiro, F1
Guimarães, ML1
Duc, CO1
Trabesinger, AH1
Weber, OM1
Meier, D1
Walder, M1
Wieser, HG1
Boesiger, P1
Komárek, V1
Choi, CG1
Frahm, J1
Bakken, IJ1
Axelson, D1
Kvistad, KA1
Brodtkorb, E1
Müller, B1
Aasly, J1
Gribbestad, IS1
Namer, IJ1
Bolo, NR1
Sellal, F1
Nguyen, VH1
Nedelec, JF1
Hirsch, E1
Marescaux, C1
Hugg, J1
Gilliam, F3
Eberhardt, KE2
Grabenbauer, GG1
Schäfer, I3
Tomandl, B2
Huk, WJ2
Kreisler, P1
Käferlein, M1
Gotman, J2
Antel, SB2
Olivier, A3
Meiners, LC1
van der Grond, J1
van Rijen, PC1
Springorum, R1
de Kort, GA1
Jansen, GH1
Chu, WJ1
Abou-Khalil, B1
Miller, SP2
Tasch, E1
Rosenblatt, B1
Shevell, MI1
Hopp, P1
Someya, Y1
Obata, T1
Suhara, T1
Ota, Y1
Ikehira, H1
Tanada, S1
Hirakawa, K1
Okubo, Y1
Sasaki, Y1
Maier, M1
Mellers, J1
Toone, B1
Trimble, M1
Ron, MA1
Smith, JK1
Park, SW1
Kim, HD1
Lee, DS1
Yu, IK1
Han, MH1
Park, YH1
Feichtinger, M1
Eberhardt, KW1
Huk, J1
Kikuchi, S1
Kubota, F1
Hattori, S1
Oya, N1
Mikuni, M1
Vikhoff-Baaz, B1
Malmgren, K1
Jönsson, L1
Starck, G1
Ljungberg, M1
Forssell-Aronsson, E1
Uvebrant, P1
Ekholm, S1
Hsu, YY1
Chang, CN1
Chu, NS1
Lim, KE1
Chang, C1
Hsu, JC1
Knowlton, R1
Kantarci, K1
Shin, C1
Britton, JW1
So, EL1
Cascino, GD1
Jack, CR1
Schwarcz, R1
Du, F1
Schüler, P1
Schuierer, G1
Hentschel, D1
Ladebeck, R1
Wittig, R1
Huk, W1
Neundörfer, B1
Meldrum, BS1
Avoli, M1
Kish, SJ1
Dixon, LM1
Sherwin, AL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neuroimaging Predictors of Treatment Failure in Adult New-onset Epilepsy[NCT01320670]50 participants (Anticipated)Observational2011-06-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for aspartic acid and Epilepsy, Temporal Lobe

ArticleYear
Usefulness of magnetic resonance spectroscopy in mesial temporal sclerosis: a systematic review.
    Neuroradiology, 2021, Volume: 63, Issue:9

    Topics: Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; Hippocampus; Humans; Magnetic Resonance I

2021
Magnetic resonance spectroscopy.
    Epilepsia, 1996, Volume: 37, Issue:7

    Topics: Aspartic Acid; Brain; Creatinine; Epilepsy; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; gamm

1996
Application of high field spectroscopic imaging in the evaluation of temporal lobe epilepsy.
    Magnetic resonance imaging, 1995, Volume: 13, Issue:8

    Topics: Aspartic Acid; Brain Mapping; Creatine; Dominance, Cerebral; Energy Metabolism; Epilepsy, Temporal L

1995
Clinical applications of magnetic resonance spectroscopy.
    Epilepsia, 1997, Volume: 38 Suppl 4

    Topics: Aspartic Acid; Brain; Brain Mapping; Epilepsy; Epilepsy, Frontal Lobe; Epilepsy, Temporal Lobe; Fron

1997
1H MR spectroscopy in patients with mesial temporal epilepsy.
    Magma (New York, N.Y.), 1998, Volume: 7, Issue:2

    Topics: Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; G

1998
Proton MRS: N-acetyl aspartate, creatine, and choline.
    Advances in neurology, 2000, Volume: 83

    Topics: Aspartic Acid; Brain; Choline; Creatine; Epilepsy, Temporal Lobe; Humans; Magnetic Resonance Spectro

2000
Quinolinic acid and kynurenic acid in the mammalian brain.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; AIDS Dementia Complex; Animals; Aspartic Acid; Biological Tra

1991
Excitatory amino acid transmitters in epilepsy.
    Epilepsia, 1991, Volume: 32 Suppl 2

    Topics: Anticonvulsants; Aspartic Acid; Epilepsy; Epilepsy, Temporal Lobe; Glutamates; Glutamic Acid; Humans

1991

Trials

10 trials available for aspartic acid and Epilepsy, Temporal Lobe

ArticleYear
Proton MR spectroscopy of metabolite concentrations in temporal lobe epilepsy and effect of temporal lobe resection.
    Epilepsy research, 2009, Volume: 83, Issue:2-3

    Topics: Adolescent; Adult; Aspartic Acid; Brain Chemistry; Brain Mapping; Carnosine; Creatine; Epilepsy, Tem

2009
Temporal lobectomy for epilepsy: recovery of the contralateral hippocampus measured by (1)H MRS.
    Neurology, 2002, Aug-27, Volume: 59, Issue:4

    Topics: Adult; Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Functional Laterality; Hip

2002
A short-echo-time proton magnetic resonance spectroscopic imaging study of temporal lobe epilepsy.
    Epilepsia, 2002, Volume: 43, Issue:9

    Topics: Adult; Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Functional Laterality; Glu

2002
Elevated extracellular levels of glutamate, aspartate and gamma-aminobutyric acid within the intraoperative, spontaneously epileptiform human hippocampus.
    Epilepsy research, 2003, Volume: 54, Issue:1

    Topics: Adult; Anesthesia, General; Aspartic Acid; Electroencephalography; Epilepsy, Temporal Lobe; Female;

2003
The role of relaxation time corrections for the evaluation of long and short echo time 1H MR spectra of the hippocampus by NUMARIS and LCModel techniques.
    Magma (New York, N.Y.), 2003, Volume: 16, Issue:3

    Topics: Adult; Algorithms; Aspartic Acid; Brain Mapping; Choline; Creatine; Diagnosis, Computer-Assisted; Ep

2003
Mesial temporal lobe epilepsy: a proton magnetic resonance spectroscopy study and a histopathological analysis.
    Journal of neurosurgery, 2004, Volume: 101, Issue:4

    Topics: Adult; Aspartic Acid; Child; Creatine; Epilepsy, Temporal Lobe; Female; Hippocampus; Humans; Magneti

2004
Temporal lobe magnetic resonance spectroscopic imaging following selective amygdalohippocampectomy for treatment-resistant epilepsy.
    Acta neurologica Scandinavica, 2005, Volume: 112, Issue:1

    Topics: Adult; Amygdala; Aspartic Acid; Brain Chemistry; Creatine; Epilepsy, Temporal Lobe; Female; Hippocam

2005
Reduced N-acetylaspartate concentration in temporal lobe epilepsy by quantitative 1H MRS in vivo.
    Neuroreport, 1994, Sep-08, Volume: 5, Issue:14

    Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Electroencephalography; Epilepsy, Temporal Lobe

1994
Applications of neural network analyses to in vivo 1H magnetic resonance spectroscopy of epilepsy patients.
    Epilepsy research, 1999, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Electroencephalography; Epilep

1999
Medial temporal lobe neuronal damage in temporal and extratemporal lesional epilepsy.
    Neurology, 2000, Apr-11, Volume: 54, Issue:7

    Topics: Action Potentials; Adolescent; Adult; Analysis of Variance; Aspartic Acid; Brain Neoplasms; Child; C

2000

Other Studies

95 other studies available for aspartic acid and Epilepsy, Temporal Lobe

ArticleYear
Quantitative measurement of peritumoral concentrations of glutamate, N-acetyl aspartate, and lactate on magnetic resonance spectroscopy predicts glioblastoma-related refractory epilepsy.
    Acta neurochirurgica, 2022, Volume: 164, Issue:12

    Topics: Aspartic Acid; Creatine; Drug Resistant Epilepsy; Epilepsy, Temporal Lobe; Glioblastoma; Glutamic Ac

2022
Gamma-aminobutyric acid (GABA) changes in the hippocampus and anterior cingulate cortex in patients with temporal lobe epilepsy.
    Epilepsy & behavior : E&B, 2021, Volume: 115

    Topics: Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Gyrus Cinguli; H

2021
Commonalities and differences in extracellular levels of hippocampal acetylcholine and amino acid neurotransmitters during status epilepticus and subsequent epileptogenesis in two rat models of temporal lobe epilepsy.
    Brain research, 2019, 06-01, Volume: 1712

    Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Disease Models, Animal; Electroencephalography;

2019
7T MR spectroscopic imaging in the localization of surgical epilepsy.
    Epilepsia, 2013, Volume: 54, Issue:9

    Topics: Adolescent; Adult; Aspartic Acid; Creatine; Electroencephalography; Epilepsy, Temporal Lobe; Female;

2013
Metabolic changes in early poststatus epilepticus measured by MR spectroscopy in rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2015, Volume: 35, Issue:11

    Topics: Animals; Antigens, Nuclear; Aspartic Acid; Brain Chemistry; Creatine; Epilepsy, Temporal Lobe; Gluta

2015
Phosphorus magnetic resonance spectroscopy in the investigation of temporal lobe epilepsy: 'reading between the lines' of metabolic abnormalities.
    Arquivos de neuro-psiquiatria, 2016, Volume: 74, Issue:2

    Topics: Aspartic Acid; Electroencephalography; Epilepsy, Temporal Lobe; Hippocampus; Humans; Magnetic Resona

2016
1H-MRS metabolite's ratios show temporal alternation in temporal lobe seizure: Comparison between interictal and postictal phases.
    Epilepsy research, 2016, Volume: 128

    Topics: Adult; Aspartic Acid; Choline; Creatinine; Drug Resistant Epilepsy; Electroencephalography; Epilepsy

2016
Correlation study of optimized voxel-based morphometry and (1)H MRS in patients with mesial temporal lobe epilepsy and hippocampal sclerosis.
    Human brain mapping, 2009, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Brain Mapping; Case-Control Studies; Choline; Creatine; Electroenc

2009
Proton MRS may predict AED response in patients with TLE.
    Epilepsia, 2010, Volume: 51, Issue:5

    Topics: Adult; Anticonvulsants; Aspartic Acid; Drug Resistance; Drug Therapy, Combination; Electroencephalog

2010
Correlation between memory, proton magnetic resonance spectroscopy, and interictal epileptiform discharges in temporal lobe epilepsy related to mesial temporal sclerosis.
    Epilepsy & behavior : E&B, 2009, Volume: 16, Issue:3

    Topics: Adult; Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Functional Laterality; Hum

2009
Widespread extrahippocampal NAA/(Cr+Cho) abnormalities in TLE with and without mesial temporal sclerosis.
    Journal of neurology, 2011, Volume: 258, Issue:4

    Topics: Adult; Aspartic Acid; Brain Mapping; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Humans; Mag

2011
Temporal pole proton preoperative magnetic resonance spectroscopy in patients undergoing surgery for mesial temporal sclerosis.
    Neurosurgical focus, 2012, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Functional Lat

2012
Multisection proton MR spectroscopy for mesial temporal lobe epilepsy.
    AJNR. American journal of neuroradiology, 2002, Volume: 23, Issue:8

    Topics: Adult; Aspartic Acid; Brain; Case-Control Studies; Choline; Creatine; Epilepsy, Temporal Lobe; Femal

2002
Metabolic and electrophysiological alterations in subtypes of temporal lobe epilepsy: a combined proton magnetic resonance spectroscopic imaging and depth electrodes study.
    Epilepsia, 2002, Volume: 43, Issue:10

    Topics: Adolescent; Adult; Amygdala; Aspartic Acid; Choline; Electrodes, Implanted; Electroencephalography;

2002
Reduced extrahippocampal NAA in mesial temporal lobe epilepsy.
    Epilepsia, 2002, Volume: 43, Issue:10

    Topics: Adult; Aspartic Acid; Brain; Electroencephalography; Epilepsy, Temporal Lobe; Female; Frontal Lobe;

2002
Neuronal and glial metabolite content of the epileptogenic human hippocampus.
    Annals of neurology, 2002, Volume: 52, Issue:5

    Topics: Adult; Amino Acids; Aspartic Acid; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Glutami

2002
Interictal epileptiform discharges relate to 1H-MRS-detected metabolic abnormalities in mesial temporal lobe epilepsy.
    Epilepsia, 2002, Volume: 43, Issue:11

    Topics: Adult; Aspartic Acid; Creatine; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Mag

2002
Evidence of neuronal injury outside the medial temporal lobe in temporal lobe epilepsy: N-acetylaspartate concentration reductions detected with multisection proton MR spectroscopic imaging--initial experience.
    Radiology, 2003, Volume: 226, Issue:1

    Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine Kinase; Epilepsy, Temporal Lobe; Female; Hi

2003
Electrophysiological, neurochemical and regional effects of levetiracetam in the rat pilocarpine model of temporal lobe epilepsy.
    Seizure, 2003, Volume: 12, Issue:2

    Topics: Animals; Anticonvulsants; Aspartic Acid; Clonazepam; Electroencephalography; Epilepsy, Temporal Lobe

2003
1H MR spectroscopy of mesial temporal lobe epilepsies treated with Gamma knife.
    European radiology, 2003, Volume: 13, Issue:5

    Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Fo

2003
N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus.
    Neurology, 2003, May-27, Volume: 60, Issue:10

    Topics: Adolescent; Adult; Anterior Temporal Lobectomy; Aspartic Acid; Atrophy; Creatine; Epilepsy, Temporal

2003
Myoinositol abnormalities in temporal lobe epilepsy.
    Epilepsia, 2003, Volume: 44, Issue:6

    Topics: Adult; Age of Onset; Aspartic Acid; Epilepsy, Temporal Lobe; Female; Frontal Lobe; Functional Latera

2003
Spectroscopic metabolic abnormalities in mTLE with and without MRI evidence for mesial temporal sclerosis using hippocampal short-TE MRSI.
    Epilepsia, 2003, Volume: 44, Issue:7

    Topics: Adult; Aspartic Acid; Choline; Creatine; Diagnosis, Differential; Dominance, Cerebral; Energy Metabo

2003
Hippocampal N-acetyl aspartate levels do not mirror neuronal cell densities in creatine-supplemented epileptic rats.
    The European journal of neuroscience, 2003, Volume: 18, Issue:8

    Topics: Animals; Anticonvulsants; Aspartic Acid; Cell Count; Creatine; Diazepam; Disease Models, Animal; Epi

2003
Hippocampal microdialysis during spontaneous intraoperative epileptiform activity.
    Acta neurochirurgica, 2004, Volume: 146, Issue:2

    Topics: Adult; Aspartic Acid; Dominance, Cerebral; Electroencephalography; Epilepsy, Temporal Lobe; Female;

2004
Areas of interictal spiking are associated with metabolic dysfunction in MRI-negative temporal lobe epilepsy.
    Epilepsia, 2004, Volume: 45, Issue:3

    Topics: Adolescent; Adult; Aspartic Acid; Biomarkers; Brain; Choline; Electroencephalography; Epilepsy, Temp

2004
Correlation between 1H MRS and memory before and after surgery in mesial temporal lobe epilepsy with hippocampal sclerosis.
    Epilepsia, 2004, Volume: 45, Issue:6

    Topics: Adolescent; Adult; Aspartic Acid; Brain Mapping; Choline; Creatinine; Electroencephalography; Epilep

2004
1H and 31P spectroscopic imaging of epilepsy: spectroscopic and histologic correlations.
    Epilepsia, 2004, Volume: 45 Suppl 4

    Topics: Adult; Amygdala; Aspartic Acid; Brain; Choline; Creatine; Epilepsy; Epilepsy, Temporal Lobe; Female;

2004
Chronic temporal lobe epilepsy: spatial extent and degree of metabolic dysfunction studied with magnetic resonance spectroscopy (MRS).
    Epilepsy research, 2004, Volume: 62, Issue:2-3

    Topics: Adolescent; Adult; Aspartic Acid; Child; Child, Preschool; Chronic Disease; Creatine; Electroencepha

2004
Microdialysis of the lateral and medial temporal lobe during temporal lobe epilepsy surgery.
    Surgical neurology, 2005, Volume: 63, Issue:1

    Topics: Action Potentials; Adult; Aspartic Acid; Electroencephalography; Epilepsy, Temporal Lobe; Extracellu

2005
Effect of seizure on hippocampus in mesial temporal lobe epilepsy and neocortical epilepsy: an MRS study.
    Neuroradiology, 2005, Volume: 47, Issue:12

    Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Epilepsy, Temporal Lobe; Female; Hippocampus; H

2005
1H magnetic resonance spectroscopy at 3 T in cryptogenic and mesial temporal lobe epilepsy.
    NMR in biomedicine, 2006, Volume: 19, Issue:5

    Topics: Adult; Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Glutamic Acid; Glutamine;

2006
Extent of preoperative abnormalities and focus lateralization predict postoperative normalization of contralateral 1H-magnetic resonance spectroscopy metabolite levels in patients with temporal lobe epilepsy.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:8

    Topics: Adult; Aspartic Acid; Atrophy; Choline; Creatine; Dominance, Cerebral; Electroencephalography; Energ

2006
Metabolic abnormalities in mesial temporal lobe epilepsy patients depicted by proton MR spectroscopy using a 3. 0t MR scanner.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2006, Volume: 21, Issue:4

    Topics: Adult; Aspartic Acid; Choline; Creatine; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hi

2006
Hippocampal 1H-MRSI correlates with severity of depression symptoms in temporal lobe epilepsy.
    Neurology, 2007, Jan-30, Volume: 68, Issue:5

    Topics: Adult; Aspartic Acid; Biomarkers; Creatine; Depression; Epilepsy, Temporal Lobe; Female; Hippocampus

2007
1H-MR spectroscopy indicates severity markers in temporal lobe epilepsy: correlations between metabolic alterations, seizures, and epileptic discharges in EEG.
    Epilepsia, 2007, Volume: 48, Issue:2

    Topics: Adult; Aspartic Acid; Biomarkers; Brain Mapping; Choline; Creatine; Dipeptides; Electroencephalograp

2007
Hippocampal sclerosis: MR prediction of seizure intractability.
    Epilepsia, 2007, Volume: 48, Issue:2

    Topics: Adult; Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Functional Laterality; Glu

2007
Spectroscopic imaging of the pilocarpine model of human epilepsy suggests that early NAA reduction predicts epilepsy.
    Magnetic resonance in medicine, 2007, Volume: 58, Issue:2

    Topics: Animals; Aspartic Acid; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Humans; Image

2007
Subfield-specific loss of hippocampal N-acetyl aspartate in temporal lobe epilepsy.
    Epilepsia, 2008, Volume: 49, Issue:1

    Topics: Aconitate Hydratase; Adult; Aged; Aspartic Acid; Cell Count; Electroencephalography; Epilepsy, Tempo

2008
Decrease of NAA with aging outside the seizure focus in mesial temporal lobe epilepsy--a proton-MRS study at 3 Tesla.
    Brain research, 2007, Nov-07, Volume: 1179

    Topics: Adolescent; Adult; Aging; Aspartic Acid; Choline; Creatine; Drug Resistance; Epilepsy, Temporal Lobe

2007
Non-invasive detection of hippocampal sclerosis: correlation between metabolite alterations detected by (1)H-MRS and neuropathology.
    NMR in biomedicine, 2008, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Aspartic Acid; Biomarkers; Child; Child, Preschool; Epilepsy, Temporal Lobe; Fema

2008
A subcortical network of dysfunction in TLE measured by magnetic resonance spectroscopy.
    Neurology, 2007, Dec-11, Volume: 69, Issue:24

    Topics: Adolescent; Adult; Aspartic Acid; Cerebral Cortex; Creatine; Epilepsy, Temporal Lobe; Female; Hippoc

2007
(1)H-MRS profile in MRI positive- versus MRI negative patients with temporal lobe epilepsy.
    Seizure, 2008, Volume: 17, Issue:6

    Topics: Adult; Analysis of Variance; Aspartic Acid; Creatine; Electroencephalography; Epilepsy, Temporal Lob

2008
Increased concentrations of aspartic acid in the cerebrospinal fluid of patients with epilepsy and trigeminal neuralgia: an effect of medication?
    Acta neurologica Scandinavica, 1984, Volume: 70, Issue:2

    Topics: Adolescent; Adult; Amino Acids; Anticonvulsants; Aspartic Acid; Drug Therapy, Combination; Epilepsie

1984
Proton nuclear magnetic resonance spectroscopic imaging of human temporal lobe epilepsy at 4.1 T.
    Annals of neurology, 1995, Volume: 38, Issue:3

    Topics: Adult; Aspartic Acid; Choline; Creatine; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hu

1995
Preliminary observations of metabolic characterization of bilateral temporal epileptic focus, using proton magnetic resonance spectroscopy. Three cases.
    Neurological research, 1994, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Electroencephalography; Epilepsy, Temporal Lobe

1994
Temporal lobe epilepsy: presurgical localization with proton chemical shift imaging.
    Radiology, 1994, Volume: 193, Issue:2

    Topics: Adolescent; Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Electroencephalography; Epilep

1994
Magnetic resonance spectroscopy in temporal lobe epilepsy.
    Neurology, 1994, Volume: 44, Issue:8

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Humans;

1994
1H magnetic resonance spectroscopy of extracts of human epileptic neocortex and hippocampus.
    Neurology, 1993, Volume: 43, Issue:3 Pt 1

    Topics: Adolescent; Adult; Amino Acids; Aspartic Acid; Cerebral Cortex; Child; Epilepsy, Temporal Lobe; Fema

1993
Lateralization of temporal lobe epilepsy based on regional metabolic abnormalities in proton magnetic resonance spectroscopic images.
    Annals of neurology, 1994, Volume: 35, Issue:2

    Topics: Adult; Aspartic Acid; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Magnetic Reso

1994
Proton MR spectroscopy in patients with seizure disorders.
    AJNR. American journal of neuroradiology, 1994, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Cerebral Cortex; Child; Child, Preschool; Choline; Creatine

1994
Neuron loss localizes human temporal lobe epilepsy by in vivo proton magnetic resonance spectroscopic imaging.
    Annals of neurology, 1993, Volume: 34, Issue:6

    Topics: Adult; Aspartic Acid; Brain; Epilepsy, Temporal Lobe; Female; Humans; Magnetic Resonance Imaging; Ma

1993
Proton magnetic resonance spectroscopy in children with temporal lobe epilepsy.
    Annals of neurology, 1996, Volume: 39, Issue:1

    Topics: Adolescent; Aspartic Acid; Child; Child, Preschool; Choline; Creatine; Electroencephalography; Epile

1996
N-acetylaspartate and epilepsy.
    Magnetic resonance imaging, 1995, Volume: 13, Issue:8

    Topics: Adult; Aspartic Acid; Brain Damage, Chronic; Brain Mapping; Child; Choline; Creatine; Dominance, Cer

1995
Symbiosis between in vivo and in vitro NMR spectroscopy: the creatine, N-acetylaspartate, glutamate, and GABA content of the epileptic human brain.
    Magnetic resonance imaging, 1995, Volume: 13, Issue:8

    Topics: Aspartic Acid; Astrocytes; Biopsy; Creatine; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Gluta

1995
Normalization of contralateral metabolic function following temporal lobectomy demonstrated by 1H magnetic resonance spectroscopic imaging.
    Annals of neurology, 1996, Volume: 40, Issue:2

    Topics: Adult; Aspartic Acid; Brain; Cerebellum; Creatinine; Epilepsy, Temporal Lobe; Female; Functional Lat

1996
Temporal lobe epilepsy: correlation of proton magnetic resonance spectroscopy and 18F-fluorodeoxyglucose positron emission tomography.
    Magnetic resonance in medicine, 1997, Volume: 37, Issue:1

    Topics: Adult; Aspartic Acid; Brain; Case-Control Studies; Deoxyglucose; Electroencephalography; Epilepsy, T

1997
Temporal changes in proton MRS metabolites after kainic acid-induced seizures in rat brain.
    Epilepsia, 1997, Volume: 38, Issue:1

    Topics: Animals; Aspartic Acid; Brain; Cell Count; Choline; Creatinine; Dipeptides; Disease Models, Animal;

1997
Metabolic and pathological effects of temporal lobe epilepsy in rat brain detected by proton spectroscopy and imaging.
    Brain research, 1997, Jan-02, Volume: 744, Issue:1

    Topics: Animals; Aspartic Acid; Behavior, Animal; Choline; Creatine; Epilepsy, Temporal Lobe; Excitatory Ami

1997
Temporal lobe epilepsy: bilateral hippocampal metabolite changes revealed at proton MR spectroscopic imaging.
    Radiology, 1997, Volume: 202, Issue:3

    Topics: Adult; Aspartic Acid; Atrophy; Choline; Creatine; Electroencephalography; Epilepsy, Temporal Lobe; F

1997
Interictal 99Tc(m) HMPAO SPECT and 1H MRS in children with temporal lobe epilepsy.
    Epilepsia, 1997, Volume: 38, Issue:3

    Topics: Adolescent; Aspartic Acid; Cerebrovascular Circulation; Child; Child, Preschool; Choline; Creatine;

1997
Hippocampal N-acetylaspartate in neocortical epilepsy and mesial temporal lobe epilepsy.
    Annals of neurology, 1997, Volume: 42, Issue:2

    Topics: Adult; Aspartic Acid; Choline; Creatine; Epilepsies, Partial; Epilepsy, Frontal Lobe; Epilepsy, Temp

1997
Proton magnetic resonance spectroscopic imaging and magnetic resonance imaging volumetry in the lateralization of temporal lobe epilepsy: a series of 100 patients.
    Annals of neurology, 1997, Volume: 42, Issue:5

    Topics: Adult; Aspartic Acid; Creatinine; Electroencephalography; Epilepsy, Temporal Lobe; Female; Functiona

1997
Normalization of neuronal metabolic dysfunction after surgery for temporal lobe epilepsy. Evidence from proton MR spectroscopic imaging.
    Neurology, 1997, Volume: 49, Issue:6

    Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Electroencephalography; Epilepsy, Temporal Lobe

1997
Usefulness of proton MR spectroscopy in the evaluation of temporal lobe epilepsy.
    AJR. American journal of roentgenology, 1998, Volume: 170, Issue:3

    Topics: Adult; Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Hippocampus; Humans; Magne

1998
Reduction in temporal N-acetylaspartate and creatine (or choline) ratio in temporal lobe epilepsy: does this 1H-magnetic resonance spectroscopy finding mean poor seizure control?
    Journal of neurology, neurosurgery, and psychiatry, 1998, Volume: 65, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Electroencephalography; Epilepsy, Temporal Lobe

1998
Quantitative 1H MRS in the evaluation of mesial temporal lobe epilepsy in vivo.
    Magnetic resonance imaging, 1998, Volume: 16, Issue:8

    Topics: Adult; Age of Onset; Aspartic Acid; Case-Control Studies; Choline; Creatine; Epilepsy, Temporal Lobe

1998
Localized proton MRS of the human hippocampus: metabolite concentrations and relaxation times.
    Magnetic resonance in medicine, 1999, Volume: 41, Issue:1

    Topics: Adult; Aspartic Acid; Biomarkers; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Hippocampus; H

1999
Combined measurements of hippocampal N-acetyl-aspartate and T2 relaxation time in the evaluation of mesial temporal lobe epilepsy: correlation with clinical severity and memory performances.
    Epilepsia, 1999, Volume: 40, Issue:10

    Topics: Adult; Aspartic Acid; Brain Diseases; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hippo

1999
Cognitive correlates of 1H MRSI-detected hippocampal abnormalities in temporal lobe epilepsy.
    Neurology, 1999, Dec-10, Volume: 53, Issue:9

    Topics: Adult; Aspartic Acid; Brain Mapping; Cognition Disorders; Creatine; Dominance, Cerebral; Epilepsy, T

1999
Chemical shift imaging spectroscopy findings before and after stereotactic radiotherapy in temporal lobe epilepsy.
    Advances in neurology, 1999, Volume: 81

    Topics: Aspartic Acid; Choline; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Magnetic Re

1999
Relation of interictal spike frequency to 1H-MRSI-measured NAA/Cr.
    Epilepsia, 1999, Volume: 40, Issue:12

    Topics: Adolescent; Adult; Aspartic Acid; Creatine; Electroencephalography; Epilepsies, Partial; Epilepsy, F

1999
Prognostic value of proton magnetic resonance spectroscopic imaging for surgical outcome in patients with intractable temporal lobe epilepsy and bilateral hippocampal atrophy.
    Annals of neurology, 2000, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Aspartic Acid; Atrophy; Brain; Creatine; Dominance, Cerebral; Electroencephalogra

2000
Hippocampal structures: anteroposterior N-acetylaspartate differences in patients with epilepsy and control subjects as shown with proton MR spectroscopic imaging.
    Radiology, 2000, Volume: 214, Issue:2

    Topics: Adult; Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Hippocampus; Humans; Image

2000
Proton magnetic resonance spectroscopy of temporal lobe white matter in patients with histologically proven hippocampal sclerosis.
    Journal of magnetic resonance imaging : JMRI, 2000, Volume: 11, Issue:1

    Topics: Adult; Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Hippocampus; Humans; Magne

2000
Statistically driven identification of focal metabolic abnormalities in temporal lobe epilepsy with corrections for tissue heterogeneity using 1H spectroscopic imaging.
    Magnetic resonance in medicine, 2000, Volume: 43, Issue:3

    Topics: Adult; Aspartic Acid; Creatine; Epilepsy, Temporal Lobe; Female; Hippocampus; Humans; Image Processi

2000
Neuronal dysfunction in children with newly diagnosed temporal lobe epilepsy.
    Pediatric neurology, 2000, Volume: 22, Issue:4

    Topics: Adolescent; Aspartic Acid; Child; Child, Preschool; Creatinine; Epilepsy, Temporal Lobe; Female; Hum

2000
[MRI spectroscopy, T2 relaxometry, and postoperative prognosis in cryptogenic temporal lobe epilepsy].
    Der Nervenarzt, 2000, Volume: 71, Issue:4

    Topics: Adult; Aspartic Acid; Brain; Case-Control Studies; Choline; Dominance, Cerebral; Epilepsy, Temporal

2000
Spatial extent of neuronal metabolic dysfunction measured by proton MR spectroscopic imaging in patients with localization-related epilepsy.
    Epilepsia, 2000, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Aspartic Acid; Child; Creatine; Electroencephalography; Epilepsies, Partial; Epil

2000
Seizure frequency and bilateral temporal abnormalities: a proton magnetic resonance spectroscopy of temporal lobe epilepsy.
    Seizure, 2000, Volume: 9, Issue:4

    Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Creatine; Dominance, Cerebral; Epilepsy, Tempor

2000
Schizophrenia, temporal lobe epilepsy and psychosis: an in vivo magnetic resonance spectroscopy and imaging study of the hippocampus/amygdala complex.
    Psychological medicine, 2000, Volume: 30, Issue:3

    Topics: Adult; Amygdala; Aspartic Acid; Case-Control Studies; Epilepsy, Temporal Lobe; Female; Functional La

2000
Proton magnetic resonance spectroscopic imaging studies in patients with newly diagnosed partial epilepsy.
    Epilepsia, 2000, Volume: 41, Issue:7

    Topics: Adult; Anticonvulsants; Aspartic Acid; Carbamazepine; Creatine; Epilepsies, Partial; Epilepsy, Tempo

2000
Proton MR spectroscopy in patients with acute temporal lobe seizures.
    AJNR. American journal of neuroradiology, 2001, Volume: 22, Issue:1

    Topics: Acute Disease; Adult; Aspartic Acid; Creatine; Epilepsy, Temporal Lobe; Hippocampus; Humans; Lactic

2001
Time course of postoperative recovery of N-acetyl-aspartate in temporal lobe epilepsy.
    Epilepsia, 2001, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Algorithms; Analysis of Variance; Aspartic Acid; Creatine; Epilepsy, Temporal Lob

2001
Lateralizing ability of single-voxel proton mr spectroscopy in hippocampal sclerosis: comparison with mr imaging and positron emission tomography.
    AJNR. American journal of neuroradiology, 2001, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Choline; Dominance, Cerebral; Energy Metabolism; Epilepsy, Tempora

2001
Ictal fear in temporal lobe epilepsy: surgical outcome and focal hippocampal changes revealed by proton magnetic resonance spectroscopy imaging.
    Archives of neurology, 2001, Volume: 58, Issue:5

    Topics: Adult; Aspartic Acid; Choline; Epilepsy, Temporal Lobe; Fear; Female; Hippocampus; Humans; Magnetic

2001
A study of the relationship between metabolism using 1H-MRS and function using several neuropsychological tests in temporal lobe epilepsy.
    Seizure, 2001, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Child; Creatine; Dominance, Cerebral; Electroencephal

2001
Lateralisation with magnetic resonance spectroscopic imaging in temporal lobe epilepsy: an evaluation of visual and region-of-interest analysis of metabolite concentration images.
    Neuroradiology, 2001, Volume: 43, Issue:9

    Topics: Adolescent; Adult; Aspartic Acid; Brain Stem; Choline; Creatine; Electroencephalography; Epilepsy, T

2001
Lateralization and prognostic value of proton magnetic resonance spectroscopy in patients with intractable temporal lobe epilepsy.
    Chang Gung medical journal, 2001, Volume: 24, Issue:12

    Topics: Adolescent; Adult; Aspartic Acid; Child; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hi

2001
Relationships among hippocampal volumetry, proton magnetic resonance spectroscopy, and verbal memory in temporal lobe epilepsy.
    Epilepsia, 2001, Volume: 42, Issue:11

    Topics: Adult; Age of Onset; Aspartic Acid; Creatine; Electroencephalography; Epilepsy, Temporal Lobe; Femal

2001
1H MRSI predicts surgical outcome in MRI-negative temporal lobe epilepsy.
    Neurology, 2002, Mar-12, Volume: 58, Issue:5

    Topics: Adult; Aspartic Acid; Biomarkers; Child; Child, Preschool; Epilepsy, Temporal Lobe; Female; Function

2002
Comparative diagnostic utility of 1H MRS and DWI in evaluation of temporal lobe epilepsy.
    Neurology, 2002, Jun-25, Volume: 58, Issue:12

    Topics: Adolescent; Adult; Aspartic Acid; Chi-Square Distribution; Creatine; Epilepsy, Temporal Lobe; Female

2002
[4-Tesla 1H MR spectroscopy in patients with temporal lobe epilepsy].
    Der Nervenarzt, 1991, Volume: 62, Issue:12

    Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Energy Metabolism; Epilepsies, Partial; Epileps

1991
Bursting in human epileptogenic neocortex is depressed by an N-methyl-D-aspartate antagonist.
    Neuroscience letters, 1987, May-06, Volume: 76, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anticonvulsants; Aspartic Acid; Epilepsy, Temporal L

1987
Aspartic acid aminotransferase activity is increased in actively spiking compared with non-spiking human epileptic cortex.
    Journal of neurology, neurosurgery, and psychiatry, 1988, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Aspartate Aminotransferases; Aspartic Acid; Biopsy; Cerebral Cortex; Epilepsies,

1988